Functional long terminal repeats gene products pol. Medical search. Frequent questions

Initially, piRNAs were described as repeat-associated siRNAs (rasiRNAs) because of their origin from the repetitive elements such as transposable sequences of the genome. (wikipedia.org)
ERVs and related sequences are estimated at ~400,000 copies or 4.6% of the human genome, including genomic proviruses like 5' long terminal repeat (LTR)-gag-pol-env-3' LTR ( 1 ). (frontiersin.org)
On the other hand, LTR-retrotransposons, so called mammalian apparent LTR retrotransposons (MaLRs) represent 3.6% of the genome and lack primer binding sites and gag-pol genes ( 1 ). (frontiersin.org)
The regenerated genome-edited events of Gonja Manjaya showed mutations in the targeted sites with the potential to prevent proper transcription or/and translational into functional viral proteins. (nature.com)
Multiple copies of eBSV viral sequences have become integrated as direct and inverted tandem repeats at a single locus in the B genome of the host during viral infection 5 . (nature.com)
When the banana plants are stressed, the eBSV recombines to produce a functional episomal viral genome and infectious viral particles and as a result the plant develops disease symptoms. (nature.com)
Their ability to move and/or replicate inside the genome is an important evolutionary force, responsible for the increase of genome size and the regulation of gene expression. (sisef.it)
The genome of oncogenic viruses carries genes that have protein products that act as oncoproteins in cell proliferation and transformation. (ac.ir)
SINEs are "non-autonomous" such that amplification and integration is dependent on enzymes derived from the host genome and long interspersed nuclear elements (LINEs) [ 5 ]. (biomedcentral.com)
Notably, the lack of sulfate assimilation genes in the S. fibuligera genome reflects a unique phenotype for Saccharomycopsis clades as natural sulfur auxotrophs. (biomedcentral.com)
The completely sequenced S. fibuligera genome with high-quality annotation and RNA-Seq analysis establishes an important foundation for functional inference of S. fibuligera in the degradation of fermentation mash. (biomedcentral.com)
These early steps consist of a long and perilous journey from the cell surface to the nucleus where the proviral DNA integrates into the host genome. (biomedcentral.com)
The life cycle of retroviruses is arbitrarily divided into two distinct phases: the early phase refers to the steps of infection from cell binding to the integration of the viral cDNA into the cell genome, whereas the late phase begins with the expression of viral genes and continues through to the release and maturation of progeny virions (see Figure 1 for a schematic view of the retroviral life cycle). (biomedcentral.com)
At least 50,000 lncRNAs are expressed from intergenic regions of the human genome, more than twice the number of protein-coding genes [ 5 ]. (biomedcentral.com)

These solo-LTRs contain functional sequences like promoters, enhancers, polyadenylation signals and are frequently located near cellular genes. (frontiersin.org)
Retroviruses have been shown to efficiently delete sequences between repeats as a consequence of the template switching ability of the viral reverse transcriptase. (peerj.com)
To evaluate this approach for deriving safety-modified lentiviral vectors, we created HIV-1 vectors engineered to delete the Rev-response element (RRE) during reverse-transcription by sandwiching the RRE between two non-functional hygromycin phosphotransferase sequences. (peerj.com)
Although HIV-1 based gene transfer vectors lack most of the viral coding sequences, it retains a small portion of the gag sequence, and also contains a 5′ splice donor site upstream of gag and frequently a 3′ splice acceptor site further downstream. (peerj.com)
All gene transfer vectors also contain cis -sequences for encapsidation, reverse-transcription, and integration. (peerj.com)
This ability of the RT to 'jump' is likely responsible for elimination of direct repeats, and sequences inserted between the repeats during reverse transcription. (peerj.com)
In contrast to existing tools, TelomereHunter takes alignment information into account and reports the abundance of variant repeats in telomeric sequences. (biomedcentral.com)
SINE sequences are approximately 70-700 base pairs (bp) averaging about 250 bp [ 1 ] with most organized into an RNA gene-derived region, a di-nucleotide repeat region and terminating in a poly A or poly A/T tail [ 2 - 4 ]. (biomedcentral.com)
All archaeal and many bacterial genomes contain Clustered Regularly Interspaced Short Palindrome Repeats (CRISPR) and variable arrays of the CRISPR-associated ( cas ) genes that have been previously implicated in a novel form of DNA repair on the basis of comparative analysis of their protein product sequences. (biomedcentral.com)

There are two main types of retrotransposons, long terminal repeats (LTRs) and non-long terminal repeats (non-LTRs). (wikipedia.org)
These are termed long terminal repeats (LTRs) that are each a few hundred base pairs long, hence retrotransposons with LTRs have the name long terminal repeat (LTR) retrotransposon. (wikipedia.org)
Due to recombination events between 5' and 3' LTRs, throughout evolution internal genes were lost resulting in ERV solitary LTRs (solo-LTRs). (frontiersin.org)
If present, long terminal repeats (LTRs) have been highlighted in blue. (gydb.org)

The Escherichia coli dnaN159 allele encodes a mutant form of the β-sliding clamp (β159) that is impaired for interaction with the replicative DNA polymerase (Pol), Pol III. (asm.org)
E. coli strains bearing the dnaN159 allele display temperature-sensitive growth ( 14 , 35 , 38 ) and altered DNA polymerase (Pol) usage ( 29 , 38 - 40 ). (asm.org)
These phenotypes appear to result, at least in part, from impaired interactions of the mutant β159 clamp protein with the replicative DNA polymerase, Pol III ( 38 ). (asm.org)
In contrast to these three Pols, which under certain conditions impede growth of the dnaN159 strain ( 29 , 39 , 40 ), presumably by impairing DNA replication, the catalytic DNA polymerase activity of Pol I ( polA ) is essential for viability of the dnaN159 strain ( 38 ). (asm.org)
Direct phenotypic variation is possible by altering gene expression via insertion into coding regions or interference from the internal RNA polymerase promoters in SINEs [ 29 ]. (biomedcentral.com)
The PhiKZ genes are transcribed independently from host RNA polymerase (RNAP) by two RNAPs encoded by the phage. (bvsalud.org)
In all cell lines tested there was equally robust recruitment of total and initiated RNA polymerase II (Pol II). (oncotarget.com)
Specific functional analogies are drawn between several components of CASS and proteins involved in eukaryotic RNAi, including the double-stranded RNA-specific helicase-nuclease (dicer), the endonuclease cleaving target mRNAs (slicer), and the RNA-dependent RNA polymerase. (biomedcentral.com)
They are usually generated from either exons or introns of both protein-coding and non-coding transcripts that are processed by RNA polymerase II (Pol II) [ 12 - 14 ]. (ijbs.com)

The virion RNAP (vRNAP) transcribes early viral genes and must be injected into the cell with phage DNA. (bvsalud.org)
We propose that spatial separation of two phage RNAPs allows coordinated expression of phage genes belonging to different temporal classes. (bvsalud.org)
The association of the cas genes with CRISPR and, especially, the presence, in CRISPR units, of unique inserts homologous to phage and plasmid genes make us abandon this hypothesis. (biomedcentral.com)
Taxonomic classification of those E. ictaluri specific phages must rely on a synthesis of morphological and genomic details, taking into consideration that phage evolution continues to be profoundly directed by lateral gene transfer, and that a rational hierarchical technique of phage classification really should be based within the degree of DNA and protein sequence identity for several genetic loci. (hivprotease-signal.com)
Gene modules which have been proposed for working with as basis of the phage taxonomy method incorporate the DNA packaging head gene cluster, the structural gene archi tecture, and phage tail genes. (hivprotease-signal.com)
The predicted gene products with sequence similarity amongst the eiAU and SSL 2009a phage genomes include things like the putative small tail proteins tail tape mea certain, major tail proteins, major capsid proteins, head morphogenesis, phage terminase tiny subunit, and the phage terminase large subunit. (hivprotease-signal.com)
The substantial terminase subunit which is a structural protein is together with the portal protein viewed as essentially the most universally conserved gene sequence in phages, consequently they are good possibilities to assist in phage classification. (hivprotease-signal.com)
Phylogenetic ana lysis of several phage gene merchandise suggests that these phages are similar to these that infect other Enterobacteria hosts. (hivprotease-signal.com)

The full-length mRNA is used for expression of Gag and Gag-Pro-Pol proteins. (peerj.com)
Lentiviral gene delivery systems consist of packaging (or helper) plasmids that code for viral structural and regulatory proteins, and a gene transfer vector that contains the transgene expression cassette ( Srinivasakumar, 2001 ). (peerj.com)
A cell-penetrant peptide blocking C9ORF72-repeat RNA nuclear export reduces the neurotoxic effects of dipeptide repeat proteins. (le.ac.uk)
We report here functional characterization of two nuclear-encoded chloroplast proteins, Chloroplast protein for Growth and Fertility (CGF1) and CGF2. (biomedcentral.com)
Proteins they encode are associated with chloroplasts through a N-terminal chloroplast-targeting signal in green tissues but also located at plastids in roots and seeds. (biomedcentral.com)
Proteins they encode are associated with chloroplasts through a N-terminal chloroplast-targeting signal. (biomedcentral.com)
The single genomic RNA codes for two replication proteins, p33 and p92 pol , which are sufficient to support TBSV replicon (rep)RNA replication in yeast ( Saccharomyces cerevisiae ) model host [13] , [14] . (prolekarniky.cz)

The non-virion RNAP (nvRNAP) is composed of early gene products and transcribes late viral genes. (bvsalud.org)

OFR2 encodes a protein of ~14 kDa, which is involved in virion assembly due to the presence of predicted N-terminal coiled-coil domain 1 . (nature.com)
gag gene encodes a capsid like protein. (sisef.it)
The Bloom syndrome gene (BLM) encodes a RecQ-like DNA helicase. (lookformedical.com)
SARS-CoV-2 virus encodes 27 genes, whose specific impacts on CM health are not fully understood. (bvsalud.org)

Even though not a outcome of Cdk exercise, the Rb protein is effectively inacti vated in HCMV contaminated cells, and E2F selelck kinase inhibitor responsive genes are very expressed. (thrombin-inhibitor.com)
other specificity is tiny gene activity and distribution browser through the kinase of the R-RasGAP complex ileal to suitable or through the functionality of RhoA. (evakoch.com)

High ERV-K env total protein expression of all tumor subtypes significantly correlated with low tumor grading and a longer disease specific survival using multivariable analyses. (frontiersin.org)
DNA methylation and histone modifications play a central role in the epigenetic regulation of gene expression and cell differentiation. (cipsm.de)
Take control of microRNA expression for powerful functional screening of hundreds or thousands of microRNAs. (horizondiscovery.com)
However the gag/pol coding sequence serves as an intron and is spliced out for expression of Env. (peerj.com)
Upon depletion of RBPJ using CRISPR/Cas9, we observed specific upregulation of Notch target gene expression. (mdpi.com)
We found that knockdown of MDM2 in G/G cells moderately increased expression of subsets of p53 target genes without increasing p53 stability. (oncotarget.com)
Despite extensive studies of specific genes that regulate this process, the global changes in transcript expression profiles at the point when a vegetative meristem transitions into an inflorescence have not been reported. (biomedcentral.com)
We analyzed gene expression during Arabidopsis thaliana meristem development under long day conditions from day 7 to 16 after germination in one-day increments. (biomedcentral.com)
This analysis revealed a developmental time point between 10 and 12 days after germination where FLC expression had decreased but LFY expression had not yet increased, which was characterized by a peak in the number of differentially expressed genes. (biomedcentral.com)
We discovered an unprecedented burst of differential expression of cell cycle related genes at one particular point during transition to flowering. (biomedcentral.com)
Four latency types (0, I, II, III) are defined depending on the expression pattern of EBV latent genes, and at the same time are linked to a particular tumor type [ 6 , 7 ]. (ijbs.com)
miRNAs are able to post-transcriptionally control gene expression by binding to target mRNAs [ 15 ]. (ijbs.com)
These elements are involved in control of gene expression which governs the phenotype and also plays role in disease biology. (researchgate.net)
Of considerable interest, we found that expression of elncRNAs, but not plncRNAs, is associated with enhanced expression of neighboring protein-coding genes during erythropoiesis. (biomedcentral.com)
Different correlations between the levels of elncRNAs, plncRNAs and expression of neighboring genes suggest that functional lncRNAs from the two classes may play contrasting roles in regulating the transcript abundance of local or distal loci. (biomedcentral.com)

These genes overlap so they encode a protease that processes the resulting transcript into functional gene products. (wikipedia.org)

Some lncRNAs originate from intragenic enhancers which, when active, behave as alternative promoters producing transcripts that are processed using the canonical signals of their host gene. (biomedcentral.com)

It is thought that staying in eukaryotic genomes for such long periods gave rise to special insertion methods that do not affect eukaryotic gene function drastically. (wikipedia.org)
There are two major, distinct forms of regulatory small RNAs involved in eukaryotic gene silencing: small interfering (si) RNAs and micro (mi) RNAs. (biomedcentral.com)

A terminal section of a chromosome which has a specialized structure and which is involved in chromosomal replication and stability. (lookformedical.com)
[ 1 ] As this gene is carried on the X chromosome, the disease usually manifests in males and is transmitted by females who carry the causative mutation on one of their X chromosomes. (medscape.com)

Dicer cleaves long dsRNA molecules into short, 21-22 nucleotide duplexes which are subsequently unwound by the RISC to yield mature siRNAs. (biomedcentral.com)
Along with co-ordinate (location) details of S/MARs, the dataset also revealed details of S/MAR features, namely, length, inter-SMAR length (the chromatin loop size), nucleotide repeats, motif abundance, chromosomal distribution and genomic context. (researchgate.net)

It is proposed that unique inserts of CRISPR, some of which are homologous to fragments of bacteriophage and plasmid genes, function as prokaryotic siRNAs (psiRNA), by base-pairing with the target mRNAs and promoting their degradation or translation shutdown. (biomedcentral.com)

In addition to having a role in the suppression of genomic transposons, various roles of piRNAs have been recently reported like regulation of 3' UTR of protein-coding genes via RNAi, transgenerational epigenetic inheritance to convey a memory of past transposon activity, and RNA-induced epigenetic silencing. (wikipedia.org)
Comparative-genomic analysis of CRISPR and cas genes leads to the hypothesis that the CRISPR-Cas system (CASS) is a mechanism of defense against invading phages and plasmids that functions analogously to the eukaryotic RNA interference (RNAi) systems. (biomedcentral.com)

Long strands of repetitive DNA can be found at each end of a LTR retrotransposon. (wikipedia.org)
Gag gene products associate with other retrotransposon transcripts to form virus-like particles. (wikipedia.org)
This results in a retrotransposon flagged by long terminal repeats at its ends. (wikipedia.org)

After flowering initiation, the action of LFY and AP1 , as well as CAULIFLOWER ( CAL ) results in the upregulation of genes that control floral organ identity [ 20 - 23 ]. (biomedcentral.com)

Although epigenetically silenced, endogenous retroviral (ERV) genes become activated in tumors and function to ignite immune responses. (frontiersin.org)
Circular RNAs (circRNAs) were first found in RNA (ribonucleic acid) viruses as a viroid as early as 1976 [ 1 ] and were later found to be an endogenous RNA splicing product in eukaryotes in 1979 as well [ 2 ]. (biomedcentral.com)

However, unlike other oncogenic retroviruses, deltaretroviruses have an additional region, tax (trans-activating region of the X gene), which has regulatory functions and is oncogenic to host cells. (cdc.gov)

several new functional and structural predictions are described. (biomedcentral.com)
Scaffold/matrix attachment regions (S/MARs) are DNA elements that serve to compartmentalize the chromatin into structural and functional domains. (researchgate.net)
The RPA gene is the structural excretion loss-of-function, However Binding it from the corresponding growth( De Laat et al. (evakoch.com)

Elucidating these mechanisms and identifying which cellular factors are exploited by the retroviruses and which hinder their life cycle, will certainly lead to the discovery of new ways to inhibit viral replication and to improve retroviral vectors for gene transfer. (biomedcentral.com)
Fully elucidating the early steps of retrovirus replication is therefore crucial not only for identifying new antiretroviral drugs, but also for improving the design of retroviral vectors for gene therapy. (biomedcentral.com)

At least 60 genes have been described as participants in flowering regulation [ 9 ]. (biomedcentral.com)

A novel key feature is the extraction of singleton telomere variant repeats, which improves the identification and subclassification of the alternative lengthening of telomeres phenotype. (biomedcentral.com)
Our findings indicate that elevated levels of Pol I partially suppress the temperature-sensitive growth phenotype of the dnaN159 strain. (asm.org)

Mammalian transcriptomes contain thousands of long noncoding RNAs (lncRNAs). (biomedcentral.com)

Deletion of the RRE during reverse-transcription lead to the reconstitution of a functional hygromycin phosphotransferase gene in the target cell. (peerj.com)

In addition, strains bearing the dnaN159 allele require functional Pol I for viability. (asm.org)
I've also (via a contact at ARM) run high-performance code on the later A57, it's about 3x faster than the A53 and is competitive with the Core2 on my 2010 Macbook, i.e. is getting close to viability in terms of that market, but AFAICT remains a niche product. (nakedcapitalism.com)

These data suggest that further investigation of the potential of antibody-based therapeutic strategies for long-term suppression of HIV is warranted, including in individuals off ART and with low viral load. (nature.com)

DNA transposons encode a transposase which, when translated, catalyses the excision of the transposase gene and its flanking region and its insertion into a different genomic location: a 'jumping' DNA element. (wikipedia.org)
Despite its long history of use in food fermentation and bioethanol production, very little is known about the basic physiology and genomic features of S. fibuligera . (biomedcentral.com)

Pol gene products include enzymes reverse transcriptase, integrase and ribonuclease H domains. (wikipedia.org)
Enzymes that catalyze the release of mononucleotides by the hydrolysis of the terminal bond of deoxyribonucleotide or ribonucleotide chains. (lookformedical.com)
The amylolytic yeast Saccharomycopsis fibuligera has served as a good source of enzymes and genes involved in saccharification. (biomedcentral.com)
The gene inventory facilitates the discovery of new genes applicable to the production of novel valuable enzymes and chemicals. (biomedcentral.com)

These two classes of 5′ capped and polyadenylated RNA transcripts are indistinguishable with regard to their length, number of exons or transcriptional orientation relative to their closest neighboring gene. (biomedcentral.com)

John T, Pires E, Hester SS, Salah E, Hopkinson RJ, Schofield CJ Formaldehyde reacts with N-terminal proline residues to give bicyclic aminals. (le.ac.uk)
It is structurally different from TELOMERIC REPEAT BINDING PROTEIN 1 in that it contains basic N-terminal amino acid residues. (lookformedical.com)

This bleeding is painful and leads to long-term inflammation and deterioration of the joint (typically the ankles in children, and the ankles, knees, and elbows in adolescents and adults), resulting in permanent deformities, misalignment, loss of mobility, and extremities of unequal lengths. (medscape.com)
SARS-CoV-2 infection and the overexpression of Nsp6, Nsp8, or M coherently upregulated genes associated with apoptosis and immune/inflammation pathways, whereas downregulated genes linked to heart contraction and functions. (bvsalud.org)

Exceptionally, a minority of miRNAs are derived from RNA Pol III transcripts. (ijbs.com)

Importantly, it was found that ginkgolic acid could significantly suppress the transcription of PRV late genes, while the transcription of viral immediate early and early genes was not affected. (bvsalud.org)
Taken together, a novel PRV replication inhibitor, ginkgolic acid, which worked through suppressing the transcription of the late genes, was found in this study. (bvsalud.org)
We hypothesized that MDM2 in these cells inhibited transcription initiation at the p53 target genes p21 and puma . (oncotarget.com)
Surprisingly, following etoposide treatment transcription initiation occurred at the compromised target genes in MANCA and A875 cells similar to the T/T ML-1 cell line. (oncotarget.com)

Since Pol I is a multifunctional protein that participates in DNA replication, as well as numerous DNA repair pathways, several possibilities exist, including Okazaki fragment maturation ( 21 , 31 ) and single-stranded DNA (ssDNA) gap repair ( 16 , 22 ). (asm.org)
Since Pol III replication is abated in strains bearing the dnaN159 allele ( 14 , 35 , 38 ), due to the impaired ability of β159 to interact with the α catalytic subunit of Pol III ( 38 ), we hypothesized that the requirement for Pol I function in the dnaN159 strain might stem from its ability to augment Pol III function in DNA replication. (asm.org)

The Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway evaluation suggested that furthermore to Wnt and changing growth aspect (TGF) signaling pathways, that have been reported in response to follicle formation broadly, another mixed band of signaling pathways that regulate lipid synthesis and fat burning capacity, like the phosphatidylinositol signaling program and glycerolipid signaling and fat burning capacity, are Gemzar biological activity in charge of follicle formation also. (clinical-research-informatics.com)

Importantly, Pol I function is not required by the isogenic dnaN + strain ( 38 ), indicating that Pol I plays one or more essential roles in the dnaN159 strain. (asm.org)

amino-terminal download supports to follow triple and also active fractions appearing on the complex reticulum. (evakoch.com)

During the long journey from the cell surface to the nucleus, retroviruses will face multiple obstacles, since in addition to finding a path through the cytoplasm to the nucleus they have to cross two main barriers, the plasma and nuclear membranes, whilst at the same time avoiding or counteracting cellular defences that can interfere with many of these steps. (biomedcentral.com)

Gene Ontology (GO) enrichment analysis of these genes identified an overrepresentation of genes related to the cell cycle. (biomedcentral.com)
Analysis of mutants with abnormal flowering time has allowed the identification of genes controlling floral transition [ 8 ]. (biomedcentral.com)
For an epub neue technologien im gesundheitswesen rahmenbedingungen und line, errors describe well eukaryotic, as the other flexibility in a chapter are two methods using the system validation, well in construct In event for initial group matrix to assemble interface in a analysis gene of the second information, a subject survival must permit longitudinal in the reduction. (naturheilpraxis-gisbert-fussek.de)

EBV can establish life-long latent infection in host due to the balance between EBV and host immune system. (ijbs.com)
EBV can not be completely cleared once entry into the host cells and ultimately establishes life-long latent infection in host, indicating that EBV has developed elaborate strategies to evade host immune surveillance [ 4 ]. (ijbs.com)

The photoperiod-dependent pathway of floral promotion converges on the gene CONSTANS ( CO ), which is known to be expressed in a circadian manner [ 10 ]. (biomedcentral.com)

non-LTR and LTR elements characterized, respectively, by the absence or presence of long repeated regions flanking the ORFs core. (sisef.it)
Taken together, these results suggest that (i) the β clamp-Pol I interaction may be important for proper Pol I function in vivo and (ii) in the absence of Pol I, ssDNA gaps may persist in the dnaN159 strain, leading to lethality of the dnaN159 Δ polA strain. (asm.org)

However, the proximity of CRISPR and cas genes strongly suggests that they have related functions which is hard to reconcile with the repair hypothesis. (biomedcentral.com)

An abnormal congenital condition, associated with defects in the LAMIN TYPE A gene, which is characterized by premature aging in children, where all the changes of cell senescence occur. (lookformedical.com)
functional ATP by a full cell signal reticulum 1. (evakoch.com)
also, the 5' download volatility trading of the cytoplasm is involved actually by cationic end-product by the RNase proximity water cell, which has a direct RNA( RNA H1 in pathways) and at least 10 Fructose-6-phosphate nucleus( activated in Jarrous 2002, Xiao et al. (evakoch.com)

XLS 97 kb) 12861_2017_153_MOESM8_ESM.xls (98K) GUID:?B2FE5241-0444-4D48-99D4-D5E55E4120EF Extra file 9: Desk S7: Target genes of the very best portrayed 18 miRNAs. (clinical-research-informatics.com)
Upon download climate change forests and redd lessons for institutional design 2012 of production tryptamine A( PKA) millions in the member of Gallery, the referred PKA Indian zygotes function N-terminal conversion and target monomers of general extracellular causes. (evakoch.com)

However, some seed-match regions that contain single mismatches, bulges, G:U wobbles, insertion or deletion are functional sites [ 18 ]. (ijbs.com)

Buehl CJ, Goff NJ, Hardwick SW, Gellert M, Blundell TL, Yang W, Chaplin AK , Meek K. Two distinct long-range synaptic complexes promote different aspects of end processing prior to repair of DNA breaks by non-homologous end joining. (le.ac.uk)
Vascular lesions of the hand are common and are distinct from vascular lesions elsewhere because of the terminal vascular network in this region, the frequent hand exposure to trauma and microtrauma, and the superficial location of the lesions. (springer.com)

The cloning and sequencing of amplification products and a Cleaved Amplified Polymorphisms (CAPs) approach on the identified retrotransposons, showed a high level of diversity among the multiple copies of both elements. (sisef.it)

1 Total constructs includes 110 non-targeting and gene-specific shRNA constructs. (horizondiscovery.com)
article{, title = {Comprehensive features of natural and in vitro selected GNRA tetraloop-binding receptors}, author = { C. Geary and S. Baudrey and L. Jaeger}, year = {2008}, date = {2008-01-01}, journal = {Nucleic Acids Res}, volume = {36}, number = {4}, pages = {1138-52}, abstract = {Specific recognitions of GNRA tetraloops by small helical receptors are among the most widespread long-range packing interactions in large ribozymes. (cnrs.fr)
Specific recognitions of GNRA tetraloops by small helical receptors are among the most widespread long-range packing interactions in large ribozymes. (cnrs.fr)

Hemophilia B is caused by a variety of defects in the F9 gene. (medscape.com)

Anatomy13

Organisms56

Diseases12

Chemicals and Drugs68

Analytical, Diagnostic and Therapeutic Techniques and Equipment19

Phenomena and Processes95

Information Science4

Genome14

Sequences9

LTRs4

Polymerase9

Phage8

Proteins7

Viral genes1

Encodes4

Kinase2

Expression15

Protease1

Promoters1

Eukaryotic gene2

Chromosome2

Nucleotide2

Bacteriophage1

RNAi2

Retrotransposon3

Upregulation1

Endogenous2

Oncogenic1

Structural3

Retroviral vectors2

Regulation1

Phenotype2

RNAs1

Reverse transcription1

Viability2

Therapeutic strategies1

Genomic2

Enzymes4

Transcriptional1

Residues2

Inflammation2

Transcripts1

Transcription4

REPLICATION2

Regulate1

Importantly1

Amino1

Retroviruses1

Analysis3

Immune2

Pathway1

Absence2

CRISPR1

Cell3

Target2

Deletion1

Distinct2

Amplification1

Specific3

Defects1