• The α-crystallin family and βγ-crystallins compose the major family of proteins present in the crystalline lens. (wikipedia.org)
  • Identified recently as part of the non-LEE-encoded (Nle) effector set, this family remained uncharacterised and shared no sequence homology to other proteins including those of known function. (rcsb.org)
  • While most membranous and disease related proteins are regulated by miRNAs, the G-protein coupled receptor (GPCR) family is an exception, being mostly unregulated by miRNAs. (frontiersin.org)
  • The protein product of the translocase gene demonstrated characteristics typical for members in this family of proteins, including 12 transmembrane helices and an isoelectric point of 9.4. (usda.gov)
  • Bioinformatic analysis of the protein revealed 12 transmembrane helices and an isoelectric point of 9.4, both of which are characteristic of this family of proteins. (usda.gov)
  • The mGluRs possess the seven putative transmembrane domains which are characteristic of GPCR proteins. (bdbiosciences.com)
  • The major facilitator superfamily (MFS) of membrane proteins represents the largest family of secondary transporters with members from Archaea to Homo sapiens. (embl.de)
  • In this regard, his lab has identified a novel family of hematopoietic cell surface proteins, called the CD34 family, and shown that these are essential for a number of developmentally important processes. (ubc.ca)
  • Enabling functional integration implies improving non-clinical functions, for example, using technology to establish shared data platforms to share information about older people's needs. (who.int)
  • Individuals with DS or trisomy 21 develop a clinical syndrome of dementia with clinical and neuropathologic characteristics almost identical to those of AD as described in individuals without DS. (medscape.com)
  • To identify the prevalence of homebound elderly people, and the influence of sociodemographic and economic characteristics on their functional dependency. (bvsalud.org)
  • Functional independence was measured by the Functional Independence Measure (FIM) and the sociodemographic and economic variables were collected by a questionnaire developed by the authors. (bvsalud.org)
  • Binary logistic regression was used to determine the influence of the sociodemographic and economic characteristics on the risk of being functionally dependent. (bvsalud.org)
  • The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. (thermofisher.com)
  • Applications Reported: PK136 has been reported for use in flow cytometric analysis, depletion of NK cells, and in vitro functional studies. (thermofisher.com)
  • Due to an inability to genetically manipulate Las at the present time, the translocase (tlc) open reading frame was cloned and expressed in Escherichia coli to determine if this putative gene was in fact functional. (usda.gov)
  • The relationship between these families is one of classic gene duplication and divergence, from the small HSP family, allowing adaptation to novel functions. (wikipedia.org)
  • This study sought to analyse KCNJ2 in patients with familial ATS and to determine the functional characteristics of the mutated gene. (nih.gov)
  • Although the loss of several gene families was detected in Cucurbitaceae, the gene families expanded in five species that experienced a WGD event comparing with grape. (unl.edu)
  • Finally, we conducted a comprehensive analysis of the TCP gene family and identified 16 tendril-related ( TEN ) genes in 11 Cucurbitaceae species. (unl.edu)
  • Interestingly, the characteristic sequence changed from CNNFYFP to CNNFYLP in the TEN gene ( Bhi06M000087 ) of Benincasa hispida . (unl.edu)
  • Furthermore, we identified a new characteristic sequence, YNN, which could be used for TEN gene exploitation in Cucurbitaceae. (unl.edu)
  • In conclusion, this study will serve as a reference for studying the relationship between gene family evolution and genome duplication. (unl.edu)
  • NKR-P1A, the receptor encoded by the KLRB1 gene, recognizes Lectin Like Transcript-1 (LLT1) as a functional ligand. (thermofisher.com)
  • However, they exhibit no additional sequence homology to any member of other GPCR families. (bdbiosciences.com)
  • To assess the predictive capacity of a 10-minute compact geriatric assessment for other outcomes within 12 months, including functional decline, intrinsic capacity decline, hospital readmission, presence of frailty syndrome, as measured by the incidence of these events after hospital discharge, and in comparison to a reference comprehensive geriatric assessment. (who.int)
  • This functional ability is determined by the intrinsic capacity of the individual (that is, the combination of all the individual's physical and mental - including psychosocial - capacities), the environments he or she inhabits (understood in the broadest sense and including physical, social and policy environments), and the interaction between these. (who.int)
  • Although these questions have been used to estimate prevalence of functional disabilities overall, as well as types of functional disabilities (disability type), no study has yet investigated the characteristics of U.S. adults by number of disability types. (cdc.gov)
  • Male sex, higher income, lower academic attainment and higher number of friends or family members who smoke were associated with increased prevalence of smoking. (who.int)
  • The prevalence of functional dependency was very high in this sample, and since the presence of a caregiver was the strongest and significant predictor of functional dependency, we suggest that guidance and support should be offered to caregivers, followed by a family healthcare strategy, to make consistent efforts with the objective of improving functional recovery and independence of homebound elderly. (bvsalud.org)
  • A recent study reported a low prevalence of movements with no structural or biochemical disorder, functional constipation in children with good adherence painful defecation and sometimes faecal incontinence (3) . (who.int)
  • METHODS We administered candidate items for the new instrument and also the Test of Functional Health Literacy in Adults (TOFHLA) to English-speaking and Spanish-speaking primary care patients. (annfammed.org)
  • Understanding the demographic and socioeconomic characteristics of working-age adults with disabilities, including adults with multiple disabilities, might help to further the inclusion of persons with disabilities in public health programs and policies, thereby increasing their social participation. (cdc.gov)
  • CDC analyzed data from the family component of the National Health Interview Survey (NHIS) for the years 2011-2014 to estimate the percentage of adults aged 18-64 years with one, two, three, or four or more disability types, by selected demographic and socioeconomic characteristics. (cdc.gov)
  • NMES-1 produced information on a broad range of issues such as the number and characteristics of the uninsured and the underinsured, the tax implications of excluding employer-paid premiums for health insurance from employee income, and the differences among socioeconomic and demographic groups with respect to the use of health services. (cdc.gov)
  • Our findings showed that greater work -to- family conflict was related to higher comorbidity and greater disability over time, controlling for other known predictors of health ( employment status, total household income, living arrangement , marital status, depressive symptoms, and baseline demographic characteristics). (cdc.gov)
  • This is the first study to investigate the characteristics of U.S. adults by number of functional disability types. (cdc.gov)
  • A brief examining a Family and Individual Needs for Disability Supports (FINDS) survey subsample of 807 caregivers of adults with intellectual and/or developmental disabilities (IDD), ages 18 and. (umn.edu)
  • A brief comparing caregiving experiences of family caregivers for adults with intellectual and developmental disabilities (IDD) with those of caregivers who responded to the Caregiving in the U.S. (umn.edu)
  • One is the Test of Functional Health Literacy in Adults (TOFHLA), 27 , 28 which is the instrument most often used for literacy assessment in health care research. (annfammed.org)
  • Given that congenital hallux valgus is extremely rare, our finding that hallux valgus is heritable in adults raises questions as to which anatomical or functional characteristics are inherited that may predispose to the development of the condition in later life. (medscape.com)
  • Eight metabotropic glutamate receptors (mGluR1-8) and several Ca[2+] sensing receptors belong to a novel G-protein coupled receptor (GPCR) family. (bdbiosciences.com)
  • The signs and symptoms of this condition vary widely among affected individuals, even within the same family. (medlineplus.gov)
  • This checklist is designed determine whether a child or adolescent has symptoms characteristic of ADHD, their severity, and which functional areas are most affected. (mentalhelp.net)
  • Function- also be useful in improving functional gastrointestinal al constipation is characterized by a slowing of bowel symptoms. (who.int)
  • SPC58xEx builds on the legacy of the SPC5x family, while introducing new features coupled with higher throughput to provide substantial reduction of cost per feature and significant power and performance improvement (MIPS per mW). (st.com)
  • Slit-lamp examination was performed on the probands and available family members to identify characteristic features of MECD. (molvis.org)
  • Other characteristic features of the serif are the small contrast of strokes, open apertures and brutal serifs, the length of which decreases in proportion to the decrease in boldness. (fonts.com)
  • The family has 29 OpenType features, including localization features. (fonts.com)
  • Usually, the characteristic dysmorphic features lead to an early diagnosis, no later than age 3 years. (medscape.com)
  • No other work - family variables significantly predicted the health outcomes. (cdc.gov)
  • Herein we report on a pilot study involving twelve participants with ALS and nine age-matched healthy controls who underwent high-resolution resting state functional magnetic resonance imaging at an ultra-high field of 7 Tesla. (biorxiv.org)
  • Forty-eight percent of the participants were functional dependents, 80% were female, 72% belonged to the fourth age, 74% were white, 63% were widowed, 78% had retired, 90% had children, 83% had a caregiver, 52% had low education and 40% had low income. (bvsalud.org)
  • Post-discharge follow-up data collection will be carried out using telephone interviews and the application of a semi-structured questionnaire with participants or family members. (who.int)
  • Of those participants, family information was available for 1370. (medscape.com)
  • In contrast, religion, negative health effects, A pilot-tested structured questionnaire, bad taste and smell, adverse physiological prepared specifically for the study, was responses and issues related to family are administered by the study coordinator who considered good reasons for not smoking asked the students to respond freely and [ 22,23 ]. (who.int)
  • A brief examines a Family and Individual Needs for Disability Supports (FINDS) survey subsample of 388 caregivers of minor children with intellectual and/or developmental disabilities (IDD), ages. (umn.edu)
  • Functional analysis revealed impaired PP2A A/C-subunit binding, decreased short linear interaction motif-dependent substrate binding or both-with the most severe phenotypes associated with variants that completely retained one of these binding characteristics and lost the other-further supporting a dominant-negative disease mechanism. (bmj.com)
  • PolyPhen-2, SIFT, and PANTHER were used to predict the functional impact of identified variants. (molvis.org)
  • Two integrated and highly predictive functional analysis-based procedures for the classification of MSH6 variants in Lynch syndrome. (cdc.gov)
  • Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. (thermofisher.com)
  • One remarkable characteristic of the MFS is the high sequence variety within the superfamily. (embl.de)
  • Characteristics predicting recommendation for familial breast cancer referral in a cohort of women from primary care. (cdc.gov)
  • Notwithstanding limitations in accuracy and resolution of the data available from public sources, we pinpoint significant trends exploiting information in curves and shapes with Functional Data Analysis techniques. (nature.com)
  • 75 to define limited literacy, we plotted receiver-operating characteristics (ROC) curves and calculated likelihood ratios for cutoff scores on the new instrument. (annfammed.org)
  • In order for new strategies to be developed towards functional dependence of the homebound population, there is a need to understand which factors can predict and influence this functional dependence. (bvsalud.org)
  • NleG homologues constitute the largest family of Type 3 effectors delivered by pathogenic E. coli, with fourteen members in the enterohaemorrhagic (EHEC) O157:H7 strain alone. (rcsb.org)
  • A missense mutation (T75R) of Kir2.1, located in the highly conserved cytoplasmic N-terminal domain, was identified in three affected members of this family. (nih.gov)
  • These design characteristics increase the usability and legibility tremendously. (linotype.com)
  • Unlike functional testing, which verifies the applicable requirements, non-functional testing assesses factors such as performance, scalability, reliability, usability, security, and other qualities that define the behavior and characteristics of the system. (assorttech.com)
  • 2 The anatomic characteristics of the knee, its exposure to external forces and the functional demands placed on the joint may explain the frequency of injury. (aafp.org)
  • There was no significant difference regarding functional independence defined by modified Rankin Scale (mRS) ≤ 2 at 3 months ( P = 0.12), in-hospital mortality ( P = 0.37), mortality at 3 months ( P = 0.73), and symptomatic intracerebral hemorrhage ( P = 0.24) among groups. (springer.com)
  • Parents of a child with autism spectrum disorder (ASD) face specific challenges in parenting, but concrete parenting behavior has never been properly investigated in these families. (springer.com)
  • Parameters in non-functional testing are the inputs or variables used to specify the conditions and data values for executing test cases and evaluating the behavior of the software being tested. (assorttech.com)
  • Performance testing evaluates whether the system fulfills the non-functional requirements specified in the SRS document by examining the system's behavior and effectiveness in terms of response time, throughput, and other factors. (assorttech.com)
  • These groups include poor and low income families, the elderly, the functionally impaired, and black and Hispanic minorities. (cdc.gov)
  • A few studies have investigated functional capacity in the Brazilian elderly population 4-6 and have shown that 19% to 23% are functionally dependent 7,8 . (bvsalud.org)
  • Moreover, it will provide rich genetic resources for functional Cucurbitaceae studies in the future. (unl.edu)
  • Olives, olive oil and cereals are important functional constipation include genetic disposition, low in the Mediterranean dietary culture and are known to socioeconomic status, impaired mobility and insufficient have been grown and used in the region since ancient daily fibre intake (5) . (who.int)
  • These questions have been used previously to assess functional disability overall and individual disability types. (cdc.gov)
  • Non-functional testing is essential to assess the overall quality and user experience of the software beyond its functional capabilities. (assorttech.com)
  • The health system is one aspect of the total system of support that an older person will need as they face functional decline. (who.int)
  • E2 and E3 showed distinct taxonomic and functional characteristics, while E1 represented an intermediate state. (aacrjournals.org)
  • The functional diversity of glutamate is exemplified by two distinct groups of glutamate receptors: ionotropic and metabotropic. (bdbiosciences.com)
  • METAS Master Chronometer certification is comprehensive and covers the main functional characteristics of a watch including precision, resistance to magnetic fields, waterproofness and power reserve. (tudorwatch.com)
  • Its objective is to ensure the application meets the specified non-functional requirements and performs optimally under various conditions and user scenarios. (assorttech.com)
  • Other topics may include functional difficulties, transition services, shared decision-making, and satisfaction with care. (census.gov)
  • Using the Xenopus oocyte expression system and whole cell voltage clamp analyses, we found that the T75R mutant was non-functional and possessed a strong dominant negative effect when co-expressed with the same amount of wild type Kir2.1. (nih.gov)
  • The most common type of ovarian cyst, known as a functional or ovulatory cyst, develops every month when you ovulate. (healthline.com)
  • Hierophant is a humanist serif type family that has the heritage of classic Old Style and Transitional type while having the crisp lines and functionality of contemporary fonts. (fonts.com)
  • Without hormone replacement therapy, affected individuals do not develop secondary sexual characteristics such as pubic hair, breast growth in women, or a deepening voice in men. (medlineplus.gov)
  • Among the nanoplatforms designed to address these objectives, polymer-based NPs have attracted much interest mainly because of the versatile characteristics of polymers allowing adjustment of the physico-chemical and biological properties of the corresponding nanocarriers. (frontiersin.org)
  • These factors include access to - and quality of - health care, family interactions, parental health, neighborhood characteristics, as well as school and after-school experiences. (census.gov)
  • This survey provides extensive information on health expenditures by or on behalf of families and individuals, the financing of these expenditures, and each person's use of services. (cdc.gov)
  • Household Survey Each family in the Household Survey was interviewed four times over a period of 16 months to obtain information about the family's health and health care during calendar year 1987. (cdc.gov)
  • Baseline data on household composition, employment, and insurance were updated at each interview, and information was obtained on illnesses, use of health services, and health expenditures for each family member. (cdc.gov)
  • Every unique person, their family and community are at the heart of the health and social systems. (who.int)
  • Older persons and their families should be fully informed and empowered to take an active part in health care decision-making. (who.int)
  • Thus, people aim to maintain functional ability and improved quality of life, while managing health problems by oneself. (who.int)
  • Older persons and their families may have insufficient information to participate in health decision-making that affects their quality of life. (who.int)
  • Social change and intergenerational relations are occurring in many ASEAN countries affecting expectations for public health services and the role of families in care provision for older persons. (who.int)
  • Integrated care requires strong coordination across many stakeholders - families, health service providers, community services, local and national governments. (who.int)
  • The effects of work - family experiences on health among older work ers. (cdc.gov)
  • this may be achieved through the Family Health Strategy (FHS) that works as a bridge between the health system and the elderly 3 , it has evolved into a robust approach to providing primary care for defined populations by deploying interdisciplinary health care teams. (bvsalud.org)
  • Family health teams are organized geographically, covering populations of up to 1000 households each, with no overlap or gap between catchment areas. (bvsalud.org)
  • Each FHS team member has defined roles and responsibilities, and national guidelines help structure FHS responses to most health problems (Brazil's Family Health Strategy - Delivering Community-Based Primary Care in a Universal Health System. (bvsalud.org)
  • Functional constipation is often seen in children, affecting quality of life and imposing a considerable bur- den on health care services. (who.int)
  • According to the World report on ageing and health, healthy ageing is defined as "the process of developing and maintaining the functional ability that enables well-being in older age. (who.int)
  • This paper describes a functional genomics study of an ATP/ADP translocase in Candidatus Liberibacter asiaticus (Las), the phloem-restricted, gram-negative alphabacterium that causes the devastating disease of citrus known as huanglongbing. (usda.gov)
  • The study coordinator visited the acceptance, family history of smoking, selected rooms between 09:00 and 11:00 lower educational level of parents and the hours and explained the purpose of the desire to attain high personality profile [ 22 ]. (who.int)
  • Cross-sectional study with 178 homebound elderly people assisted by a family healthcare unit in Vitória, ES, Brazil. (bvsalud.org)
  • This study aimed to evaluate the relationship between functional constipation and adherence to the Mediterranean diet in Turkish children aged 6-18 years. (who.int)
  • In this case-control study, 221 children with functional constipation (cases) were selected from a paediatric gastroenterology clinic between May 2018 and September 2019, and 230 children without constipation (controls) were randomly selected from those attending a well-child check-up. (who.int)
  • The purpose of this study was to investigate position to constipation in children with low vegetable, the relationship between functional constipation and fruit and cereal consumption and low fibre intake (6,7) . (who.int)
  • Clinicians had suspected that hallux valgus ran in families, but this is the first study to document that heritability. (medscape.com)
  • Since most individuals with intellectual and/or developmental disabilities live at home, engaging families in social. (umn.edu)
  • However, there is not enough evidence regarding the functional capacity of homebound elderly people. (bvsalud.org)
  • The sequences identity ranges around 12-18% but regions of functional similarity (e.g., substrate- or H-binding sites) align for only very closely related MFS transporters. (embl.de)
  • Our findings revealed that the recent WGD events that had occurred in Cucurbitaceae played important roles in the expansion of most TF families. (unl.edu)
  • The TT Livret font family consists of 32 faces: 15 upright, 15 oblique, and 2 variable fonts. (fonts.com)
  • Family physicians are frequently called on to evaluate patients who have acute knee injuries. (aafp.org)
  • Knowing the characteristics of persons living with multiple disability types is important for understanding the overall functional status of these persons. (cdc.gov)
  • For example, alpha, beta, and delta crystallins are found in avian and reptilian lenses, and the alpha, beta, and gamma families are found in the lenses of all other vertebrates. (wikipedia.org)
  • Arenaviruses have been divided into 2 groups based on whether the virus is found to infect Old World (ie, Eastern Hemisphere) rodents (family Muridae, subfamily Murinae) or New World (ie, Western Hemisphere) rodents (family Muridae, subfamily Sigmodontinae). (medscape.com)
  • The likes of Joe Andruzzi, Dan Connolly, Ryan Wendell, Josh Kline and endless others were never top athletes or prospects, but they found a functional home on Dante Scarnecchia's offensive lines. (patriots.com)
  • Evidence for broader autism phenotype characteristics in parents from multiple-incidence autism families. (springer.com)
  • URW Geometric® is functional, strong, simple and harmonized in form, and at a glance appears as a modern variant of its predecessors. (linotype.com)
  • This gives Hierophant a distinctive hand-drawn feel which also reflects the strong influence of the work of 16th century calligrapher Giovanni Francesco Cresci upon this family. (fonts.com)
  • Functional constipation is often seen in children and has diseases, and various cancers (9,10) . (who.int)
  • Taps Black MC18N: Smeg designed in Italy, has functional characteristics of quality with a design that combines style and high technology. (smeg.com)
  • Population ageing is a worldwide reality that requires attention, and a concern for healthy and functional ageing is increasingly the focus of government policies and programmes. (bvsalud.org)
  • With its 95 m2 and its proximity to middle and high schools (only 200 meters), this property offers a rare opportunity for families wishing to settle in a peaceful environment while remaining close to essential amenities. (french-property.com)
  • Given the growing number of older work ers and changing work and family situations, continued monitoring of work - family experiences among older work ers is warranted. (cdc.gov)
  • Cucurbitaceae is one of the most important plant families distributed worldwide. (unl.edu)