• Within these 28 cases, 15 died of sudden cardiac arrest and 13 of acute heart failure. (nature.com)
  • Four teenagers drank alcohol before sudden cardiac arrest. (nature.com)
  • Heart failure and sudden cardiac arrest occur at various ages with inter- and intrafamilial phenotypic variability, and presentation can include progressive neurological disease. (nature.com)
  • Alcohol intake can trigger cardiac arrest and should be strictly avoided. (nature.com)
  • The spectrum of clinical presentations included sudden unexpected death in children before the age of 2 years, mitochondrial disease leading to death in infants aged between 1 month and 2 years, sudden cardiac arrest following the ingestion of small amounts of alcohol in teenagers, and adults reporting acute sensitivity to alcohol. (nature.com)
  • Ingestion of alcohol could act as a trigger by increasing the stress in heart tissue, leading to arrhythmia and cardiac arrest. (nature.com)
  • A set of clinical interventions used for the urgent treatment of cardiac arrest and other life-threatening medical emergencies as well as the knowledge and skills to deploy those interventions. (fema.gov)
  • Twenty-eight years ago, while editor of The Patriot Ledger in Quincy, Massachusetts, the paper covered the cardiac arrest death of 16-year-old Quincy High hockey player Matthew Messing. (cnhi.com)
  • Doctors reported Hamlin experienced cardiac arrest - which can be caused by concussion of the heart at the exact moment it resets normal rhythm. (cnhi.com)
  • No specific cause has been determined yet for his cardiac arrest. (cnhi.com)
  • Cardiac arrest is unusual during a game, yet training to recognize it and deal with it rapidly is required. (cnhi.com)
  • Nor other athletes who have died from cardiac arrest over the years - though, we pray, not in vain. (cnhi.com)
  • Malignant electroencephalography patterns are considered predictive of poor outcome in comatose survivors of cardiac arrest. (ajnr.org)
  • Retrospective review of clinical, imaging, and electroencephalography data of 33 adult comatose survivors of cardiac arrest following therapeutic hypothermia was performed. (ajnr.org)
  • Prognostication of survival and functional outcome in comatose survivors of cardiac arrest is challenging. (ajnr.org)
  • Understanding the relationship between these modalities may establish an evidenced-based role for MR imaging in prognostication following cardiac arrest. (ajnr.org)
  • All subjects were comatose adults 24-80 years of age admitted at a single tertiary care center following resuscitation from an in- or out-of-hospital cardiac arrest between April 14, 2010, and October 29, 2011. (ajnr.org)
  • Christopher Akers-Belcher had a cardiac arrest in January, after waking in the middle of the night with chest pains. (nth.nhs.uk)
  • citation needed] Cardiac catheterization can be used as part of a therapeutic regimen to improve outcomes for survivors of out-of-hospital cardiac arrest. (wikipedia.org)
  • This condition alters the normal beating of the heart and can lead to fainting (syncope) or sudden cardiac arrest and death. (medlineplus.gov)
  • What Happens After Someone Experiences Sudden Cardiac Arrest While Playing Sports? (clevelandclinic.org)
  • Sudden cardiac arrest occurs when the heart stops beating or is not beating sufficiently to maintain adequate blood flow and life. (clevelandclinic.org)
  • Dr. Michael Emery and Dr. Tamana Singh , Co-Directors of the Sports Cardiology Center, talk about what happens to an athlete who experiences sudden cardiac arrest and everything that happens after. (clevelandclinic.org)
  • But first, Dr. Singh, I want to start by having you tell us the difference between sudden cardiac arrest or cardiac arrest and a heart attack. (clevelandclinic.org)
  • So cardiac arrest is when the heart actually goes into an abnormal rhythm originating from the bottom chambers of the heart that can actually cause death, versus a heart attack where there's a part of the heart muscle that's not getting adequate blood supply or oxygen supply at a particular point of stress, or even when someone is just sitting and watching TV. (clevelandclinic.org)
  • So off that, we see media reports and a lot of public media attention when an athlete suffers sudden cardiac arrest. (clevelandclinic.org)
  • I think just to preface that, cardiac arrest, even outside of the athletic sphere, is actually, I don't want to say common, but not unheard of. (clevelandclinic.org)
  • When available, cardiac histology or magnetic resonance image (MRI) frequently showed evidence of myocardial fibrosis. (nature.com)
  • Cardiac resynchronization therapy improves cardiac performance and myocardial mechanical efficiency. (elsevierpure.com)
  • Cardiac tissue bioengineering represents an important research direction for the patient-specific myocardial reconstruction therapies. (romanianjournalcardiology.ro)
  • Recellularization was performed on decellularized cardiac tissue fragments and in 3 D models, throu-gh intraventricular injection or aortic perfusion with myocardial cells. (romanianjournalcardiology.ro)
  • It acts directly on cardiac muscle, increasing myocardial systolic contractions. (medscape.com)
  • This study provides important findings on the distinct functions of resident and recruited macrophages during cardiac healing after myocardial ischemia. (elifesciences.org)
  • Of this number, approximately 1 million survivors of acute myocardial infarction (MI), as well as the more than 300,000 patients who undergo coronary bypass surgery annually, are candidates for cardiac rehabilitation. (medscape.com)
  • Secondary endocardial fibroelastosis, associated with cardiac malformations, is attributed to the cardiac hypertrophy and consequent imbalance in the myocardial oxygen supply-demand relationship. (medscape.com)
  • Heart failure (HF) disease progression is related to numerous adaptive processes including cardiac fibrosis, hypertrophy and apoptosis by activation of the 'fetal' gene program and downregulation of mRNA signatures, suggesting the importance of molecular mechanisms that suppress mRNA steady-state levels. (elsevierpure.com)
  • A pathological cardiac hypertrophy model, junctate-1 transgenic mice and control mice, were analyzed using label-free quantitative phosphoproteomics to identify differentially phosphorylated proteins and sites. (molcells.org)
  • Cardiac hypertrophy can be characterized as the response of the heart to various hemodynamic stresses. (molcells.org)
  • Although cardiac hypertrophy is initiated by various receptors at cell membranes sensing biomechanical signals and hormones, it is generally mediated by cellular signaling cascades. (molcells.org)
  • In cardiac hypertrophy, phosphorylation-dependent functional modulation of proteins, especially sarcoplasmic reticulum (SR) and sarcomere proteins, has been demonstrated. (molcells.org)
  • CRT effects are related to alterations in genes and microRNAs (miRs) expression, which regulate cardiac processes involved in cardiac apoptosis, cardiac fibrosis, cardiac hypertrophy and angiogenesis, and membrane channel ionic currents. (hindawi.com)
  • The sessions are run by the cardiac rehabilitation service at North Tees and Hartlepool NHS Foundation Trust in community buildings across Stockton and Hartlepool. (nth.nhs.uk)
  • Michelle Peevor, community cardiac rehabilitation nurse, said: "Uptake nationally for these classes isn't high - but when people do come they realise how fun and rewarding it is. (nth.nhs.uk)
  • Purpose: Although ratings of perceived exertion (RPE) are widely used to guide exercise intensity in cardiac rehabilitation (CR), it is unclear whether target heart rate ranges (THRRs) can be implemented in CR programs that predominantly use RPE and what impact this has on changes in exercise capacity. (nursingcenter.com)
  • Medicare policy limits standard cardiac rehabilitation in HF to long-term patients with HF with reduced ejection fraction (HFrEF) only who have been stabilized for 6 weeks or longer after a recent hospitalization. (medscape.com)
  • And Dr. Jonathan Whiteson, who's a medical director of Cardiac and Pulmonary Rehabilitation, and codirector of NYU Post-COVID Care Program at Rusk Rehabilitation NYU Langone Health. (cdc.gov)
  • Cardiac rehabilitation aims to reverse limitations experienced by patients who have suffered the adverse pathophysiologic and psychological consequences of cardiac events. (medscape.com)
  • The image below depicts cardiac rehabilitation after bypass surgery. (medscape.com)
  • Traditionally, cardiac rehabilitation has been provided to somewhat lower-risk patients who could exercise without getting into trouble. (medscape.com)
  • Currently, about 400,000 patients who undergo coronary angioplasty each year make up a subgroup that could benefit from cardiac rehabilitation. (medscape.com)
  • Cardiac rehabilitation programs have been consistently shown to improve objective measures of exercise tolerance and psychosocial well being without increasing the risk of significant complications. (medscape.com)
  • the American Association of Cardiovascular and Pulmonary Rehabilitation (AACVPR), and the National Heart, Lung and Blood Institute (NHLBI) have recognized the wide variation in awareness and understanding of the role of cardiac rehabilitation among physicians, ancillary health care providers, third-party payers, and patients with heart disease. (medscape.com)
  • Approximately 38% of US patients and 32% of Canadian patients with acute MI who were involved in the Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries (GUSTO) trial were enrolled in cardiac rehabilitation programs. (medscape.com)
  • Therefore, the outcome measures of cardiac rehabilitation now include improvement in quality of life (QOL), such as the patient's perception of physical improvement, satisfaction with risk factor alteration, psychosocial adjustments in interpersonal roles, and potential for advancement at work commensurate with the patient's skills (rather than simply return to work). (medscape.com)
  • In this updated critical appraisal we report on the main miRs that play a key role in response to cardiac resynchronization therapy (i.e., responder vs nonresponder HF patients), focusing on the miR-mediated modulation of cardiac angiogenesis, apoptosis, fibrosis and membrane ionic currents. (elsevierpure.com)
  • A quantitative understanding of the heart function is crucial for several cardiac therapies, ranging from ablation or resynchronization therapy to valve replacement. (zib.de)
  • In selected patients affected by HF and severe dysfunction of left ventricle ejection fraction (LVEF), with left bundle brunch block, the cardiac resynchronization therapy with a defibrillator (CRT) is the treatment of choice to improve symptoms, NYHA class, and quality of life. (hindawi.com)
  • In patients under optimal medical therapy with moderate to severe HF and cardiac dyssynchrony, cardiac resynchronization therapy (CRT) with a defibrillator improves contractile function and reverse ventricular remodeling, ameliorating symptoms, quality of life (QoL), and clinical outcomes [ 7 , 8 ]. (hindawi.com)
  • Secondary outcomes included exercise HR, RPE, and changes in functional exercise capacity. (nursingcenter.com)
  • Data gathered from the PROTein to Enhance outComes of (pre)frail paTients undergoing Cardiac Surgery Study will be published in peer-reviewed journals and presented at national and international conferences. (bmj.com)
  • Hospital-acquired functional decline and clinical outcomes in older cardiac surgical patients: a multicenter prospective cohort study. (ahrq.gov)
  • The cardiac conduction system (CCS) (also called the electrical conduction system of the heart ) [1] transmits the signals generated by the sinoatrial node - the heart 's pacemaker , to cause the heart muscle to contract , and pump blood through the body's circulatory system . (wikipedia.org)
  • Embryologic evidence of generation of the cardiac conduction system illuminates the respective roles of this specialized set of cells. (wikipedia.org)
  • The exposition of cardiac conduction system during breast radiation therapy has never been studied, despite the increasing use of intensity-modulated radiation therapy, which exposes larger volume to low-dose bath. (allenpress.com)
  • With the development of cardiac conduction system delineation atlases [ 6 ], evaluating the relationship between conduction disorders or arrhythmias and conduction substructure exposure has become possible. (allenpress.com)
  • Cardiac Autonomic Function and Functional Capacity in Post-COVID-19 Individuals with Systemic Arterial Hypertension. (bvsalud.org)
  • This study assessed differences in cardiac autonomic function (CAF) and functional capacity (FC) in SAH individuals without COVID-19 infection compared to SAH individuals post-COVID-19. (bvsalud.org)
  • However, the study did not find impaired cardiac autonomic function in SAH individuals post-COVID-19 compared to those without. (bvsalud.org)
  • Moreover, the increase of overweight / obesity has been a concern in recent years due to the growing body of knowledge that links poor diet and sedentary lifestylesto the weight gain and body fat in children 11 and, moreover, implications of short and long term for health, including changes in cardiac autonomic function 12 . (bvsalud.org)
  • These protective effects may be associated with the inhibition of apoptosis and inflammation, as reflected by less TUNEL-positive cells and lower levels of serum proinflammatory cytokines (Interleukin-1β, Interleukin-6, tumor necrosis factor-α) and cardiac troponin I in the N-CM group compared with the vehicle group. (researchsquare.com)
  • In addition, Aurora use arrhythmia model assays to investigate cardiac functionality. (aurorabiomed.com)
  • Both were diagnosed as sudden unexpected death in infancy (SUDI), attributed to a possible cardiac arrhythmia. (nature.com)
  • Methods: Twenty-three patients with suspected MVA (66 ± 11 years), 19 CAD patients (69 ± 5 years) with stress-induced ischaemia and 24 healthy controls (61 ± 10 years) underwent cardiac magnetic resonance (CMR) including coronary sinus flow measurements and first-pass perfusion at rest and during adenosine stress. (lu.se)
  • At 20 days post-exposure, the animals underwent cardiac perfusion to fix their cochleae. (cdc.gov)
  • Tridimensional cardiac tissues generation requires a structural matrix, specialized cardiac cells and an optimal medium in which cells can multiply and form a mature tissue, capable of sustaining the complex cardiac functions. (romanianjournalcardiology.ro)
  • Pathological variants in TRPM4 gene have been linked to several cardiac phenotypes such as complete heart block (CHB), ventricular tachycardia, and Brugada syndrome (BrS). (frontiersin.org)
  • In conclusion, decreased or increased protein expression of several TRPM4 variants linked to cardiac conduction disorders or ventricular arrhythmias were found to be caused by altered TRPM4 half-life compared to the WT form. (frontiersin.org)
  • Gated coronary CT was introduced in the 1980s and demonstrated a wide range of pathology, including intracardiac thrombus, ventricular aneurysms and cardiac scars. (acr.org)
  • To which extent structural damage causes functional decline is unknown. (nih.gov)
  • Hypertrophic cardiomyopathy (HCM) is the most common cause of cardiac death among young people and affects one in every 500 individuals, including professional athletes. (harvard.edu)
  • Cardiac hypertrophic signaling cascades resulting in heart failure diseases are mediated by protein phosphorylation. (molcells.org)
  • A cell-based functional assay system measuring hypertrophic cell growth of neonatal rat ventricle cardiomyocytes (NRVMs) following phenylephrine treatment was applied, and changes in phosphorylation of individual differentially phosphorylated sites were induced by incorporation of phosphorylation competition peptides conjugated with cell-penetrating peptides. (molcells.org)
  • Cell-based functional screening against 18 selected phosphorylation sites identified three phosphorylation sites (Ser-98, Ser-179 of Ldb3, and Ser-1146 of palladin) displaying near-complete inhibition of cardiac hypertrophic growth of NRVMs. (molcells.org)
  • In the last 40 years, over 20% of drugs discontinued at all phases of development, including discovery, preclinical and clinical evaluation, and post-market surveillance has been due to cardiac toxicity, where unintended interactions with cardiac ion channels result in pro-arrhythmic effects 4 . (nature.com)
  • All theory and practice is designed to prepare you for your year 2 clinical placement in a cardiac department. (southampton.ac.uk)
  • These methods have drawbacks, but give invasive estimations of the cardiac output, which can be used to make clinical decisions (e.g., cardiogenic shock, heart failure) to improve the person's condition. (wikipedia.org)
  • Cardiac CT angiography slowly entered clinical practice in the early 2000s when multi-detector row CTs were developed. (acr.org)
  • Cardiac magnetic resonance (MR), both morphologic and functional, and cardiac MR angiography continue to evolve in clinical practice. (acr.org)
  • The guidelines go on to reference additional Cardiac Dimensions' studies that confirm the favorable results of the Carillon Mitral Contour System on left atrium volumes and left ventricle remodeling with trends towards improvement in clinical measures, and a reduction in heart failure hospitalizations. (cardiacdimensions.com)
  • Being the only device, other than TEER, mentioned in the 2021 ESC guidelines for the treatment of secondary mitral regurgitation is a testament to our excellent clinical data and the overwhelming need for additional treatment options in the space," said Rick Wypych, Cardiac Dimensions President and Chief Executive Officer. (cardiacdimensions.com)
  • However, functional studies of these differentially phosphorylated proteins have not been conducted in a large-scale or high-throughput manner due to a lack of methods capable of revealing the functional relevance of each phosphorylation site. (molcells.org)
  • Biallelic hypomorphic variants in PPA2 , encoding the mitochondrial inorganic pyrophosphatase 2 protein, have been recently identified in individuals presenting with sudden cardiac death, occasionally triggered by alcohol intake or a viral infection. (nature.com)
  • The role of pyrophosphatase 2 (PPA2) in mitochondrial disease has recently emerged with the discovery of biallelic PPA2 variants that cause a partial loss of gene function (hypomorphs) within families affected by recurrent sudden cardiac death in siblings. (nature.com)
  • Preventing young sudden cardiac deaths through awareness, screening and research, and supporting affected families. (c-r-y.org.uk)
  • We wanted to take some time today to discuss sudden cardiac arrests and sudden cardiac death in athletes. (clevelandclinic.org)
  • Assessment of drug-induced proarrhythmic risk and cardiac dysfunction at multiple levels is critical to modern cardiac safety screening. (aurorabiomed.com)
  • The anatomical and functional changes affect the respiratory and cardiovascular systems. (medscape.com)
  • Cardiotoxicity studies evaluating conduction node exposure might define dose constraints and criteria for additional cardiac-sparing techniques, such as respiratory techniques or proton therapy, which could benefit patients with underlying rhythmic or conduction disorders. (allenpress.com)
  • In the current study, we aimed to identify epigenetic variants associated with alterations in cardiac autonomic responses. (cdc.gov)
  • The researchers plan to test the cells in an animal model of cardiac disease, and also investigate the potential of enhancing electrical conductivity between the cells, to facilitate the cell-cell communication that occurs in the heart. (medgadget.com)
  • To obtain functional cardiac tissue on a rat animal model, starting with a decellularized heart used as a matrix for grafting the human cells- adult mesenchymal stem cells (MSC) and induced pluripotent stem cells (iPSC) obtained through peripheral blood lymphocytes T transduction. (romanianjournalcardiology.ro)
  • Our study showed that decellularization of the rat heart using the simplified Langendorff in alternative electric field is more efficient, because it used smaller amount of potentially noxious substances for the cardiac matrix. (romanianjournalcardiology.ro)
  • Both exercise-induced molecular mechanisms and physiological cardiac remodeling have been previously studied on a whole heart level. (researchgate.net)
  • The heart is a functional syncytium as opposed to a skeletal muscle syncytium . (wikipedia.org)
  • Functional Imaging and Modeling of the Heart. (zib.de)
  • Cardiac catheterization (heart cath) is the insertion of a catheter into a chamber or vessel of the heart. (wikipedia.org)
  • Cardiac catheterization often requires the use of fluoroscopy to visualize the path of the catheter as it enters the heart or as it enters the coronary arteries. (wikipedia.org)
  • Right heart catheterizations also allow the physician to estimate the cardiac output, the amount of blood that flows from the heart each minute, and the cardiac index, a hemodynamic parameter that relates the cardiac output to a patient's body size. (wikipedia.org)
  • The sodium channels containing proteins produced from the SCN5A gene are abundant in heart (cardiac) muscle cells and play key roles in these cells' ability to generate and transmit electrical signals. (medlineplus.gov)
  • Heart Month also affords an opportunity to marvel at the evolution of cardiac imaging and intervention, and the radiologists who pioneered this evolving field. (acr.org)
  • Throughout the remainder of this Heart Month, let's celebrate the grand history of cardiac imaging while also focusing on our own heart health. (acr.org)
  • KIRKLAND, WA - Sept. 22, 2021 - Cardiac Dimensions, a leader in the development of innovative, minimally invasive treatment modalities to address heart failure and related cardiovascular conditions, today announced the mention of their Carillon Mitral Contour System in the 2021 European Society of Cardiology (ESC) Guidelines for the Diagnosis and Treatment of Acute and Chronic Heart Failure. (cardiacdimensions.com)
  • Cardiac Dimensions is reimagining the solutions available to patients suffering from heart failure by providing a therapy that allows patients to live longer, higher quality lives. (cardiacdimensions.com)
  • Introduction In the past 20 years, the increasing burden of heart disease in an ageing population has resulted in cardiac surgery (CS) being offered to more frail and older patients with multiple comorbidities. (bmj.com)
  • Heart muscle cells die en masse after injury, yet the adult mammalian heart retains little capacity to regenerate them. (natureasia.com)
  • Aurora offers various functional assays to asses cardiac safety including the action potential of Purkinje fibers as an important site for the initiation of arrhythmias. (aurorabiomed.com)
  • In response, international regulatory agreements were developed that mandate testing of all new drugs, both cardiac and non-cardiac, for cardiac liability, including drug-induced long QT interval (LQT) and risk for development of life-threatening arrhythmias, such as Torsade de Pointes (TdP) 5 . (nature.com)
  • However, the physiological role for this channel in cardiac function remains unclear. (frontiersin.org)
  • It therefore remains unclear whether cardiomyocyte Kind2 expression is required for cardiomyocyte junction formation and the development of normal cardiac function. (ed.ac.uk)
  • Cardiac mitochondrial function is altered in a variety of inherited and acquired cardiovascular diseases. (jci.org)
  • This augmented adverse remodelling after I/R and led to an increased infarct size and deterioration of cardiac function. (elifesciences.org)
  • Imaging and percutaneous cardiac/coronary interventions continue to play significant roles in contemporary cardiac care management. (acr.org)
  • Current cardiac care has already reduced early acute coronary mortality so much so that further exercise training, as an "isolated" intervention, may not be able to cause significant reduction in the morbidity and mortality. (medscape.com)
  • Taken together, CITED4 expression is necessary for exercise-induced regional remodeling of the heart's microstructural helicity revealing how a key molecular regulator of cardiac remodeling manifests into downstream local tissue-level changes. (researchgate.net)
  • Expression of transcription factor CITED4 is necessary for exercise-induced regional remodeling of the heart's microstructural helicity, revealing how a key molecular regulator of cardiac remodeling mediates local tissue-level changes. (researchgate.net)
  • Other mutations prevent the SCN5A gene from producing any functional ion channels, which also reduces the inward flow of sodium ions. (medlineplus.gov)
  • Several functional studies have reported that the Ahl gene renders mice more susceptible to noise -induced hearing loss (NIHL) than strains which do not carry this gene [e.g. (cdc.gov)
  • Kurt Amplatz developed power injectors and later developed devices for percutaneous repair of congenital cardiac defects. (acr.org)
  • Therapeutic cardiac interventions, particularly coronary artery interventions, became possible because of the pioneering work of Charles Dotter (angioplasty) and Melvin Judkins (angiography), with Andreas Gruentzig subsequently performing the first coronary balloon angioplasty in the late 1970s. (acr.org)
  • AVOW, a nonprofit , has a new cardiac care initiative that provides patients with the opportunity to get care in their homes. (abc-7.com)
  • Limited research has examined inspiratory muscle performance (IMP) and functional performance (FP) of patients after valve replacement surgery (VRS). (ljmu.ac.uk)
  • In fact, in the Multicenter Automatic Defibrillator Implantation Trial with CRT (MADIT-CRT) and the Cardiac Resynchronization-HF (CARE-HF), the mean age of enrolled patients was 65 and 66.4, respectively [ 11 , 12 ]. (hindawi.com)
  • The identification of the patients at risk for a cardiac event's recurrence (ie, risk stratification) is central to formulating an appropriate medical, rehabilitative, and surgical strategy to prevent such a recurrence. (medscape.com)
  • Silencing both Fit1 and Fit2 led to a severe cardiomyopathy characterised by the failure of cardiomyocytes to develop as a functional syncytium and loss of synchrony between cardiomyocytes. (ed.ac.uk)
  • Researchers at Michigan Tech and Harvard Medical School have developed a new way to create cardiomyocytes from induced pluripotent stem cells (iPSCs), for improved cardiac cell therapy. (medgadget.com)
  • These mutations alter the structure of ion channels made with the SCN5A protein and disrupt the flow of sodium ions into cardiac muscle cells. (medlineplus.gov)
  • We have been a leader in creating user-centric and functional business & marketing solutions ever since 2000. (dotcominfoway.com)
  • Adequate visual, motor, and cognitive abilities are needed to drive safely and require functional assessment to identify deficits. (msdmanuals.com)
  • The project aims at developing numerical software able to simulate cardiac excitation with a cellular resolution at organ scale on advanced HPC exascale systems. (zib.de)
  • The data definitively demonstrate a role for Fermitins in the development of a functional cardiac syncytium in Drosophila. (ed.ac.uk)
  • In a functional syncytium, electrical impulses propagate freely between cells in every direction, so that the myocardium functions as a single contractile unit. (wikipedia.org)
  • Despite recent findings regarding the functional implications of TRPM4 in cardiac diseases, the molecular and cellular mechanisms leading to altered conduction are poorly understood. (frontiersin.org)
  • In this study, an integrated approach combining quantitative phosphoproteomics and cell-based functional screening using phosphorylation competition peptides was developed. (molcells.org)
  • Explain the principles of a range of routine non-invasive diagnostic cardiac investigations used to detect and quantify cardiac disease, and compare and contrast each modality. (southampton.ac.uk)
  • Interventions With the Older Driver If older drivers with significant functional deficits decide to limit or stop driving, the role of health care practitioners is largely supportive. (msdmanuals.com)
  • RPE (average score 3.0 +/- 0.05) was unchanged, and functional exercise capacity increased by 1.0 +/- 1.0, 1.9 +/- 1.5, 2.0 +/- 1.3 workload METs (effect size between groups, [eta] p 2 = 0.11, P = .20) for the RPE, THRR, and THRR + HRM groups, respectively. (nursingcenter.com)
  • Impact of exercise program on functional status among post lumbar laminectom. (slideshare.net)