Aspergillus fumigatus is a species of fungus in the genus Aspergillus, and is one of the most common Aspergillus species to cause disease in individuals with an immunodeficiency. (wikipedia.org)
Aspergillus fumigatus, a saprotroph widespread in nature, is typically found in soil and decaying organic matter, such as compost heaps, where it plays an essential role in carbon and nitrogen recycling. (wikipedia.org)
Aspergillus fumigatus grown on certain building materials can produce genotoxic and cytotoxic mycotoxins, such as gliotoxin. (wikipedia.org)
Aspergillus fumigatus has a stable haploid genome of 29.4 million base pairs. (wikipedia.org)
Aspergillus fumigatus is the most frequent cause of invasive fungal infection in immunosuppressed individuals, which include patients receiving immunosuppressive therapy for autoimmune or neoplastic disease, organ transplant recipients, and AIDS patients. (wikipedia.org)
Minimum spanning tree comparing genotypic relatedness of clinical azole- resistant Aspergillusfumigatus isolates carrying TR34/L98H alteration in the CYP 51A gene from Iran with those reported from European countries. (cdc.gov)
Emergence of azole resistance in Aspergillusfumigatus and spread of a single resistance mechanism. (cdc.gov)
Frequency and evolution of azole resistance in Aspergillusfumigatus associated with treatment failure. (cdc.gov)
3. Mellado E, De La Camara R, Buendia B, Rodriguez-Tudela JL, Cuenca-Estrella M. Breakthrough pulmonary Aspergillusfumigatus infection with multiple triazole resistance in a Spanish patient with chronic myeloid leukemia. (cdc.gov)
Aspergillus species and other molds in respiratory samples from patients with cystic fibrosis: a laboratory-based study with focus on Aspergillusfumigatus azole resistance. (cdc.gov)
Triazole resistance among clinical Aspergillusfumigatus isolates. (cdc.gov)
High prevalence of azole-resistant Aspergillusfumigatus in adults with cystic fibrosis exposed to itraconazole. (cdc.gov)
High prevalence of triazole resistance in Aspergillusfumigatus , especially mediated by TR/L98H, in a French cohort of patients with cystic fibrosis. (cdc.gov)
Aspergillus fumigatus due to the TR/L98H mutation in Germany. (cdc.gov)
Clonal expansion and Emergence of eEnvironmental multiple-triazole-resistant Aspergillusfumigatus strains carrying the TR(34)/L98H mutations in the cyp51A gene in India. (cdc.gov)
Azole resistance in Aspergillusfumigatus isolates from the ARTEMIS global surveillance study is primarily due to the TR/L98H mutation in the cyp51A gene. (cdc.gov)
Patients with high titres of antibodies to Aspergillusfumigatus were significantly more likely to live in an area of low population density. (nih.gov)
In Aspergillusfumigatus , iron starvation causes extensive transcriptional remodeling involving two central transcription factors, which are interconnected in a negative transcriptional feed-back loop: the GATA-factor SreA and the bZip-factor HapX. (frontiersin.org)
Aspergillus fumigatus is a ubiquitous saprophytic fungus, which has become the most common air-borne fungal pathogen of humans ( Tekaia and Latge, 2005 ). (frontiersin.org)
The present study aims at the production optimization, purification, and characterization of a potent broad-spectrum antimicrobial compound (AMC) produced by Aspergillusfumigatus nHF-01 (GenBank Ac. (nature.com)
Ecology of aspergillosis: insights into the pathogenic potency of Aspergillusfumigatus and some other Aspergillus species. (jcvi.org)
Some Aspergillus species, most commonly Aspergillusfumigatus, may lead to a variety of allergic reactions and life-threatening systemic infections in humans. (jcvi.org)
Screening of cellulolytic activity by ten fungal isolates recovered from soil and agricultural wastes indicated that Aspergillusfumigatus showed the highest cellulolytic activity, under solid-state fermentation (SSF) using rice straw as substrate. (scialert.net)
abstract = "Aspergillus fumigatus is the most pathogenic species among the Aspergilli, and the major fungal agent of human pulmonary infection. (manchester.ac.uk)
200). Although bioaerosols can be generated through a range of operational procedures it has also been suggested that large numbers of Aspergillusfumigatus spores can be emitted from static compost piles through the action of natural air movements across the surface of the biodegrading material. (whiterose.ac.uk)
Through the use of a portable wind tunnel apparatus researchers have determined the rate of emission of Aspergillusfumigatus spores as a result of air movement across the surface of the material (Taha et al. (whiterose.ac.uk)
The aim of this work was to use controlled laboratory experiments using compost samples and Aspergillusfumigatus spores to determine the sporulation rate of Aspergillusfumigatus. (whiterose.ac.uk)
A series of experiments were carried out using Aspergillusfumigatus spores on agar plates and small samples of green waste compost to determine the number of spores that could be generated by each existing spore over a seven day period. (whiterose.ac.uk)
Although the data presented in this paper were determined from controlled laboratory experiments they show that it is possible for Aspergillusfumigatus to generate spores at a sufficient rate to allow the release of significant numbers of spores. (whiterose.ac.uk)
However it is recognised that the data is affected greatly by the assumptions one makes, in particular the existing concentration of Aspergillusfumigatus. (whiterose.ac.uk)
Despite the limitations the original intention of the work was to attempt to establish the long term applicability of the fugitive release rates for Aspergillusfumigatus from green waste compost quoted in the literature and it has achieved this objective. (whiterose.ac.uk)
Aspergillus fumigatus causes severe problems in poultry production systems. (up.ac.za)
Learn how to control AspergillusFumigatus with these easy to use products! (domyown.com)
Pulmonary infections caused by the mould pathogen Aspergillusfumigatus are a major cause of morbidity and mortality globally. (manchester.ac.uk)
The filamentous fungus Aspergillusfumigatus can cause a distinct set of clinical disorders in humans. (bath.ac.uk)
The genome sequence and gene predictions of Aspergillusfumigatus A1163 were not determined by the JGI, but were downloaded from ENSEMBL and have been published ( Natalie D. Fedorova (2008) , William C. Nierman (2005) , Catherine M. Ronning (2005) ). (doe.gov)
Aspergillus fumigatus is exceptional among microorganisms in being both a primary and opportunistic pathogen as well as a major allergen. (doe.gov)
Genomic islands in the pathogenic filamentous fungus Aspergillusfumigatus. (doe.gov)
Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillusfumigatus. (doe.gov)
As part of studies on the spread of infections, risk factors and prevention, several typing methods were developed to investigate the epidemiology of Aspergillusfumigatus. (elsevierpure.com)
O:13:\"PanistOpenUrl\":36:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000idc\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:0:\"\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:71:\"OCCURRENCE OF ASPERGILLUSFUMIGATUS DURING COMPOSTING OF SEWAGE SLUDGE. (inist.fr)
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Aspergillus fumigatus is a saprotrophic filamentous fungus and also the most prevalent airborne fungal pathogen of humans. (leibniz-hki.de)
Aspergillus fumigatus during stable state and exacerbations of COPD. (ox.ac.uk)
We investigated the frequency of filamentous fungal culture and IgE sensitisation to Aspergillusfumigatus and the relationship to clinical outcomes in COPD subjects. (ox.ac.uk)
Title : Pulmonary immune responses to Aspergillusfumigatus in an immunocompetent mouse model of repeated exposures Personal Author(s) : Buskirk, Amanda D.;Templeton, Steven P.;Nayak, Ajay P.;Hettick, Justin M.;Law, Brandon F.;Green, Brett J.;Beezhold, Donald H. (cdc.gov)
One patient, the index case, had a laboratory-confirmed Aspergillusfumigatus image icon infection. (cdc.gov)
Reducing the Unintentional Impact of Triazole Fungicides on Aspergillus fumigatus: Are Cyclodextrins a Solution? (fortunejournals.com)
However, their spread in the environment can lead to the selection of triazole resistance not only in crop pathogens, but also in non-target organisms, such as a non-phytopathogenic fungus Aspergillusfumigatus. (fortunejournals.com)
During this period, these fungicides may have unintended effects on Aspergillusfumigatus , a non-phytopathogenic fungus naturally present in soils, through the exertion of selection pressure [10]. (fortunejournals.com)
Osteomyelitis and lung abscess due to Aspergillusfumigatus in a chronic granulomatous disease patient', Current Medical Mycology , 2(3), pp. 37-41. (ac.ir)
Aspergillus fumigatus is a human fungal pathogen that causes aspergillosis in immunocompromised hosts. (biomedcentral.com)
Filamentous fungus Aspergillusfumigatus is a ubiquitous fungus commonly found in soil, but is also reported as a major cause of invasive fungal aspergillosis infections in humans, especially in patients with compromised or suppressed host immunity [ 2 , 3 , 4 ]. (biomedcentral.com)
Completion of the sequence of the Aspergillusfumigatus partitivirus 1 genome. (herts.ac.uk)
A Portuguese isolate of Aspergillusfumigatus was found to contain three double-stranded (ds) RNA elements ranging in size from 1.1 to 1.8 kbp and comprising the genome of a strain of Aspergillusfumigatus partitivirus 1 (AfuPV-1) previously thought to contain only the two largest dsRNA elements. (herts.ac.uk)
Dive into the research topics of 'Completion of the sequence of the Aspergillusfumigatus partitivirus 1 genome. (herts.ac.uk)
Deciphering the counterplay of Aspergillusfumigatus infection and host inflammation by evolutionary games on graphs. (leibniz-hki.de)
Pollmächer J, Timme S, Schuster S, Brakhage AA, Zipfel PF, Figge MT (2016) Deciphering the counterplay of Aspergillusfumigatus infection and host inflammation by evolutionary games on graphs. (leibniz-hki.de)
To investigate the counterplay of infection and inflammation, we simulated the invasion of the human-pathogenic fungus Aspergillusfumigatus in lung alveoli by evolutionary games on graphs. (leibniz-hki.de)
Nucleotide sequence of a genomic and a cDNA clone encoding an extracellular alkaline protease of Aspergillusfumigatus. (unil.ch)
Aspergillus fumigatus was isolated from 5 birds with characteristic lesions of airsacculitis. (cdc.gov)
Factors contributing to sex differences in mice inhaling Aspergillusfumigatus. (cdc.gov)
Fatal Fungicide-Associated Triazole-Resistant A fumigatus An older, immunocompromised patient presented with a case of triazole-resistant Aspergillusfumigatus infection that was linked to agricultural fungicide use. (medscape.com)
Additionally, A. fumigatus can cause chronic pulmonary infections, allergic bronchopulmonary aspergillosis, or allergic disease in immunocompetent hosts. (wikipedia.org)
The fungus and its polysaccharides have ability to regulate the functions of dendritic cells by Wnt-β-Catenin signaling pathway to induce PD-L1 and to promote regulatory T cell responses Immunosuppressed individuals are susceptible to invasive A. fumigatus infection, which most commonly manifests as invasive pulmonary aspergillosis. (wikipedia.org)
Deficiency in HapX, but not SreA, attenuates virulence of A. fumigatus in a murine model of aspergillosis, which underlines the crucial role of adaptation to iron limitation in virulence. (frontiersin.org)
For all the phosphomutants, there is an increase in the sensitivity to cell wall-damaging agents and a reduction in the MpkA phosphorylation upon CR stress, suggesting these phosphosites could be important for the MpkA modulation and CWI pathway regulation.IMPORTANCEAspergillus fumigatus is an opportunistic human pathogen causing allergic reactions or systemic infections, such as invasive pulmonary aspergillosis in immunocompromised patients. (bath.ac.uk)
In the present study, 52 clinical isolates of A. fumigatus from 12 airway specimens from patients with invasive aspergillosis (hospitalized in three different centres) were characterized by short tandem repeat (STR) typing and multilocus sequence typing (MLST). (elsevierpure.com)
Infection7
A. fumigatus primarily causes invasive infection in the lung and represents a major cause of morbidity and mortality in these individuals. (wikipedia.org)
However, in healthy individuals, the innate immune system is an efficacious barrier to A. fumigatus infection. (wikipedia.org)
Given the dependency of A. fumigatus upon stress adaptation for colonization and infection of mammalian hosts, and the merits of targeting receptor-mediated signaling as an antifungal strategy, a closer scrutiny of sensory perception and signal transduction in this organism is warranted. (manchester.ac.uk)
These results highlight the importance of PkcA to the CWI pathway but also indicated that additional regulatory circuits may be involved in the biosynthesis and/or reinforcement of the A. fumigatuscell wall during infection. (fapesp.br)
In contrast to the majority of other Aspergillus species, which are in most cases nonpathogenic, A. fumigatus features an armory of virulence determinants to establish an infection. (leibniz-hki.de)
We also discuss the potential impact of recent advances in immunoproteomics to improve diagnosis and therapy of an A. fumigatus infection. (leibniz-hki.de)
When A. fumigatus establishes an infection in the human lung, the mycelia must respond to highly variable conditions, which might impose stress on the fungal pathogen [ 4 , 5 ]. (biomedcentral.com)
Fungus1
Fungus was cultured in three out of 22 controls (two were A. fumigatus). (ox.ac.uk)
Opportunistic1
In this study, homologs of each of these proteins have been identified in the opportunistic human pathogen A. fumigatus. (ku.edu)
Fungi3
The antibacterial and antifungal activities of hexane, dichloromethane, acetone and methanol extracts of the leaves were determined using a two-fold serial microdilution method against a range of commonly encountered animal pathogenic fungi (A. fumigatus, Candida albicans, C. neoformans, Microsporum canis and Sporothrix schenckii) and four nosocomial bacteria (Staphylococcus aureus, Enterococcus faecalis, Escherichia coli and Pseudomonas aeruginosa). (up.ac.za)
The interaction of A. fumigatus and other airborne fungi with the immune system is increasingly linked to severe asthma and sinusitis. (doe.gov)
Filamentous fungi were cultured at baseline in 49% (63 out of 128) of COPD subjects, of which 75% (47 out of 63) were A. fumigatus. (ox.ac.uk)
It had cytotoxicity against human lung carcinoma A549 cell line and was stable up to 100 °C. Thus, the study revealed that the strain A. fumigatus nHF-01 produces a potent broad-spectrum AMC 5-butyl-2-pyridine carboxylic acid that could be used against human food and topical pathogenic bacteria. (nature.com)
Genome1
The genome mining of secondary metabolites produced by A. fumigatus , A. nidulans , A. niger , and A. terreus revealed unique biosynthetic gene clusters and biosynthetic pathways 9 . (nature.com)
20231
Downloaded from http://datazone.birdlife.org/species/factsheet/smoky-bush-tyrant-myiotheretes-fumigatus on 07/12/2023. (birdlife.org)
Nidulans2
The identification and functional characterization of 24 genes that are involved in iron homeostasis in A. fumigatus and/or Aspergillus nidulans , respectively, revealed significant insights into iron metabolism and its regulation (Table 1 ). (frontiersin.org)
A. nidulans is a less virulent A. fumigatus relative and longstanding genetic model organism. (frontiersin.org)
Pathogenicity2
In this review we highlight the progress made in characterizing receptor-mediated environmental adaptation in A. fumigatus and its relevance for pathogenicity in mammals. (manchester.ac.uk)
Thus, the adaptation mechanism in mycelia plays an important role in terms of pathogenicity of A. fumigatus . (biomedcentral.com)
Isolate1
L. alata was selected for further work to isolate compounds active against A. fumigatus and other fungal pathogens. (up.ac.za)
Strains1
We describe here the impact of linear (maltodextrin) or cyclic (cyclodextrins, CDs) dextrins and their interaction with two fungicides (difenoconazole and tebuconazole), through measurements of growth in 20 A. fumigatus strains. (fortunejournals.com)
Immunocompetent1
Depending on the host's immune status, the variety of diseases caused by A. fumigatus ranges from allergies in immunocompetent hosts to life-threatening invasive infections in patients with impaired immunity. (leibniz-hki.de)
Invasive1
Although the burden of invasive disease caused by A. fumigatus is substantial, the basic biology of the organism is mostly obscure. (doe.gov)
Pathway1
fumigatus and high-osmolarity glycerol (HOG) pathway MAPK mutants upon cell wall damage. (bath.ac.uk)
Genes1
The time series transcriptome analysis revealed the stress-responsive genes underlying the adaptation mechanisms in A. fumigatus mycelia. (biomedcentral.com)
Compost1
A. fumigatus is isolated from human habitats and vegetable compost heaps. (doe.gov)
Fermentation1
When the fermentation broth of A. fumigatus was screened, a number of indolic alkaloids with antimitotic properties were discovered. (wikipedia.org)
Lung function1
A. fumigatus sensitisation is related to poor lung function. (ox.ac.uk)
Immune1
This chapter summarizes the different strategies of A. fumigatus to manipulate the immune response. (leibniz-hki.de)
Mechanisms1
In A. fumigatus this signaling cascade is partially characterized, but the mechanisms by which it is activated are not fully elucidated. (fapesp.br)
Regulatory1
Subsequently, we constructed and analyzed a non-essential A. fumigatus pkcAG579R mutant, carrying a Gly579Arg substitution in the PkcA C1B regulatory domain. (fapesp.br)
Exposure1
With the aid of RNA-seq, we explored the global gene expression profiles of mycelia in A. fumigatus upon exposure to diverse environmental changes, including heat, superoxide, and osmotic stresses. (biomedcentral.com)
Adaptation1
To gain insights into the adaptation to environmental stresses in A. fumigatus mycelia, we conducted time series transcriptome analyses. (biomedcentral.com)
Human1
For example, A. fumigatus is able to evade the human complement system by binding or degrading complement regulators. (leibniz-hki.de)
Stress1
Here, an evaluation of the global A. fumigatus phosphoproteome under cell wall stress caused by the cell wall-damaging agent Congo red (CR) revealed 485 proteins potentially involved in the cell wall damage response. (bath.ac.uk)
Patients1
Ces allergènes devraient être placés en tête de liste des priorités lors de l'information des patients souffrant de rhinite allergique à Amman au sujet des stratégies d'évitement. (who.int)