• Our laboratory and collaborators demonstrated that cholera toxin B pentamer (CTB) and a norbornyl polymer randomly displaying galactose and fucose self-assemble into cross- linked CTBn-glycopolymer networks. (hhs.gov)
  • They were all identified as arabinoxylans with a constant A/X ratio of 0.24, but varying in their galactose and fucose residues in the side chains. (hal.science)
  • Fucoidan found in Fucucvesicuclosus is a compound consists primarily of L-fucose and sulfate along with small quantities of D-galactose, D-manose, D-xylose and uronic acid. (rroij.com)
  • Le Vivant repose pour son fonctionnement sur les propriétés structurales et fonctionnelles de grandes familles de biopolymères, parmi lesquelles celle des polysaccharides qui reste encore mal connue, et en particulier ceux exposés à la surface cellulaire ou constituant des glyco-conjugués avec les protéines. (hal.science)
  • Fucose-containing sulfated polysaccharides from brown seaweeds inhibit proliferation of melanoma cells and induce apoptosis by activation of caspase-3 in vitro. (ac.ir)
  • Using the monoclonal antibody rituximab as a model therapeutic protein, a uniform Gal2GlcNAc2Man3GlcNAc2 (A2G2) glycoform without α-1,6-fucose, plant-specific α-1,3-fucose or β-1,2-xylose residues was produced. (umd.edu)
  • We have described unique polymers present in these organisms, especially sulfated fucose-rich compounds found in the egg jelly coat of sea urchins. (embrapa.br)
  • The effect of this polymer on adhesion properties with specific extracellular matrix components was studied using several matrix proteins as substrates for cell attachment. (embrapa.br)
  • Taking advantage of two mutant endoglycosidases (EndoF3-D165A and EndoCC-N180H), which efficiently and specifically recognize core fucose and O -GlcNAc, glycopeptides can be labeled using a biantennary N -glycan probe bearing azido and oxazoline groups. (mcw.edu)
  • It is thought that much protein interaction with heparin is not direct, and instead heparin binding protein actually interact with glycosaminoglycan (GAG) side chains or mucins bound to the heparin polymer, so it is possible that heparinoids interact with these proteins in a similar way, acquiring GAG side chains in vivo. (wikipedia.org)
  • High molecular weight refers to the measurement of the size of a molecule or a polymer, typically measured in daltons (Da) or g/mol. (fucoxanthin.us)
  • A molecule or polymer with a high molecular weight is one that has a large number of atoms or monomers linked together, resulting in a larger overall size. (fucoxanthin.us)
  • There is no internationally accepted molecular standard for the composition of heparin, as it is a complex polymer of GAG units and uronic acids (including D-glucuronic acid, L-iduronic acid, and D-glucosamine). (wikipedia.org)
  • Obviously, the choice of extraction methods has a significant impact on the composition of the obtained polymer preparation, and subsequently its functional features and further applications. (medicdebate.org)
  • The structural characteristics and composition of a pectin polymer greatly contribute to its biological activity. (medicdebate.org)
  • After fractionation by size-exclusion chromatography, the analyse of the neutral monosaccharides composition showed a mixture of three major families of polymers. (hal.science)
  • Polymers with different backbones, sugar densities, and sugars will be utilized to reduce cooperativity in the inhibition arm and to analyze which are best for activation of human AE. (hhs.gov)
  • Our laboratory will interrogate and/or block function in biological systems with functionalized polymers based on recent developments from our laboratory that provide insights into how to control binding and activation of receptors, and into control of ruthenium-catalyzed metathesis copolymerizations. (hhs.gov)
  • The emulsifying dispersant is prepared from the following components by weight percent: 1% to 3% of high-molecular polymer wax inhibitor, 13% to 25% of organic aromatic solvent, 1% to 3.5% of emulsifying agent, 8% to 12% of sulfonate, 10% to 12.5% of alcohol, 10% to 20% of demulsifier and 25% to 35% of water. (patsnap.com)
  • The focus of the Renewable Products Technology Research Unit at the NCAUR (Peoria, IL) is to develop new technologies for converting renewable agricultural materials into high value chemicals, enzymes, and polymers. (mwbioprocessing.com)
  • Jorpes discovered the structure of the heparin polysaccharide in 1935, identifying that it is a highly sulfated polymer of glycosaminoglycoglycan (GAG) and uronic acid. (wikipedia.org)
  • The underlying chemical synthetic methodologies proposed for these three discrete projects are highly related through polymer synthesis. (hhs.gov)
  • Synthesis of different fucose/galactose polymer systems, analysis of the dependence of aggregation capture and kinetics on polymer structure, in combination with toxicity testing will be undertaken to develop simple, oral therapeutics for cholera disease. (hhs.gov)
  • The A monomer substituent and the microsequence of the polymer define surface behavior and solution structure morphologies. (hhs.gov)
  • Addition of polyphosphates restored defective plasma clotting of Hermansky-Pudlak syndrome patients, indicating that the inorganic polymer is the endogenous factor XII activator in vivo. (wikidoc.org)
  • L'équipe travaille à la fois sur la conception de lectines artificielles que d'inhibiteurs dérivés de sucres afin de les utiliser en tant qu'outils pour cntribuer à la compréhension de processus biologiques que pour des applications en santé (diagnostic, anti-infectieux, anti-cancéreux). (univ-nantes.fr)
  • Fucoidan is a polymer composed of sulfated L-fucose. (wikipedia.org)
  • Về cấu trúc hóa học thì fucoidan là chuỗi cao phân tử polysaccharide polymer có thành phần chủ yếu là đường fucose sulfate, ngoài ra fucoidan còn có galatose, manose, xylose và acid uronic. (secretsoflife.com)
  • Fucoidan is naturally a high molecular weight polymer, which results in a low absorption rate when digested. (fucoxanthin.us)
  • Over 50% of the polymer in Fucoidan products that are not low molecular weight is excreted without being absorbed. (fucoxanthin.us)
  • A large part of the carbohydrate losses is due to the end-wise degradation (peeling) of the carbohydrate polymers beginning at the reducing end-groups of the chains ( Sjöström 1977 ). (degruyter.com)
  • It recognizes sugars terminating in D -mannose, L -fucose or N -acetyl glucosamine present on pathogens. (medscape.com)
  • Le rôle des polysaccharides exocellulaires dans la fabrication des laits fermentés, et en particulier du yaourt, n'est plus à démontrer. (dairy-journal.org)
  • Jorpes discovered the structure of the heparin polysaccharide in 1935, identifying that it is a highly sulfated polymer of glycosaminoglycoglycan (GAG) and uronic acid. (wikipedia.org)
  • It is thought that much protein interaction with heparin is not direct, and instead heparin binding protein actually interact with glycosaminoglycan (GAG) side chains or mucins bound to the heparin polymer, so it is possible that heparinoids interact with these proteins in a similar way, acquiring GAG side chains in vivo. (wikipedia.org)
  • Mucins are large gel-forming polymers inside the mucus barrier that inhibit the yeast-to-hyphal transition of Candida albicans, a key virulence trait of this important human fungal pathogen. (nih.gov)
  • En effet, les conditions de culture (température, durée d'incubation) et la composition du milieu (source d'azote et de carbone) ont une influence considérable sur la production des EPS et leur composition en monosaccharides. (dairy-journal.org)
  • The cross-linkers in the polymer network are formulated by covalent bonds, hydrogen binding, van der Waals interactions, or by physical entanglements [ 6 ] . (encyclopedia.pub)
  • There is no internationally accepted molecular standard for the composition of heparin, as it is a complex polymer of GAG units and uronic acids (including D-glucuronic acid, L-iduronic acid, and D-glucosamine). (wikipedia.org)
  • Small amounts of fucose and rhamnose have also been found. (dairy-journal.org)
  • Although all plant cell walls contain the same general types of polymers, the specific amounts of the different polymers and their unique glycosyl residue content and linkages vary in different types of plants (e.g., woody versus herbaceous dicots versus grasses) and in different tissues and cell types. (biomedcentral.com)
  • Concentration Dependence of the Viscosity of Dilute Polymer Solutions: Huggins and Schulz‐Blaschke Constants. (iitm.ac.in)
  • Furthermore, the hydrogel system becomes more solid and insoluble in any solvent, once its polymer chains are cross-linked [ 7 ] . (encyclopedia.pub)
  • It is theorized that this change in efficacy is related to the absence of L-induronic acid, which affects the flexibility of the polymer chain. (wikipedia.org)
  • The synthesis and application of glycopeptide libraries to study the roles of fucose and sialic acid modifications in protein binding events will further be presented. (beilstein-institut.de)
  • Since the different cell wall polymers have unique physical-chemical properties, their suitability as a resource for specific bioproducts also varies, underscoring the need for cell wall analysis methods that can detect critical differences in different biomass sources. (biomedcentral.com)
  • Progress in Polymer Science 98: 101147 (* co-corresponding authors). (buffalo.edu)
  • Taking advantage of two mutant endoglycosidases (EndoF3-D165A and EndoCC-N180H), which efficiently and specifically recognize core fucose and O -GlcNAc, glycopeptides can be labeled using a biantennary N -glycan probe bearing azido and oxazoline groups. (mcw.edu)
  • The choice of plant species for production of specific bioproducts is influenced by the quality and quantity of the cell wall polymers [ 7 ]. (biomedcentral.com)
  • PLNP have a bright fluorescence in the rodamine channel, a unique property specific to this type of polymer backbone, making the particles easy to visualize in tissue sections. (env-approx.org)
  • Then, a temperature-sensitive poly( N -isopropylacrylamide) polymer functionalized with dibenzocyclooctyne was introduced to facilitate the enrichment of the labeled glycopeptides from the complex mixture. (mcw.edu)