• She has worked with the Rister Lab on two projects that examine the Drosophila (fruit fly) eye, which have possible applications for treating human diseases. (umb.edu)
  • We have used Drosophila melanogaster (a.k.a, fruit fly) eye as our model organ as 75% of genetic machinery is conserved between fruit flies and humans and have identified defective proventriculus (dve, a Homeobox gene), an ortholog of SATB-homeobox-1 (special AT-rich sequence binding protein-1 in humans), as a new member of DV- patterning genes hierarchy. (udayton.edu)
  • Another focus of this study is to employ Drosophila eye model to study Amyotrophic Lateral Sclerosis (ALS), a neurodegenerative disorder characterized by loss of upper and lower motor neurons in central nervous system with no known cure to-date. (udayton.edu)
  • Mutations in genes like human-Fused in Sarcoma (h-FUS) or cabeza (caz) in Drosophila, have been known to cause ALS in flies. (udayton.edu)
  • Misexpression of h-FUS-WT (Wild-Type), or FUS mutants FUS-R518K or FUS-R521C in Drosophila eye using GAL4-UAS genetic tool, triggers ALS-mediated neurodegeneration. (udayton.edu)
  • Characterization, bioinformatic analysis and dithiocarbamate inhibition studies of two new α-carbonic anhydrases, CAH1 and CAH2, from the fruit fly Drosophila melanogaster. (unifi.it)
  • Characterization, bioinformatic analysis and dithiocarbamate inhibition studies of two new α-carbonic anhydrases, CAH1 and CAH2, from the fruit fly Drosophila melanogaster / L. Syrjänen;M. E. E;M. Hilvo;D. Vullo;F. Carta;C. T. Supuran;S. Parkkila. (unifi.it)
  • Our ongoing project explores the genetic variation underlying Drosophila susceptibility to severe eye cell degeneration caused by human Aβ and tau. (uw.edu)
  • We express Aβ and tau in the fly eye through the UAS-GAL4 system to create our AD model Drosophila, and cross them with a panel of flies (the Drosophila Genome Reference Panel, DGRP) that allows us to map natural genetic variation for resistance to Aβ and tau. (uw.edu)
  • More specifically, we used a mutant line of Drosophila melanogaster , which we call R32, in which human transgenes of Aβ1-42 and tau are expressed in the fly eye. (uw.edu)
  • We used this reagent to express AD proteins in the Drosophila Genome Reference Panel (DGRP), a set of 200 fully sequenced, inbred lines derived from a wild population, in order to simulate a model of natural genetic variation. (uw.edu)
  • In this project, I aimed to understand how the APC/C coordinates the cell cycle with the cell specialisation process using the fruit fly, Drosophila melanogaster, as a model organism. (europa.eu)
  • During the natural developmental process of Drosophila, the developing eye shows a remarkable, tight coordination between cell proliferation and the steps for cell specialisation. (europa.eu)
  • Using the fruit fly model organism (Drosophila melanogaster), the researcher investigates how genes are regulated during the embryonic development of the nervous system. (mdc-berlin.de)
  • The fruit fly, Drosophila melanogaster, is a powerful model system for applying molecular, cellular, and genetic approaches to understanding human tauopathies, including Alzheimer's disease. (cmich.edu)
  • Here, we provide an introduction to using Drosophila as a tauopathy model system and describe several protocols that we use to analyze human tau protein expressed in flies. (cmich.edu)
  • The Drosophila protein Crumbs (Crb) helps polarize epithelial cells, boosting the amount of membrane with apical characteristics. (silverchair.com)
  • By analyzing lethal mutations in the fruit fly Drosophila Hadorn accumulated evidence that genes control development to a large extent and that they determine the body plan in great detail. (balzan.org)
  • Imaginal discs are the primordia of the Drosophila larva, which during metamorphosis give rise to the various parts of the adult fruit fly. (balzan.org)
  • This study shows that Schip1 , a Drosophila homolog of the mammalian Schwannomin interacting protein 1 (SCHIP1), provides a link between Ex and Hpo. (sdbonline.org)
  • How fast a circular patch of photoreceptor cells can evolve into a fully functional vertebrate eye has been estimated based on rates of mutation, relative advantage to the organism, and natural selection. (wikipedia.org)
  • Even with these pessimistic values, the vertebrate eye could still evolve from a patch of photoreceptor cells in less than 364,000 years. (wikipedia.org)
  • She was nominated for the prestigious Barry Goldwater Scholarship for her research identifying novel proteins that slow down the deterioration of photoreceptor cells and novel proteins that serve as tumor suppressors, which could improve our understanding of human cancers. (umb.edu)
  • We assess the "beads on a string" vs. the "specific quaternary structure" model for InaD, a scaffolding protein found in the photoreceptor cells of fruit flies, by analyzing the characteristics of the light response in flies expressing two InaD constructs where the order of the PDZ domains has been shuffled. (tdl.org)
  • The researchers also showed that Crb shields photoreceptor cells in the fly eye. (silverchair.com)
  • Sammane's research focused on light adaptation in the eye, exploring how photoreceptor cells - rods, cones, and intrinsically photosensitive retinal ganglion cells - contribute to dopamine synthesis in the retina. (rochestermedia.com)
  • Mutations in the genes that codes for presenilin lead to misprocessing of Notch and APP so that the resulting proteins either cannot do their assigned jobs properly or actively damage cells. (sciencedaily.com)
  • The team used gene editing to dial down the use of around 300 low-scoring genes found in both humans and fruit flies. (livebusiness.news)
  • We found that one-quarter of these unknown genes were lethal-when knocked out, they caused the flies to die, and yet nobody had ever known anything about them," says Freeman. (livebusiness.news)
  • That so many fundamental genes are not understood was eye-opening," Freeman says. (livebusiness.news)
  • PAX6 provides instructions for making proteins that drive tissue development in the fruit fly eye by turning on 'eye' genes and turning off 'non-eye' genes. (medlineplus.gov)
  • Learning about these phenotypes served as an intro to genetics, genes and proteins," Johnson said. (wesleyan.edu)
  • In order to understand which genes are best able to resist the effects of Aβ1-42 and tau, we utilized an AD fruit fly model. (uw.edu)
  • Did you know that blue eyes are the result of defective genes for pigment? (visionlearning.com)
  • Gene expression is the chemical pathway from genes to the gene products, such as proteins, that organisms can use. (visionlearning.com)
  • Only an individual with two genes for a defective enzyme will actually show the recessive trait, such as an inherited disease or condition, blue eyes, or a recessive peapod shape. (visionlearning.com)
  • At the MDC, he investigates how the nervous system in fruit flies develops and how the corresponding genes are regulated. (mdc-berlin.de)
  • The large majority of the early embryologists thought that the genes played only a minor role in development, for example by determining eye color, and that development is rather controlled by tissue interactions. (balzan.org)
  • all start with same types of cells, stem cells, containing same amount of genes, genes regulated by other factors and proteins within genome. (oneclass.com)
  • Look at flies and mice to drive development in humans: pathways and genetic mechanisms conserved, what occurs in flies, occur in humans, genomes sequenced so can find genes with mutant phenotypes. (oneclass.com)
  • The campers also learned about mutating DNA and how a gene is the code for making proteins. (wesleyan.edu)
  • Additionally, the genetic toolkit for positioning eyes is shared by all animals: The PAX6 gene controls where eyes develop in animals ranging from octopuses to mice and fruit flies. (wikipedia.org)
  • A splicing mutation in the Sik3 protein kinase gene causes a profound decrease in total wake time, owing to an increase in inherent sleep need. (nature.com)
  • Her later research with fruit flies showed that this gene plays a key role in how their eyes and optic nerves develop. (medlineplus.gov)
  • Subsequent Ca++ influx activates eye protein kinase C (ePKC), and calmodulin, which in turn modulate the activity of other visual proteins. (tdl.org)
  • Enables cyclin-dependent protein serine/threonine kinase regulator activity. (nih.gov)
  • Neuronal loss of the serine-threonine protein kinase Tao , a regulator of the Hippo signaling pathway, results in supernumerary boutons, each of which contain a normal number of active zones. (sdbonline.org)
  • Dillman is focused specifically on the proteins that nematode spit releases into hosts during an infection. (news-medical.net)
  • However, there are hundreds of proteins released in nematode venom during an infection, and only about 10 have been characterized and understood. (news-medical.net)
  • Laboratories studying nematode venom proteins often begin by observing the effects in mice and rats. (news-medical.net)
  • Genetic mutations that affect PAX6 can lead to significant issues such as cataracts and aniridia (a condition that affects the iris of the eye). (medlineplus.gov)
  • Dr. Kumar discovered that PAX6 proteins work together with another type of protein (called an epigenetic enzyme) to control how DNA is used in cells. (medlineplus.gov)
  • Biologist D.E. Nilsson has independently theorized about four general stages in the evolution of a vertebrate eye from a patch of photoreceptors. (wikipedia.org)
  • Higher-level similarities - such as the use of the protein crystallin in the independently derived cephalopod and vertebrate lenses - reflect the co-option of a more fundamental protein to a new function within the eye. (wikipedia.org)
  • Additionally, GOF of SATB1 (vertebrate ortholog of dve) in the eye also resulted in Wg upregulation and eye suppression. (udayton.edu)
  • Notch is a large receptor protein with segments inside the cell and in the membrane at the surface of the cell. (sciencedaily.com)
  • Like Notch, APP is a large protein that spans the cellular membrane. (sciencedaily.com)
  • CAH1 is cytoplasmic whereas CAH2 is a membrane-attached protein. (unifi.it)
  • show that a membrane protein protects cells in the eye and elsewhere in the body by quashing ROS production. (silverchair.com)
  • Because their eyes have similar structures to ours, geckos (like this Antilles gecko) are useful models for studying vision in humans. (medlineplus.gov)
  • As humans age, the crystallin protein in the lens breaks down to form peptide," said Premceski, a sophomore biomedical sciences major and member of the OU Honors College. (rochestermedia.com)
  • But baby birds in the nest need protein to grow, just as humans do. (awaytogarden.com)
  • Food - at certain times of the year they feed on insects , including caterpillars / pest flies , as colonies grow, they are attracted to foods consumed by humans. (astroextermination.ca)
  • Its DNA codes for sequence of 238 amino acids that forms a protein called Green Fluorescent Protein (GFP). (asu.edu)
  • The genetic code is not a way for cells to translate genetic information in DNA directly into chains of amino acids to make proteins. (visionlearning.com)
  • That work has demonstrated that presenilin mutations lead to the disproportionate formation from APP of a 42-amino-acid amyloid protein variant abundant in Alzheimer's disease plaques. (sciencedaily.com)
  • mutations: no functional copies of aniridia eyes embryos have no eye formation, lethality in utero. (oneclass.com)
  • The neuronal network responsible for paradoxical sleep and its dysfunctions causing narcolepsy and rapid eye movement (REM) behavior disorder. (nature.com)
  • Another captivating feature includes their large lidless eyes, which allow them excellent night vision promoting their nocturnal behavior. (reptileninja.com)
  • In addition, we investigate whether the inaD215 phenotype is due to displacement of ePKC from microdomains of calcium initiated by TRP channels, by calcium imaging of photoreceptors expressing visual proteins tagged with CaMgaroo, a Ca++-sensitive derivative of yellow fluorescent protein. (tdl.org)
  • Aβ1-42 and tau proteins lead to degradation in the eyes causing fusions and irregular shaping of ommatidia. (uw.edu)
  • One of the critical factors for the control of the protein levels during the cell cycle is the Anaphase Promoting Complex/Cyclosome (APC/C). This complex recognises proteins with specific signatures (or degrons) and targets them for degradation via the protein destruction machinery called the proteasome. (europa.eu)
  • In fruit fly photoreceptors InaD, a scaffolding protein containing 5 PDZ domains, organizes proteins involved in the visual signaling pathway into complexes within a microvillar stack of membranes known as the rhabdomere. (tdl.org)
  • We found that when the function of the APC/C is compromised, the cells that normally become photoreceptors fail to acquire their fate and unspecialised masses of cells are formed in the middle of the adult fly eyes. (europa.eu)
  • However, recent advances in the field allowed discovering that mitophagy seems to be only slightly affected in PINK1 KO mice and flies, putting into question the physiological relevance of this pathway in vivo in the whole organism. (bvsalud.org)
  • To study how the mutation works, Thompson, whose doctorate is in biological chemistry and genetics, has developed models of the disease in fruit flies and mice. (aaas.org)
  • We determine dopamine synthesis levels in retina samples (collected from mice) by using a research method called Western Blot, which allows us to quantify a target protein, tyrosine hydroxylase, that represents dopamine synthesis levels," said Sammane, who credits her mentors, Dr. Dao-Qi Zhang and Sheng-Nan Qiao, for guiding her though the experience. (rochestermedia.com)
  • To characterize the function of dve (member of DV patterning pathway) during development, we looked for its interacting partners and found that it interacts antagonistically with Hippo signaling to regulate optimum levels of expression of their common downstream target, Wg, to specify eye versus head fate, during growth and patterning in developing eye. (udayton.edu)
  • We modulated Hippo pathway in FUS-WT or mutant-FUS background and found that downregulation of Hippo pathway, exhibited significant rescue in the eye, but the exact mechanism of action was still unclear. (udayton.edu)
  • Several anterograde and retrograde signaling pathways, including the canonical Bone Morphogenic Protein (BMP) pathway , regulate synaptic development in vertebrates and invertebrates. (sdbonline.org)
  • Premceski, mentored by Drs. Frank Giblin and Vidhi Mishra, worked on a project examining the interaction between alpha crystallin protein and an alpha crystallin peptide using fluorescence polarization. (rochestermedia.com)
  • I will measure how different genotypes shape the effect of brain-specific Aβ and tau on lifespan and protein aggregation, and will use Genome Wide Association Studies to identify single nucleotide polymorphisms associated with variation in expression of Aβ and tau. (uw.edu)
  • Researchers have reported previously that Crb blocks Rac1, a protein that teams up with the enzyme NADPH oxidase to generate the ROS superoxide. (silverchair.com)
  • The quick developmental progression as well as the excellent genetic and biochemical accessibility of the fruit fly embryo are some of the reasons why Robert considers these insects to be an ideal model organism for his research. (mdc-berlin.de)
  • Some flesh fly larvae are internal parasites of other insects such as Orthoptera , and some, in particular the Miltogramminae , are kleptoparasites of solitary Hymenoptera . (wikipedia.org)
  • Poison frogs living in human care aren't poisonous, thanks to a "detox" diet of mild insects, like crickets and fruit flies. (si.edu)
  • Tiny zebrafish can also regrow parts of the eye, including neurons in the eye's retina (the light-sensitive tissue at the back of the eyeball). (medlineplus.gov)
  • In neurons, the abnormal production of the protein causes just about everything to go wrong, Thompson said. (aaas.org)
  • NGF does not work on all neurons, but since the discovery of NGF, a number of other related neurotrophin proteins, including a protein called brain-derived growth factor (BDNF) and two closely related proteins, neurotrophin 3 and neurotrophin 4/5, have been identified. (melkerscatering.se)
  • These proteins differ in terms of the types of neurons they act upon and the effects they exert. (melkerscatering.se)
  • In 1935, George Beadle and Boris Ephrussi developed a technique to transplant optic discs between fruit fly larvae. (asu.edu)
  • Flesh fly maggots occasionally eat other larvae, although this is usually because the other larvae are smaller and get in the way. (wikipedia.org)
  • Flesh flies and their larvae are also known to eat decaying vegetable matter and excrement , and they may be found around compost piles and pit latrines . (wikipedia.org)
  • Flesh flies can carry leprosy bacilli and can transmit intestinal pseudomyiasis to people who eat their larvae. (wikipedia.org)
  • Our preliminary results show significant variation in neuronal eye cell degeneration among DGRP lines, implying that neurodegeneration would also differ between DGRP lines if Aβ and tau were expressed in the nervous system. (uw.edu)
  • They differ from most flies in that they are ovoviviparous , opportunistically depositing hatched or hatching maggots instead of eggs on carrion , dung, decaying material, or open wounds of mammals, hence their common name. (wikipedia.org)
  • Methods to detect tau expression include light and scanning electron microscopy in the fly eye, confocal microscopy of primary neuronal cultures, and preparation of tissue homogenates for separation by sodium dodecyl sulfate polyacrylamide gel electrophoresis with analysis by Western blotting. (cmich.edu)
  • At several steps in its original production and in its signaling activity, the Notch protein is cut by other molecules in a process as yet little understood. (sciencedaily.com)
  • Rather, RNA molecules must be made as intermediaries along the way from DNA to the polypeptides that fold into proteins. (visionlearning.com)
  • protein-based molecules produced by living cells that bring about or speed up specific biochemical reactions in the organism, such as digestion. (visionlearning.com)
  • To determine whether Crb provides protection by curtailing ROS, the researchers gauged levels of these damaging molecules in fruit fly epithelial cells. (silverchair.com)
  • The girls also viewed a variety of mutant adult fly eyes with dissecting microscopes and, to build their skills in observation, built 3D models of these with modeling clay. (wesleyan.edu)
  • Researchers at the University of Pennsylvania Medical Center and other institutions have uncovered a biochemical connection between presenilin, a molecule involved in the development of Alzheimer's disease, and another protein that controls crucial aspects of developmental biology. (sciencedaily.com)
  • Small animals teach researchers big lessons about how vision works, how it can go wrong (and why), and new ways to treat eye diseases. (medlineplus.gov)
  • NIH-supported researchers continue to study fruit fly development, asking questions like, "What makes an eye an eye? (medlineplus.gov)
  • The findings from this experiment will help researchers understand the potential effect of this mutation in the human eye, he explained. (rochestermedia.com)
  • Nilsson and S. Pelger estimated in a classic paper that only a few hundred thousand generations are needed to evolve a complex eye in vertebrates. (wikipedia.org)
  • It's easy and inexpensive to work with flies, and there is much less red tape associated with them compared to vertebrates,' Dillman said. (news-medical.net)
  • Current research is investigating the genetic mechanisms underlying eye development and evolution. (wikipedia.org)
  • All eyed animals share much of the genetic machinery for eye development. (wikipedia.org)
  • they must originally have served a different purpose, before they were co-opted for eye development. (wikipedia.org)
  • Notch, first discovered in fruit flies just before World War I, is involved in critical intercellular signaling in a wide array of development processes, many to do with the patterning of tissues. (sciencedaily.com)
  • DV patterning marks first lineage restriction event during eye development, any deviation during this event during development results in defective organ formation. (udayton.edu)
  • Beadle and Ephrussi used their technique to study the development of the eye and eye pigment. (asu.edu)
  • Many of the molecular processes we investigate are evolutionarily conserved from fly to man, which allows us to draw direct, testable inferences not only about nervous system development specifically, but also about tissue development in general" the scientist explains. (mdc-berlin.de)
  • CAH2 in the eye of D. melanogaster may provide a new animal model for CA-related eye diseases. (unifi.it)
  • For the past three months, a select group of six undergraduate students has worked with faculty in Oakland University's Eye Research Institute (ERI) on projects investigating causes and potential cures for eye diseases such as glaucoma, cataracts and retinopathy. (rochestermedia.com)
  • The molecular and cellular mechanisms that determine the amount of rapid eye movement sleep (REMS) and non-REMS (NREMS) remain unknown. (nature.com)
  • We have expressed and purified D. melanogaster CAH1 and CAH2 as proteins of molecular weights 30kDa and 28kDa. (unifi.it)
  • Therefore, using the fruit fly allows us to faster and more easily obtain results that are likely to be applicable to mammals. (europa.eu)
  • Mammals are warm blooded animals that generate their own heat and generally have hair or fur covering all their bodies but their eyes. (factsanddetails.com)
  • Another 25 percent of them caused changes in the flies-phenotypes-that we could detect in many ways. (livebusiness.news)
  • Amongst other factors, one group of proteins called transcription factors (TFs) is crucial for regulating whether a cell will develop into, for example, a liver or a nerve cell. (mdc-berlin.de)
  • A new study reports on the crucial role the protein GRK2 plays in regulating the body's internal clock. (neurosciencenews.com)
  • As soon as transcription starts in the fruit fly embryo, the process of cellular specification commences and within only a few hours a pool of pluripotent cells develops into differentiated components of the nervous system. (mdc-berlin.de)
  • The epithelium has visibly broken down in a fly embryo lacking Crb (right) compared to a control embryo (left). (silverchair.com)
  • Previous studies indicate that the extent to which an individual is affected by the interaction of these proteins and the severity of AD is largely influenced by genetic variation. (uw.edu)
  • This suggests that the ancestor of eyed animals had some form of light-sensitive machinery - even if it was not a dedicated optical organ. (wikipedia.org)
  • The eye's retina is made up of photoreceptor (light-sensitive) cells and nerve cells in the optic nerve (which connects the eye to the brain). (medlineplus.gov)
  • Peripherin is a photoreceptor protein in the retina, which affects the regeneration of photoreceptor disks necessary for normal vision. (rochestermedia.com)
  • Many scientists have found the evolution of the eye attractive to study because the eye distinctively exemplifies an analogous organ found in many animal forms. (wikipedia.org)
  • The scientists think that presenilin is involved in the processing of two proteins called Notch and amyloid precursor protein (APP). (sciencedaily.com)
  • Scientists can create fruit flies that live a 250% longer life span. (selfgrowth.com)
  • This team found large quantities of ROS in eyes from flies that lacked Crb only in their eye cells. (silverchair.com)
  • There are currently two different models for scaffolding proteins: the "beads on a string" or "tethering" model where the order of the binding domains and their respective binding partners is unimportant, and the "specific quaternary structure" model where the specific stereochemical orientation of the domains is vital for proper signaling. (tdl.org)
  • The eye is really a fantastic model, too, because it's easily manipulated. (medlineplus.gov)
  • Discover more about the newt eye lens as a research model in this video . (medlineplus.gov)
  • After a short presentation on how a variety of biological objects appear when viewed with high magnification, the girls viewed and captured images of the fly pupal eye with a fluorescent microscope. (wesleyan.edu)
  • There are, six leg discs, two wing discs and two eye-antennal discs etc., which during metamorphosis, at the pupal stage, give rise to the legs, wings, eyes and antennae of the fly. (balzan.org)
  • A seroepidemiologic study in Malaysia implicated 4 fruit bat species, Pteropus hypomelanus , P. vampyrus , Cynopterus brachyotis , Eonycteris spelaea, and an insectivorous bat, Scotophilus kuhlii (2). (cdc.gov)
  • These proteins are chemically modified by polycomb enzymes and act as an additional reading block that is used sparingly by the cell. (mpg.de)
  • The girls also learned about the life-cycle of the fruit fly and set up an experiment to test the effects of feeding flies a high-sugar diet (this negatively affects the fly life-cycle, and is akin to inducing Type II Diabetes). (wesleyan.edu)
  • They can survive the winter eating silvery juniper berries (actually cones) that contain a high level of lipids, carbohydrates, and some protein. (jhwildlife.org)
  • To elucidate the mechanism of action, we modulated JNK signaling in FUS or mutant-FUS background and found that downregulation of JNK signaling also rescued FUS mediated neurodegeneration in eye. (udayton.edu)
  • He uses fruit fly models to study how a cell becomes one kind of tissue (like an eye) and not another (like a wing or an antenna). (medlineplus.gov)
  • He and his team found a way to study this process by turning off or "knocking out" both proteins at the same time. (medlineplus.gov)
  • A new study offers evidence between rapid eye movement during sleep, accelerated brain activity and dream images. (neurosciencenews.com)
  • A new study reports a lack of sleep can reduce aggression and affect reproductive fitness in fruit flies. (neurosciencenews.com)
  • Organization of proteins into macromolecular complexes is one way cells maximize the speed, specificity, and efficiency of signal transduction. (tdl.org)
  • When the lens is removed from a newt's eye, the immune system clears out any damaged cells and debris. (medlineplus.gov)
  • And with OCT, Dr. Del Rio-Tsonis can see how cells and tissues rearrange themselves to rebuild a critical part of the eye. (medlineplus.gov)
  • AAAS Fellow Leslie Thompson is using skin cells to create brain cells that have the abnormal protein that causes Huntington's Disease, and she is testing treatments with those cells. (aaas.org)
  • In recent years, Thompson's lab has been the first to discover how toxic proteins build up in diseased brain cells. (aaas.org)
  • In other research at the university's Sue & Bill Gross Stem Cell Research Center, she has been the first to use skin cells to create brain cells that have the abnormal protein that causes the disease, and she is testing treatments with those cells. (aaas.org)
  • Changes in the production of a protein called huntingtin alter the function of the cells. (aaas.org)
  • Although hummingbirds' eyes have a heightened sensitivity to colors in the red to yellow range, given the choice, they'll ignore color and head for the most nectar-rich flowers, like this . (awaytogarden.com)
  • Though this light is apparently too weak to be detected by the human eye, still, you have to wonder … could a few hypersensitive individuals really be aura-seers? (quiet-corner.com)
  • Though we're working with flies, this work has real potential to impact human health. (news-medical.net)
  • Eyes vary in their visual acuity, the range of wavelengths they can detect, their sensitivity in no light, their ability to detect motion or to resolve objects, and whether they can discriminate colours. (wikipedia.org)
  • The first fossils of eyes found to date are from the Ediacaran period (about 555 million years ago). (wikipedia.org)
  • We found that eye enlargement phenotype resulting from GOF of hpo in dve domain, is not due to hpo mediated cell death, but by regulating retinal differentiation. (udayton.edu)
  • We found significant genetic variation in ommatidial circularity and area, two measures of eye quality. (uw.edu)
  • Eyes and other sensory organs probably evolved before the brain: There is no need for an information-processing organ (brain) before there is information to process. (wikipedia.org)
  • Based on current progress, this new project will continue exploring variation in DGRP lines, but this time we will express them in the fly brain. (uw.edu)
  • These fruit flies have been the subject of research for more than a century because they are easy and inexpensive to breed, have a short life cycle, produce lots of young, and can be genetically modified in numerous ways. (livebusiness.news)
  • Watch this video to learn more about fruit flies as animal models in vision research. (medlineplus.gov)
  • The students - Maya Sammane, Adam Seidel, Maria Donovan, Anthony Premceski, Reham Karana and Regan Miller - took part in OU's Summer Undergraduate Program in Eye Research (SUPER), helping carry out experiments that could lead to breakthroughs in treatments for vision loss. (rochestermedia.com)
  • I came into the Eye Research Institute with little knowledge about research and came out knowing that I will be involved in research throughout my lifetime, as a doctor. (rochestermedia.com)