• However, antibody responses also appear essential for resistance against certain viruses such as enterovirus ( 9 ) and rabies virus ( 10 ), and there are numerous examples of antibodies curing or preventing viral infections ( 11 - 17 ). (pnas.org)
  • Cell numbers, distribution, shape, and regional variation throughout the murine hippocampal formation from the adult brain Allen Reference Atlas. (bioportfolio.com)
  • The results indicate that resolution of retroviral infections may require more complex immunological responses than have been found for most other viruses. (pnas.org)
  • Expression of mouse mammary tumor virus superantigen mRNA in the thymus correlates with kinetics of self-reactive T-cell loss. (springer.com)
  • Identifying substrates that interact with SH2 domains and probing the way these interactions contribute to transformation provide one approach to understanding how SH2-mediated signaling specificity contributes to host-virus interaction. (asm.org)
  • To test such an approach, we used plasma from a patient (CLL831) with concomitant B-cell chronic lymphocytic leukemia (CLL) and polycythemia vera (PV), who donated blood made available from periodic phlebotomy for PV. (springer.com)
  • Therefore, the motor neurons which degenerate in these diseases do not appear to be infected by the virus and are most likely affected indirectly ( 43 , 49 , 50 , 52 , 55 ). (asm.org)
  • More than a dozen MAbs are now licensed for clinical use for diverse indications, such as prophylaxis of respiratory syncytial virus disease in neonates, treatment of Crohn's disease, prevention of coronary artery closure after angioplasty, and therapy of refractory rheumatoid arthritis ( 65 ). (asm.org)
  • Most likely this resolution depends on the specific virus and host involved, and often more than one aspect of the immune response is important, if not essential. (pnas.org)
  • The classical functions of specific Abs include direct Ab activities, such as toxin and virus neutralization, and indirect activities that require other immune system components, such as opsonization and complement activation. (asm.org)