• They may also undergo a conformational change to participate in the formation of transient multi-protein complexes with other enzymes in the various pathways diverging from the general phenylpropanoid biosynthetic pathway. (wikipedia.org)
  • However, many enzymes can bind to different combinations of proteins to form groups (or 'complexes') with a variety of three-dimensional shapes, so there may be a variety of enzyme complexes in the solution. (elifesciences.org)
  • The center of telomerase has a protein called TERT that forms complexes with other proteins. (elifesciences.org)
  • The experiments show that these complexes can contain either one or two TERT proteins. (elifesciences.org)
  • Further experiments used a mutant form of the TERT protein that cannot interact with other TERT molecules and found that complexes that contain this mutant protein still have normal enzyme activity. (elifesciences.org)
  • Studies have shown that these enzymes interact via protein-protein interactions. (wikipedia.org)
  • Through FLIM FRET, it was shown that CHS interacts with chalcone isomerase (CHI), a consecutive step enzyme, as well as other non-consecutive step enzymes flavanone 3-hydroxylase (F3H), dihydroflavonol 4-reductase (DFR), and flavonol synthase I. Naringenin-chalcone synthase uses malonyl-CoA and 4-coumaroyl-CoA to produce CoA, naringenin chalcone, and CO2. (wikipedia.org)
  • Some enzymes are made of just one component protein that works on its own, but others are made of multiple proteins that are all required for the enzyme to work properly. (elifesciences.org)
  • Therefore, a future challenge will be to refine the method to allow experiments to use much less protein, which would more closely reflect how telomerase is produced in cells. (elifesciences.org)
  • Studies have shown that these enzymes interact via protein-protein interactions. (wikipedia.org)