• Several studies suggest that the cardiovascular disease (CVD) mortality rates of persons with type 2 diabetes are about two to four times higher than those of the general population. (intechopen.com)
  • Conclusions Our findings suggest BA measures may be complementary in predicting risk for mortality and age-related disease. (deepdyve.com)
  • Several of the measures have been related to risk for mortality (4,6,7) and physical and cognitive decline (5-7). (deepdyve.com)
  • DNA methylation age predicts mortality independent of chronologic age and other risk factors (11,12) and is associated with some age-related conditions such as brain aging (13), but not with coronary heart disease (14). (deepdyve.com)
  • We hypothesized that different types of BA measures (clinical, inflammatory, and genomic) make unique contributions to age-related disease risk and all-cause mortality. (deepdyve.com)
  • Thus, International Civil Aviation Organization (ICAO) recommends to country members to use routinely homogeneous cardiovascular likelihood management recommendations and ASCVD likelihood estimate scores in aeromedical risk assessment to help alleviating morbidity and mortality in aeronautical setting (area). (scirp.org)
  • Main outcome measure Conclusion Cite this as: BMJ 2019;366:l4414 Incident dementia, identified through linkage to Adherence to the Life Simple 7 ideal cardiovascular http://dx.doi.org/10.1136/bmj.l4414 hospital, mental health services, and mortality health recommendations in midlife was associated Accepted: 12 June 2019 registers until 2017. (readkong.com)
  • The authors add it can take decades to progress to a clinically detectable degree, and thus further follow-up of our cohort is necessary to determine whether a substantial absolute increase in morbidity and mortality from therapy-related cardiovascular disease will emerge. (natap.org)
  • 1 While antiretroviral therapy (ART) has reduced morbidity and mortality in people living with HIV (PLHIV), 2 complications associated with ageing such as cardiovascular disease (CVD), cancer, osteoporosis, and other end-organ diseases are increasing. (sajhivmed.org.za)
  • Cardiorespiratory fitness, body composition, and all-cause and cardiovascular disease mortality in men. (jamanetwork.com)
  • Cardiorespiratory fitness as a quantitative predictor of all-cause mortality and cardiovascular events in healthy men and women: a meta-analysis. (jamanetwork.com)
  • Influences of cardiorespiratory fitness and other precursors on cardiovascular disease and all-cause mortality in men and women. (jamanetwork.com)
  • Cardiorespiratory fitness and classification of risk of cardiovascular disease mortality. (jamanetwork.com)
  • To assess the association between coffee consumption and mortality from cardiovascular disease (CVD), cancer, and all causes during 18 years of follow-up in men and 24 years of follow-up in women. (acpjournals.org)
  • Sex-specific Cox proportional hazard models were used to investigate the association between coffee consumption and incidence of all-cause and disease-specific mortality in a prospective cohort study. (acpjournals.org)
  • This inverse association was mainly due to a moderately reduced risk for CVD mortality and was independent of caffeine intake. (acpjournals.org)
  • Decaffeinated coffee consumption was associated with a small reduction in all-cause and CVD mortality. (acpjournals.org)
  • The current study aimed to identify the best heart rate corrected QT interval for a non-hospitalized Iranian population based on cardiovascular mortality. (biomedcentral.com)
  • Practically, it is suggested that physicians use QTcB for a better evaluation of cardiac mortality risk. (biomedcentral.com)
  • 1 The mortality and morbidity of AF is well established, with a higher risk of stroke and heart failure in older patients with comorbidities. (aerjournal.com)
  • The vast majority of well-done prospective studies indicate that, in comparison with non-drinkers, moderate, non-binge-drinking older adults have a lower risk of cardiovascular disease and total mortality. (alcoholresearchforum.org)
  • From 1980 to 2017, the global trend for CVD mortality showed an increase by about 21% [ 2 ]. (biomedcentral.com)
  • OBJECTIVES: Proper risk assessment is important for the primary prevention of atherosclerotic cardiovascular disease (ASCVD). (bvsalud.org)
  • Background: Flight and cabin crew are known to be at increased risk for atherosclerotic cardiovascular disease (ASCVD). (scirp.org)
  • Cardiovascular disease risk was estimated by Framingham Cardiovascular and Heart Disease (FHS-CVD, FHS-CHD), Atherosclerotic Cardiovascular Disease (ASCVD) and D:A:D 2010 and 2016 risk prediction models for HIV-infected participants of the Ndlovu Cohort Study, Limpopo, rural South Africa. (sajhivmed.org.za)
  • ASCVD indicates atherosclerotic cardiovascular disease. (jamanetwork.com)
  • 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. (jamanetwork.com)
  • For decades, the non-steroidal anti-inflammatory drug (NSAID) acetylsalicylic acid (ASA) has been widely used at a low dose of 100 to 300 mg per day for secondary prevention of atherosclerotic cardiovascular disease (ASCVD) [ 1 ]. (biomedcentral.com)
  • Actually in the 5th Korean National Health and Nutrition Examination Survey, individuals with sarcopenic obesity defined by low muscle mass and high BMI had significantly high 10-year CVD risk determined using the Framingham risk model, whereas sarcopenic non-obese and non-sarcopenic obese individuals were not associated with an increased 10-year CVD risk [ 15 ]. (biomedcentral.com)
  • This study sought to develop a 10-year risk prediction model for incident ASCVD. (bvsalud.org)
  • ASCVD was defined as a composite of cardiovascular death, myocardial infarction, and stroke. (bvsalud.org)
  • The predictors of ASCVD included in the model were age, smoking status, diabetes, systolic blood pressure, lipid profiles, urine protein, and lipid-lowering and blood pressure-lowering treatment. (bvsalud.org)
  • Compared with our model, both FRS and PCE showed worse calibration, overestimating ASCVD risk in the Korean population. (bvsalud.org)
  • CONCLUSIONS: Through a nationwide cohort, we developed a model for 10-year ASCVD risk prediction in a contemporary Korean population. (bvsalud.org)
  • However, ASCVD risks have not yet been compared in flight and cabin crew in low resource settings like sub-Saharan Africa. (scirp.org)
  • Objectives: To assess absolute ASCVD risk estimate and its clinical correlates among flight and cabin crew. (scirp.org)
  • Methods: From June 1st 2015 to December 30th 2015, 379 consecutive aviation navigants (Flight crew: 62.5%, pilots: 46.2%, women: 29.6%, Caucasians 23.2%) were enrolled in a cross-sectional survey of ASCVD risk estimate using the Framingham tools. (scirp.org)
  • We modeled the risk of moderate and high ASCVD estimate in a stepwise logistic regression. (scirp.org)
  • Results: Low, moderate and high ASCVD risk estimates were observed respectively in 248 (65.4%), 64 (16.9%), and 67 (17.7%) navigants. (scirp.org)
  • Conclusion: In the present case series, moderate and high ASCVD risk estimates were present in 3 out of 10 navigants and racial, traditional risk factors and flight crew status were the main correlates of these ASCVD risk estimates. (scirp.org)
  • Due to less physical activity associated with their professional life, the aircrew could be considered as a group at high ASCVD risk. (scirp.org)
  • High 10-year CVD risk was predicted for 2.9%, 0.5%, 0.7%, 3.1% and 6.6% of the study participants by FHS-CVD, FHS-CHD, ASCVD, and D:A:D 2010 and 2016. (sajhivmed.org.za)
  • Kappa statistics ranged from 0.34 for ASCVD to 0.60 for FHS-CVD as compared to the D:A:D 2010 risk prediction model. (sajhivmed.org.za)
  • Among women aged 40 to 79, ASCVD absolute risk was 6.0% for What is already known on this topic? (cdc.gov)
  • Among men aged 40 to 79, however, this association has not been characterized using contemporary the corresponding absolute ASCVD risks were 9.9%, 11.1%, and US primary prevention assessment standards for depression and CVD. (cdc.gov)
  • ASCVD risk and substantially elevated lifetime CVD risk among younger people ineligible for ASCVD risk assessment. (cdc.gov)
  • 1), is a leading cause of disability (2), and in 2018 was noted in pression with 1) 10-year atherosclerotic CVD (ASCVD) risk for more than 10 million office visits in the US (3). (cdc.gov)
  • Cardiovascular disease (CVD), largely driven by the combined effect of several modifiable risk factors such as smoking and obesity, is the leading contributor accounting for one-fifth of the health gap ( 1 ). (frontiersin.org)
  • BACKGROUND: Sensitive general cardiometabolic risk assessment tools of modifiable risk factors would be helpful and practical in a range of primary prevention interventions or for preventive health maintenance. (cdc.gov)
  • PURPOSE: To develop and validate a cumulative general cardiometabolic risk score that focuses on non-self-reported modifiable risk factors such as glycosylated hemoglobin (HbA1c) and BMI so as to be sensitive to small changes across a span of major modifiable risk factors, which may not individually cross clinical cut-off points for risk categories. (cdc.gov)
  • Gender-specific Cox proportional hazards models were considered to evaluate the effects of non-self-reported modifiable risk factors (blood pressure, total cholesterol, high-density lipoprotein cholesterol, smoking, BMI, and HbA1c) on general CVD risk. (cdc.gov)
  • CONCLUSIONS: This study presents a risk factor algorithm that provides a convenient and informative way to quantify cardiometabolic risk on the basis of modifiable risk factors that can motivate an individual's commitment to prevention and intervention. (cdc.gov)
  • Standardization of the CRP assay is required before this test may be clinically useful, and whether CRP is a truly modifiable risk factor remains unclear. (medscape.com)
  • According to the Korean Heart Study that evaluated data from 1997 to 2011, the attributable risk of dyslipidemia for CVD was 8.7% in men and 4.1% in women among modifiable risk factors [ 8 ]. (biomedcentral.com)
  • It is therefore considered necessary to develop specific tools to evaluate and reduce CVD risk in this population. (intechopen.com)
  • While the 2015-2020 Dietary Guidelines for Americans advise substituting both monounsaturated and polyunsaturated fatty acids for SFA, evidence supports other nutrient substitutions that will also reduce CVD risk. (preprints.org)
  • Replacing SFA with protein, especially plant protein may also reduce CVD risk. (preprints.org)
  • While dairy fat (milk, cheese) is associated with a slightly lower CVD risk compared to meat, dairy fat results in a significantly greater CVD risk relative to unsaturated fatty acids. (preprints.org)
  • Our study shows greater CVD risk for both clinical and subclinical depres- depression, 53.2% for mild depression, and 66.5% for major de- sion, including higher lifetime CVD risk among adults aged 20 to 39 years. (cdc.gov)
  • Iran is the second-largest country in the MENA with the increasing prevalence of obesity, T2DM, CKD, and hypertension leading to CVD. (biomedcentral.com)
  • Consistent with similar work (15), we hypothesized that mild and cing CVD risk are therefore paramount for public health, and the moderate depression are associated with higher 10-year and life- prevalence and comorbidity of these conditions underscore the im- time CVD risk relative to no depression. (cdc.gov)
  • Epidemiological studies have identified a vast array of risk factors that account for its high prevalence and the difficult implementation of primary prevention measures. (aerjournal.com)
  • Prevalence of prior CVD and predicted 10-year CVD risk for those free of CVD by SBP category in those not undergoing treatment and those undergoing treatment. (jamanetwork.com)
  • This study aimed to evaluate (1) evaluate whether a Web-based cardiovascular disease (CVD) risk communication tool (Heart Age tool) was reaching users at risk of developing CVD, (2) the impact of awareness of total cholesterol (TC), HDL-cholesterol (HDL-C), and systolic blood pressure (SBP) values on the risk estimates, and (3) the key predictors of awareness and reporting of physiological risk factors. (jmir.org)
  • Methods In Framingham Offspring participants at Exams 7 (1998-2001, mean age 62 ± 10) and 8 (2005-2008, mean age 67 ± 9), we used the Klemera-Doubal method to estimate clinical BA and inflammatory BA and computed the difference (∆age) between BA and CA. Clinical ∆age was computed at Exam 2 (1979-1983, mean age 45 ± 10). (deepdyve.com)
  • Methods Study Sample The Framingham Heart Study (FHS) is a community-based longitudinal cohort study initiated in 1948 to study determinants of cardiovascular disease (CVD) and its risk factors. (deepdyve.com)
  • METHODS: We prospectively followed 2,359 cardiovascular disease (CVD)-free subjects from the Framingham offspring cohort over a 14-year follow-up. (cdc.gov)
  • Comparing Explainable Machine Learning Approaches With Traditional Statistical Methods for Evaluating Stroke Risk Models: Retrospective Cohort Study. (cdc.gov)
  • Furthermore, the ability of these methods to track changes in CVD risk over time and in response to treatment remains unclear. (biomedcentral.com)
  • Methods Female patients with SLE of white British ancestry were recruited from clinics in the North-West of England and had a baseline clinical and CVD risk assessment including measurement of carotid intima-media thickness (CIMT) and plaque using B-mode Doppler ultrasound. (bmj.com)
  • Various machine-learning methods were adopted on the training set to achieve high-accuracy prediction models and the results were compared with traditional statistical methods and well-known risk scales. (jmir.org)
  • Comparison analysis showed that nonlinear models (K-nearest neighbor AUC 0.908, random forest AUC 0.938) outperform linear models (logistic regression AUC 0.865) on the same datasets, and machine-learning methods significantly surpassed traditional risk scales or fixed models (eg, Framingham cardiovascular disease risk models). (jmir.org)
  • mHealth apps have the prospect of participant convenience, collection of 'real-world' data, flexibility to pivot research agendas to focus on timely health issues (such as disparities in CVD and the long-term effects of COVID-19 pandemic), as well as the potential to be conducted in large and diverse populations. (jmir.org)
  • However, little is known regarding whether sarcopenic obesity determined using whole body DXA could predict incident cardiovascular disease (CVD). (biomedcentral.com)
  • Depression is also people aged 40 to 79 years and 2) high lifetime CVD risk preval- an established marker of incident cardiovascular disease (CVD) ence for people aged 20 to 39 years. (cdc.gov)
  • Design A state transition model was developed using the Scottish Heart Health Extended Cohort (SHHEC) linked to Scottish morbidity and death records. (bmj.com)
  • The development of the Chronic Care Model (CCM) for the care of patients with chronic diseases has focused on the integration of taking charge of the patient and his family within primary care. (intechopen.com)
  • Compared to the general population, individuals with depression have an increased risk for cardiovascular diseases. (frontiersin.org)
  • Projections assume that depression will be the leading cause of disability worldwide by 2030 ( 9 ), which might be partly due to the high comorbidity with cardiovascular diseases (CVDs) ( 10 , 11 ). (frontiersin.org)
  • The Global Burden of Disease Study 1 estimated that in 2010 cardiovascular disease (CVD), including rheumatic heart diseases, hypertensive diseases, ischaemic heart diseases, pulmonary heart disease, other forms of heart disease, cerebrovascular diseases (CBVDs), diseases of arteries and diseases of veins, was the cause of death in approximately 30% of all global deaths. (bmj.com)
  • Web-based health applications, such as self-assessment tools, can aid in the early detection and prevention of diseases. (jmir.org)
  • Noncommunicable diseases, including cardiovascular, metabolic and respiratory diseases, among others, are the major medical challenge of the 21st century. (ersjournals.com)
  • Noncommunicable diseases include a number of highly prevalent diseases, such as cardiovascular diseases, chronic respiratory diseases, cancer, diabetes, neuropsychiatric disorders and arthritis [ 2 ]. (ersjournals.com)
  • Secondary outcomes were the proportion of clients with elevated risk that had follow-up actions recorded. (frontiersin.org)
  • Explainable Risk Prediction of Post-Stroke Adverse Mental Outcomes Using Machine Learning Techniques in a Population of 1780 Patients. (cdc.gov)
  • Cardiovascular disease (CVD) outcomes and associated risk factors in a medicare population without prior CVD history: an analysis using statistical and machine learning algorithms. (cdc.gov)
  • It revealed good discrimination between low- and high-risk populations for the combined outcomes. (biomedcentral.com)
  • A more comprehensive approach to CVD risk management taking into account disease factors such as severity and anticardiolipin antibody status may be necessary to improve CVD outcomes in this high-risk population. (bmj.com)
  • Furthermore, compared to non-users, users of low-dose ASA for 10 years or longer (who likely use it because they have CHD or a related diagnosis putting them at an increased risk for cardiovascular events) demonstrated a strong protective effect on all dementia outcomes, especially for VD (HR [95% CI]: 0.48 [0.42 to 0.56]) whereas no protective associations were observed with shorter low-dose ASA use. (biomedcentral.com)
  • Over a median follow-up period of 7.67 years, 1281 (5.01%) participants in UK Biobank developed CVD events. (biomedcentral.com)
  • Results Of 200 patients with a baseline scan, 124 (62%) patients had a second assessment at a median (IQR) of 5.8 (5.2-6.3) years follow-up. (bmj.com)
  • The two RCTs published so far excluded subjects with CVD, which are the main users of low-dose ASA in clinical routine, included rather old study populations (median ages of 65 and over 70 years) and had short median treatment durations of 4.4 and 4.7 years [ 7 ]. (biomedcentral.com)
  • Regarding long-term patterns of alcohol intake over "middle age" (the pattern between assessments at a median age of about 45 years to that at about 61 years), the authors used their repeated assessments of consumption to construct trajectories of intake. (alcoholresearchforum.org)
  • In 2009, the European League Against Rheumatism (EULAR) taskforce recommended screening, identification of CVD risk factors and CVD risk management largely based on expert opinion. (bmj.com)
  • It is not uncommon for asymptomatic individuals without identified cardiovascular risk factors to present with atherosclerosis-related adverse events. (bvsalud.org)
  • We aimed to evaluate the predictors of subclinical coronary atherosclerosis in individuals without traditional cardiovascular risk factors. (bvsalud.org)
  • We analyzed 2,061 individuals without identified cardiovascular risk factors who voluntarily underwent coronary computed tomography angiography as part of a general health examination. (bvsalud.org)
  • Therefore, we examined whether common physiological cardiovascular risk factors differ between patients with depression and healthy (non-depressed) controls, whether patients and controls differ in CRF, and whether higher CRF is associated with a lower cardiovascular risk in both patients and healthy controls. (frontiersin.org)
  • Additionally, we examined whether within the patient sample, cardiovascular risk factors differ between patients with mild, moderate and severe depression, and whether the relationship between symptom severity and cardiovascular risk is moderated by patients' CRF levels. (frontiersin.org)
  • In multivariable regression models, the factors significantly and directly associated with the omega-3 index were age, female sex, higher education, fish oil supplementation, dietary intake of EPA + DHA, aspirin use, lipid pharmacotherapy, and LDL-cholesterol. (nih.gov)
  • However, there are concerns as to whether such tools actually reach users with elevated disease risk (where prevention efforts are still viable), and whether inaccurate or missing information on risk factors may lead to incorrect evaluations. (jmir.org)
  • Heart Age users (N=2,744,091) were mostly in their 20s (22.76%) and 40s (23.99%), female (56.03%), had multiple (mean 2.9, SD 1.4) risk factors, and a Heart Age exceeding their chronological age (mean 4.00, SD 6.43 years). (jmir.org)
  • The Heart Age tool reached users with low-moderate CVD risk, but with multiple elevated CVD risk factors, and a heart age higher than their real age. (jmir.org)
  • Subgroups at risk of not knowing their risk factors are identifiable and should be specifically targeted in health awareness programs. (jmir.org)
  • Quantifying cardiometabolic risk using modifiable non-self-reported risk factors. (cdc.gov)
  • The implementation and success of such a strategy require the identification of groups at risk for CVD and associated risk factors. (scirp.org)
  • What is already known on this topic Introduction Pathophysiological hallmarks of dementia appear Dementia is a progressive multifactorial disease involving pathophysiological 15-20 years before clinical symptoms,1 highlighting changes over a long preclinical period the need for a long follow-up to identify risk factors The Life Simple 7 cardiovascular health score has been put forward as a potential and protective factors. (readkong.com)
  • Most CVDs can be prevented by addressing behavioral risk factors. (biomedcentral.com)
  • 1 2 Many questions remain unanswered, particularly relating to risk stratification and factors influencing the initiation and progression of atherosclerosis. (bmj.com)
  • While it is clear that traditional cardiovascular disease (CVD) risk factors play an important role, 3 several studies have demonstrated that disease-specific factors are also important and as a result, traditional risk prediction models perform poorly in SLE. (bmj.com)
  • Marginal effect analysis showed that both traditional and EHR factors exhibited highly nonlinear characteristics with respect to the risk scores. (jmir.org)
  • Other factors besides combination therapy appear to contribute to the risk and can be addressed: cholesterol, tryglicerides, exercise, diet, smoking. (natap.org)
  • This finding is plausible because combination antiretroviral therapy can cause adverse metabolic changes that are known risk factors for cardiovascular disease. (natap.org)
  • Other known risk factors for myocardial infarction probably contributed to the occurrence of these events. (natap.org)
  • [ 24 ] The calculator uses a combination of clinical and laboratory risk factors to estimate risk. (medscape.com)
  • For patients 20-79 years of age who do not have existing clinical atherosclerotic CVD, the guidelines recommend assessing clinical risk factors every 4-6 years. (medscape.com)
  • It was soon recognized that the latter might also be accompanied by certain risk factors, different food consumptions [ 2 , 3 ], and the opposite anatomical picture at autopsy [ 4 , 5 , 6 ], all elements pointing to potential etiological differences that should be the foundation of differentiating nomenclature and classification. (mdpi.com)
  • In the total sample, participants with good CRF had more favourable scores across nearly all risk markers than counterparts with poor CRF. (frontiersin.org)
  • RBC samples (n = 3196) drawn between 2005 and 2008 from participants in the Framingham Study [Examination 8 of the Offspring cohort plus Examination 3 of the Omni (minorities) cohort] were analyzed for fatty acid composition by gas chromatography. (nih.gov)
  • Higher cardiovascular 4 Inserm, U970, Integrative Participants health score was associated with a lower risk of Epidemiology of Cardiovascular 7899 participants with data on the cardiovascular dementia (hazard ratio 0.89 (0.85 to 0.95) per 1 point Disease, Paris Descartes University, Paris, France health score at age 50. (readkong.com)
  • A total of 25,563 participants from UK Biobank who were initially free of CVD were included in the current study. (biomedcentral.com)
  • Compared with participants in the highest tertile of RNFL thickness, the risk of incident CVD was significantly increased in participants in the lowest thickness tertile (HR = 1.18, 95% CI: 1.01-1.38, p = 0.036). (biomedcentral.com)
  • Compared with an Université de Paris, 75010 Paris, France cardiovascular health score at age 50 and incidence of incidence rate of dementia of 3.2 (95% confidence 2 Department of Epidemiology dementia. (readkong.com)
  • However, the association between retinal nerve fiber layer (RNFL) thickness and the incidence of CVD events remains inconclusive, and relevant longitudinal studies are lacking. (biomedcentral.com)
  • Cox regression models with inverse probability of treatment weighting to model the underlying cardiovascular risk were used to assess the associations of low-dose ASA use with all-cause dementia, AD, and VD incidence in community-dwelling older adults from the German ESTHER study ( N = 5258) and the UK Biobank ( N = 305,394). (biomedcentral.com)
  • During the event accrual period, the cumulative incidence rates of CVD between the two AIP trajectory groups were estimated using Kaplan-Meier analysis with the log-rank test. (biomedcentral.com)
  • The increasing AIP trajectory group had a significantly higher cumulative incidence rate of CVD than the decreasing AIP trajectory group. (biomedcentral.com)
  • This large international study in 20,000 individuals finds the annual rate for myocardial infarction was low 0.6% but that combination therapy increased the risk 26% per year. (natap.org)
  • In addition, the relative increase in the risk of myocardial infarction per year cannot be extrapolated beyond the duration of follow-up in the study…… …….the annual rate of myocardial infarction, even among those exposed to therapy for four to six years, was less than 0.6 percent, and only a portion of the apparent excess risk could be attributed to combination antiretroviral therapy. (natap.org)
  • Hence, the substantial benefits of combination antiretroviral therapy continue clearly to outweigh the increased risk of myocardial infarction associated with this therapy. (natap.org)
  • Conversely, significant contributions from diabetes, hypertension, and lipodystrophy were not identified…… we found no evidence to suggest that the duration of HIV-1 infection, the level of prior immunodeficiency, or the degree of HIV-1 RNA replication affected the association between exposure to therapy and the risk of myocardial infarction. (natap.org)
  • New guidelines on screening for cardiovascular risk, released in late 2013 by the American Heart Association/American College of Cardiology (AHA/ACC), recommend use of a revised calculator for estimating the 10-year risk of developing a first atherosclerotic CVD event, which is defined as nonfatal myocardial infarction, death from coronary heart disease, or stroke (fatal or nonfatal) in a person who was initially free from atherosclerotic CVD. (medscape.com)
  • Cardiorespiratory fitness and risk of prostate cancer: findings from the Aerobics Center Longitudinal Study. (jamanetwork.com)
  • Development and validation of a machine learning-based prognostic risk stratification model for acute ischemic stroke. (cdc.gov)
  • Cardiovascular disease/stroke risk stratification in deep learning framework: a review. (cdc.gov)
  • In contrast, the markers currently used for CVD risk stratification are non-specific (e.g., age and smoking), measures target/end organ damage (e.g., serum creatinine levels and albuminuria), or have low precision (e.g., blood pressure and LDL cholesterol levels). (biomedcentral.com)
  • Objectives We aimed to describe the rate and determinants of carotid plaque progression and the onset of clinical cardiovascular disease (CVD) in a UK SLE cohort. (bmj.com)
  • Clinical CVD events between visits were also noted. (bmj.com)
  • All aspects of a biological process from biochemical, genetic and cellular to clinical and environmental can be integrated using computational models to derive unique signatures from vast amounts of data. (europeanpharmaceuticalreview.com)
  • MAY 2022 sion and CVD are associated with premature death, and both are prognostic for incident CVD (5), we compared CVD risk for both principal contributors to the rise in disability-adjusted life years mild and major depression relative to people without depression. (cdc.gov)
  • Awareness of physiological risk factor values was higher among diabetics (OR 1.47, 95% CI 1.46-1.50 and OR 1.74, 95% CI 1.71-1.77), those with family history of CVD (OR 1.22, 95% CI 1.22-1.23 and OR 1.43, 95% CI 1.42-1.44), and increased with age (OR 1.05, 95% CI 1.05-1.05 and OR 1.07, 95% CI 1.07-1.07). (jmir.org)
  • Physical activity and the prevention of cardiovascular disease: from evolution to epidemiology. (jamanetwork.com)
  • Where risk has been identified, further improvement in follow-up management is required to prevent CVD onset and reduce future burden in Australia's Indigenous population. (frontiersin.org)
  • Development and validation of explainable machine-learning models for carotid atherosclerosis early screening. (cdc.gov)
  • Patients with depression and healthy controls differ in several cardiovascular risk markers, putting patients at increased risk for CVDs. (frontiersin.org)
  • Thus, identifying individuals at the highest risk of developing cardiovascular event at an early stage is pivotal for the tailoring of timely interventions to preventing CVD and its related complications. (biomedcentral.com)
  • Previous studies have reached conflicting conclusions on this issue, some supporting our findings and others not, but an Editorial by Peter Sklar & Henry Mazur says taken in aggregate, the weight of the evidence suggests that HIV-infected patients treated with combination antiretroviral regimens are at increased risk for the development of premature atherosclerotic complications. (natap.org)
  • Conclusions Our model can be used to estimate the impact of primary prevention interventions on life expectancy and can assess the impact of interventions on inequalities. (bmj.com)
  • The study aimed to assess cardiovascular risk classification of common cardiovascular disease (CVD) risk prediction models compared to the Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) 2010 and 2016 models in people living with HIV. (sajhivmed.org.za)
  • For patients with elevated 10-year risk, clinicians should communicate risk data and refer to the AHA/ACC guidelines on blood cholesterol and obesity. (medscape.com)
  • Sarcopenic obesity, defined as reduced skeletal muscle mass and power with increased adiposity, was reported to be associated with cardiovascular disease risks in previous cross-sectional studies. (biomedcentral.com)
  • The aim of this study was to investigate the impact of sarcopenic obesity on incident CVD in patients with type 2 diabetes. (biomedcentral.com)
  • The present data suggest that the whole body DXA is valuable in the diagnosis of sarcopenic obesity (high A/G ratio or android fat mass with low SMI) to determine the risk of CVD events in patients with type 2 diabetes. (biomedcentral.com)
  • Meanwhile, sarcopenic obesity classified with low SMI, and high %BF or BMI was not associated with incident CVD. (biomedcentral.com)
  • In addition to obesity, sarcopenia, defined as loss of skeletal muscle mass and strength with aging, has been reported to be associated with not only physical disability but also CVD. (biomedcentral.com)
  • Therefore, it is conceivable that individuals with sarcopenic obesity are at a high risk for incident CVD. (biomedcentral.com)
  • Kappa statistics were used to determine agreement between CVD risk prediction models. (sajhivmed.org.za)
  • With the exception of the D:A:D model, all other risk prediction models classified fewer people to be at high estimated CVD risk. (sajhivmed.org.za)
  • Retinal structural abnormalities have been found to serve as biomarkers for cardiovascular disease (CVD). (biomedcentral.com)
  • A study by Paynter et al found that models incorporating HbA 1c levels significantly improved prediction of CVD risk among patients with diabetes. (medscape.com)
  • This study utilizes data from a large-scale quality improvement program to examine variation in documented CVRA as a primary prevention strategy for individuals without prior CVD across four Australian jurisdictions. (frontiersin.org)
  • By contrast, coffee consumption was not statistically significantly associated with risk for cancer death after adjustment for potential confounders. (acpjournals.org)
  • Compared to the decreasing AIP trajectory group, the increasing AIP trajectory group had a higher risk of incident CVD (HR: 1.31, 95% CI: 1.02-1.69) after adjusting for confounders. (biomedcentral.com)
  • High burden of chronic cardio-metabolic disorders including type 2 diabetes mellitus (T2DM), chronic kidney disease (CKD), and cardiovascular disease (CVD) have been reported in the Middle East and North Africa region. (biomedcentral.com)
  • We aimed to externally validate a non-laboratory risk assessment tool for the prediction of the chronic cardio-metabolic disorders in the Iranian population. (biomedcentral.com)
  • This model showed acceptable discrimination and good calibration for risk prediction of chronic cardio-metabolic disorders in short and long-term follow-up in the Iranian population. (biomedcentral.com)
  • Chronic cardio-metabolic disorders including type 2 diabetes mellitus (T2DM), chronic kidney disease (CKD), and cardiovascular disease (CVD) have a considerably higher overall disability-adjusted life years (DALYs) in the Middle East and North Africa region (MENA) compared to their global estimates. (biomedcentral.com)
  • 10 ] suggest in a recent article that the best approach for screening cardio-metabolic disease is to start from non-laboratory measures in the primary phase and employ laboratory measures only for the high-risk group of individuals. (biomedcentral.com)
  • interval 2.5 to 4.0) per 1000 person years among and Public Health, University Design the group with poor cardiovascular health, the College London, London, UK absolute rate differences per 1000 person years 3 Prospective cohort study. (readkong.com)
  • Sabia S, Fayosse A, Dumurgier J, Dugravot A, Akbaraly T, Britton A, Kivimäki M, Singh-Manoux A. Alcohol consumption and risk of dementia: 23 year follow-up of Whitehall II cohort study. (alcoholresearchforum.org)
  • The breaking research is revealing a number of roles for vitamin K reaching well beyond coagulation to not only long term cardiovascular and skeletal health, but that of the brain and nervous system, and also for insulin production and sensitivity, and genomic stability / cancer prevention. (vitamindwiki.com)
  • Few differences in risk markers were found between patients with mild, moderate and severe depression, and no interaction occurred between depression severity and CRF. (frontiersin.org)
  • Although several mechanisms underlying this relationship have been proposed, understanding the associations between the omega-3 index and markers of CVD in the community can shed additional light on this question. (nih.gov)
  • A screening strategy for calculating cardiovascular risk that uses multiple non-laboratory-based risk markers performed as well as approaches based on Framingham risk scores, which use cholesterol measurements in all patients. (medscape.com)
  • An artificial intelligence-based prognostic prediction model for hemorrhagic stroke. (cdc.gov)
  • The K-CVD model showed excellent discrimination and calibration in Koreans. (bvsalud.org)
  • For external validation of the model in the Tehran lipids and glucose study (TLGS), the Area under the curve (AUC) and the Hosmer-Lemeshow (HL) goodness of fit test were performed for discrimination and calibration, respectively. (biomedcentral.com)
  • Moreover, adding data of educational levels and marital status did not improve, the discrimination and calibration in the enhanced model. (biomedcentral.com)
  • Abstinence in midlife was associated with a higher risk of dementia (hazard ratio 1.47, 95% confidence interval 1.15 to 1.89) compared with consumption of 1-14 units/week. (alcoholresearchforum.org)
  • Analysis using multistate models suggested that the excess risk of dementia associated with abstinence in midlife was partly explained by cardiometabolic disease over the follow-up as the hazard ratio of dementia in abstainers without cardiometabolic disease was 1.33 (0.88 to 2.02) compared with 1.47 (1.15 to 1.89) in the entire population. (alcoholresearchforum.org)
  • In this study, we introduce a cardiovascular disease (CVD) policy model which can be used to model remaining life expectancy including a measure of socioeconomic deprivation as an independent risk factor for CVD. (bmj.com)
  • Combinatorial Use of Machine Learning and Logistic Regression for Predicting Carotid Plaque Risk Among 5.4 Million Adults With Fatty Liver Disease Receiving Health Check-Ups: Population-Based Cross-Sectional Study. (cdc.gov)
  • The purpose of this study was to contribute to the knowledge regarding the penetrance of internet and mobile technologies, such as cellphones or smartphones in existing large cohort studies of cardiovascular disease. (jmir.org)
  • The study endpoint was the first occurrence or recurrence of CVD. (biomedcentral.com)
  • The present study provides important information on the association of alcohol and dementia by following a large cohort of British civil servants over a mean period of 23 years, with repeated assessments of alcohol consumption. (alcoholresearchforum.org)
  • Red blood cell (RBC) levels of eicosapentaenoic acid (EPA) plus docosahexaenoic acid (DHA, the omega-3 index, expressed as a percent of total fatty acids) are inversely related to risk for cardiovascular disease (CVD). (nih.gov)
  • Dietary recommendations to decrease the risk of cardiovascular disease (CVD) have focused on reducing intake of saturated fatty acids (SFA) for more than 50 years. (preprints.org)
  • Based on these data, an individual's 10-year CVD risk was calculated according to Framingham CVD risk models and translated into a Heart Age. (jmir.org)
  • This population-based risk prediction tool would help to appropriately identify high-risk individuals and provide preventive interventions in the Korean population. (bvsalud.org)
  • Individuals start in a CVD-free state and can transit to three CVD event states plus a non-CVD death state. (bmj.com)
  • Unfortunately, many individuals with CVD remain undiagnosed until life-threatening events occur. (biomedcentral.com)
  • Cardiorespiratory fitness and long-term survival in "low-risk" adults. (jamanetwork.com)
  • The model showed acceptable discrimination, with an AUC of 0.72 (95% CI 0.69-0.75) for men and 0.73 (95% CI 0.71-0.76) for women. (biomedcentral.com)
  • Eleven percent ( n = 53) of clients were found with moderate/high CVD risk, of whom almost one-third were under 35 years ( n = 16). (frontiersin.org)
  • Most studies also suggest that moderate drinkers tend to have a lower risk of developing dementia, including Alzheimer disease. (alcoholresearchforum.org)
  • The main results indicate that abstinence in middle life is associated with a significantly higher risk of dementia than the risk among moderate drinkers, while subjects reporting the intake of larger amounts of alcohol or evidence of an alcohol use disorder are at increased risk of dementia. (alcoholresearchforum.org)
  • CDC pooled results for those years to cardiovascular health of this population ( 5 ). (cdc.gov)
  • Patients with rheumatoid arthritis (RA) and other inflammatory joint disorders (IJD) have increased cardiovascular disease (CVD) risk compared with the general population. (bmj.com)
  • In general, our model predictions were comparable with observed event rates for a Scottish randomised statin trial population which has an overlapping follow-up period with SHHEC. (bmj.com)
  • Development and validation of an interpretable machine learning model-Predicting mild cognitive impairment in a high-risk stroke population. (cdc.gov)
  • T2DM, CKD, and CVD) in the Dutch population. (biomedcentral.com)
  • Subpopulation analysis showed that the impact of feature design had a more significant effect on model accuracy than the population size. (jmir.org)
  • We demonstrated that accurate risk prediction of CHD from EHRs is possible given a sufficiently large population of training data. (jmir.org)
  • Overall, predicted CVD risk is low in this population. (sajhivmed.org.za)
  • Depression and CVD risk are pre- valent, modifiable conditions that warrant population-level intervention. (cdc.gov)
  • Unipolar depression is observed in 7% of the US adult population for CVD risk. (cdc.gov)
  • Objectives A policy model is a model that can evaluate the effectiveness and cost-effectiveness of interventions and inform policy decisions. (bmj.com)
  • Furthermore, the model performance was compared with the Framingham risk score (FRS) and pooled cohort equation (PCE). (bvsalud.org)
  • We constructed 10-year general cardiometabolic risk score functions and evaluated its predictive performance in 2012-2013. (cdc.gov)
  • Social bias in artificial intelligence algorithms designed to improve cardiovascular risk assessment relative to the Framingham Risk Score: a protocol for a systematic review. (cdc.gov)
  • increment in the cardiovascular health score). (readkong.com)
  • The cardiovascular health score was and dementia was also seen in people who remained (or @epiageing on Twitter the sum of seven metrics (score range 0-14) and was free of cardiovascular disease over the follow-up orcid 0000-0003-3109-9720) categorised into poor (scores 0-6), intermediate (7-11), (hazard ratio 0.89 (0.84 to 0.95) per 1 point increment Additional material is published and optimal (12-14) cardiovascular health. (readkong.com)
  • in the cardiovascular health score). (readkong.com)
  • The additive net reclassification improvement (NRI) was 21.8%, and the absolute NRI was 2.0% by addition of RNFL thickness over the Framingham risk score. (biomedcentral.com)
  • There was no significant difference between the multistage approach and the Framingham risk score approach in discriminating risk. (medscape.com)
  • The Korean atherosclerotic cardiovas cular disease risk prediction (K-CVD) model was developed separately for men and women using the development dataset and validated in the validation dataset. (bvsalud.org)
  • It is not clear if each of these different measures of BA captures unique information or adds complementary information over and above chronological age (CA) to predict disease risk and life span. (deepdyve.com)
  • 2005-2018 National Health and Nutrition Examination Survey for Cardiovascular Disease Risk Among US Adults, National Health adults aged 20 to 39 years (n = 10,588) and adults aged 40 to 79 and Nutrition Examination Survey, 2005-2018. (cdc.gov)
  • RESULTS: HbA1c was significantly related to general CVD risk. (cdc.gov)
  • Compared to D:A:D 2010, CVD risk estimated by the FHS-CVD model showed similar overall results for risk classification. (sajhivmed.org.za)
  • Lifestyle interventions targeting healthy diet and/or physical activity are recommended as a physically active and healthy lifestyle contributes equally to patients' mental well-being and cardiovascular health. (frontiersin.org)
  • This highlights that Web-based self-assessment health tools can be a useful means to interact with people who are at risk of developing disease, but where interventions are still viable. (jmir.org)
  • Web-Based Self-Assessment Health Tools: Who Are the Users and What Is the Impact of Missing Input Information? (jmir.org)
  • Missing information in the self-assessment health tools was shown to result in inaccurate self-health assessments. (jmir.org)
  • Around one-fifth of the health disparity is caused by cardiovascular disease (CVD). (frontiersin.org)
  • Despite the importance of absolute cardiovascular risk assessment (CVRA) as a screening and early intervention tool, few studies have reported its use within the Australian Indigenous primary health care (PHC) sector. (frontiersin.org)
  • RESEARCH Association of ideal cardiovascular health at age 50 with BMJ: first published as 10.1136/bmj.l4414 on 7 August 2019. (readkong.com)
  • Paris, France optimal cardiovascular health. (readkong.com)
  • The Helsinki, Finland cholesterol, blood pressure) metrics, coded on a three association between cardiovascular health at age 50 Correspondence to: S Sabia [email protected] point scale (0, 1, 2). (readkong.com)
  • RNFL thinning was independently associated with increased incident cardiovascular risk and improved reclassification capability, indicating RNFL thickness derived from the non-invasive OCT as a potential retinal fingerprint for CVD event across ethnicities and health conditions. (biomedcentral.com)
  • Using OCT, alterations of retinal nerve fiber layer (RNFL) thickness have been implicated in cardiovascular health, generating new insights into the role of retinal fingerprints in the prediction of CVD. (biomedcentral.com)
  • Predictions of cardiovascular disease risks based on health records have long attracted broad research interests. (jmir.org)
  • Although new approaches for data collection, such as mobile technology and teleresearch, have demonstrated new opportunities for the conduct of more timely and less costly surveys in community-based studies, literature on the feasibility of conducing cardiovascular disease research using mobile health (mHealth) platforms among middle-aged and older African Americans has been limited. (jmir.org)