• Genes
  • The Programmed Ribosomal Frameshift Database (PRFdb) provides an interface to help researchers identify potential programmed -1 ribosomal frameshift (-1 PRF) signals in eukaryotic genes or sequences of interest. (biomedcentral.com)
  • ribosome
  • Complementary to single-molecule techniques, computational modeling provides insights into global motions of the ribosome, whose structural transitions during frameshifting have not yet been elucidated in atomic detail. (hindawi.com)
  • frame
  • Here we will test the hypothesis that dysregulation of programmed -1 ribosomal frame shifting affects the expression of specific subsets of genes and that when deregulated may contribute to disease pathogenesis. (grantome.com)