Due to broader coverage and high sensitivity for insertions and deletions, sequencing via MAPs afforded important detection of additional actionable mutations. (nature.com)
The antigens tested showed high sensitivity (87.5%) and specificity (100%) with 95% confidence interval (0.505-0.995) for optimal threshold, except antigen D which showed 50% (0.217-0.783) sensitivity (95% CI) and 100% (0.380-1.000) specificity (95% CI). (cdc.gov)
Taken together, this study provides a panel of critical antigens with high sensitivity and specificity for the needed discrimination between HP patients and healthy subjects and paves the way for developing future immunodiagnostic tools for occupational HP. (cdc.gov)
Although these markers provide relatively high sensitivity and specificity for early disease detection, they are not suitable for monitor of disease progression. (datadryad.org)
Ejection fraction9
Recent advances in three-dimensional (3D) TTE allow automated detection of endomyocardial borders for accurate assessment of ventricular volumes and ejection fraction. (medscape.com)
CMR is considered the gold standard for assessing chamber volumes and LV and right ventricular (RV) ejection fraction. (medscape.com)
Present indications for primary ICD placement, which are based on the presence of LVEF [left ventricular ejection fraction] ≤35% and heart failure symptomatology, appear to lack sensitivity and specificity for predicting sudden cardiac death risk," says Dr. Narins. (medpagetoday.com)
103 had heart failure with reduced ejection fraction (HFREF) and 73 had heart failure with preserved ejection fraction (HFPEF). (bmj.com)
What is 'normal' left ventricular ejection fraction? (techmed.sk)
5 Additionally, multiple studies have shown strong interrater agreement between Emergency Medicine physicians and cardiologists in the diagnosis of reduced left-ventricular ejection fraction using POC TTE. (acep.org)
13 In another study, Emergency Medicine trainees with limited POC TTE experience who performed a short course that incorporated both online and in-person training showed high interrater agreement with cardiologists in their assessment of left ventricular function, left ventricular ejection fraction by M-mode, detection of pericardial effusion and IVC diameter assessment. (acep.org)
LGE burden on CMR can also help identify CS patients without severe decline in ejection fraction where ICD placement is recommended for primary prevention of sudden cardiac death. (asnc.org)
Other common indications are evaluation of gallbladder ejection fraction (as an indicator of chronic cholecystitis), bile leak, and biliary atresia [1] . (radiologykey.com)
Assay3
What's really nice about [this] is that it really highlights the value of the sensitivity around the Radar assay compared to what is typically done … or is planned to be used from some of our competition," Sikri said. (genomeweb.com)
The purified antigen fractions were subjected to enzyme-linked immunosorbant assay (ELISA) to determine their reactivity. (pasteur.fr)
We created and characterized BAL fluid pools from non-EVALI individuals to determine assay accuracy, precision, linearity, limits of detection, and analytical specificity. (cdc.gov)
Detection5
Also, we sought to improve the sensitivity of obesogen detection/validation methods to establish a framework for post-toxicological chemical assessment. (nist.gov)
5C-ID reduces spatial noise and enables higher resolution 3D genome folding maps than canonical 5C, allowing for a marked improvement in sensitivity and specificity of loop detection. (biorxiv.org)
Most assays, such as immunoassay, utilise the distinct protease resistance property of PrP d by digesting samples with proteinase K, which increases the specificity and sensitivity of PrP d detection. (biomedcentral.com)
Due to these challenges, the sensitivity and specificity toward error detection has been limited, and IVD has mainly been restricted to detection of gross errors. (dtu.dk)
Negatives2
It is created by plotting the fraction of true positives out of the positives (TPR = true positive rate) vs. the fraction of false positives out of the negatives (FPR = false positive rate), at various threshold settings. (chicagoboyz.net)
Specificity represents fraction of true negatives. (ki.si)
Diagnosis3
2,3 While a positive cardiac Gallium-67 scan is also one of the imaging criteria for diagnosis, it has poor sensitivity and has been replaced by FDG PET. (asnc.org)
The inclusion of AVDSf in combination with other scoring systems that evaluate clinical likelihood of PE and D-dimer levels result in higher sensitivity and specificity rates for the diagnosis of PE. (capnography.com)
In a retrospective study from 1980, the sensitivity and specificity of haptoglobin in the diagnosis of hemolytic anemia was 83% and 96%, respectively. (medscape.com)
Analytical1
For less than a tenth of the cost and a fraction of the size of traditional NMR systems, WaveGuide Formµla™ enables on-the-spot analysis of almost any substance without sacrificing analytical sensitivity or specificity. (cambridgeconsultants.com)
Ventricular1
Contrast-enhanced T1 mapping is mostly used for calculating extracellular volume fraction (ECV) - that is, the ratio of pre- and postcontrast myocardial T1 to that of the ventricular blood compartment T1. (medscape.com)
Diagnostic2
Nous avons élaboré une version en langue arabe de ce questionnaire et avons testé sa fiabilité et sa validité concurrente et discriminante en tant qu'outil diagnostic d'un trouble dépressif majeur. (who.int)
The authors evaluated the diagnostic contribution of alveolar dead space fraction (AVDSf) measured using capnography in patients admitted with suspected pulmonary embolism (PE). (capnography.com)
Assays1
Results: Serum-free conditions greatly enhanced sensitivity without reducing specificity in ligand binding assays. (nist.gov)
Increases1
Adjusting a cutoff point to identify more patients with disease (increase test sensitivity) also increases the number of false positives (poor specificity), and moving the cutoff point the other way to avoid falsely diagnosing patients as having disease increases the number of false negatives. (msdmanuals.com)
Proteins1
Our initial immunoproteomic study had identified 33 immuno-reactive proteins from different fractions of the cell. (cdc.gov)
Clinical3
In the other study, fexofenadine was administered with grapefruit juice, with or 2 h before aqueous suspension of the particulate fraction of juice containing known clinical inhibitors of enteric CYP3A4, but relatively low naringin concentration (34 microM), or with water. (nih.gov)
Naringin appears to have sufficient safety, specificity, and sensitivity to be a clinical OATP1A2 inhibitor probe. (nih.gov)
These studies offer specialized testing in specific clinical situations, and in some cases have higher sensitivity, specificity, and accuracy compared to other modalities. (radiologykey.com)
Antigen2
H1, the purified antigen fraction of the heat-extracted preparation, was found to be the most reactive and specific of all fractions tested. (pasteur.fr)
The specificity and sensitivity of in-house ELISA using the H1 antigen were found to be 93.3 and 85.0%, respectively. (pasteur.fr)
Optimal1
Sensitivity and specificity at optimal cut-offs were determined separately for enhancing and non-enhancing lesions. (regionh.dk)
Small fraction2
2 ] Thus, official case reporting may tend to encompass a high fraction of severe cases but only a small fraction of asymptomatic or mildly symptomatic cases. (medrxiv.org)
Since this is not practical and since this group is only a small fraction of the subjects tested (~0.05%), the cleanest approach to analyzing the data is to exclude them. (cdc.gov)
Biopsy2
Sensitivity of endomyocardial biopsy is low, around 25%, mainly due to patchy nature of disease along with technical factors. (asnc.org)
6,7 In a study of 321 patients with biopsy proven CS, CMR had a sensitivity of 97% and a specificity of 99% to diagnose CS. (asnc.org)
States that wish to improve the specificity of reporting may find the definitions helpful. (cdc.gov)
Accuracy1
I also have the specificity and accuracy values, would that help me at all? (stackexchange.com)
Protein1
Haptoglobin is a colorless protein of the alpha-globulin fraction of human serum. (medscape.com)
Patients4
RÉSUMÉ La prévalence de la maladie cœliaque chez des patients atteints d'hypothyroïdie auto-immune n'a pas été étudiée auparavant en Jordanie, ni dans d'autres pays arabes. (who.int)
Un examen transversal à partir des dossiers de tous les patients adultes atteints d'hypothyroïdie auto-immune qui avaient consulté un centre d'orientation en Jordanie au cours d'une période de huit mois a été mené. (who.int)
Only the reactive fractions were tested for specificity by ELISA by allowing the fractions to react with positive sera of patients with non-leptospiral illness. (pasteur.fr)
We report a clear association between the EpCAM-positive CTC-fraction and ctDNA for SOX17 promoter methylation both for patients with early ( P = 0.001) and metastatic breast cancer ( P = 0.046) but not for CST6 and BRMS1. (oncotarget.com)
Precision2
In some cases, Mirinho is even better in terms of sensitivity or precision. (biomedcentral.com)
We provide a simpler and much faster method with very reasonable sensitivity and precision, which can be applied without special adaptation to the prediction of both animal and plant pre-miRNAs, using as input either genomic sequences or sRNA-seq data. (biomedcentral.com)
Typically1
Although the impact of potential errors may be detrimental since treatments are typically administered in large fractions and with high-gradient-dose-distributions, BT is usually delivered without independent verification of the treatment delivery. (dtu.dk)
Negative1
TPR is also known as sensitivity, and FPR is one minus the specificity or true negative rate. (chicagoboyz.net)
Positive predi1
Why) Does positive predictive value depend on sensitivity? (stackexchange.com)
Terms1
Reservoir size and dynamics have been estimated by a variety of different methods, all with their own advantages and disadvantages in terms of speed, throughput, sensitivity, and specificity to rebound-competent sequences. (nature.com)
Data1
The researchers manually extracted data on oxygen saturations and fraction of inspired oxygen (FiO2), and four oxygen variables were calculated on a weekly basis. (aao.org)
Cost1
5C-ID enables the creation of high-resolution, high-coverage maps of chromatin loops in up to a 30 Megabase subset of the genome at a fraction of the cost of Hi-C. (biorxiv.org)
A total of forty two extracts, one fraction and two pure compounds were tested in the in vitro system and thirty extracts gave Positive results. (who.int)
Water2
Solid-phase extraction (SPE) was used to fractionate DWH oil COREXIT water accommodated fraction (CWAF). (nist.gov)
From SPE, the 50:50 ethanol:water fraction of CWAF contained obesogen(s) and LC-MS indicated major components of COREXIT were present in this fraction. (nist.gov)
Total2
Even if you know the total population this sensitivity was calculated in, the answer is still no. (stackexchange.com)
These formulas give a fraction, which you'll then have to multiply with the total population to get the exact TP and TN values. (stackexchange.com)