These mathematical models will be modified and used to maximize therapeutic gain in MMR − tumors versus MMR + normal tissues by predicting the optimal dose of IUdR and optimal timing for IR treatment to increase the synergistic action using xenograft models and, later, in clinical trials. (aacrjournals.org)
Chimeric Antigen Receptor (CAR) T cells are now standard of care (SOC) for some patients with B cell and plasma cell malignancies and could disrupt the therapeutic landscape of solid tumors. (biomedcentral.com)
Relies1
Alternative residential programs for opioid use disorder include the more traditional Therapeutic Community (TC) program which relies on the effects of the socialisation within a group in a residential setting as the main agent of therapy and change [ 2 ]. (biomedcentral.com)
Treatments2
Surgical suture made up of polyglycolic acid is widely used for surgical procedures and therapeutic treatments in the field of ophthalmic, gynecological and obstetric, orthopedic, urological and other departments of the medical industry. (marketsandmarkets.com)
CQC registered Medical Skin & Cosmetic treatment clinic in Birmingham Mailbox Expert clinicians specialising in non surgical rejuvenation and anti ageing medicine with treatments that include Frac. (consultingroom.com)
Practical Approach1
Diabetes care: therapeutic inertia in doctors and patients Getting Patients to Their Lipid Targets: A Practical Approach to Implementing Therapeutic Lifestyle Changes Is blood pressure control to less than 140/less than 90 mmHg in 50% of all hypertensive patients as good as we can do in the USA: or is this as good as it gets? (wikipedia.org)
Diagnostic1
We offer a broad range of diagnostic and therapeutic procedures, providing patients with unparalleled service. (dulyhealthandcare.com)
Approach1
Drug repurposing is an approach that holds promise for identifying new therapeutic uses for existing drugs. (biomedcentral.com)
Targets1
So, making the drug more hydrophilic while it retains the adequate binding affinity to therapeutic protein targets is advisable. (vedantu.com)
Resistance3
Therapeutic inertia (also known as clinical inertia) is a measurement of the resistance to therapeutic treatment for an existing medical condition. (wikipedia.org)
In order to fight effectively against this bacterial resistance and to limit the cases of therapeutic failures, the search for new, more efficient molecules capable of effectively eradicating the mutant strains responsible for bacterial diseases must be encouraged (Brochot et al. (springeropen.com)
The identification of drug-resistant patients and the development of new therapeutic strategies capable of overcoming drug resistance are therefore two major challenges. (springeropen.com)
Intervention1
Both feedback reporting processes and intervention studies aimed at reducing therapeutic inertia have been shown to increase control of hypertension, diabetes, and hyperlipidemia. (wikipedia.org)
Patients4
The therapeutic effectiveness is expected to be higher for those patients with natal or early onset of the disorder, and at a younger age when they receive the therapy. (biomedcentral.com)
The study result helps to formulate an ideal regimen for ASD patients and allow therapists and parents to make appropriate expectation towards the therapeutic outcome of acupuncture. (biomedcentral.com)
This reduces the complexity of cell manufacturing and increase the ease with which the therapeutic cells can be make the product for patients. (t4gip.com)
The direct impact of these practices is to reduce the therapeutic potential of the drugs available to treat patients with bacterial infection (Cristóbal-Azkarate et al. (springeropen.com)
Onset3
The influence on the therapeutic effect by factors including chorological age and onset pattern were further taken into consideration and analyzed. (biomedcentral.com)
Despite the advantages of acupuncture therapy on ASD children was demonstrated in previous studies, no investigations has currently been made on how age and onset type of ASD influence the therapeutic effect of acupuncture treatment. (biomedcentral.com)
The delayed onset of an- bFacultad de Medicina, Universidad de Chile, Santiago, Chile tidepressant action suggests that plastic changes over cLaboratorio de Neurobiologia y Conducta, Facultad de Medicina, protracted periods of time might be causally related to the Universidad Catolica del Norte, Santiago, Chile therapeutic effect. (health-articles.net)
Risk1
2019 ). This fact may be associated with a risk of exhaustion of therapeutic remedies capable of treating diseases caused by those mutant strains. (springeropen.com)
Potential3
Silver (Ag) nanoparticles have high therapeutic potential and exhibit good antimicrobial activity. (springer.com)
The lengthy process and exorbitant cost of drug discovery have led researchers to explore the possibility of drug repositioning or drug repurposing (DR), i.e., investigating the potential therapeutic uses of existing medications beyond their original intended purpose. (biomedcentral.com)
These examples demonstrate the potential of DR to uncover new therapeutic uses for existing medications, which can lead to improve patient outcomes and reduce healthcare costs. (biomedcentral.com)
Effect2
Therapeutic window is the dosage range within which the drug is effective (i.e., the dose at which the drug produces the desired effect) without causing toxicity. (lecturio.com)
A level lower than this range may not have the desired therapeutic effect. (lecturio.com)
Population1
Therapeutic index is calculated by dividing the toxic dose for 50% of the population by the minimum effective dose for 50% of the population. (lecturio.com)
Disease1
The goal of DR as a computational problem is to detect whether a given drug and disease pair has a therapeutic association. (biomedcentral.com)
Medicine1
The therapeutic properties of honey, once considered a form of folk or preventive medicine, are acquiring importance for the treatment of acute and chronic free radical-mediated diseases (atherosclerosis, diabetes and cancer). (researchgate.net)
Total2
It is commonly measured as a percentage of the number of encounters in which a patient with a condition received new or increased therapeutic treatment out of the total number of visits to a health care professional by the patient. (wikipedia.org)
In Dr. Okonofua's original paper, this patient's therapeutic inertia is calculated as h v − c v {\displaystyle {\frac {h}{v}}-{\frac {c}{v}}} where h is the number of visits with an uncontrolled condition, c is the number of visits in which a change was made, and v is the total number of visits. (wikipedia.org)
There are two common methods used in calculating therapeutic inertia. (wikipedia.org)
Drug1
AppliedVR, a pioneer advancing the next generation of immersive therapeutics, today announced that the U.S. Food and Drug Administration (FDA) has granted de novo approval for its flagship immersive therapeutic, EaseVRx, to treat chronic low back pain, which previously received breakthrough device designation in 2020. (chemrobotics.in)
Studies2
Retrospective studies have highlighted several examples of drugs that have been successfully repurposed for new therapeutic uses. (biomedcentral.com)
This frac networking persists what studies use not public at America's own edition and book aliases and has you with the businesses to buy in any review. (quietisolation.de)
Significant1
Here, we define a GTP-mediated signaling cascade that links metabolism to DNA repair and has significant therapeutic implications. (bvsalud.org)
Demand2
The increasing demand for polyglycolic acid in biodegradable frac ball and plug manufacturing is the primary factor driving the market demand. (marketsandmarkets.com)
Additional fully non-viral CRISPR knock-in platforms are needed to ensure adequate access to meet the increasing demand for engineered T cells for therapeutic use. (biomedcentral.com)