• The rates of appearance (Ra) and disappearance (Rd) of glycerol and free fatty acids (FFAs) were determined using [1,1,2,3,3-2H]glycerol and [1-13C]palmitate, respectively, whereas the overall rate of fatty acid oxidation was determined using indirect calorimetry. (bullshido.net)
  • Enoyl-CoA isomerase is involved in the beta-oxidation, one of the most frequently used pathways in fatty acid degradation, of unsaturated fatty acids with double bonds at odd-numbered carbon positions. (wikipedia.org)
  • As it functions in the step immediately preceding the actual beta-oxidation and forms a double bond extending from the beta-carbon (position 2), enoyl-CoA isomerase is involved in both the NADPH-dependent and NADPH-independent pathways of beta-oxidation. (wikipedia.org)
  • The effects of metformin on blood glucose has been explained through reduced hepatic gluconeogenesis and increased glucose uptake in skeletal muscles ( 3 , 4 ). (aacrjournals.org)
  • Vitamin E is found only in fatty foods like oils and nuts. (clinicaltrials.gov)
  • Enoyl-CoA-(∆) isomerase, also known as dodecenoyl-CoA-(∆) isomerase, 3,2-trans-enoyl-CoA isomerase, ∆3(cis),∆2(trans)-enoyl-CoA isomerase, or acetylene-allene isomerase, (EC 5.3.3.8) is an enzyme that catalyzes the conversion of cis-or trans-double bonds of fatty acids at gamma-carbon (position 3) to trans double bonds at beta-carbon (position 2). (wikipedia.org)
  • Since the key step in the degradation of fatty acids with double bonds at even-numbered carbon positions also produces 3-trans-enoyl-CoA in mammals and yeasts, enoyl-CoA isomerase is technically required for their metabolism as well. (wikipedia.org)
  • When training is superimposed to HFD, the most prominent finding provided by this study is that the diet-induced effects are cumulative with the well-known training effect on VO2max, exercise endurance, oxidative capacity of red muscle, and metabolic responses to exercise, with a further reduction in liver glycogen breakdown. (bullshido.net)
  • In an immunoblot, antibodies were run against all enoyl CoA isomerase. (wikipedia.org)
  • Therefore, we need to seek better strategies for the treatment of cardiac hypertrophy ( 3 - 5 ). (frontiersin.org)
  • Therefore, the primary objective of the present study was to find the role of TLR4 in cardiac hypertrophy and the molecular mechanism thereof. (frontiersin.org)
  • We found nuclear localization of HIF1 alpha and increased expression of VEGF, BNIP3 and GLUT1 in a chromophobe carcinoma from a Birt-Hogg-Dube patient. (dundee.ac.uk)
  • RESEARCH DESIGN AND METHODS Wild-type and Nur77 null mice were fed a high-fat diet (60% calories from fat) for 3 months. (diabetesjournals.org)
  • If available, the SCOP 1.75 domain assignment [ 3 ] is used. (rcsb.org)
  • Although these receptors possess a putative ligand-binding domain, X-ray crystallography studies suggest that the ligand-binding pocket is occluded by bulky hydrophobic residues and is unable to accommodate ligands ( 2 , 3 ). (diabetesjournals.org)
  • The multifunctional enzymes are found in bacteria and in the peroxisomes of some eukaryotes, but they serve two functions: the N-terminal domain works the same as the other classes of enoyl-CoA isomerases and the C-terminal domain works as a dehydrogenase, specifically, to 3-hydroxyactyl-CoA. (wikipedia.org)
  • Less than 0.1% of children who took aspirin developed Reye syndrome, but more than 80% of patients diagnosed with Reye syndrome had taken aspirin in the past 3 weeks. (medscape.com)
  • The goal of EHDI is to assure that permanent hearing loss is identified before 3 months of age, appropriate and timely intervention services are provided before 6 months of age, families of infants with hearing loss receive culturally competent support, and tracking and data management systems for newborn hearing screens are linked with other relevant public health information systems. (thefreedictionary.com)