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  • C57BL
  • Third, in a senior high school science research project carried out in part in our laboratory, a commercial green tea extract that was fed to aging C57BL/6 mice delayed collagen cross-linking and fluorescent advanced glycation end product (AGE) accumulation by a mechanism that was duplicated by the combination of vitamins C and E ( 3 ). (diabetesjournals.org)
  • We evaluated the safety of T-AG17 and its effects on physiological and molecular metabolic parameters including hormonal profile, glucose levels, adipogenesis and adipocyte hypertrophy in a diet-induced obesity model using C57BL/6 mice. (deepdyve.com)
  • mitochondria
  • Here we describe a fluorometric assay that allows for a comprehensive characterization of mtPTP opening in isolated mouse heart mitochondria. (jove.com)
  • Here researchers show that calorie restriction appears to boost the rate at which new mitochondria are spawned: "mice with increased respiratory rates and reduced energetic conversion efficiency due to spontaneously uncoupled mitochondria lived longer than their counterparts. (fightaging.org)
  • murine
  • Due to the partial genetic homology between mouse chromosome 16 and human chromosome 21, murine trisomy 16 is considered a model for both DS and AD (Galdzicki and Siarey, 2003). (conicyt.cl)
  • antibodies
  • 1. A continuous cell line which produces human anti-exotixin antibodies, comprising: a stable fused cell hybrid of a human peripheral blood lymphocyte immunized by a toxin, or an imunogenic fragment thereof, or a toxoid prepared from an exotoxin, or an immunogenic fragment thereof, and a mouse myeloma cell, in which the antibodies are capable of neutralizing exotoxin. (freepatentsonline.com)
  • 3. A continuous cell line which produces human anit-tetanus toxin antibodies, comprising: a stable fused cell hybrid of a tetanus toxin-immunized or toxoid-immunized human peripheral blood lymphocyte and a mouse myeloma cell, in which the anitbodies are capable of neutralizing tetanus toxin. (freepatentsonline.com)
  • beneficial
  • This implies that adequate provision of polyunsaturated fatty acids and co-factors needed for their metabolism, and efforts to enhance the formation of their beneficial metabolites PGE 1 , PGI 2 , PGI 3 , lipoxins, resolvins, protectins, maresins and nitrolipids could form a novel approach in the prevention and management of these diseases in this high-risk population. (biomedcentral.com)
  • cold
  • Cold exposure (CE) up-regulates circulating fibroblast growth factor 21 (FGF21) in people by 37% , and FGF21 in mice BAT by a factor of 40x . (longecity.org)
  • weight
  • Feeding metformin in pharmacologically relevant doses to mice on a high fat diet normalized HbA1c levels and ameliorated glucose tolerance, as expected, but also considerably slowed down weight gain. (diabetestalk.net)
  • diet
  • Mice on a high fat diet were continuously fed metformin in a therapeutically relevant dose, mimicking a retarded formulation. (diabetestalk.net)
  • activation
  • At present, there is no question that apoptosis requires energy, because it is a highly regulated process involving a number of ATP-dependent steps, such as caspase activation, enzymatic hydrolysis of macromolecules, chromatin condensation, blebs formation, and apoptotic body formation ( 6 - 12 ). (pnas.org)