Furthermore the transcription elements CCAAT/enhancer-binding proteins α (C/EBPα) and STAT3 had been found to be engaged in the essential positive transcriptional legislation of ITGB6 in OSCC cells. (researchatlanta.org)
CCAAT/enhancer binding proteins (C/EBPs) are a family of leucine zipper, transcription factors that bind to DNA as homodimers and heterodimers. (johnshopkins.edu)
Zahnow, CA 2002, ' CCAAT/enhancer binding proteins in normal mammary development and breast cancer ', Breast Cancer Research , vol. 4, no. 3, pp. 113-121. (johnshopkins.edu)
Proteins to form2
p100 and p105 can however undergo limited proteolysis to generate p52 and p50, respectively, which can form heterodimers with Rel proteins to form transcriptional activators [ 5 ]. (oncotarget.com)
The mutated proteins can interact with normal proteins to form dysfunctional tetramers, and thus change the pattern of genome methylation ( 5 ). (frontiersin.org)
Homology1
This family of proteins comprises two subfamilies that share a DNA-binding and dimerization domain called the Rel homology domain (RHD) [ 4 ] and form homo- or hetero- dimers. (oncotarget.com)
Regulate1
Rel frequently combines with other related proteins (NF-KAPPA B, I-kappa B, relA) to form heterodimers that regulate transcription. (childrensmercy.org)
Motifs1
DNA-binding motifs formed from two alpha-helixes which intertwine for about eight turns into a coiled coil and then bifurcate to form Y shaped structures. (lookformedical.com)
Leucine1
An enzyme that catalyzes the first step in the biosynthetic pathway to LEUCINE , forming isopropyl malate from acetyl-CoA and alpha-ketoisovaleric acid. (lookformedical.com)
To date 18 and 8 subunits have been identified and are capable of forming more than 24 heterodimers that account for the structural and functional diversity of the integrin family [2]. (researchatlanta.org)
Twenty alpha-amino acids are the subunits which are polymerized to form proteins . (lookformedical.com)
Single2
Subunit of the heme-activated, glucose-repressed Hap2/3/4/5 CCAAT-binding complex - there should be a single motif for all four proteins, containing CCAAT. (utoronto.ca)
αvβ6 expression depends on integrin β6 (ITGB6) expression as ITGB6 only partners with αv forming a single heterodimer. (researchatlanta.org)
Delta2
CCAAT/enhancer-binding protein delta is a protein that in humans is encoded by the CEBPD gene. (wikipedia.org)
Binds DNA as a dimer and can form stable heterodimers with C/EBP delta. (lu.se)
Common form2
AML is a highly heterogeneous hematological disease and is the second most common form of leukemia. (mdpi.com)
Alzheimer's disease (AD) is the most common form of degenerative dementia, Bio Med Frontiers whose symptoms usually appear in the pre-senile age. (1elisakits.com)
Enhancer4
CCAAT/enhancer-binding protein delta is a protein that in humans is encoded by the CEBPD gene. (wikipedia.org)
CCAAT-enhancer binding protein alpha (C/EBP alpha) is a widely expressed 42 kDa basic-leucine zipper transcription factor that forms functional homodimers and heterodimers with C/EBP beta and gamma. (rndsystems.com)
This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. (nih.gov)
15. Ceramide, an apoptotic rheostat, inhibits CCAAT/enhancer binding protein-beta and NF-E2-related factor-2 activation: the role in glutathione S-transferase A2 gene repression. (nih.gov)
Proteins4
18. Human small Maf proteins form heterodimers with CNC family transcription factors and recognize the NF-E2 motif. (nih.gov)
It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. (affbiotech.com)
Circadian genes and the proteins produced by these genes constitute the molecular components of the circadian oscillator which form positive/negative feedback loops and generate circadian rhythms. (biomedcentral.com)
Homodimers1
The NF-κB complex consists of a number of structurally related subunits (p50, p52, RelA [also known as p65], RelB, and RelC), which can form heterodimers or homodimers. (medscape.com)
CEBP1
It can also form heterodimers with the related protein CEBP-alpha. (wikipedia.org)
Gene1
These RNPs( 10-20nm channel) have either timely to directly reduce into the cell and below, also linked from an cellular fibrillin must promote on the so-called stadium button of the transcription practice synaptic gene CCAAT. (erik-mill.de)
Promoter1
In proton-coupled membrane compartment, the salicylic transport reported by the other menu in the distinct synthesis enters bound into the synthase by a hemoglobin survival EPHBs was the major phone promoter forms 1 and 2, EAAT1 and EAAT2. (erik-mill.de)
Metabolism1
The span of viability of a cell characterized by the capacity to perform certain functions such as metabolism, growth, reproduction, some form of responsiveness, and adaptability. (lookformedical.com)
Cleavage1
Caspases are activated by proteolytic cleavage of a precursor form to yield large and small subunits that form the enzyme. (lookformedical.com)
Family1
The best characterized member of the NF-κB-family is the p50/p65 heterodimer, which consists of a p65 transactivation domain and a p50 DNA-binding domain. (medscape.com)
Beta1
The 4-aminobutyrate form beta-hydroxybutyrate yeast issue( ORC) is the pacemaker electron of phase beta and share of the cancer aka. (erik-mill.de)
Activity2
The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. (nih.gov)
13. Extracellular acidification enhances DNA binding activity of MafG-FosB heterodimer. (nih.gov)
Domain1
Two forms of CASP8 and FADD-like apoptosis regulating protein exist, a long form containing a caspase-like enzymatically inactive domain and a short form which lacks the caspase-like domain. (lookformedical.com)