Cell DifferentiationEmbryoid BodiesEmbryonic Stem CellsEmbryo, MammalianStem CellsTeratomaEndodermCell Culture TechniquesPluripotent Stem CellsCell LineageInduced Pluripotent Stem CellsOctamer Transcription Factor-3Germ LayersCell LineGene Expression Regulation, DevelopmentalCells, CulturedYolk SacCell AggregationBone Morphogenetic Protein 4Feeder CellsTotipotent Stem CellsCryoultramicrotomyFetal ProteinsMyocytes, CardiacPrimitive StreakMesodermStage-Specific Embryonic AntigensEmbryonic DevelopmentReverse Transcriptase Polymerase Chain ReactionGATA4 Transcription FactorHomeodomain ProteinsTretinoinChimeraLeukemia Inhibitory FactorBiological MarkersHematopoiesisBlastocystTeratocarcinomaHepatocyte Nuclear Factor 3-betaHematopoietic Stem CellsEctodermLamininTranscription FactorsOrganoidsKaryotypingHematopoiesis, ExtramedullaryEmbryonic and Fetal DevelopmentGreen Fluorescent ProteinsVisceraalpha-FetoproteinsGene ExpressionGene Expression ProfilingGerm CellsVascular Endothelial Growth Factor Receptor-2Cell ProliferationAntigens, CD31Coculture TechniquesImmunohistochemistrySOXB1 Transcription FactorsCulture Media, Serum-FreeNeural PlateNeovascularization, PhysiologicBlood VesselsTime FactorsFlow CytometryCell SeparationRNA, MessengerTissue EngineeringEmbryonic InductionSignal TransductionBone Morphogenetic ProteinsBasement MembraneKruppel-Like Transcription FactorsAntigens, CD15Carcinoma, EmbryonalGene Expression RegulationEndothelial CellsT-Box Domain ProteinsActivinsSpheroids, CellularNestinBone Morphogenetic Protein 2GATA6 Transcription FactorBioreactorsAlkaline Phosphatase