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MSX1 Transcription FactorTranscription FactorsForkhead Transcription FactorsTranscription, GeneticDNA-Binding ProteinsEnhancer Elements, GeneticMEF2 Transcription FactorsPromoter Regions, GeneticMyogenic Regulatory FactorsMolecular Sequence DataBase SequenceGene Expression RegulationSp1 Transcription FactorSignal TransductionBinding SitesTranscriptional ActivationTrans-ActivatorsNuclear ProteinsProtein BindingRNA, MessengerHomeodomain ProteinsCell LineGene Expression Regulation, DevelopmentalBasic Helix-Loop-Helix Transcription FactorsRepressor ProteinsProto-Oncogene ProteinsAmino Acid SequenceDNATranscription Factor AP-1TransfectionMutationCell NucleusGenes, ReporterCell DifferentiationLymphoid Enhancer-Binding Factor 1TCF Transcription FactorsProto-Oncogene Proteins c-aktCells, CulturedChromatin ImmunoprecipitationHeLa CellsBasic-Leucine Zipper Transcription FactorsMADS Domain ProteinsTranscription Factor AP-2Phosphatidylinositol 3-KinasesKruppel-Like Transcription FactorsRegulatory Sequences, Nucleic AcidTranscription Factors, TFIIReverse Transcriptase Polymerase Chain ReactionElectrophoretic Mobility Shift AssayYY1 Transcription FactorPlasmidsRecombinant Fusion ProteinsGATA4 Transcription FactorSTAT3 Transcription FactorNFATC Transcription FactorsCloning, MolecularPaired Box Transcription FactorsTranscription Factor TFIIDBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsGene ExpressionLuciferasesNF-kappa BActivating Transcription Factor 3Zinc FingersTranscription Initiation SiteSp3 Transcription FactorPhosphorylationMice, TransgenicProtein Structure, TertiaryGene Expression ProfilingActivating Transcription Factor 2ChromatinTranscription Factor TFIIBCell Line, TumorRNA Polymerase IIE2F1 Transcription FactorGATA1 Transcription FactorSequence Homology, Amino AcidGATA2 Transcription FactorGATA3 Transcription FactorGene Expression Regulation, FungalModels, BiologicalDown-RegulationMice, KnockoutBlotting, WesternTumor Cells, CulturedGATA Transcription FactorsTranscription Factor 7-Like 2 ProteinModels, GeneticMicrophthalmia-Associated Transcription FactorHelix-Loop-Helix MotifsActivating Transcription FactorsSequence AlignmentPhenotypeMice, Inbred C57BLSTAT1 Transcription FactorDrosophila ProteinsHistone DeacetylasesUp-RegulationOligonucleotide Array Sequence Analysis
MyogeninRegulatorsProteinPromotersProteinsTumorSignificantlyGrowthDevelopmentDataCommonCellInhibitMolecular weightExpression
Myogenin1
  • The Y-box protein MSY3/Csda represses myogenin transcription in skeletal muscle by binding a highly conserved cis-acting DNA element located just upstream of the myogenin minimal promoter (myogHCE). (biomedcentral.com)
Regulators2
  • Furthermore, Smad proteins, transcriptional effectors of TGF-β signaling, are co-expressed and physically interact in the basal ganglia with Dlx homeodomain transcription factors, which are critical regulators of the differentiation, migration and survival of telencephalic GABAergic neurons. (biomedcentral.com)
  • MSY3 (MSY4, YB-2, CSDA, dbpA, ZONAB) is a member of the cold shock domain (CSD) family of proteins also known as Y-box proteins, which are evolutionarily conserved proteins that function as transcription factors and regulators of RNA metabolism and protein synthesis. (biomedcentral.com)
Protein7
  • Transcription factor Sp1, also known as specificity protein 1* is a protein that in humans is encoded by the SP1 gene. (wikipedia.org)
  • The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. (wikipedia.org)
  • This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. (cancer-genetics.org)
  • The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. (cancer-genetics.org)
  • Here we show that components of both bone morphogenetic protein/growth differentiation factor and TGF-β/activin/Nodal branches of TGF-β superfamily signaling are expressed in the developing subpallium. (biomedcentral.com)
  • Four members of the mouse Dlx protein family (Dlx1, 2, 5 and 6), part of the Antennapedia class of non-Hox homeodomain transcription factors, are expressed in the embryonic subpallium (Panganiban and Rubenstein 2002 ). (biomedcentral.com)
  • We show that a member of the FK506-binding protein family, FKBP8, is an essential antagonist of SHH signaling in CNS development. (silverchair.com)
Promoters1
  • We also show that Dlx and Smad proteins localize to promoters/enhancers of a number of common telencephalic genes in vivo and that Smad proteins co-activate transcription with Dlx family members, except with certain mutated human DLX proteins identified in autistic individuals. (biomedcentral.com)
Proteins1
  • In that regard, recent studies in non-neural cells have suggested the existence of functional interactions between Dlx proteins and Smad transcription factors, which are critical mediators of transforming growth factor-β (TGF-β) superfamily signaling pathways (Chiba et al. (biomedcentral.com)
Tumor1
  • Withaferin A suppresses the expression of vascular endothelial growth factor in Ehrlich ascites tumor cells via Sp1 transcription" (PDF). (wikipedia.org)
Significantly1
  • Remarkably, at age 14 years, facial acne in girls was less influenced by genetic factors than in boys and was significantly influenced by common environmental factors [12]. (springer.com)
Growth1
  • Signaling mechanisms mediated by the Transforming Growth Factor-β (TGF-β) superfamily regulate a variety of developmental processes. (biomedcentral.com)
Development1
  • Together, these results suggest that TGF-β superfamily signaling plays a role in telencephalic GABAergic neuron development through functional interactions with Dlx transcription factors. (biomedcentral.com)
Data1
  • Data from family studies confirmed familial clustering [3-5]. (springer.com)
Common1
  • Once activated, R-Smads accumulate in the nucleus where they associate with Smad4, a common partner for all R-Smads, to form transcription complexes. (biomedcentral.com)
Cell1
Inhibit2
  • Plicamycin, an antineoplastic antibiotic produced by Streptomyces plicatus, and Withaferin A, a steroidal lactone from Withania somnifera plant are known to inhibit Sp1 transcription factor. (wikipedia.org)
  • At the molecular level, the organizer's inductive properties are mediated by factors that inhibit the BMP, Wnt, and Nodal signaling pathways. (biomedcentral.com)
Molecular weight1
  • HN - 2006(1981) BX - Actin-Capping Proteins MH - Actin Depolymerizing Factors UI - D051339 MN - D5.750.78.730.212 MN - D12.776.220.525.212 MS - A family of low MOLECULAR WEIGHT actin-binding proteins found throughout eukaryotes. (nih.gov)
Expression4
  • Withaferin A suppresses the expression of vascular endothelial growth factor in Ehrlich ascites tumor cells via Sp1 transcription" (PDF). (wikipedia.org)
  • Analysis of tissue weights, morphology, and gene expression was performed using standard histology, confocal imaging with three-dimensional analysis, real-time reverse transcription polymerase chain reaction (real-time RT-PCR), and microarrays. (nih.gov)
  • Meanwhile, Wnt inhibition acts later during gastrulation, and is essential for maintenance of organizer gene expression throughout gastrulation, a role which may depend on its ability to block the expression of a host of ventral, posterior, and lateral fate-specifying factors. (biomedcentral.com)
  • HN - 2006(1998) MH - Activating Transcription Factor 1 UI - D051697 MN - D12.776.260.108.61.500 MN - D12.776.930.127.61.500 MS - An activating transcription factor that regulates expression of a variety of genes including C-JUN GENES and TRANSFORMING GROWTH FACTOR BETA2. (nih.gov)