• PFOs, on the other hand, can only occur after birth when the foramen ovale fails to close. (heart.org)
  • There is some evidence that genetics may play a role in keeping a foramen ovale open, but generally PFOs are not thought to be inherited unless they are associated with other heart conditions. (c-r-y.org.uk)
  • Sukernik and Bennett-Guerrero ( 1 ) present a thorough and complete review of anatomy and physiology of patent foramen ovale (PFO), followed by an excellent discussion of echocardiographic techniques for diagnosing it. (lww.com)