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  • ovaries
  • Twenty-one day old mice were treated with eCG and hCG to induce follicle development and ovulation, respectively, and ovaries collected at different time points and fixed with paraformaldehyde. (calstatela.edu)
  • The maternal effect genes expressed in the mother's ovaries produce messenger RNAs that are placed in different regions of the egg. (nih.gov)
  • Schematics depicting development of individual follicles within the ovaries of model vertebrates. (nih.gov)
  • genes
  • The posterior group genes cappuccino , spire, mago nashi, staufen and oo18 , each of which are required for the localization of OSK mRNA to the posterior pole of the oocyte, are still required for OSK translation when Bruno-mediated translational repression is missing due to deleted BREs (Kim-Ha, 1995). (sdbonline.org)
  • Genes involved in RNA processing and ribosome biogenesis were destabilized with quiescence, while genes involved in the developmental process were stabilized with quiescence. (biomedcentral.com)
  • Among the genes surrounding the insertion, we found that Fibroblast Growth Factor 13 ( FGF13 ) mRNA levels were significantly reduced in affected individuals, and immunofluorescence staining revealed a striking decrease in FGF13 localization throughout the outer root sheath of affected hair follicles. (pnas.org)
  • Follicle-stimulating hormone (FSH) is a pituitary glycoprotein hormone that is encoded by separate alpha- and betasubunit genes. (koreascience.or.kr)
  • However, definitive proof that X-miRNA genes escape MSCI requires that nascent precursors of miRNAs, so-called pri-miRNAs, are generated during pachynema, and ideally, that these can be visualised as nascent transcripts originating from the otherwise inactive X chromosome, e.g. by techniques such as RNA FISH. (prolekare.cz)
  • Beyond relevant coding genes, microRNA (miRNA) and long non coding RNA (lncRNA) play an indispensable role in hair follicle (HF) development and skin homeostasis. (biomedcentral.com)
  • microRNA
  • Analysis of miR-29 target decay rates suggests that microRNA-induced changes in RNA stability are important contributors to the quiescence gene expression program in fibroblasts. (biomedcentral.com)
  • Cytoplasm
  • The pre-miRNA is exported to the cytoplasm via Exportin-5, where it is cleaved by the cytoplasmic RNase III enzyme Dicer-1 (Dcr-1) and its double-strand RNA-binding domain partner Loquacious (Loqs). (sdbonline.org)
  • During previtellogenesis high levels of Sxl RNA accumulate in the cytoplasm of nurse cells while lower levels are detected in the somatically derived follicle cells tht surround each egg chamber. (sdbonline.org)
  • embryos
  • Moreover, when the RNA of the anterior of insect eggs was destroyed (by either ultraviolet light or RNase), the resulting embryos lacked a head and thorax. (nih.gov)
  • endogenous
  • microRNAs (miRNAs) are a class of endogenous regulatory RNAs that play a key role in myriad biological processes. (sdbonline.org)
  • regulation
  • Appropriate expression of StAR gene represents an indispensable component of steroidogenesis and its regulation has been found to be species specific. (koreascience.or.kr)
  • repression
  • Non-coding RNAs have a prominent role in gene silencing, e.g. in X chromosome inactivation [ 28 ], and repression of transposable elements and centromeric repeats [ 29 ], and it is therefore possible that X-linked miRNAs contribute to the process of MSCI itself. (prolekare.cz)
  • ribosome
  • Identified in a HCV IRES-mediated translation complex, that enhances translation at the Hepatitis C virus (HCV) RNA-replicon via the internal ribosome entry site (IRES), but does not affect 5'cap-dependent translation. (abcam.com)
  • signaling pathway
  • A subset of these putative antimicrobial effectors is regulated by the p38 MAPK signal transduction cascade, demonstrating a direct link between a specific immune signaling pathway and the induced response to pathogen infection ( 15 ). (pnas.org)
  • mRNP
  • Previous studies suggested that Zfrp8 functions in the formation of mRNP (mRNA ribonucleoprotein) complexes and also controls RNA of select Transposable Elements (TEs). (sdbonline.org)
  • cells
  • Tightly associated with it, Grk will be secreted to the adjacent follicle cells (gray grid), which will acquire a dorsal fate and later synthesize the dorsal appendages of the chorion (not shown). (genetics.org)
  • This protocol is used to determine the spatial and phenotypic characteristics of antigen-specific CD8 T cells relative to other cell type and structures in tissues. (jove.com)
  • In the case of T cell-dependent antibody responses, antigen-engaged B cells receive T cell help in the region of the T zone-bordering follicles. (rupress.org)
  • While the plasma cell response is ongoing, small numbers of B cells colonize B cell follicles and differentiate into germinal center cells. (rupress.org)
  • As they mature to an IgD + stage, B cells upregulate CXCR5 and acquire responsiveness to CXCL13 (BLC), a chemokine made in follicles of secondary lymphoid organs ( 22 ). (rupress.org)
  • A little later, when the follicle cells start to invade centripetally and surround the newly formed 16-cell cluster in region 2 of the germarium, a second change in localization occurs. (sdbonline.org)
  • In follicle cells, Sxl is present in nuclei. (sdbonline.org)
  • small
  • However, the activity of X-derived non-coding RNAs, and especially small RNAs, during pachynema is less well understood. (prolekare.cz)
  • activity
  • Characteristic stage-specific changes of bioelectric activity in specialized cell types are correlated with various developmental processes. (biomedcentral.com)
  • The RNA-binding activity to ARS is stimulated by PABPC1. (abcam.com)
  • secondary
  • Blots were incubated with AMPK immunopurified goat anti-human AMPK ±1- and ±2-specific antibodies, and detected with rabbit anti-goat secondary antibodies. (calstatela.edu)
  • patterns
  • Previously characterized innate immune responses in plants and animals are triggered by detection of pathogens using specific receptors, which typically use a leucine-rich repeat (LRR) domain to bind molecular patterns associated with infection. (pnas.org)