Medial temporal lobesEpilepsyHippocampusFunctionalInferiorOccipital lobeSuperior temporal sulcusStructuresAtrophyBilateralFronto-temporalActivationsSomatosensorySeizureHippocampal sclerosisPosteriorAnterior temporalCortexPatientsNeural correlatesFrontal languageSpatialLeftCorrelatesSubjectsStudyBrainContributionsRevealsArcuate fasciculusFacilitatesDetectionVerbalRepresentationsCognitiveRearDataCorticesActivityOrganizationFoundRegionsAreasSignificant
Medial temporal lobes1
- FMRI showed heightened activity mainly in a front portion of the medial temporal lobes when subjects correctly identified a new word. (diagnosticimaging.com)
Epilepsy12
- We aimed to investigate the influence of CBZ on memory induced activation of the mesial temporal lobes in patients with symptomatic temporal lobe epilepsy (TLE). (biomedcentral.com)
- FMRI appears to be suitable to study the effects of chronic drug treatment in patients with epilepsy. (biomedcentral.com)
- Using a recently described memory fMRI paradigm for single case studies we aimed to determine possible interactions between CBZ serum levels and fMRI response in mesial temporal lobe structures of patients with chronic symptomatic temporal lobe epilepsy (TLE) [ 9 ]. (biomedcentral.com)
- Temporal lobe epilepsy is the most common epilepsy syndrome in adults. (medscape.com)
- Patients with newly diagnosed temporal lobe epilepsy should have a high-resolution MRI scan with at least a 1.5-Tesla MRI. (medscape.com)
- Chernov et al found that single-voxel proton magnetic resonance spectroscopy (MRS)-detected reduction of N- acetylaspartate content and unilateral presence of lactate in the mesial temporal lobe structures may serve as diagnostic clues for lateralization of the epileptogenic zone in mesial temporal lobe epilepsy. (medscape.com)
- The investigators conducted a retrospective study to evaluate the role of single-voxel proton MRS in preoperative investigation of patients with mesial temporal lobe epilepsy. (medscape.com)
- DTI detected extensive changes in mesial temporal lobe epilepsy with hippocampus sclerosis. (medscape.com)
- Neural response to stress and perceived stress differ in patients with left temporal lobe epilepsy. (uc.edu)
- Physiologic and cortical response to acute psychosocial stress in left temporal lobe epilepsy - a pilot cross-sectional fMRI study. (uc.edu)
- Contributions of fMRI towards our understanding of the response to psychosocial stress in epilepsy and psychogenic nonepileptic seizures. (um.es)
- Ictal spitting in left temporal lobe epilepsy and fMRI speech lateralization. (ac.rs)
Hippocampus6
- The structures of the mesial temporal lobe include the hippocampus, amygdala, and parahippocampal gyrus. (medscape.com)
- Provenzale et al confirmed that MRI findings of a markedly hyperintense hippocampus in children with febrile status epilepticus was highly associated with subsequent mesial temporal sclerosis. (medscape.com)
- The brain structure imaging analysis of patients with AD and normal people (normal control, NC) has found that the gray matter volume of AD patients was significantly lower than that of normal people, and the gray matter in the hippocampus, temporal poles, and temporal islands also has significant shrinkage [ 1 ]. (hindawi.com)
- The main intergroup difference was found in the left hippocampus and surrounding medial temporal lobe (MTL) regions for the patients with MCI compared with healthy subjects during successful encoding. (bmj.com)
- We now know that Tolman's cognitive maps are generated by the hippocampus and surrounding temporal lobe structures, which are crucial for the spatial memory which is required for navigation. (scienceblogs.com)
- The fMRI scans further revealed a crucial difference in activity in the portion of the temporal lobe - the hippocampus - that is known to be central for episodic memories. (psypost.org)
Functional15
- a drug widely used in neurology and psychiatry) influences the blood oxygenation level dependent (BOLD) contrast changes induced by neuronal activation and measured by functional MRI (fMRI). (biomedcentral.com)
- Functional magnetic resonance imaging of the brain (fMRI) is no longer exclusively used in normal control subjects and highly selected patients, but increasingly applied to large numbers of chronically ill patients in clinical neurology and psychiatry [ 1 ]. (biomedcentral.com)
- In the macaque, electrophysiological and functional magnetic resonance imaging (fMRI) studies have localized candidate areas that could encode facial movements. (jneurosci.org)
- Investigations of memory in rats and nonhuman primates have demonstrated functional specialization within the medial temporal lobe (MTL), a set of heavily interconnected structures including the hippocampal formation and underlying entorhinal, perirhinal, and parahippocampal cortices. (jneurosci.org)
- First, the data on structural magnetic resonance imaging (sMRI) and functional magnetic resonance imaging (fMRI) are preprocessed to remove the influence resulting from the differences in image size and shape of different individuals, head movement, noise, and so on. (hindawi.com)
- At present, structural MRI (sMRI) and functional MRI (fMRI) are widely used in the diagnosis of Alzheimer's disease (AD). (hindawi.com)
- Many neuroimaging studies have demonstrated the potential of functional network connectivity patterns estimated from resting functional magnetic resonance imaging (fMRI) to discriminate groups and predict information about individual subjects. (biorxiv.org)
- We used functional MRI (fMRI) to compare brain activity during memory encoding in 29 healthy elderly subjects (mean age 67.7 (SD 5.4) years) and 21 patients with MCI (mean age 69.7 (SD 7.0) years). (bmj.com)
- We then employed a measure of global resting-state functional brain connectivity and follow-up seed-to-voxel analysis to the fMRI data we acquired. (researchgate.net)
- Therefore, this thesis investigated the schema effect on memory in humans using behavioural memory tasks along with functional Magnetic Resonance Imaging (fMRI) techniques, that allow to examine the neural mechanisms underlying the schema effect. (ru.nl)
- Here, she took part in a series of detailed investigations, including functional magnetic resonance imaging (fMRI), neuropsychological evaluations designed to test general intelligence, memory and visuospatial abilities and various assessments of her navigational skills. (scienceblogs.com)
- One week later, they either underwent memory testing where they had to recall the events and provide details about what had happened, in which order, and what they felt, or they had to try to remember the events while they underwent brain imaging with functional magnetic resonance imaging (fMRI). (psypost.org)
- Structural and functional imaging approaches in attention deficit/hyperactivity disorder : does the temporal lobe play a key role? (unibas.ch)
- We applied different structural imaging techniques such as voxel-based morphometry (VBM), diffusion tensor imaging (DTI), and magnetization transfer imaging (MTI) to study anatomical differences between boys with ADHD and healthy controls, as well as functional magnetic resonance imaging (fMRI) together with independent component analysis (ICA) to detect functional alterations. (unibas.ch)
- One example is so-called functional MRI (fMRI) in which the MRI scanner measures the parts of the brain that are activated by conscious and unconscious impressions or by actions that are carried out such as moving a part of the body, talking, listening, or looking at something. (lu.se)
Inferior5
- Diffusive tensor imaging tractography is used to describe the asymmetry of an arcuate fasciculus, a pathway that connects the temporal and inferior frontal language cortices (Glasser & Rilling, 1991) . (scirp.org)
- He treated three patients who had acquired face blindness through an injury to the inferior temporal cortex. (theartnewspaper.com)
- Picking up on the work of Bodamer on the one hand and Hubel and Wiesel on the other, Charles Gross began in 1969 to examine single cells in the inferior temporal cortex of monkeys. (theartnewspaper.com)
- Then, the inferior lateral area of the temporal lobe changes obviously, and finally, the frontal lobe begins to shrink [ 2 ]. (hindawi.com)
- Group differences in the inferior temporal lobe were detected. (unibas.ch)
Occipital lobe2
- Of the four lobes of UD's right hemisphere, the entire occipital lobe, which includes the vision processing center of the brain, and most of the temporal lobe, which receives both visual and auditory cues, were removed. (neurosciencenews.com)
- Agnosia is caused by damage to the parietal, temporal, or occipital lobe of the brain. (msdmanuals.com)
Superior temporal sulcus3
- A role for the right superior temporal sulcus in categorical perception of musical chords. (crossref.org)
- The macaque provides a model visual system for studying neural coding of expression movements, as its superior temporal sulcus (STS) possesses brain areas selective for faces and areas sensitive to visual motion. (jneurosci.org)
- We investigated the neural computations which might support this feat, using the macaque superior temporal sulcus (STS) as a model system. (jneurosci.org)
Structures4
- In most patients, the epileptogenic focus involves the structures of the mesial temporal lobe (illustrated in the diagrams below). (medscape.com)
- Diagram of the hippocampal anatomy and adjacent structures in the mesial temporal lobe. (medscape.com)
- In addition, the presence of significant bilateral metabolic alterations in the mesial temporal lobe structures was associated with worse postoperative seizure control. (medscape.com)
- Much neuropsychological and neuroimaging research has been focused on the contributions of different medial temporal lobe (MTL) structures to recognition memory. (uwo.ca)
Atrophy3
- Marked neuronal loss and cortical atrophy, especially in right ventral and dorsal frontal and anterior temporal regions. (medscape.com)
- Van de Pol et al found that medial temporal lobe atrophy seems to be a more important predictor of cognition than small-vessel disease in MCI. (medscape.com)
- Lacunes were associated with performance on the Digit Symbol Substitution Test, especially in subjects with milder median temporal lobe atrophy (MTA). (medscape.com)
Bilateral2
- PET imaging revealed decreased regional cerebral blood flow (rCBF) in areas including the left amygdala, dorsal anterior cingulate, posterior cingulate, medial temporal lobe (MTL), and bilateral insula (Gamma et al, 2000). (researchgate.net)
- Axial, T2-weighted magnetic resonance imaging (MRI) scan reveals atrophic changes within bilateral temporal lobes with prominence of the sylvian fissures. (medscape.com)
Fronto-temporal2
- High-level language processing is supported by a left-lateralized fronto-temporal brain network. (biorxiv.org)
- In the adult human brain, language processing recruits a fronto-temporal network (e.g. (biorxiv.org)
Activations1
- Recent fMRI studies have suggested increased medial temporal lobe (MTL) activations in MCI subjects versus controls, during the performance of memory tasks [ 16 , 17 ]. (hindawi.com)
Somatosensory1
- and decreases in the motor and somatosensory cortex, temporal lobe including left amygdala, cingulate cortex, insula and thalamus. (researchgate.net)
Seizure1
- All patients fulfilled the following criteria: unilateral seizure onset of temporal lobe origin shown by continuous interictal and ictal video/EEG monitoring with scalp and sphenoidal electrodes, and unilateral lesions within the temporal lobes demonstrated by high resolution routine MRI. (biomedcentral.com)
Hippocampal sclerosis2
- Ten patients had hippocampal sclerosis, three vascular lesions, two tumors, and six miscellaneous or cryptogenic temporal lobe lesions. (biomedcentral.com)
- Neuroimaging is vital for the identification of organic or structural anomalies, which may precipitate temporal lobe seizures, such as vascular malformations, tumors, and hippocampal sclerosis. (medscape.com)
Posterior2
- It is supposed that the arcuate fasciculus consists of two segments with different functions: one terminates in the posterior superior temporal gyrus (STG), and another terminates in the middle temporal gyrus (MTG). (scirp.org)
- Negative components showed activation in anterior and posterior cingulate cortex/precuneus and temporal regions, and were interpreted as forming part of the default mode network. (unibas.ch)
Anterior temporal2
- When seizures persist, anterior temporal lobectomy is the treatment of choice. (medscape.com)
- Researchers discovered that neural activity in the left ventral temporoparietal junction (vTPJ) and the lateral anterior temporal lobe (lATL) during sentence processing is tied to social-semantic working memory. (neurosciencenews.com)
Cortex6
- Phonetic perception and the temporal cortex. (crossref.org)
- Given that frontal cortex in general exhibits protracted development, frontal language areas presumably emerge later and/or mature more slowly than temporal language areas. (biorxiv.org)
- However, another network implicated in high-level cognition- the domain-general multiple demand, MD, network-is robustly present in both right and left frontal lobes, suggesting that EG's left frontal cortex is capable of supporting non-linguistic cognitive functions. (biorxiv.org)
- A temporal record of the past with a spectrum of time constants in the monkey entorhinal cortex. (upenn.edu)
- Findings point towards two different competing mechanisms in the brain that are mediated by two brain regions, the medial temporal lobe (MTL) and the medial prefrontal cortex (mPFC) and are suggested to store memories in different ways as a function of their congruency with a pre-existing schema. (ru.nl)
- However, we could see activity in the frontal lobe cortex, so they were really making an effort to remember. (psypost.org)
Patients4
- Twenty-one individual patients with refractory symptomatic TLE with different CBZ serum levels and 20 healthy controls were studied using BOLD fMRI. (biomedcentral.com)
- In TLE patients, carbamazepine reduces the fMRI-detectable changes within the mesial temporal lobes as induced by effortful memory retrieval. (biomedcentral.com)
- There is no information whether the intravenous concentration of CBZ interferes with task-related contrast changes of fMRI in patients treated chronically with CBZ. (biomedcentral.com)
- Nonetheless, fMRI findings in MCI are discrepant, as MTL hypoactivation similar to that seen in AD patients [ 18 ] has also been reported [ 19 ]. (hindawi.com)
Neural correlates2
- The quantitative electroencephalography (QEEG) is an investigation tool possessing a proper temporal resolution in the study of neural correlates of cognitive tasks at cortical level. (researchgate.net)
- Here, I report results from three fMRI studies that examined the neural correlates of item recognition with a specific focus on the relationship between such signals and category-specific effects in the MTL. (uwo.ca)
Frontal language2
- But are temporal areas necessary for the development of the language areas in the frontal lobe, or do frontal language areas instead emerge independently? (biorxiv.org)
- However, her RH frontal language areas have no corresponding LH homotopic areas: no reliable response to language is detected on the lateral surface of EG's left frontal lobe. (biorxiv.org)
Spatial4
- Mesial temporal lobe (MTL) activation was induced by a task that is based on the retrieval of individually familiar visuo-spatial knowledge. (biomedcentral.com)
- Up until recently, researchers believed that involuntary memories were a result of traumatic incidents that the individual experienced at a specific time and place, while losing all the temporal and spatial features of the event during an involuntary recollection episode. (wikipedia.org)
- Although larger response magnitudes were reported for scenes presented contralaterally, fMRI adaptation was found not to depend on visual field position, indicating perhaps, the presence of receptive fields that span the vertical meridian ( MacEvoy and Epstein, 2007 ) and suggesting RSC plays a more prominent role in spatial memory rather than scene perception per se ( MacEvoy and Epstein, 2007 ). (frontiersin.org)
- To do this, we develop a deep Siamese framework comprising three-dimensional convolution neural networks for contrastive learning based on individual-level spatial maps estimated via a fully automated fMRI independent component analysis approach. (biorxiv.org)
Left3
- Increased cortical surface area of the left planum temporale facilitates the discrimination of temporal speech information in musicians. (crossref.org)
- We shed light on this question through a case study of an individual (EG) born without a left temporal lobe. (biorxiv.org)
- In most individuals, this network is dominant in the left hemisphere (LH), as evidenced by both i) more robust LH activity in response to language processing as measured with fMRI and other brain imaging techniques (e.g. (biorxiv.org)
Correlates1
- Neurofunctional and behavioral correlates of phonetic and temporal categorization in musically trained and untrained subjects. (crossref.org)
Subjects2
- However, fMRI displayed activity in the lobes' rear portion when subjects viewed an old word, even if they failed to remember it. (diagnosticimaging.com)
- Subjects remembered a list of words while fMRI data were acquired. (bmj.com)
Study2
- Gender effects in alcohol dependence: an fMRI pilot study examining affective processing. (uc.edu)
- Using fMRI experiments, the study demonstrated that these regions respond to sentences with social meaning and maintain activity even after the linguistic stimulus is gone. (neurosciencenews.com)
Brain6
- In these settings, fMRI is used to explore neuronal (dys-)function in or close to brain regions implicated in the assumed disease processes. (biomedcentral.com)
- In addition, the PCANet network is applied to the brain function connection analysis, and the features on fMRI data are obtained. (hindawi.com)
- fMRI is used to measure the changes in hemodynamics caused by neuronal activity which can show the location and extent of brain activation and can detect dynamic changes in the brain over a period of time. (hindawi.com)
- Deep learning algorithms are also widely used in fMRI-assisted diagnosis of brain diseases. (hindawi.com)
- Gender differences in brain areas involved in silent counting by means of fMRI. (ac.rs)
- Axial, T2-weighted magnetic resonance imaging (MRI) scan of the brain reveals atrophic changes in the temporal lobes. (medscape.com)
Contributions1
Reveals1
- Comparative fMRI in dogs and humans reveals functionally analogous body- and animacy responsive areas in the occipito-temporal lobe of both species and divergent neural representations of faces and conspecific bodies in dog olfactory regions. (nature.com)
Arcuate fasciculus1
- The affected networks were principally in the ipsilateral temporal lobe and the limbic system, but also in the arcuate fasciculus. (medscape.com)
Facilitates1
- This annotated, multilingual fMRI dataset facilitates future re-analysis that addresses cross-linguistic commonalities and differences in the neural substrate of language processing on multiple perceptual and linguistic levels. (nature.com)
Detection1
- Detection of differential speech-specific processes in the temporal lobe using fMRI and a dynamic “sound morphing” technique. (crossref.org)
Verbal1
- Parsing for noun plurals appears to be a time-costly process, which we attribute to the ambiguity of -en,a suffix that is predominantly used as a verbal ending. (mpi.nl)
Representations1
Cognitive1
- Here we present the Le Petit Prince fMRI Corpus (LPPC-fMRI), a multilingual resource for research in the cognitive neuroscience of speech and language during naturalistic listening (OpenNeuro: ds003643). (nature.com)
Rear1
- In addition, we see areas beyond the eye in something called Broca's area in the rear/lower frontal lobe that is related to the processing of grammar. (lu.se)
Data4
- The resulting timeseries data are shown to be of high quality with good temporal signal-to-noise ratio and high inter-subject correlation. (nature.com)
- Here we present Le Petit Prince fMRI Corpus (LPPC-fMRI) 5 , a multilingual fMRI dataset where English, Chinese and French speakers listened to the same audiobook Le Petit Prince (The Little Prince) in their native language (see Fig. 1 for a Schematic overview of the LPPC-fMRI data collection, preprocessing, technical validation and annotation procedures). (nature.com)
- Schematic overview of the LPPC-fMRI data collection procedures, preprocessing, technical validation and annotation. (nature.com)
- Our data show that endogenous opioidergic activation in the medial temporal lobe is centrally involved in sexual arousal, and this circuit may be implicated in orgasmic disorders. (snmjournals.org)
Cortices2
- Or only a subset of long-range projection cells in frontal lobes that project to the sensory cortices in the back? (scholarpedia.org)
- These are 3-repeat tau-immunopositive bodies predominantly located in granular neurons in the hippocampal dentate gyrus, hippocampal CA1 pyramidal neurons, and layer II of frontal and temporal cortices. (medscape.com)
Activity1
- Activity is seen in areas of the upper temporal lobe (just above the ear) which, somewhat simplified, take care of sound signals in general, and which also have areas that respond specifically to language sounds. (lu.se)
Organization1
- Current theories of medial temporal lobe (MTL) memory organization are in conflict regarding two major issues. (jneurosci.org)
Found1
- In the report, by Zijlmans et al, 3T was found to reveal more dysplasias, while 1.5T revealed more tissue loss and mesial temporal sclerosis. (medscape.com)
Regions1
- Parallel independent component analysis (parallel-ICA) was used to examine the relationship between language-related regions extracted from resting-state fMRI and 16 single nucleotide polymorphisms (SNPs) spanning 5 RD-related genes. (nih.gov)
Areas1
- We also show that some of the motion sensitivity elicited by facial stimuli was not specific to faces but could also be elicited by moving dots, particularly in fundus of the superior temporal and middle superior temporal polysensory/lower superior temporal areas, confirming their already well established low-level motion sensitivity. (jneurosci.org)
Significant2
- The extent of significant MTL fMRI activation was measured and correlated with the CBZ serum level. (biomedcentral.com)
- Parallel-ICA identified four significant fMRI-SNP relationships. (nih.gov)