• Flutamide, sold under the brand name Eulexin among others, is a nonsteroidal antiandrogen (NSAA) which is used primarily to treat prostate cancer. (wikipedia.org)
  • Eulexin (flutamide) Capsules is an antiandrogen used to treat prostate cancer . (rxlist.com)
  • Our Eulexin (flutamide) Capsules Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. (rxlist.com)
  • EULEXIN Capsules contain flutamide, an acetanilid, nonsteroidal, orally active anti- androgen having the chemical name, 2-methyl-N-[4-nitro-3 (trifluoromethyl) phenyl] propanamide. (rxlist.com)
  • The inactive ingredients for EULEXIN (flutamide) Capsules include: corn starch, lactose, magnesium stearate, povidone, and sodium lauryl sulfate. (rxlist.com)
  • EULEXIN (flutamide) Capsules are indicated for use in combination with LHRH agonists for the management of locally confined Stage B 2 -C and Stage D 2 metastatic carcinoma of the prostate . (rxlist.com)
  • Treatment with EULEXIN (flutamide) Capsules and the LHRH agonist should start 8 weeks prior to initiating radiation therapy and continue during radiation therapy. (rxlist.com)
  • To achieve benefit from treatment, EULEXIN (flutamide) Capsules should be initiated with the LHRH agonist and continued until progression. (rxlist.com)
  • Treatment with EULEXIN (flutamide) Capsules and the LHRH agonist did not add substantially to the toxicity of radiation treatment alone. (rxlist.com)
  • The following adverse experiences were reported during a multicenter clinical trial comparing EULEXIN (flutamide) Capsules + LHRH-A +radiation versus radiation alone. (rxlist.com)
  • We conducted a chemical library screen to identify nontoxic AhR ligands with anti-cancer effects and discovered flutamide (Eulexin) as a putative AhR ligand. (oregonstate.edu)
  • A dosage of 750 mg/day flutamide (250 mg/three times a day) is roughly equivalent in terms of effectiveness to 50 mg/day bicalutamide when used as the antiandrogen component in combined androgen blockade in the treatment of advanced prostate cancer. (wikipedia.org)
  • Flutamide, a nonsteroidal antiandrogen drug widely used in the treatment of prostate cancer, has been associated with rare incidences of hepatotoxicity in patients. (unboundmedicine.com)
  • Classification Flutamide is an antiandrogen. (gpatindia.com)
  • The first and only case report of AKI associated with ADT (the oral antiandrogen flutamide) was published in 2002 by Turkish clinicians ( Med Oncol . (medscape.com)
  • Flutamide has been found to be similarly effective in the treatment of prostate cancer to bicalutamide, although indications of inferior efficacy, including greater compensatory increases in testosterone levels and greater reductions in PSA levels with bicalutamide, were observed. (wikipedia.org)
  • Flutamide is an androgen receptor (AR) antagonist approved by the United States Food and Drug Administration for the treatment of prostate cancer. (oregonstate.edu)
  • The U.S. FDA-approved Flutamide to treat people with prostate cancer conditions on 27th January 1989. (mrmed.in)
  • Flutamide is used to treat advanced prostate cancer in men. (mrmed.in)
  • Buy Cytomid 250 mg (Flutamide), Flutamide is used either alone or in combination to treat prostate cancer. (alldaygeneric.com)
  • Flutamide is also used to treat prostate cancer which has spread to other parts of the body (advanced cancer). (alldaygeneric.com)
  • The compound set contained 67 nonsteroidal analogues of flutamide, nilutamide, and bicalutamide whose binding mode to AR was unknown. (nih.gov)
  • We investigated the AhR-dependent mechanism of action of flutamide in human hepatocellular carcinoma cells and identified that transforming growth factor-β1 (TGF-β1) is induced by flutamide in an AhR-dependent manner. (oregonstate.edu)
  • Flutamide is in a class of medications called nonsteroidal antiandrogens. (medlineplus.gov)
  • Flutamide belongs to a group of medications known as nonsteroidal antiandrogens . (rxhealthmed.ca)
  • Nonsteroidal antiandrogens such as flutamide block the effect of the male hormone testosterone in the body. (rxhealthmed.ca)
  • Flutamide belongs to a group of medicines called non-st***dal antiandrogens. (alldaygeneric.com)
  • Flutamide was initially used at the beginning of GnRH agonist therapy to block this surge, and it and other NSAAs continue in this use. (wikipedia.org)
  • You may not be able to take flutamide, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above. (us.org)
  • Two other medications , called spironolactone and flutamide, may also treat acne and hirsutism caused by PCOS. (medicalnewstoday.com)
  • Continue to take flutamide along with the LHRH agonist treatment even if you feel well. (medlineplus.gov)
  • Flutamide tablets may be given in combination with LHRH agonists. (mrmed.in)
  • Anti-androgen flutamide suppresses hepatocellular carcinoma cell proliferation via the aryl hydrocarbon receptor mediated induction of transforming growth factor-β1. (oregonstate.edu)
  • ZOLADEX is indicated for use in combination with flutamide for the management of locally confined Stage T2b-T4 (Stage B2-C) carcinoma of the prostate. (nih.gov)
  • Numerous cases of liver failure and death have been reported, which has limited the use of flutamide. (wikipedia.org)
  • Flutamide may cause liver damage that can be serious or life-threatening. (medlineplus.gov)
  • Your doctor will order certain blood tests to check how well your liver is working before you begin taking flutamide, every month for the first 4 months of your treatment, and periodically for as long as your treatment continues. (medlineplus.gov)
  • There have been postmarketing reports of hospitalization and rarely death due to liver failure in patients taking flutamide. (rxlist.com)
  • If at any time a patient has jaundice, or their ALT rises above 2 times the upper limit of normal, flutamide should be immediately discontinued with close follow-up of liver function tests until resolution. (rxlist.com)
  • NADPH- and GSH-supplemented human liver microsomal incubations of flutamide gave rise to a novel GSH conjugate where GSH moiety was conjugated to the flutamide molecule via the amide nitrogen, resulting in a sulfenamide. (unboundmedicine.com)
  • Interestingly, the same adduct was formed when flutamide was incubated with human liver microsomes in the presence of GSSG and NADPH. (unboundmedicine.com)
  • Flutamide should be used cautiously in patients with liver problems. (mrmed.in)
  • Serious side effects while taking Flutamide are liver problems (hepatitis), stomach pain, dark urine, allergic reaction swelling in the leg and other parts. (mrmed.in)
  • Your doctor will need to monitor your liver function with blood tests before starting treatment with flutamide, every month for the first 4 months of treatment, and periodically thereafter. (us.org)
  • In rare cases, flutamide has caused severe liver damage resulting in death or hospitalization. (us.org)
  • Flutamide is an orally administered drug. (mrmed.in)
  • The relative potency of C47 to the reference compound flutamide was over 5.2, whereas the derivatives were less potent. (chemaxon.com)
  • Approximately half of the reported cases occurred within the initial 3 months of treatment with flutamide. (rxlist.com)
  • Serum transaminase levels should be measured prior to starting treatment with flutamide. (rxlist.com)
  • Short-term treatment with flutamide applied to adult rats exerts its primary effect on the basal ES, coexisting junctional complexes and their constituent proteins Cx43 and ZO-1, without any apparent morphological alterations in the seminiferous epithelium. (biomedcentral.com)
  • Drink plenty of liquids while you are on flutamide treatment. (alldaygeneric.com)
  • Like all medicines, Flutamide 250 mg Tablets can cause unwanted side effects, particularly when you first start taking them, although not everybody gets them. (siddhaglobal.com)
  • Flutamide Tablet inhibits the uptake of a hormone called androgen and prevents this hormone from binding to the tissues. (mrmed.in)
  • If you have overdosed on Flutamide tablets or someone accidentally takes your tablet, contact the hospital or a doctor immediately for medical advice. (mrmed.in)
  • Flutamide is available only in tablet form. (mrmed.in)
  • Store Flutamide in the original package at room temperature (20°C to 25°C). Keep the tablets away from the reach of children and pets. (mrmed.in)
  • Store flutamide at room temperature away from moisture and heat. (us.org)
  • tell your doctor and pharmacist if you are allergic to flutamide or any other medications. (medlineplus.gov)
  • If taken by pregnant women, flutamide can harm the fetus. (medlineplus.gov)
  • As shown by examination of semi-thin and ultrathin sections, cell surface occupied by the basal ES connecting neighboring Sertoli cells and the number of gap and tight junctions coexisting with the basal ES were apparently reduced in flutamide-treated rats. (biomedcentral.com)
  • Although it is rare, some men taking flutamide have developed breast cancer. (medlineplus.gov)
  • We found that flutamide inhibited the growth of several cancer cell lines independent of AR status, and that suppression of AhR expression reversed the anti-proliferative effects of flutamide. (oregonstate.edu)
  • Siddha Global is Supplier,Exporter ,Wholesaler for Flutamide Tablets 250 mg in India. (siddhaglobal.com)
  • Talk to your doctor about the risks of taking flutamide. (medlineplus.gov)
  • ask your doctor about the safe use of alcoholic beverages while you are taking flutamide. (medlineplus.gov)
  • Do not stop taking Flutamide without talking to your doctor. (mrmed.in)
  • Flutamide is not recommended for women and children. (mrmed.in)
  • Can we use Flutamide in children and women? (mrmed.in)
  • No, Flutamide is not intended for women. (mrmed.in)
  • Flutamide is not indicated for use by women. (us.org)
  • In contrast, estrogens (estradiol, bisphenol-A, and 4-tert-octylphenol), pure anti-estrogen ICI 182,780 (ICI), and anti-androgens (4-OH-flutamide or the vinclozolin metabolite M-2) had no effect on P production even at 1000 nM. (cdc.gov)
  • flutamide reversed this effect. (bvsalud.org)
  • Avoid dairy products such as milk, cheese, and yogurt to prevent diarrhea and do not use laxatives while taking flutamide. (alldaygeneric.com)
  • Flutamide is usually taken three times a day (every 8 hours). (us.org)