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  • molecules
  • IRDye maleimides provide the functionality for labeling molecules that contain free sulfhydryl (-SH) groups with IRDye infrared dyes. (licor.com)
  • In a new study, published online in the journal Angewandte Chemie International Edition, a team of chemists and biologists at the Institute of Transformative Bio-Molecules (ITbM), Nagoya University has developed a new fluorescent dye, "C-Naphox" with enhanced photostability to enable continuous live cell imaging by STED microscopy, which opens doors to observe real-time biological events for extended time periods with high resolution. (innovations-report.com)
  • excitation
  • Detergent micelles will also bind the dye and increase background noise dramatically - this effect is lessened by switching to the dye ANS but that requires UV excitation. (wikipedia.org)
  • particles
  • Depending on the chemical structure of the dye, the particles are filtered out of the blood either via the kidney tissue or via liver cells," said professor Dr. Michael Bauer of the Jena University Hospital Center for Sepsis Control and Care. (photonics.com)
  • blue
  • Dansyl chloride or 5-(DimethylAmino)Naphthalene-1-SulfonYL chloride is a reagent that reacts with primary amino groups in both aliphatic and aromatic amines to produce stable blue- or blue-green-fluorescent sulfonamide adducts. (wikipedia.org)
  • voltage
  • Leech neurons stained with voltage-sensitive dye. (ucsd.edu)
  • One of the tradeoffs with using voltage-sensing dyes in the past is that when they were reasonably sensitive to voltage changes, they were slow compared to the actual physiological events," said Miller. (ucsd.edu)
  • Applications
  • These unique dyes are used in a variety of NIR imaging applications including Western blotting , plate-based assays , protein arrays, tissue section imaging, probe development , and small animal imaging . (licor.com)
  • protein
  • However, current monitoring methods fall short, said the study's first author Evan W. Miller, a post-doctoral researcher in the lab of Roger Tsien, PhD, Howard Hughes Medical Institute investigator, UC San Diego professor of pharmacology, chemistry and biochemistry and 2008 Nobel Prize co-winner in chemistry for his work on green fluorescent protein. (ucsd.edu)
  • Some of the values are used to estimate the extent of success in attempts to conjugate the dye to a protein. (wikipedia.org)
  • experimental
  • A novel technique that uses DNA-binding fluorescent dyes to evaluate the cytotoxicity of an experimental compound in real-time during screening, saving time and resources, is described in ASSAY and Drug Development Technologies , a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. (eurekalert.org)
  • fluid
  • Fluorescent aerogels were prepared by replacing water in the gels with methanol and then exposing them to supercritical fluid drying conditions. (osti.gov)
  • cells
  • The new method employs dyes that penetrate only the membrane of neurons, either in in vitro cells cultured with the dye or, for this study, taken up by neurons in a living leech model. (ucsd.edu)
  • But the dyes also play another key function: Because they mimic a cellular transporter of liver epithelial cells, the liver absorbs them readily. (photonics.com)
  • Hydrolyzes to green-fluorescent calcein on contact with intracellular esterases in live cells. (abcam.com)
  • Lucius Chiaraviglio and James Kirby, Beth Israel Deaconess Medical Center, evaluated 19 fluorescent DNA-binding dyes and identified four dyes that were not harmful to cells and could not cross the cell membrane if a cell was viable. (eurekalert.org)
  • chemistry
  • Swager, who is head of the chemistry department, and colleagues developed the new dye, called NIAD-4, through a targeted design process based on a set of specific requirements, including the ability to enter the brain rapidly upon injection, bind to amyloid plaques, absorb and fluoresce radiation in the right spectral range, and provide sharp contrast between the plaques and the surrounding tissue. (medgadget.com)
  • In a recent paper that appeared in the Journal of the American Chemical Society , Professor Victor Nemykin ( Chemistry and Biochemistry , University of Minnesota Duluth ) and his collaborators at the University of Akron (Akron, Ohio) discuss a new fluorescent chromophore, or fluorophore, called BOPHY. (umn.edu)
  • cell
  • Together with Masayasu Taki, an associate professor and Chenguang Wang, a postdoctoral research fellow in Yamaguchi's group, they optimized the structure of the fluorescent dye for live cell imaging. (innovations-report.com)
  • Please
  • If you are interested in commercial development rights using IRDye infrared dyes, please contact Business Development . (licor.com)
  • further
  • However, dyes for AC systems will have to be added using special tools to prevent the further loss of refrigerant when looking for a leak. (acdelco.com)