• Flow-mediated dilation (FMD) refers to dilation (widening) of an artery when blood flow increases in that artery. (wikipedia.org)
  • Introduction: Flow mediated-dilation (FMD) is a non- invasive test of endothelial function based on shear stress- dependent nitric oxide secretion causing vasodilation. (actapress.com)
  • Flow mediated dilation after 5-minute cuff occlusion and post-deflation shear rate were assessed. (actapress.com)
  • The flow mediated dilation (FMD) test is the most commonly utilized, non-invasive, ultrasound assessment of endothelial function in humans. (jove.com)
  • The flow-mediated dilation, or FMD test, can be used to answer key questions in the cardiovascular field, with the potential for standardized clinical monitoring of vascular function in patients. (jove.com)
  • In light of the current methodological developments in flow-mediated dilation (FMD) testing and therecognition that oxidative stress may play an important role in regulating this process, the present study sought to: (1) compare flow-mediated dilation (FMD) following 5 and 10 min of forearm cuff occlusion, and (2) evaluate the role of oxidative stress on vasodilation, both distal and proximal to the cuff. (ulster.ac.uk)
  • Betik AC, Luckham VB, Hughson RL (2004) Flow-mediated dilation in human brachial artery after different circulatory occlusion conditions. (ulster.ac.uk)
  • Chem 272:21420-21426 Green D (2005) Point: flow-mediated dilation does reflect nitric oxide-mediated endothelial function. (ulster.ac.uk)
  • Finally, earlier vascular abnormalities such as endothelial dysfunction in the peripheral arteries, detected as reduced flow-mediated dilation of the brachial artery, are useful in the research setting and as surrogate endpoints in clinical trials and have also been suggested for their possible clinical use in the future. (biomedcentral.com)
  • The aim of this study was to compare B-mode and echo tracking methods to assess endothelium-dependent flow-mediated dilation (FMD). (umn.edu)
  • Subclinical markers of cardiovascular disease among police officers: a longitudinal assessment of the cortisol awakening response and flow mediated artery dilation. (cdc.gov)
  • Objective: To examine the association of the cortisol awakening response (CAR) with change in brachial artery flow-mediated dilation (FMD%) in police officers over a seven-year period. (cdc.gov)
  • Flow-mediated dilation was assessed using brachial artery duplex ultrasonography. (who.int)
  • Officers with higher post-traumatic stress disorder (PTSD) symptoms had a nearly two-fold reduction in brachial artery flow-mediated dilation, indicating greater impairment of endothelial function (physiologic dysfunction of the normal biochemical processes carried out by the cells which line the inner surface of blood vessels) than officers with fewer PTSD symptoms. (cdc.gov)
  • Flow-Mediated Dilatation of the Brachial Artery for Assessing Endothelial Dysfunction in Children with Moyamoya Disease. (physiciansweekly.com)
  • Flow-mediated dilatation (FMD) of the brachial and radial arteries is an important research tool for assessment of endothelial function in vivo, and is nitric oxide (NO) dependent. (edu.au)
  • Bellien J, Iacob M, Gutierrez L, Isabelle M, Lahary A, Thuillez C, Joannides R (2006) Crucial role of NO and endothelium-derived hyperpolarizing factor in human sustained conduit artery flowmediated dilatation. (ulster.ac.uk)
  • Black MA, Cable NT, Thijssen DH, Green DJ (2008) Importance of measuring the time course of flow-mediated dilatation in humans. (ulster.ac.uk)
  • Eskurza I, Monahan KD, Robinson JA, Seals DR (2004) Effect of acute and chronic ascorbic acid on flow-mediated dilatation with sedentary and physically active human ageing. (ulster.ac.uk)
  • Flow Mediated Dilatation as a Biomarker in Vascular Surgery Research. (ox.ac.uk)
  • Flow mediated dilatation (FMD) of the brachial artery is an accepted method for non-invasive assessment of systemic endothelial function. (ox.ac.uk)
  • Sixteen healthy, nonsmoking women were studied, each on four occasions during one 24-h period (2:00 PM, 8:00 PM, 2:00 AM, and 8:00 AM). Endothelial function was assessed by ultrasound determinations of flow-mediated vasodilation (FMD%) in the brachial artery. (lu.se)
  • Agewall S, Hulthe J, Fagerberg B, Gottfridsson B, Wikstrand J (2002) Post-occlusion brachial artery vasodilatation after ischaemic handgrip exercise is nitric oxide mediated. (ulster.ac.uk)
  • The current project titled Regulation of lipid-mediated immunity in the intestine aimed to explore the mechanisms regulating lipid-mediated immunity in the intestine. (europa.eu)
  • Taking this into consideration, this project has focussed in understanding the mechanisms controlling lipid-mediated immunity by examining the ILC-NKT cell crosstalk. (europa.eu)
  • as well as the study of the role of ILC3s on lipid-mediated immunity (Aim 2). (europa.eu)
  • As mentioned above, the project aimed to investigate the mechanisms regulating lipid-mediated immunity in the intestinal mucosa by examining the crosstalk between ILCs and NKT cells. (europa.eu)
  • Immune mediated hemolytic anemia (IMHA), also known as auto-immune mediated hemolytic anemia (AIHA, is a disease in which the body's immune system, which is designed to attack and kill germs, attacks and kills the body's own red blood cells. (petplace.com)
  • IMHA may also be known as pure red cell aplasia (PRCA) or Evans syndrome (if it coexists with immune-mediated thrombocytopenia). (petplace.com)
  • In a recent study published in the Journal of Hepatology , researchers reported that the coronavirus disease 2019 (COVID-19) vaccination could elicit a distinct T cell-dominant immune-mediated hepatitis. (news-medical.net)
  • The phosphatidyl inositol 3-kinase (PI3K)/Akt pathway was involved in this ubiquitin-proteasome-mediated degradation of PDCD4. (plos.org)
  • Pulsatile shear stress induces ubiquitin-proteasome-mediated degradation of PDCD4 via a PI3K/Akt pathway in HUVECs. (plos.org)
  • CRISPRi genetic interaction analysis revealed Retro-2 activity resembles disruption of the transmembrane domain recognition complex (TRC) pathway, which mediates post-translational ER-targeting and insertion of tail-anchored (TA) proteins, including SNAREs required for retrograde transport. (elifesciences.org)
  • The control of cellular water flow is mediated with the aquaporin (AQP) category of membrane proteins. (healthanddietblog.info)
  • The very best studied exemplory case of this is actually the legislation of AQP2 translocation in individual kidney cells, which would depend on vasopressin-mediated activation of proteins kinase A with the G protein-coupled receptor, vasopressin V2 receptor (15). (healthanddietblog.info)
  • Within this research, we combined laser (-)-Epicatechin IC50 beam scanning confocal microscopy of chimeras of AQP1 with green fluorescent proteins (AQP1-GFP), calcium mineral imaging, and mutagenesis to determine that AQP1 translocation underpins the rules of cellular drinking water flow, as assessed by adjustments in cell quantity. (healthanddietblog.info)
  • Expected announcement of the position is spring 2023, and the project will focus on liquid-liquid phase separation mediated by phosphorylated intrinsically disordered proteins utilizing computer simulations in combination with SAXS. (lu.se)
  • Reference text: Acree LS, Comp PC, Whitsett TL, Montgomery PS, Nickel KJ, Fjeldstad AS, Fjeldstad C, Gardner AW (2007) The influence of obesity on calf blood flow and vascular reactivity in older adults. (ulster.ac.uk)
  • 5) Transforming DNA is internalized in single strand form and is protected from degradation by DprA and RecA (6), which then mediate transformation (7). (elifesciences.org)
  • Superficial femoral artery FMD in response to distal arterial occlusion for a period of 5 min is predominantly mediated by NO in healthy men and in the extremely deconditioned legs of SCI individuals. (edu.au)
  • Size-Mediated Effects of Water-Flow Velocity on Riverine Fish Species" by A. Del Signore, H. J. R. Lenders et al. (umass.edu)
  • We present a pollen flow model for maize ( Zea mays ), a major staple crop in Africa. (nature.com)
  • We conclude that the overall genetic composition of maize, in this and similar agricultural contexts, will be strongly influenced both by self-organised ecological factors (pollen flow), and by socially mediated intervention (seed recycling and sharing). (nature.com)
  • While highly specific relationships between some plants and their hummingbird pollinators probably evolved to reduce this type of heterospecific pollen flow, these relationships may break down in severely disturbed areas. (usf.edu)
  • This study looked at hummingbird-mediated pollen flow across a primary cloud forest-pasture ecotone in Monteverde, Costa Rica. (usf.edu)
  • If heterospecific pollen flow is acting as a major limiting factor of reproductive success for hummingbird-pollinated plants located along a forest edge, then even forest species that continue to be visited by their pollinators after fragmentation may be at risk, as specific pollinator plant interactions are disrupted. (usf.edu)
  • Gene flow in agricultural crops is important for risk assessment of genetically modified (GM) crops, particularly in countries with a large informal agricultural sector of subsistence cultivation. (nature.com)
  • Use the color flow mode to confirm the location of the artery, considering the direction of the transducer when interpreting the color and pulsatility to ensure the assessment of the artery and not the vein. (jove.com)
  • As an additional factor contributing to gene flow, we present data on seed saving and sharing among farmers that live in the same communities. (nature.com)
  • iii) modeled rates of pollen-mediated gene flow showed extensive mixing of germplasm between fields and farms and iv) as a result, segregation of GM and non-GM varieties is not likely to be an option in these systems. (nature.com)
  • Maize gene flow occurs through cultivator determined seed selection and mixing as well as through pollen transfer between individual plants and fields. (nature.com)
  • Gene flow occurs between all sexually compatible plants of maize types, i.e. in land races, commercial hybrids and eventual wild relatives 4 . (nature.com)
  • Once herbicide-resistant weeds evolve, they can be spread by pollen and/or seed movement, known as pollen- and seed-mediated gene flow, respectively. (unl.edu)
  • Gene flow via vegetative propagule has rarely been addressed, but could be an important avenue for certain weed species. (unl.edu)
  • Reproductive biology differs markedly among weed species, as does the potential for gene flow. (unl.edu)
  • Pollen-mediated gene flow at a distance could allow the spread of rare herbicide-resistant alleles and favor the evolution of multiple herbicide-resistant biotypes through the accumulation of different resistant genes in an individual weed or weed population. (unl.edu)
  • The speaker will discuss examples of common waterhemp, Palmer amaranth, and giant ragweed to demonstrate the role of gene flow in transfer of herbicide-resistant alleles. (unl.edu)
  • Pollen-mediated gene flow from glyphosate-resistant common waterhemp (Amaranthus rudis Sauer): consequences for dispersal of resistance genes. (unl.edu)
  • Neither gene appearance nor indirect, receptor-mediated translocation can describe the direct legislation of AQPs which may be necessary to react to the quickly changing extracellular environment on a period scale of secs. (healthanddietblog.info)
  • The stromal cell requirement for androgen-mediated effects was confirmed in vivo by experiments using chimeric animals created by bone marrow transplantation in which androgen receptor expression was restricted to either the stromal or lymphoid cells of the bone marrow. (jci.org)
  • In conclusion, we have demonstrated in vivo that carrier-mediated hepatic uptake of octreotide is inhibited by TCA and DBSP and that the CL up obtained in vivo is comparable with the CL up obtained in vitro in isolated hepatocytes and primary cultured hepatocytes. (aspetjournals.org)
  • Ample evidence shows that pro-atherosclerotic disturbed flow induces sustained activation of atherogenic genes in endothelial cells to promote their oxidation, inflammation, cell cycle progression and proliferation, whereas pulsatile shear stress tends to maintain endothelial cells in a quiescent and less proliferative state with a low level of oxidation and inflammation [16] , [17] . (plos.org)
  • Contact-mediated FGF-FGFR binding induces bidirectional signaling, which, in turn, promotes ASP and source cells to polarize cytonemes toward each other and reinforce signaling contacts. (biorxiv.org)
  • A model of the tectal circuitry predicts that these two cellular properties mediate sensitivity to a wide range of dynamic spatiotemporal stimuli, including moving stimuli, but not to static stationary stimuli in a tectal neuron. (nature.com)
  • These experiments suggest that effects of androgens on developing B cells are mediated through androgen receptors in bone marrow stromal cells. (jci.org)
  • Furthermore, because calcium mineral is definitely a pluripotent and ubiquitous second messenger in natural systems, the finding of its part in the rules of AQP translocation offers ramifications for varied physiological and pathophysiological procedures, aswell as providing a conclusion for the quick rules of drinking water flow that's essential for cell homeostasis. (healthanddietblog.info)
  • The regulation of salivary flow is primarily through the autonomic system and, most importantly, the parasympathetic division. (medscape.com)
  • Mediated cross-border communication is a scholarly field in communication studies and refers to any mediated form of communication in the course of which nation state or cultural borders are crossed or even get transgressed and undermined (e.g., world news , satellite television , transnational media events ). (wikipedia.org)
  • To evaluate the influence of food supplements with fatty acid omega 3 on the remission of a neurogenic inflammation denoted as centrally mediated chronic myalgia. (bvsalud.org)
  • In the present study, our aim was to determine the time-dependent, ER-mediated apoptotic and autophagy induction of purvalanol in HCT 116 colon cancer cells. (spandidos-publications.com)
  • The hyperaemic flow response during the first 45 s after cuff deflation was lower in both groups during infusion of L-NMMA, but the effect of L-NMMA on FMD persisted in both groups after correction for the shear stress stimulus. (edu.au)
  • Membranes circulate in response to flows in the water surrounding them, but cell membranes are reinforced by a cytoskeletal network of protein filaments which modifies their fluid properties, making their behavior complex and challenging to predict. (aps.org)
  • The book explains the influence of culture on all forms of communication behavior, be it personal, mediated or mass communication. (springer.com)
  • An at least implicit common feature to almost all of the aforementioned topics is their general interest in answering the question to what extent nationally, culturally or otherwise defined media systems influence each other, converge or whether they can pertain distinct identities under conditions of mediated cross-border communication. (wikipedia.org)
  • Citation: Ding Z, Cao J, Shen Y, Zou Y, Yang X, Zhou W, Guo Q and Huang C (2018) Resveratrol Promotes Nerve Regeneration via Activation of p300 Acetyltransferase-Mediated VEGF Signaling in a Rat Model of Sciatic Nerve Crush Injury. (vinomis.com)
  • En face co-immunostaining of the mouse aortic arch revealed a low level of PDCD4 in endothelial cells undergoing pulsatile shear stress. (plos.org)
  • Vascular endothelial cells, as a monolayer in direct contact with the flowing blood, bear the most of the wall shear stresses and have important homeostatic functions in response to stress [16] . (plos.org)
  • Thus, GPI-anchored FGF organizes both source and recipient cells and self-regulates its cytoneme-mediated tissue-specific dispersion and signaling. (biorxiv.org)
  • To investigate whether leukocyte-expressed PSGL-1 is mediating L-selectin-dependent rolling, we reconstituted lethally irradiated wild-type mice with PSGL-1 −/− bone marrow cells. (rupress.org)
  • In the 1950s, studies on mediated cross-border communication started to increasingly stress its assumed function as development and modernization prompter ( development communication ), not least due to the dozens of countries in Asia, Africa, and South America who gained their political independence at that time. (wikipedia.org)
  • Cell flow responses regulate diverse processes such as blood pressure, bone density, and neural growth. (aps.org)
  • Taken together, we have provided evidences that long-term exposure to psychosocial stress promotes mucosal inflammation and mast cell-mediated barrier dysfunction in the rat bowel. (nih.gov)
  • Moreover, we determined that during purvalanol-mediated ER stress, autophagic machinery was also activated prior to apoptotic cell death finalization. (spandidos-publications.com)
  • Our findings demonstrate that PKM2 promotes tumor progression and galectin-9-mediated immunosuppression via NF-κB signaling inhibition in HNSCC, which bridges metabolism and immunosuppression. (researchsquare.com)
  • Human and mediated communication around the world is a well-written, insightful and much-needed introduction to the global field of media and communication that will appeal to students, teachers and researchers alike. (springer.com)
  • Atherosclerosis plaques preferentially develop at arterial branches and curvatures under low and oscillatory or even static shear stress induced by disturbed blood flow as opposed to in straight parts, featuring protective unidirectional pulsatile shear stress [14] , [15] . (plos.org)
  • The purpose of this study is to explore the relationship between the nature of computer-mediated communication technology and virtual team learning and creativity from a flow theory perspective. (learntechlib.org)
  • The findings of this study suggested that flow experience is associated with perceived characteristics of the computer software as well as with team-related creativity and learning outcomes. (learntechlib.org)
  • Besides conventional SAXS measurements or sample environments, addition of instrumentation as stopped-flow devices could bring new information to the study. (lu.se)
  • We use model membranes, microfluidics and microscopy to investigate how fundamental properties of supported membranes change when flow is applied to them. (aps.org)
  • Astrocyte-mediated control of cerebral blood flow. (bvsalud.org)
  • Therefore, the enhanced cytotoxic effect of GEF under AAS culture conditions is thought to be mediated by atypical necroptosis. (spandidos-publications.com)
  • An ASNA1 point mutant identified using CRISPR-mediated mutagenesis abolishes both the cytoprotective effect of Retro-2 against ricin and its inhibitory effect on ASNA1-mediated ER-targeting. (elifesciences.org)
  • Mediated cross-border communication is considered as becoming increasingly important both as a real world phenomenon and field of research as there has been a steady strengthening of the conditions of globalization and media innovations that offer fast and low-cost forms of cross-border communication since the second half of the twentieth century. (wikipedia.org)
  • The survey results, supplemented by interviews with a smaller group of journalists who frequently contact government agencies, form the basis of our 2015 report, Mediated Access . (ucsusa.org)
  • Thematically, research is often concerned with the political dimension of mediated cross-border communication. (wikipedia.org)
  • Throughout the time, technological innovations such as satellite television or the Internet and the expansion of media markets across national borders have further stimulated research interest in mediated cross-border communication. (wikipedia.org)
  • The propaganda operations of the great powers in the twentieth century's two world wars are often considered to have been the initiating driving forces for sustained scholarly interest into mediated cross-border research. (wikipedia.org)