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  • regimens
  • Morphometric examination of neurofilament-labeled axons in the spinal cord of CR-EAE animals showed that both flecainide treatment regimens resulted in significantly higher numbers of axons surviving the disease (83 and 98% of normal) compared with controls (62% of normal). (docme.ru)
  • The study consists of 2 parts (Part A and Part B). Part A has an open-label, randomized, multi center design to evaluate the feasibility of administration of inhaled flecainide in two dosing regimens. (clinicaltrials.gov)
  • Serum
  • As with tricyclic overdose, sodium bicarbonate probably works to offset the sodium channel blocking effects of the drug, in addition to alkalinizing the serum and thus increasing the protein bound portion of flecainide as well as helping to dissociate the drug from myocytes. (emra.org)
  • sodium
  • Here, we examine the ability of a sodium channel-blocking agent, flecainide, to reduce axonal degeneration in an experimental model of MS, chronic relapsing experimental autoimmune encephalomyelitis (CR-EAE). (docme.ru)
  • disorders
  • These findings indicate that flecainide and similar agents may provide a novel therapy aimed at axonal protection in MS and other neuroinflammatory disorders. (docme.ru)
  • medical
  • As you review the electronic medical record, a handful of pill bottles are given to you that were found on scene, including flecainide and ondansetron. (emra.org)