Flavonoids5
- The compound is of little direct practical importance, but susbstituted derivatives, the flavones and flavonoids are a large class of nutritionally important natural products. (wikipedia.org)
- Therefore, herein we evaluate seven flavonoids divided into three subclasses, isoflavone (genistein), flavone (apigenin and luteolin) and flavonol (fisetin, kaempferol, myricetin, and quercetin), for COVID-19 treatment using cell-based assays and in silico calculations validated with experimental enzymatic data. (fiocruz.br)
- Flavones are a subclass of flavonoids that were tied to lower rates of stroke in a recent analysis of the Nurses' Health Study. (citylimitschiropractic.com)
- But only flavones were linked to a significant decrease in strokes, and none of the flavonoids were associated with a decrease in hemorrhagic strokes. (citylimitschiropractic.com)
- It has been estimated that in the Dutch diet a subset of flavonoids (flavonols and flavones) provide 23 mg per day. (jigsawhealth.com)
Apigenin1
- Flow cytometric analysis showed that the flavones chrysin and apigenin were able to reduce the cell surface expression of FcεRI in human basophilic KU812 cells. (elsevierpure.com)
Ginkgo Flavone Glycosides1
- The extraction yields 24% ginkgo flavone glycosides and 6% terpenes (the key constituents) from a 50-to-1 concentration. (vitanetonline.com)
Citrus Flavones1
Flavanones1
- Inhibition of Proinflammatory Cytokine Release by Flavones and Flavanones from the Leaves of Dracaena steudneri Engl. (ac.ke)
Chromone2
- Flavone is an organic compound with the formula C6H4OC3H(Ph)O. A white solid, flavone is a derivative of chromone with a phenyl (Ph) substituent adjacent to the ether group. (wikipedia.org)
- Flavone (2-phenyl chromone) is a well-known plant flavonoid, but its bioactivity has been little explored. (molcells.org)
Inhibitors1
- In this study novel bisindolylmethanes and flavones were synthesized to identify potential inhibitors for bacterial infection, cancer, and diabetes. (uitm.edu.my)
Derivatives2
- One hundred twenty-nine (129) bisindolylmethane derivatives (Schiff base, thiourea, sulfonamide, and hydrazone) and 43 flavone derivatives (hydrazone and ether) were synthesized, evaluated for various in vitro bioactivities, and analyzed through computational studies to identify possible inhibition mechanisms. (uitm.edu.my)
- Flavones derivatives 1-4 with a C-3′/4′ methylenedioxy substituent led to a substantial increase in the production of IL-1β and GM-CSF out of 4 pro-inflammatory cytokines relative to LPS control. (ac.ke)
Chrysin3
- Suppression of inflammatory response by chrysin, a flavone isolated from Potentilla evestita Th. (unisa.it)
- Therefore, in this study, we set out to investigate and characterize the effects of chrysin in classical models of inflammation reasoning that this would expand our knowledge on the pharmacological properties of this flavone. (unisa.it)
- These findings suggest that the flavone chrysin isolated from P. evestita Th. (unisa.it)
Luteolin1
- Luteolin (3',4',5,7-tetrahydroxyflavone) is a flavone with a yellow crystalline appearance present in numerous plants such as broccoli, green chili, and carrot. (gastrores.org)
Synthesis1
Isoflavone2
- Isomeric with flavone is isoflavone, where the phenyl group is adjacent to the ketone. (wikipedia.org)
- along with three known compounds Kaempferol 3- O -a-L-rhamnopyranosyl-(1®2)-b-D-glucopyranoside, (B) and Mearnsetin-3- O -a-L-rhamnopyranoside (C) Gehuain(isoflavone) (D). The compound A was characterized as 5, 7, 8-trihydroxy-6, 4'-dimethoxy flavone-7- O -a-L-rhamnopyranosyl-1®4)- O -b-D-xylopyranosyl-(1®4)--galactopyranoside by various chemical degradations and spectral analysis. (ijpsr.com)
COMPOUND2
- This compound belongs to the class of organic compounds known as flavones. (drugbank.com)
- Our results indicate that flavone is an active nematicidal compound that should be further investigated with the aim of developing a potent drug against B. xylophilus. (molcells.org)
Anticancer1
- In the current research, molecular docking investigation was conducted on some flavone-based arylamides as anticancer drug candidates via V600E-BRAF inhibition with the help of docking software Molegro Virtual Docker. (springeropen.com)
Medicinal2
- Objective Phellinus igniarius is a kind of rare medicinal fungi, its flavone can be used as medicine. (ifoodmm.cn)
- This paper deals with the significance and importance of medicinal plants.New flavone glycoside A, m.p. 222-224 o C, m.f. (ijpsr.com)
Targets1
Purification1
- This application note features the purification of five active ingredients found in over-the-counter (OTC) drugs including caffeine, glafenine, ketoprofen, flavone, and fenofibrate (Figure 1), by a preparative purification workflow with confirmation using a compact mass spectrometer. (advion.com)
Juices1
- A synergistic combination of analytical techniques was developed for the simultaneous determination of the three most biologically active chemical families in citrus juices: methoxylated flavones, coumarins, and furanocoumarins. (tmu.edu.tw)
Chemistry1
- Yano, S , Tachibana, H & Yamada, K 2005, ' Flavones suppress the expression of the high-affinity IgE receptor FCεRI in human basophilic KU812 cells ', Journal of Agricultural and Food Chemistry , vol. 53, no. 5, pp. 1812-1817. (elsevierpure.com)
Yield2
- This research was to optimize liquid culture medium for flavone fermention.Methods Taking the mycelia flavone yield of Phellinus igniarius as index, the liquid culture medium was optimized with L 9 (3 4 ) orthogonal test. (ifoodmm.cn)
- corn flour 3%+ wheat bran 7%, peptone 2%, KH 2 PO 4 0.10%, MgSO 4 0.15%, mycelia flavone yield of Phellinus igniarius was 212.35 mg/L. Conclusion Liquid culture medium optimized will have certain significance for guiding flavone's industrialized production. (ifoodmm.cn)
Found2
- The present study mas carried out in order to investigate the in vivo biotransformation and excretion of the flavone, tangeretin, found in citrus fruits, by analysing urine and faeces samples from rats after repeated administration of 100 mg/kg body weight/day tangeretin. (ku.dk)
- Sudachitin is a polymethoxylated flavone found in the peel of Citrus sudachi, a unique specialty citrus fruit in Tokushima Prefecture, Japan. (tokushima-u.ac.jp)
Biological1
- Flavones consist of an attractive category of natural products possessing several biological activities (Zhao et al. (springeropen.com)
High2
- We examined the effect of flavones on the expression of the high-affinity IgE receptor FcεRI, which plays a central role in the IgE-mediated allergic response. (elsevierpure.com)
- In extracts of the seagrass Zostera marina, collected in coastal waters of West-Norway, fourteen different flavones and high amounts of rosmarinic acid were identified. (uib.no)
Important1
- Bisindolylmethane and flavone are well-known natural product scaffolds having important pharmacophores and they have gained tremendous interest owing to their remarkable potency and activity profile towards various target diseases. (uitm.edu.my)
Properties1
- Jérémy Gordon Grands Crus and Flavones, negociant in wines invite you to discover a selection of more than 100 properties available En Primeurs or ready to be delivered from the châteaux and our warehouse. (grandscrusbordeaux.com)
Reduce1
- The two flavones were shown to reduce the level of ERK1/2 phosphorylation. (elsevierpure.com)
Test1
- On formalin test, the flavone at dose of 10.0 mg/kg i.p. displayed its maximum analgesic and anti-inflammatory effect on both early (35.67 +/- 7.88%) and late phase (50.57 +/- 5.36%) and similarly displayed at 4 h a significant anti-inflammatory effect in carrageenan-induced paw oedema. (unisa.it)
Risk1
- They discovered that people who consumed less flavones had an increased risk of ischemic strokes. (citylimitschiropractic.com)
Cells1
- Moreover, the level of mRNA expression of the FcεRI α and γ chains also decreased when the cells were cultured with the two flavones. (elsevierpure.com)