• Thus icatibant (Firazyr ® ), a bradykinin B2 receptor antagonist, has proven to be an effective and more targeted treatment option and has been approved for the treatment of acute attacks of HAE. (dovepress.com)
  • The FDA has approved icatibant (Firazyr - Shire), a selective bradykinin B2 receptor antagonist, for treatment of acute attacks of hereditary angioedema (HAE). (medicalletter.org)
  • The selective bradykinin B2 receptor antagonists segment consists of only one approved product - Firazyr. (dailybn.com)
  • FIRAZYR is a bradykinin B2 receptor antagonist and thereby has the potential to have a pharmacodynamic interaction with ACE inhibitors where FIRAZYR may attenuate the antihypertensive effect of ACE inhibitors. (firazyr.com)
  • Berinert® (C1 esterase inhibitor, human) and Icatiban (Firazyr) are indicated for the treatment of acute abdominal or facial attacks of moderate to severe hereditary angioedema (HAE). (aohq.ca)
  • FDA Approves Shire's Firazyr (icatibant injection) for Acute Attacks of Hereditary Angioedema (HAE)" (Press release). (wikipedia.org)
  • Firazyr is an FDA-approved medication given by subcutaneous injection to treat hereditary angioedema (HAE). (universaldrugstore.com)
  • On Oct. 26, 2017, Shire announced that the European Commission granted approval of Firazyr (icatibant injection) for treating hereditary angioedema (HAE) attacks, or hives, in adolescents and children aged two years and older. (pharmtech.com)
  • FIRAZYR ® (icatibant injection) Prescribing Information. (firazyr.com)
  • If your symptoms continue or come back, you may repeat your FIRAZYR injection at least 6 hours apart. (firazyr.com)
  • Icatibant, sold under the brand name Firazyr, is a medication for the symptomatic treatment of acute attacks of hereditary angioedema (HAE) in adults with C1-esterase-inhibitor deficiency. (wikipedia.org)
  • FIRAZYR is indicated for the treatment of acute attacks of hereditary angioedema (HAE) in adults 18 years of age and older. (firazyr.com)
  • FIRAZYR is a medicine used to treat acute attacks of hereditary angioedema (HAE) in adults 18 years of age and older. (firazyr.com)
  • There are currently multiple products approved by the FDA for preventing and treating hereditary angioedema (HAE) attacks, including numerous generic versions of Takeda Pharmaceuticals U.S.A., Inc.'s Firazyr. (mmitnetwork.com)
  • See how starting your patients on FIRAZYR with OnePath gives them access to product support services. (firazyr.com)
  • When you begin therapy on FIRAZYR and have enrolled in OnePath, you will be connected with a dedicated Patient Support Manager who works with you to help ensure you can access your prescribed treatment, in addition to providing other services. (firazyr.com)
  • Patients who develop angioedema symptoms after receiving stroke medication, and are not responsive to first-line angioedema therapy, may benefit from Firazyr (icatibant), a recent case report suggests. (angioedemanews.com)
  • In the EU, the approval by the European Commission (July 2008) allows Jerini to market Firazyr in the European Union's 27 member states, as well as Switzerland, Liechtenstein and Iceland, making it the first product to be approved in all EU countries for the treatment of HAE. (wikipedia.org)
  • Jerini Receives European Commission Approval for Firazyr (Icatibant) in the Treatment of HAE" (Press release). (wikipedia.org)
  • Given the potential for airway obstruction during acute laryngeal HAE attacks, patients should be advised to seek medical attention in an appropriate healthcare facility immediately in addition to treatment with FIRAZYR. (firazyr.com)
  • Takeda's leading HAE therapies include Cinryze (plasma derived) used as a preventative, Takhzyro (monoclonal antibody) used as a preventative or rescue therapy, and Firazyr (small-molecule) used strictly as a rescue treatment for breakthrough attacks. (biotechwinners.com)
  • Do not use more than 3 doses of FIRAZYR in a 24-hour period. (firazyr.com)
  • In een onderzoek waarbij 39 gezonde volwassen mannen en vrouwen behandeld werden met 30 mg om de 6 uur (3 doses om de 3 dagen met in totaal 9 doses), werden geen klinisch significante veranderingen vastgesteld ten opzichte van de uitgangswaarden wat betreft de basale en GnRH-gestimuleerde spiegels van geslachtshormonen bij zowel de vrouwen als de mannen. (cybele.be)
  • Hierdoor kan behandeling met hoge doses effecten hebben op het innestelingsproces in de baarmoeder en de verdere stabiliteit van de baarmoeder tijdens de vroege zwangerschap. (cybele.be)
  • Deze effecten op de baarmoeder manifesteren zich ook in een laat stadium van de zwangerschap, wanneer icatibant een tocolytisch effect heeft dat leidt tot vertraging van de bevalling bij ratten en een toename van foetale nood en perinatale sterfte bij hoge doses (10 mg/kg/dag) [SKP Firazyr inj 03 2013]. (cybele.be)
  • The information in this section of FIRAZYR.com is intended for US healthcare professionals only. (firazyr.com)
  • You and your healthcare provider will decide if FIRAZYR is right for you. (firazyr.com)
  • If you have an HAE attack of the throat (laryngeal attack) , inject FIRAZYR and then go to the nearest hospital emergency room right away. (firazyr.com)