• Thirteen individuals with FPC (6.1%) underwent surgical resection for a suspected PRL, but only four (1.9%) had high-risk lesions (ie, high-grade intraductal papillary mucinous neoplasms or grade 3 pancreatic intraepithelial neoplasms). (medscape.com)
  • INTRODUCTION Since the 1st description more than three decades ago1, intraductal papillary mucinous neoplasm (IPMN) of the pancreas has become widely recognized as one of the most common cyst-forming pancreatic neoplasms, and several variants of intraductal neoplasms have been described including the gastric, intestinal, or pancreatobiliary subtypes2C9. (opioid-receptors.com)
  • 2 Moreover, up to 10% of patients with intraductal papillary mucinous neoplasms (IPMNs), which are pre-malignant lesions, may be initially incorrectly diagnosed with CP. (practicalgastro.com)
  • In addition, other diagnostic systems also for urachal carcinomas that are not adenocarcinomas have been proposed. (wikipedia.org)
  • New insights emerged last decade that enriched our knowledge regarding the biological behavior of appendiceal neuroendocrine tumors (NETs), which range from totally benign tumors less than 1cm to goblet cell carcinomas which behave similarly to colorectal adenocarcinoma. (wjgnet.com)
  • The literature repeatedly describes difficulties in diagnosing PMCS, especially when attempting to differentiate the metastases from mucinous carcinomas of other origins. (asploro.com)
  • Mucinous skin carcinomas are mostly seen in the head and neck region and isolated specimens from this area should raise suspicion for a PMCS. (asploro.com)
  • Type I tumors include low-grade serous, low-grade endometrioid, clear cell and mucinous carcinomas and type II include high-grade serous, high-grade endometrioid and undifferentiated carcinomas. (biomedcentral.com)
  • With recent advancements in pathology, gene expression profiling, identification of subtypes and various modalities available for exploring the GI tract, it has become possible to find the precise origin of mucinous tumors. (thieme-connect.de)
  • The World Health Organization (WHO) classification is more detailed and, in addition to the adenocarcinoma, describes other gastric tumors of lower frequency, taking into consideration histological characteristics as well as and molecular phenotype. (medconsonline.com)
  • The 2 most common solid tumors to harbor NRG1 fusions are KRAS wild-type pancreatic adenocarcinoma and non-small cell lung cancer, specifically mucinous adenocarcinoma, Carrizosa says. (onclive.com)
  • women with mixed histologies including mucinous tumors combined with endometrioid, serous, clear-cell, and/or other histologic types were excluded. (biomedcentral.com)
  • However, as no other primary tumor could be detected at that time, a Primary Mucinous Carcinoma of the Skin (PMCS) was also debated. (asploro.com)
  • We wondered whether the worse prognosis associated with mucinous histology is also valid when age, tumor grade, substage of disease, and extent of RD are matched with serous histology in women with stage III EOC who have undergone primary CRS followed by standard intravenous paclitaxel plus carboplatin chemotherapy. (biomedcentral.com)
  • Collins K , Segura S, Hwang M. Endocrine cell micronests in an ovarian mucinous borderline tumor: a potential diagnostic pitfall for microinvasion. (iu.edu)
  • Adenocarcinoma ex-goblet cell carcinoid (AdexGCC) was considered a neuroendocrine adenocarcinoma, despite majority of tumor cells being negative for conventional neuroendocrine markers such as chromogranin and synaptophysin. (gastrores.org)
  • This is an open label Phase 1b/2 study to evaluate the efficacy and safety of ACR-368 as monotherapy or in combination with ultralow dose gemcitabine in participants with platinum-resistant ovarian carcinoma, endometrial adenocarcinoma, and urothelial carcinoma based on Acrivon's OncoSignature® test status. (uclahealth.org)
  • The mucinous acini are lined by columnar cells filled with abundant pale, foamy cytoplasm to the extent of nearly occluding the acinar lumen and contain small basal nuclei without conspicuous nucleoli. (medscape.com)
  • 3Type A tunnel clusters Type A tunnel clusters are characterized by a lobulated proliferation of small,closely packed glands that are lined by columnar mucinous epithelium. (fliphtml5.com)
  • Serum concentrations were higher in patients with Sp17 tissue expression, and the highest concentrations were noted among patients with serous and clear cell adenocarcinomas. (biomedcentral.com)
  • The purpose of this case-control study was to compare the prognoses of women with stage III mucinous ovarian carcinoma (MOC) who received maximal or optimal cytoreduction followed by paclitaxel plus carboplatin chemotherapy to those of women with stage III serous epithelial ovarian cancer (EOC) treated in the similar manner. (biomedcentral.com)
  • Although clear cell type is categorized in indolent type, it is known to show relatively strong resistance to carboplatin and paclitaxel regimen and thus poor prognosis compared to serous adenocarcinoma, especially in advanced stages. (biomedcentral.com)
  • E) Serous adenocarcinoma. (mrcoggoal.com)
  • While there was no significant difference in overall rate of neoplasm between complicated and uncomplicated appendicitis, NET rate was significantly higher in uncomplicated appendicitis while Adenocarcinoma rate was significantly higher in complicated appendicitis. (sglaresearchfoundation.org)
  • Most of this classification is based on the histological characteristics of tumours seen in surgical or needle biopsy, and is primarily based on light microscopy, although immunohistochemistry and electron microscopy findings are provided when necessary. (ersjournals.com)
  • Surgical management is en bloc resection of bladder, urachal remnant, and umbilicus. (wikipedia.org)
  • For resection specimens, new concepts are introduced such as adenocarcinoma in situ (AIS) and minimally invasive adenocarcinoma (MIA) for small solitary adenocarcinomas with either pure lepidic growth (AIS) or predominant lepidic growth with ≤ 5 mm invasion (MIA) to define patients who, if they undergo complete resection, will have 100% or near 100% disease-specific survival, respectively. (qxmd.com)
  • We describe the case of a 67-year-old female patient who presented with an unclear swelling on the right supraclavicular neck, two years after resection of a mucinous carcinoma on the right mastoid. (asploro.com)
  • A 67-year-old female presented with a suspicious swelling on the right supraclavicular region two years after resection of a mucinous carcinoma on the surface of the skin overlying the right mastoid. (asploro.com)
  • Pseudomyxoma Peritonei ( PMP ) is a more common name given to the "jelly belly" syndrome caused by mucinous adenoma and mucinous adenocarcinoma. (cancerindex.org)
  • Data queried for this analysis include colorectal adenocarcinoma (2010-2011) from the Surveillance, Epidemiology, and End Results Program (SEER) database. (oncotarget.com)
  • Immunohistochemical stains are usually less helpful in the histopathological differential diagnosis of urachal adenocarcinomas. (wikipedia.org)
  • Diagnosis was established with histology or follow-up. (hindawi.com)
  • Pneumoconioses: pathological findings and differential diagnosis, in particular silicosis and asbestosis. (unibo.it)
  • Available gross photographs and descriptions as well as all histologic sections were re-evaluated to confirm the diagnosis and further characterize the spectrum of histology findings. (opioid-receptors.com)
  • This new classification strategy is based on a multidisciplinary approach to diagnosis of lung adenocarcinoma that incorporates clinical, molecular, radiologic, and surgical issues, but it is primarily based on histology. (qxmd.com)
  • It is difficult to differentiate hyperplastic polyps from other polyps by conventional light endoscopy and histology is needed for diagnosis 3 , 4 . (openaccesspub.org)
  • Yocum BP , Hwang M, Mesa H, Collins K . Differential Diagnosis of Cystic Lesions of the Spleen: A Review of Clinical, Imaging and Pathological Findings. (iu.edu)
  • Haemoperitoneum seen at laparotomy suggested a diagnosis of ectopic pregnancy .The diagnosis of ruptured corpus luteum cyst (RCLC) was made only after histology. (bvsalud.org)
  • 7 ] Previously, there was a dilemma in finding the exact pathology because of limited diagnostic techniques and knowledge about the disease. (thieme-connect.de)
  • Full knowledge of normal anatomy, histology and embriology are necessary to understand Anatomic Pathology. (unibo.it)
  • To address advances in oncology, molecular biology, pathology, radiology, and surgery of lung adenocarcinoma, an international multidisciplinary classification was sponsored by the International Association for the Study of Lung Cancer, American Thoracic Society, and European Respiratory Society. (qxmd.com)
  • Benign pathology of the prostate gland, and prostate histology and anatomy are dealt with in the ''[[prostate gland]]'' article. (librepathology.org)
  • For instance, in one institutional review five cases diagnosed asinvasive adenocarcinoma over a 14-year period were reclassified as benign mimics (1).Although a variety of immunoperoxidase stains have been tried, ultimately therecognition of benign pseudoneoplastic glandular lesions of the cervix rests upon theirdistinctive histologic features. (fliphtml5.com)
  • Adenocarcinoma is the most common histologic type of lung cancer. (qxmd.com)
  • Squamous carcinoma was by far the most common histological type (82.2%), distantly followed by adenocarcinoma (12.8%) and mesenchymal/mixed Mullerian malignancies comprising 0.01% (5 cases). (smjonline.org)
  • [4] , [5] While squamous carcinoma remains overwhelmingly preponderant in the developing world, its frequency has slightly declined in the developed world, with relatively increased in the prevalence of adenocarcinoma. (smjonline.org)
  • Squamous carcinoma mostly occurred in a slightly older age group (fifth to seventh decades), than adenocarcinoma (fourth to sixth decades). (smjonline.org)
  • This report demonstrates the limitations of currently used histopathological and immunohistochemical differentiation in metastatic mucinous carcinoma. (asploro.com)
  • In this study, we have investigated the clinical characteristics of malignancy during pregnancy in Japan, with the goal that our findings will contribute to the earlier detection and better management of malignant diseases during pregnancy. (biomedcentral.com)
  • The Cowper's glands comprise mucinous glands with small to absent central lumina, seen just deep to prostatic urethral mucosa. (medscape.com)
  • Mucinous metaplasia of prostatic acini: This condition features cells that contain abundant mucin-filled cytoplasm that mimic Cowper's glands (bulbourethral glands). (medscape.com)
  • many of these benign yet floridly proliferative lesions have been mistaken for invasive adenocarcinoma. (fliphtml5.com)
  • 2Introduction The distinction between benign proliferative glandular lesions of the endocervixand well-differentiated invasive cervical adenocarcinoma continues to be problematic, ashighlighted by the number of reports in the literature considering this diagnostic issue.Interestingly, the relatively recent recognition of a number of potential mimics ofinvasive adenocarcinoma of the endocervix underscores the likelihood that in the pastmany of these benign yet floridly proliferative lesions have been mistaken for invasiveadenocarcinoma. (fliphtml5.com)
  • Fifty-four cases (41.9%) had histologically normal appendices, while 75 cases (58.1%) had various histopathologically demonstrable lesions ranging from acute appendicitis (the most frequent with 27%) to neoplasia (one case of mucinous adenocarcinoma). (bvsalud.org)
  • 1 ] Mucinous ovarian cancer (MOC) is a rare subtype of malignant ovarian cancer. (thieme-connect.de)
  • The terms BAC and mixed subtype adenocarcinoma are no longer used. (qxmd.com)
  • The most frequent subtype of HP is the one with microvesicular mucinous cells named mivrovesicular hyperplastic polyp (MVHP) this type is characterized with the presence of small droplet mucin in cytoplasm of the most cells. (openaccesspub.org)
  • Appendiceal goblet cell carcinoid (GCC) and adenocarcinoma ex-goblet cell carcinoid (AdexGCC) have previously been described as two entities in a spectrum of neoplasms showing both glandular/mucinous and neuroendocrine differentiation [ 1 ]. (gastrores.org)
  • Benign Mimics of Invasive Adenocarcinoma of the Cervix Tunnel Clusters Microglandular Hyperplasia Mesonephric Hyperplasia Endocervical Glandular Hyperplasias Arias-Stella ReactionTunnel Clusters Fluhmann first introduced the term "tunnel cluster" in his description of thehistology of the endocervix (2;3). (fliphtml5.com)
  • Tunnel clusters have been separated by Fluhmann into two subcategories: Type Aand Type B. Although type A and B tunnel clusters are often intermixed, their distinctionis important as they each pose their own relatively unique problems in the discriminationfrom invasive adenocarcinoma. (fliphtml5.com)
  • If the cancer originates from the stomach glandular tissue, the medical term for such a condition is gastric adenocarcinoma, or gastric cancer. (medconsonline.com)
  • The region of columnar esophageal metaplasia is considered the "cancerization field" in which esophageal adenocarcinoma (EAC) develops [ 3 - 5 ]. (jcancer.org)
  • This new adenocarcinoma classification is needed to provide uniform terminology and diagnostic criteria, especially for bronchioloalveolar carcinoma (BAC), the overall approach to small nonresection cancer specimens, and for multidisciplinary strategic management of tissue for molecular and immunohistochemical studies. (qxmd.com)
  • These findings suggest that these two different types of ovarian cancers develop along different molecular pathways. (biomedcentral.com)
  • A large global registry study primarily evaluated patients with lung cancer who harbored NRG1 fusions, and findings showed that these patients experienced poorer outcomes than those without these fusions, Carrizosa adds. (onclive.com)
  • Using a variety of other markers, we were unable to detect neither significant morphological nor immunohistochemical characteristics that distinguished the lesion from a mucinous carcinoma of mammary origin. (asploro.com)
  • Studies evaluating rate and histology of appendiceal neoplasms between complicated and uncomplicated appendicitis include small number of patients. (sglaresearchfoundation.org)
  • Based on intra-operative findings, 1943 (38%) had complicated appendicitis and 3175 (62%) had uncomplicated appendicitis. (sglaresearchfoundation.org)
  • Incidental appendectomy in the absence of contraindications is an option because although the gross appearance of the appendix may be unremarkable, histology may demonstrate appendicitis or other pathologies such as endometriosis, neoplasia, obstruction by appendicoliths, or parasites. (webop.com)
  • As compared to the previous edition, changes include a better definition of pre-invasive lesion, a reclassification of adenocarcinoma, the description of two new tumour types as variants of large cell carcinoma, large cell neuroendocrine carcinoma (LCNEC) and basaloid carcinoma, and a new class called pleomorphic carcinoma. (ersjournals.com)
  • The Cowper's glands (bulbourethral glands) can be recognized microscopically as a dimorphic population of mucinous acini and excretory ducts, arranged in a lobular pattern with interspersed fibrous tissue and variable amount of striated muscle bundles (see the image below). (medscape.com)
  • The common admixture of type A and B tunnelclusters, in combination with the predominantly lobulated architecture, absence ofdesmoplasia and lack of deep, widely infiltrative glands helps distinguish it fromadenoma malignum.Type B tunnel clusters Type B tunnel clusters also have a lobular architecture, but are composed ofdilated glands lined by cuboidal or flattened epithelium and filled with inspissated,mucinous secretions. (fliphtml5.com)
  • Our findings were consistent with most published reports in Nigeria and sub-Saharan Africa but somewhat at variance with the developed world where cervical cancer is much less common and afflicts a slightly older age group. (smjonline.org)
  • This is in keeping with ultrastructural studies in GCCs that showed the presence of abundant mucinous vacuoles, in comparison with the extremely difficult to locate, occasional membrane-bound, electron-dense granules [ 3 ]. (gastrores.org)
  • Mohs surgery is a surgical technique used to treat various skin cancers that allows precise microscopic control of the margins by utilizing tangentially cut frozen-section histology. (medscape.com)
  • Mucinous cystadenocarcinoma account for about a fifth of appendix tumours, these produces mucin (a jelly-like substance). (cancerindex.org)
  • While tunnel clusters are usually an incidentalhistologic finding, they can sometimes be florid and cause a gross abnormality that isstriking to both the clinician and the pathologist. (fliphtml5.com)
  • Amidst the mucinous acini are excretory ducts lined by low cuboidal cells. (medscape.com)
  • According to the Laurén classification, gastric adenocarcinomas are divided into the intestinal, diffuse and indeterminate (having an uncommon histology) type. (medconsonline.com)
  • International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma. (qxmd.com)
  • The mastoid skin lesion was originally diagnosed by two separate institutes to be most likely a metastatic mucinous carcinoma. (asploro.com)
  • Objective To evaluate the clinicopathological features and survival outcomes of mucinous ovarian cancer (MOC) patients in an Asian population. (thieme-connect.de)
  • In order to further evaluate the overall validity of Sp17 as a biomarker for EOC, more complete data are needed with regards to Sp17 tissue expression across the different histologies, grades, and stages. (biomedcentral.com)