• Air pollution exposure results in increased oxidative stress, linked to poor cardiovascular outcomes. (confex.com)
  • However, the association of a previous psychiatric diagnosis of anxiety or depression, or only such self-reported symptoms, with cardiovascular outcomes and mortality post-MI has not been previously examined in the same nationwide cohort. (lu.se)
  • In recent years, the mechanism(s) by which excess body weight produces adverse cardiovascular outcomes has attracted interest, with one potential pathway being the dysfunction of adipose tissue. (nature.com)
  • Markov model with a lifetime horizon was developed to evaluate economic and health outcomes for atorvastatin drugs for the prevention of cardiovascular diseases for a cohort of 1,000 patients. (ac.ir)
  • Originally published 17 Aug 2018 https://doi.org/10.1161/CIRCOUTCOMES.117.004464 Circulation: Cardiovascular Quality and Outcomes. (ahajournals.org)
  • The present findings demonstrated that BNP either as numerical or logarithmic value is not a reliable predictor for one-year outcomes (renal function improvement and blood pressure control) after revascularization, but could be a valuable biomarker in the assessment of major adverse renal events and MACE. (romanianjournalcardiology.ro)
  • CONCLUSIONS: Adopting a pharmacist-involved team-based hypertension model could substantially improve BP control and cardiovascular outcomes in the United States. (cdc.gov)
  • Sensitivity analyses under recessive and additive models for the two outcomes with adequate data (major adverse cardiovascular events and stent thrombosis) produced results in the same direction but with larger effect sizes than the dominant model. (ahrq.gov)
  • The aim of this study was to create a decision tree model with machine learning to predict the outcomes of COVID-19 cases from data publicly available in the Philippine Department of Health (DOH) COVID Data Drop. (who.int)
  • The model incorporated population-representative data from India on multiple risk factors that affect myocardial infarction and stroke mortality, including hypertension, hyperlipidemia, diabetes, coronary heart disease, and cerebrovascular disease. (who.int)
  • To provide evidence of the relationship of Mediterranean diet (MD) on incidence/mortality for cardiovascular disease (CVD), coronary/ischemic heart disease (CHD)/acute myocardial infarction (AMI) and stroke (ischemic/hemorrhagic) by sex, geographic region, study design and type of MD score (MDS). (nih.gov)
  • We did not identify direct evidence that community salt substitution reduces cardiovascular morbidity or mortality. (givewell.org)
  • One randomized controlled trial (RCT) of salt substitution, conducted in elderly men rather than all members of a community, reports a 41% reduction in cardiovascular mortality. (givewell.org)
  • However, this indirect evidence suggests a smaller effect, a 2.5% reduction in cardiovascular mortality. (givewell.org)
  • Conclusions Our findings suggest BA measures may be complementary in predicting risk for mortality and age-related disease. (deepdyve.com)
  • Today, cardiovascular disease is one of the main causes of mortality and disability in most developed and developing countries. (ac.ir)
  • Serum potassium levels have been positively associated with cardiovascular mortality, but little is known about the association with cancer mortality and death due to other causes. (biomedcentral.com)
  • A positive linear association was found for all-cause mortality (HR per mmol/L 1.6, 95% CI 1.4-1.8), and for cardiovascular (HR per mmol/L 1.4, 95% CI 1.1-1.7) and other cause mortality (HR per mmol/L 1.7, 95% CI 1.3-2.2). (biomedcentral.com)
  • These findings suggest that serum potassium level appears to predict long-term mortality in healthy middle-aged men, and it might imply future surveillance strategies for individuals with high serum potassium levels. (biomedcentral.com)
  • The importance of potassium in cardiovascular mortality or all-cause mortality has been examined more extensively. (biomedcentral.com)
  • The decision tree model prioritized age and history of hospital admission as predictors of mortality. (who.int)
  • Together with evidence from a meta-analysis of RCTs demonstrating that blood pressure-lowering drugs reduce the risk of high-burden cardiovascular diseases, we believe this constitutes moderately strong evidence that the intervention reduces the risk of cardiovascular events and deaths. (givewell.org)
  • Salt substitution is inexpensive and likely reduces the risk of high-burden cardiovascular diseases, yet its ongoing cost constrains its cost-effectiveness. (givewell.org)
  • Effect modification by individual-level SES, ethnicity and co-morbidities with cardiovascular disease, respiratory diseases, diabetes, lung cancer and dementia, and ethnicity will be evaluated by entering interaction terms into the model. (healtheffects.org)
  • The prediction of the major causes of deaths all over the world at all ages shows that 61% of deaths are due to chronic diseases, of which 30% is due to cardiovascular disease. (ac.ir)
  • The aim of this study was to assess the cost‑utility analysis of atorvastatin for the prevention of cardiovascular diseases using the Markov model. (ac.ir)
  • It was not possible to perform an analysis adjusted for cardiovascular diseases, because only 1 study each for BBs and ACEIs, respectively, had adjusted data. (worldallergy.org)
  • The quality of evidence showing that the use of BBs and ACEI increases the severity of anaphylaxis is low owing to differences in the control of confounders arising from the concomitant presence of cardiovascular diseases. (worldallergy.org)
  • The Oslo Ischemia Study is a comprehensive health survey established in 1972, aimed to examine risk factors for coronary heart disease and other cardiovascular diseases in a healthy middle-aged male population. (biomedcentral.com)
  • The pathophysiology of aortic stenosis is however similar to other cardiovascular diseases that fiber intake has been associated with. (lu.se)
  • ABSTRACT Chronic (noncommunicable) diseases, such as cardiovascular disease, stroke, cancer and diabetes mellitus, are a global public health problem that is increasing, particularly in developing countries. (who.int)
  • The purpose of the study was to discuss about new and ongoing epidemiologic transition, the so called "Corona and Misery" phenomenon and some of its aspects for population changes and epidemiologic transition particularly in domain of Cardiovascular Diseases (CVD). (jimc.ir)
  • Published literature regarding epidemiologic trans- ition and cardiovascular diseases, as well as cardiovascular diseases and COVID-19, including cardiovascular changes in 2020, were reviewed. (jimc.ir)
  • Cardiovascular diseases constitute a global health care crisis in which eHealth can provide novel solutions to improve the efficiency and reach of self-management support for patients where they most need it: their homes and communities. (utwente.nl)
  • Objective: The primary objective of this review is to facilitate a holistic interpretation of eHealth projects aimed at providing self-management support of cardiovascular diseases in the natural setting of patients, thus priming the use of remote monitoring technologies. (utwente.nl)
  • Conclusions: This review is important because it aims to create a holistic understanding of a multidisciplinary topic at the crossroads of eHealth, cardiovascular diseases, and self-management. (utwente.nl)
  • Our results will show how useful this method can be in bridging the multidisciplinary gap of eHealth research and development, to inform and advance the importance of holistic approaches, while showcasing this approach for the case of self-management in cardiovascular diseases. (utwente.nl)
  • The sample consisted of 334 (14%) of the 2354 pharmacies in Ankara, and 24 essential medicines for cardiovascular diseases, diabetes, chronic respiratory diseases, and palliative care, adopted from the WHO Model List of Essential Medicines (2021). (who.int)
  • [ 5 , 7 ] Although the underlying mechanisms are complex, the chronic inflammatory state and microbial burden in people with periodontal disease may predispose them to cardiovascular diseases in ways proposed for other infections. (medscape.com)
  • Methods and Findings A microsimulation model was developed to quantify the differential effects of various tobacco control measures and pharmacological therapies on myocardial infarction and stroke deaths stratified by age, gender, and urban/rural status for 2013 to 2022. (who.int)
  • Eligible studies were of case-control or cohort design, reported on cardiovascular events (predominantly myocardial infarction) with cyclooxygenase 2 inhibitor, NSAID use, or both with nonuse/remote use of the drugs as the reference exposure. (nih.gov)
  • Background Mathematical modeling of cardiovascular magnetic resonance perfusion data allows absolute quantification of myocardial blood flow. (essex.ac.uk)
  • We validated the accuracy of each model in detecting reduced myocardial blood flow in stenotic vessels versus gold-standard invasive methods. (essex.ac.uk)
  • Distributed parameter modeling showed excellent accuracy in detecting reduced myocardial blood flow in all stenotic vessels. (essex.ac.uk)
  • Cardioprotective effects of Hmox1 were demonstrated in experimental models of myocardial infarction (MI). (springer.com)
  • Furthermore, identifying new biomarkers of cardiovascular risk has the potential to refine early-life prevention strategies, before atherosclerosis becomes established. (bmj.com)
  • Considering the limitation of studies investigating the relationship between T. gondii and cardiovascular biomarkers, this study was focused on assessing the association of T. gondii to nine cardiovascular biomarkers. (mdpi.com)
  • Objective To examine if self reported toothbrushing behaviour is associated with cardiovascular disease and markers of inflammation (C reactive protein) and coagulation (fibrinogen). (bmj.com)
  • Surveys were linked prospectively to clinical hospital records, and Cox proportional hazards models were used to estimate the risk of cardiovascular disease events or death according to oral hygiene. (bmj.com)
  • Results There were a total of 555 cardiovascular disease events over an average of 8.1 (SD 3.4) years of follow-up, of which 170 were fatal. (bmj.com)
  • In about 74% (411) of cardiovascular disease events the principal diagnosis was coronary heart disease. (bmj.com)
  • Conclusions Poor oral hygiene is associated with higher levels of risk of cardiovascular disease and low grade inflammation, though the causal nature of the association is yet to be determined. (bmj.com)
  • Over the past two decades, there has been an increasing interest in the possible link between dental disease, specifically periodontal disease, and cardiovascular disease. (bmj.com)
  • 1 Inflammation plays an important role in the pathogenesis of atherosclerosis, and markers of low grade inflammation have been consistently associated with a higher risk of cardiovascular disease. (bmj.com)
  • 2 Consequently, contributing factors associated with inflammation and chronic infections, including oral infections such as periodontal disease, have been investigated to explain the relation between dental disease and cardiovascular disease. (bmj.com)
  • 4 5 6 7 Systemic inflammation could represent the underlying mechanism that links oral health and cardiovascular disease. (bmj.com)
  • Previous smaller epidemiological studies that have examined the association between oral health and cardiovascular disease have generally used clinical assessments to identify periodontal disease. (bmj.com)
  • Objective To develop, validate, and evaluate a new QRISK model to estimate lifetime risk of cardiovascular disease. (bmj.com)
  • Subjects Patients aged 30-84 years who were free of cardiovascular disease and not taking statins between 1 January 1994 and 30 April 2010: 2 343 759 in the derivation dataset, and 1 267 159 in the validation dataset. (bmj.com)
  • Cardiovascular disease is the leading cause of premature death and a major cause of disability in the UK. (bmj.com)
  • 1 National policies now support targeting of interventions to reduce risk of cardiovascular disease among high risk patients. (bmj.com)
  • Despite the rise in co-morbid cardiovascular disease risk factors like hyperlipidemia and hypertension in low- and middle-income countries, tobacco control is likely to remain a highly effective strategy to reduce cardiovascular deaths. (who.int)
  • Further mechanistic studies are underway to elaborate these findings using organoids and disease animal models. (cdc.gov)
  • Cardiovascular disease is the most common cause of death worldwide, and high blood pressure is one of its primary causes. (givewell.org)
  • Given that cardiovascular disease is the most common cause of death worldwide, and high blood pressure is one of its primary causes, there is likely to be extensive room for more funding for this intervention. (givewell.org)
  • Cardiovascular disease is the leading cause of death worldwide, with an especially devastating impact in low-to-medium income countries. (revespcardiol.org)
  • Cardiovascular disease has been elevated to this position by a combination of factors that include urbanization and its attendant effects, such as obesity, a sedentary lifestyle, changes in dietary habits, and smoking. (revespcardiol.org)
  • Given the enormous extent of the problem and the complexity of its causes, which include cultural, social, political, and health care factors, an equally sophisticated and comprehensive strategy is required to combat cardiovascular disease on a global scale. (revespcardiol.org)
  • Thus, our efforts should be concentrated not only on cardiovascular disease treatment and prevention, but also on health promotion and primordial prevention. (revespcardiol.org)
  • In this review, we present different strategies yielding encouraging results at the population level, from childhood until old age, that aim to protect against the challenges facing the scientific community when combating cardiovascular disease. (revespcardiol.org)
  • Background There is a need to explore common activity patterns undertaken by workers and the association between these activity profiles and cardiovascular disease (CVD). (iwh.on.ca)
  • Methods Study Sample The Framingham Heart Study (FHS) is a community-based longitudinal cohort study initiated in 1948 to study determinants of cardiovascular disease (CVD) and its risk factors. (deepdyve.com)
  • Avoidance of overweight from adolescence onwards is likely important for cardiovascular disease prevention. (nature.com)
  • The best model to predict CV death included low blood pressure, estimated glomerular filtration rate ≤ 60 mL/min, peripheral oedema, previous HF hospitalization, ischaemic HF, chronic obstructive pulmonary disease, elevated N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP), and troponin (c‐index = 0.73). (gla.ac.uk)
  • Based on the results of this study, it is recommended that cardiologists use atorvastatin in the prevention of cardiovascular disease. (ac.ir)
  • We modeled the impacts of 5 hypothetical therapies affecting different patient types: curative gene therapy for a childhood disorder, highly effective hepatitis C virus therapy, disease-modifying Alzheimer disease therapy, and cardiovascular disease therapy for both rare genetic and higher-risk prior cardiovascular event populations. (ajmc.com)
  • We constructed disease-specific models, modifying best-available Markov analysis estimates for standard-of-care state transition rates, utilities, and costs. (ajmc.com)
  • In modeling the potential impacts of 5 hypothetical new transformative therapies representing diverse patient types, clinical intervention models, and disease burdens, we found substantial and varying gaps between initial and downstream payer impacts. (ajmc.com)
  • Further investigations are warranted to determine OSA's direct influence on cardiovascular disease. (qxmd.com)
  • The distributed parameter model can also be used for absolute quantification but has not been applied in patients with coronary artery disease. (essex.ac.uk)
  • We also performed analysis using both models of single bolus data obtained from five patients with coronary artery disease and findings were compared against independent invasive coronary angiography and fractional flow reserve. (essex.ac.uk)
  • OBJECTIVES: Research suggests that persons who are aware of the risk factors for cardiovascular disease (CVD) are more likely to engage in healthy behaviors than persons who are not aware of the risk factors. (cdc.gov)
  • Cardiovascular disease: Chicken or the egg? (scienceblogs.com)
  • Experience with changing rates of cardiovascular disease, obesity, diabetes and cancer shows this clearly. (biomedcentral.com)
  • The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention. (cdc.gov)
  • World Health Organization (WHO), are often selected on and hospitalizations may reduce when cardiovascular the basis of disease prevalence, evidence for efficacy and patients use lifelong medication consistently (9) . (who.int)
  • To undertake a systematic review and meta-analysis of controlled observational studies to compare the risks of serious cardiovascular events with individual NSAIDs and cyclooxygenase 2 inhibitors. (nih.gov)
  • We subsequently conducted a systematic review of the handling and reporting of treatment use in prognostic model studies in cardiovascular medicine. (biomedcentral.com)
  • The value of metaethnography in contrast to other systematic review methods is that its synthesis approach seeks to generate a new understanding of a topic, while preserving the social and theoretical contexts in which findings emerge. (utwente.nl)
  • 1] entitled Global estimates for the lifetime cost of managing HIV: a systematic review describes the lifetime costs of HIV care and treatment, by country income levels, perspective of the cost analysis, and modeling methods. (cdc.gov)
  • Large studies with long-term follow-up confirmed the utility of CACS as a predictor of cardiovascular risk in populations. (bmj.com)
  • Seventy-nine articles (26%) excluded treated individuals from their analysis, 80 articles (26%) modelled treatment as an outcome, and of the 155 articles that developed a model, 86 (55%) modelled treatment use, almost exclusively at baseline, as a predictor. (biomedcentral.com)
  • The accuracy of the model was 86.8%, while lnBNP alone as an unique predictor of MACE, provided 76.3% of the accuracy of the multi-parametric model. (romanianjournalcardiology.ro)
  • abstract = "Background Cardiovascular development is vital for embryonic survival and growth. (vtt.fi)
  • Methods: Patients older than 70 years of age scheduled for elective cardiovascular surgery using CPB were enrolled. (mdpi.com)
  • METHODS: In this cross-sectional study, we used harmonized data from 109,184 adults (aged 18-97 years) from the SALURBAL (Salud Urbana en America Latina/Urban Health in Latin America) project. (bvsalud.org)
  • Methods: We will use Noblit and Hare's metaethnography approach to review and synthesize researchers' and practitioners' reports on how they applied frameworks, models, and theories in their projects. (utwente.nl)
  • Methods: The participants (N=1064-1348, born between 1962-1977) came from the population-based Cardiovascular Risk in Young Finns Study. (helsinki.fi)
  • Background We simulated tobacco control and pharmacological strategies for preventing cardiovascular deaths in India, the country that is expected to experience more cardiovascular deaths than any other over the next decade. (who.int)
  • Conclusions Smoke-free laws and substantially increased tobacco taxation appear to be markedly potent population measures to avert future cardiovascular deaths in India. (who.int)
  • After a median follow-up of 30 years (interquartile range 21.2-38.7), 1736 deaths were observed, of which 494 were cancer deaths, 688 cardiovascular deaths, and 536 deaths related to other causes. (biomedcentral.com)
  • Predictive model ing could greatly help low- and have been 1 681 925 recoveries and 31 810 deaths. (who.int)
  • 8 C reactive protein and fibrinogen are sensitive markers used to evaluate the inflammatory status of an individual, and the results of prospective longitudinal studies indicate that these markers might be useful predictors for future cardiovascular events in various populations. (bmj.com)
  • Although these interactions remain to be further examined in humans, the physiological functions of taurine appear to be inconsistent with the adverse cardiovascular symptoms associated with excessive consumption of caffeine-taurine containing beverages. (researchgate.net)
  • Fredrickson was unable to reproduce the math behind her research published with Losada and in a later response the mathematical models for the paper were formally withdrawn. (wikipedia.org)
  • Fredrickson and Losada's use of nonlinear dynamics modelling, taken from fluid dynamics, to derive these values, has been strongly criticised by Nicholas Brown, Alan Sokal, and Harris Friedman, who point out numerous fundamental mathematical errors in the article (see Losada line). (wikipedia.org)
  • Fredrickson has agreed that the mathematical modelling is "questionable", but stands by the more general idea that a high emotional positivity-to-negativity ratio is beneficial. (wikipedia.org)
  • This investigation has examined a possible role for the renin-angiotensin system as well as body mass and insulin values in mediating these cardiovascular and renal aspects of the hypertension syndrome. (scienceopen.com)
  • These findings suggest that in overweight patients cardiovascular and renal values depend chiefly on body weight and insulin, but that in normal weight hypertensives the renin-angiotensin system may play the major role. (scienceopen.com)
  • These specific conditions in the oral cavity may create foci of infection that can affect many other vital systems, such as the cardiovascular and renal systems. (medscape.com)
  • Background: The incidence of delirium is high in older patients undergoing cardiovascular surgery with cardiopulmonary bypass (CPB). (mdpi.com)
  • A decline in age-specific incidence of dementia, at least in high-income countries, is theoretically possible, driven by changes in exposure to suspected developmental, lifestyle and cardiovascular risk factors for dementia [ 6 ]. (biomedcentral.com)
  • Sedation and analgesia dosing and titration were associated with delayed awakening, incidence of clinical seizures, and survival, but the causal relation of these findings cannot be proven. (lu.se)
  • By demonstrating distal organ oxidative stress response after pulmonary exposure, we describe a potential pathophysiologic mechanism for cardiovascular and hepatic dysfunction by air pollution exposure. (cdc.gov)
  • Because exposure to cardiovascular risk factors occurs from early ages, this strategy must be expanded and adjusted throughout the life of an individual. (revespcardiol.org)
  • The second success was in the ambient air and with the time control ing SHS exposure (American that the WHO FCTC developed that the individual spends in contact Society of Heating, Refrigerating evidence-based model language with it. (who.int)
  • Several remaining areas of uncertainty limit our confidence in this estimate, and it is possible that alternative intervention models would be more cost-effective than those we considered. (givewell.org)
  • Cox proportional hazards models tested the association of each BA estimate with each outcome adjusting for covariates. (deepdyve.com)
  • Thus, oral infections might add to the inflammatory burden of the individual and result in increased levels of cardiovascular risk based on serum C reactive protein and fibrinogen concentrations as a consequence of the systemic inflammatory response subsequent to low grade chronic infections. (bmj.com)
  • 0.04) remained in the model as independent predictors of LVM. (scienceopen.com)
  • Separately for never or currently/formerly smoking participants, we estimated the association between educational level (as a proxy for socioeconomic status, modeled in 4 categories) and incident lung cancer using Cox proportional hazards models. (who.int)
  • Indeed, women have been reported to develop initially motor symptoms, with men exhibiting mainly cardiovascular dysfunction ( 13 ). (frontiersin.org)
  • Ignoring treatments in prognostic model development or validation can affect the accuracy and transportability of models. (biomedcentral.com)
  • We aim to quantify the extent to which the effects of treatment have been addressed in existing prognostic model research and provide recommendations for the handling and reporting of treatment use in future studies. (biomedcentral.com)
  • We first describe how and when the use of treatments by individuals in a prognostic study can influence the development or validation of a prognostic model. (biomedcentral.com)
  • The use of treatments has been partly considered by the majority of CVD prognostic model studies. (biomedcentral.com)
  • Where relevant, the use of treatments should be considered in the analysis of prognostic model studies, particularly when a prognostic model is designed to guide the use of certain treatments and these treatments have been used by the study participants. (biomedcentral.com)
  • Future prognostic model studies should clearly report the use of treatments by study participants and consider the potential impact of treatment use on the study findings. (biomedcentral.com)
  • An important part of prognostic research is the development and validation of prognostic models or risk scores. (biomedcentral.com)
  • In practice, however, such prognostic models are often derived from or validated in data sets where a proportion of the individuals has received that specific treatment. (biomedcentral.com)
  • In this manuscript, we aim to provide insight into the problems that arise when treatment use is ignored when developing or validating a prognostic model. (biomedcentral.com)
  • First, we elaborate on how and when treatment use could negatively impact prognostic modelling. (biomedcentral.com)
  • Following this, we provide evidence of the scale of this issue in published studies by means of a systematic literature review of the reporting and handling of treatment use in cardiovascular prognostic model research. (biomedcentral.com)
  • We conclude with suggestions for the handling and reporting of treatment use in prognostic model research. (biomedcentral.com)
  • COVID-19 data sets be used to create more robust prognostic models. (who.int)
  • Of the 10% of patients in the validation cohort classified at highest risk with either the lifetime risk model or the 10 year risk model, only 18 385(14.5%) were at high risk on both measures. (bmj.com)
  • Conclusions Compared with using a 10 year QRISK2 score, a lifetime risk score will tend to identify patients for intervention at a younger age. (bmj.com)
  • Very low or zero CACS is reassuring and clinically valuable, but age and other prevalent risk factors are major drivers of CACS, 1 such that most middle-aged or older patients in higher cardiovascular risk groups have elevated CACS. (bmj.com)
  • We aim to recruit 75 VCI patients, 60 HFpEF patients, 60 patients with severe aortic stenosis (AS) undergoing surgical aortic valve replacement as a pressure overload HFpEF model, and 200 elderly participants with mixed comorbidities to serve as controls. (unav.edu)
  • Cardiovascular and behavioral risk factors were observed more among patients with HAND compared to no-HAND. (who.int)
  • Many studies in MSA patients have already depicted cardiovascular autonomic impairments with a reduction in sympathetic and parasympathetic activities ( 6 - 9 ). (frontiersin.org)
  • Aims Heart failure (HF) patients are at high‐risk of cardiovascular (CV) events, including CV death. (gla.ac.uk)
  • Identifying patients at higher risk for each individual event may help selecting patients for clinical trials and tailoring cardiovascular therapies. (gla.ac.uk)
  • yet these models allowed the identification of patients in whom absolute CV death rates clearly outweigh non‐CV death ones. (gla.ac.uk)
  • Conclusions Risk models for predicting CV and non‐CV death allowed the identification of patients at higher absolute risk of dying from CV causes (vs. non‐CV ones). (gla.ac.uk)
  • So it's difficult to draw conclusions about patients who don't fit those metrics. (medscape.com)
  • 6 Predictive model ing may also help to inform least one positive reverse transcription-polymerase chain patients about the possible course of their il ness and reaction test of a respiratory swab. (who.int)
  • Cox proportional hazards models in the derivation cohort to derive risk equations accounting for competing risks. (bmj.com)
  • Cox proportional hazard models were used to calculate hazard ratios (HRs) with 95% confidence intervals (CIs) and adjusted for multiple confounders. (biomedcentral.com)
  • Cardiovascular autonomic failure (AF) is one of the main features which worsens dramatically the quality of life. (frontiersin.org)
  • The cardiovascular AF in MSA is thought to be mainly due to a progressive neurodegeneration of several areas involved in autonomic control of the cardiovascular system such as inter alia , cholinergic neurons in the ventrolateral ambiguous nucleus and dorsal motor nucleus of the vagus nerve ( 5 ). (frontiersin.org)
  • The findings of this study also showed that the highest cost items were hospitalization costs in the cardiac care unit (CCU). (ac.ir)
  • The aim of this study was to determine the role of Hmox1 in the monocyte/macrophage-mediated cardiac remodeling in a mouse model of MI. (springer.com)
  • the receiver operating characteristic (ROC) curve was used to evaluate the diagnostic power of the nomogram model for screening hypertension risk. (frontiersin.org)
  • Investigators also found that inhibition of inflammation can alleviate hypertension in animal models ( 5 , 6 ). (frontiersin.org)
  • OBJECTIVE: The objective of this study was to assess the potential health and budgetary impacts of implementing a pharmacist-involved team-based hypertension management model in the United States. (cdc.gov)
  • The information gained through this bed-side to bench translational approach contributes to a more complete understanding of the protein pathways dysregulated during cardiovascular development and provides novel avenues for diagnostic and therapeutic interventions, beneficial to fetuses at risk for CHDs. (vtt.fi)
  • There is some evidence to suggest increasing prevalence in East Asia, consistent with worsening cardiovascular risk factor profiles, although secular changes in diagnostic criteria may also have contributed. (biomedcentral.com)
  • Findings were overall robust across multiple sensitivity analyses. (lu.se)
  • Conclusions: Both a previous diagnosis, and present self-reported symptoms of anxiety or depression are associated with an increased risk of death and recurrent cardiovascular events in adults with first-time MI. (lu.se)
  • Results and conclusions: High depressive symptoms were cross-sectionally associated with higher paranormal thinking. (helsinki.fi)
  • Cardiovascular and non‐cardiovascular death distinction: the utility of troponin beyond N‐terminal pro‐B‐type natriuretic peptide. (gla.ac.uk)
  • We identified spleen as an important source of these cardiovascular complications in Hmox1 −/− mice. (springer.com)
  • There is growing evidence that early development of obesity increases cardiovascular risk later in life, but less is known about whether there are effects of long-term excess body weight on the biological drivers associated with the atherosclerotic pathway, particularly adipokines, inflammatory and endothelial markers. (nature.com)
  • An accumulation model best described the associations between overweight across the life course with adipokines and inflammatory markers, whereas for the endothelial markers, the sensitive period model for 60-64 years provided a slightly better fit than the accumulation model. (nature.com)
  • We also plan to update our conclusions when the findings of the Salt Substitute and Stroke Study are published. (givewell.org)
  • 2010) often employ the familiar random regression (RR) model. (researchgate.net)
  • 10% were estimated using robust Poisson regression models. (iwh.on.ca)
  • The relationship between selected dependent variables and lifetime pack-years was assessed in two models with multiple linear regression analysis. (biomedcentral.com)
  • 2) the European-wide hybrid land use regression model developed within the Effects of Low-Level Air Pollution: A Study in Europe (ELAPSE) project, providing annual concentrations of PM 2.5 , NO 2 , BC, and O 3 for year 2010. (healtheffects.org)
  • A multivariate logistic regression model using age, peak troponin, and initial ECG findings had a high discriminatory value for determining EA versus CCL X (C statistic, 0.985). (ahajournals.org)
  • I ran logistic regression models with groups of the obese (9). (cdc.gov)
  • In its simplest form, this model assumes that one can characterize the temporal trendlines of all of the subjects using straight lines about a linear mean level trend, for example, that if convergence or divergence do occur, these patterns are maintained over the entire course of a study (see Figure 1a,b). (researchgate.net)
  • The main objective of this study was to investigate the prevalence of T. gondii among adults in the United States and its association with cardiovascular health using data from the National Health and Nutrition Examination Survey (NHANES 2009-2010). (mdpi.com)
  • 2 Therefore, the purpose of this study was to elucidate the impact of caffeine and taurine on arrhythmogenesis in a sensitive whole-heart model. (researchgate.net)
  • Therefore, purpose of this study was to assess acute electrophysiologic effects of caffeine and taurine, two of the main ingredients of energy drinks, in an experimental whole-heart model. (researchgate.net)
  • Data Conclusion This study could demonstrate the feasibility of PCASL to identify splenic switch-off during adenosine perfusion MRI, both by qualitative and quantitative assessments. (unav.edu)
  • The findings of this study do not indicate that consumption of dietary fiber or fiber rich foods are associated with incident aortic stenosis. (lu.se)
  • Results and conclusion: The results of this study showed that high exhaustion was cross-sectionally associated with higher levels of paranormal thinking. (helsinki.fi)
  • This review confirms the findings from randomized trials regarding the risk of cardiovascular events with rofecoxib and suggests that celecoxib in commonly used doses may not increase the risk, contradicts claims of a protective effect of naproxen, and raises serious questions about the safety of diclofenac, an older drug. (nih.gov)
  • Diosgenin exerts diverse bioactivities, but most of its pharmacological actions are related to the management of cardiovascular disorders, such as lowering plasma total cholesterol and antithrombotic activity [ 9 ]. (hindawi.com)
  • Models adjusted for demographics, medication use, and related health conditions. (confex.com)
  • These effects may help to mitigate negative effects of PM2.5 on cardiovascular health. (confex.com)
  • However, it is possible there are opportunities to promote community salt substitution through public health regulation or other approaches , which we have not modeled yet and that may be more cost-effective. (givewell.org)
  • Cardiovascular health promotion in childhood: the si! (revespcardiol.org)
  • The findings suggest that, while higher-intensity activity may confer benefits sooner, adding more light activity or more standing, or even going to bed earlier, could improve heart health measures over time. (medscape.com)
  • The goal of evidence and draw conclusions longer than the act of smoking. (who.int)
  • We compared number of medications used, dosing, and titration among centers by using multivariable models, including common severity of illness factors. (lu.se)
  • Conclusions Our findings are consistent with results reported elsewhere (Marchioli 2003, Jenkins et al. (confex.com)
  • Researchers modeled what would happen if people swapped various amounts of one activity for another every day for a week. (medscape.com)
  • Our findings indicate and further quantify that MD exerts a protective effect on the risk of CVD. (nih.gov)
  • In addition, the fit of different life course models (sensitive periods/accumulation) were compared using partial F-tests. (nature.com)
  • Through application of innovative Distributed Simulation techniques, collaborative design, and consistent evaluation techniques from conceptual, development, and implementation stages, fully immersive simulation techniques for cardiovascular specialities are achievable and have the potential to be implemented more broadly. (biomedcentral.com)
  • An impaired HRV was observed at 12 months of age in PLP-α-syn female but not in male mice, indicative of cardiovascular AF. (frontiersin.org)
  • In conclusion, HFD-induced obese Ldlr −/− .Leiden mice develop an aberrant ITO and alterations in the spermatogenic cycle in crucial stages (stages VII and VII). (nature.com)
  • Positive emotions do not themselves generate cardiovascular reactivity, but instead quell any existing cardiovascular reactivity caused by negative emotions. (wikipedia.org)
  • Machine learning processes were used to generate, train and validate a decision tree model. (who.int)