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  • protein
  • The normal CFTR protein product is found in membranes of cells that line passageways of the lungs, liver, pancreas, intestines, reproductive tract, and skin. (studyres.com)
  • Sixty-nine protein genes and eight ORFs conserved with those found in land plant chloroplasts have also been found. (pnas.org)
  • Exosomes contain protein and genetic material and have been proposed to play a role in cellular communication whereby their contents can be transferred to other cells. (ands.org.au)
  • In protein-protein interaction network, sRNA targets tend to occupy more central positions (higher closeness centrality, p-val = 0.022) and more cliquish (larger clustering coefficient, p-val = 0.037). (biomedcentral.com)
  • As was found for the protein-protein interaction network, the targets that are regulated by the same sRNA also tend to be closely knit within the transcription-regulatory network (larger density, p-val = 0.036), and inward interactions between them are greater than the outward interactions (higher in-degree ratio, p-val = 0.023). (biomedcentral.com)
  • Modifying these residues or nucleotides has a large effect on the communication pathways in the protein:RNA complex consistent with kinetic data. (pnas.org)
  • BA-induced apoptosis requires new protein, but not RNA, synthesis, is independent of p53, and results in p21 protein accumulation in the absence of a cell cycle arrest. (aspetjournals.org)
  • We find that BA-induced apoptosis of glioma cells is characterized by a sequential requirement for new protein, but not RNA, synthesis, generation of reactive oxygen species, and caspase processing associated with poly(ADP-ribose)polymerase cleavage. (aspetjournals.org)
  • Each of the 64 different nucleotide triplets in DNA that, when transcribed into RNA , are then translated into an aminoacid in a protein. (bmj.com)
  • TTH activity (≈0.28 U/mg protein) was found in cell-free extracts of TT-grown but not of sulfur-grown cells. (frontiersin.org)
  • Genes
  • For example, the chloroplast genome of the red alga Porphyra purpurea contains over 70 new genes not found in land plant and Euglena chloroplasts ( 4 , 7 ). (pnas.org)
  • small
  • ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rfr_id=info%3Asid%2FANDS&rft.title=Next Generation Sequencing of Extracellular RNA&rft.publisher=The University of Melbourne&rft.description=Exosomes are small nanovesicles released by cells. (ands.org.au)
  • This study demonstrated that α v β 3 integrin increases survival of α v β 3 -LNCaP cells upon IR while small hairpin RNA (shRNA)-mediated knockdown of α v β 3 integrin in PC-3 cells sensitizes to radiation. (aacrjournals.org)
  • Exosomes in human semen carry a distinctive repertoire of small non-coding RNAs with potential regulatory functions. (nih.gov)
  • SE contain protected small RNAs. (nih.gov)
  • enzyme
  • The enzyme also shows a similar discrimination against single-stranded RNA. (ucsb.edu)
  • Nucleoside modifications are interesting due to their already known roles in translation fidelity, enzyme recognition, disease progression, and RNA stability. (mdpi.com)
  • Analysis
  • RNA gel blot analysis revealed that Arabidopsis ETFQO transcripts accumulated in long-term dark-treated leaves. (plantcell.org)
  • Analysis of three independent insertional mutants of Arabidopsis ETFQO revealed a dramatic reduction in their ability to withstand extended darkness, resulting in senescence and death within 10 d after transfer, whereas wild-type plants remained viable for at least 15 d. (plantcell.org)
  • long
  • In addition to these key players, many other RNA species have been identified such as long non-coding RNAs (lncRNAs), micro RNAs (miRNAs) or even enzymatic RNAs like RNase P [ 1 ]. (mdpi.com)
  • cell
  • They can be found in bodily fluids such as blood, milk, saliva and cerebrospinal fluid, and be isolated from cell culture supernatants. (ands.org.au)
  • The collection contains data from our studies sequencing exosomal RNA from a variety of sources including cell cultures, serum, plasma, milk, urine, CSF both to look at the normal content of these vesicles and also to identify potential biomarkers for the diseases we are studying. (ands.org.au)
  • Streptavidin is devised as a handle to assemble biotinylated cell penetrating peptides (e.g., transactivating transcriptional activator (TAT)), as well as an insulator between the positive charge of TAT and the dense negative charge of RNA. (ucsb.edu)
  • human
  • Human, rat and mouse cAMP phosphodiesterase isoforms (denoted PDE4D7s), as well as the DNA (RNA) encoding such polypeptides, are disclosed. (freepatentsonline.com)
  • levels
  • We find that ATF4 levels are increased in neuromelanin-positive neurons in the substantia nigra of a subset of PD patients relative to controls. (jneurosci.org)