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Amino Acid MotifsMolecular Sequence DataNucleotide MotifsAmino Acid SequenceBase SequenceBinding SitesProtein BindingProtein Structure, TertiarySequence Homology, Amino AcidSequence AlignmentConserved SequenceModels, MolecularProtein Interaction Domains and MotifsMutationTranscription FactorsHelix-Turn-Helix MotifsDNA-Binding ProteinsMutagenesis, Site-DirectedCell LineRecombinant Fusion ProteinsPromoter Regions, GeneticCloning, MolecularConsensus SequenceDNATranscription, GeneticProtein Structure, SecondarySequence Analysis, DNAProtein ConformationAlgorithmsComputational BiologyRecombinant ProteinsProteinsNuclear ProteinsPhylogenyNucleic Acid ConformationTransfectionHeLa CellsStructure-Activity RelationshipSignal TransductionSaccharomyces cerevisiaeEvolution, MolecularEscherichia coliPeptidesDNA PrimersMembrane ProteinsGene Expression RegulationHelix-Loop-Helix MotifsCarrier ProteinsSaccharomyces cerevisiae ProteinsBacterial ProteinsModels, BiologicalSoftwareSequence DeletionRNA-Binding ProteinsCOS CellsRNA, MessengerSequence Analysis, ProteinEF Hand MotifsPhosphorylationCrystallography, X-RayRepressor ProteinsAmino Acid SubstitutionModels, GeneticMutagenesisTwo-Hybrid System TechniquesRegulatory Elements, TranscriptionalRegulatory Sequences, Nucleic AcidSubstrate SpecificityPlasmidsDimerizationRNADrosophila ProteinsSequence Homology, Nucleic AcidKineticsProtein TransportComputer SimulationOligodeoxyribonucleotidesMultigene FamilyProtein FoldingLeucine ZippersPeptide FragmentsCells, CulturedCell NucleusRepetitive Sequences, Amino AcidCell MembranePoint MutationDrosophilaCytoplasmEnhancer Elements, GeneticCercopithecus aethiopsFungal ProteinsTrans-ActivatorsProtein Interaction MappingAdaptor Proteins, Signal TransducingTranscriptional ActivationCatalytic DomainPhosphoproteinsAT-Hook MotifsLigandsCysteine
SequencesSequenceHighly conservedEpithelialProteinsPatternsNecklineStructuralFabricsFindingsOccurProteinSearchAlgorithmPrecisionChestPeptideSizeAlphabetMutationsThresholdFabricPriceIdentificationBackInteractionDomainSimilarDetailResultsUniqueHumanServicesLoveInputMetalShareBackgroundTargetsVintageSlightlyNoteMadeThemesRingMajor
Sequences7
  • This is an investigation of methods for finding short motifs that only occur in a fraction of the input sequences. (aaai.org)
  • In the field of computational biology, a planted motif search (PMS) also known as a (l, d)-motif search (LDMS) is a method for identifying conserved motifs within a set of nucleic acid or peptide sequences. (wikipedia.org)
  • We find that the fission yeast homologues of Tristetraprolin/TTP and Pumilio/Puf (Zfs1 and Puf3) interact with Ccr4-Not via multiple regions within low-complexity sequences, suggestive of a multipartite interface that extends beyond previously defined interactions. (elifesciences.org)
  • Known as "destabilising motifs", these sequences attract the attention of a group of proteins called Ccr4-Not. (elifesciences.org)
  • We further used cleavage under target and release using nuclease (CUT&RUN) to identify the exact motif sequences on the genome where complexes containing YT bind in the normal and fibrotic lung epithelial. (lu.se)
  • We further identified putative TFs that are known to bind the motif sequences identified. (lu.se)
  • A group of influenza subject matter experts compiled the H5N1 Inventory of amino acid changes in viruses' genetic sequence or amino acid motifs (varying combinations of amino acid sequences) by: (1) conducting a literature review of published and publically available information on H5N1 genetic changes, and (2) using a text mining process that examined existing PubMed H5N1 publications for information about changes in the genetic makeup of H5N1 viruses. (cdc.gov)
Sequence6
  • Support for various forms of sequence motif matrices. (biopython.org)
  • A generator function, returning found hits in the given sequence with the pwm score higher than the threshold. (biopython.org)
  • Missense mutations altering a consensus PPPXY sequence of the alpha, beta or gamma subunits reproduced the increase in channel activity found in mutants in which the entire cytoplasmic C-termini are deleted. (nih.gov)
  • This proline-rich sequence, referred to as the PY motif, is known to be a site of binding by proteins bearing a WW domain. (nih.gov)
  • A helix initiation motif and a helix termination motif segment can be found at either end of the alpha-helical rod and are highly conserved in sequence between keratins. (medscape.com)
  • A superfamily of proteins that share a highly conserved MADS domain sequence motif. (bvsalud.org)
Highly conserved1
  • One motif, GASSL, is highly conserved throughout the evolution of IRF3 and 7 and located in the signal response domain. (cdc.gov)
Epithelial2
  • These channels are found at the surface of certain cells called epithelial cells in many tissues of the body, including the kidneys, where the channels transport sodium into cells. (medlineplus.gov)
  • Interestingly, we found epithelial YT signaling to be actively involved in extracellular matrix remodeling in the fibrotic lung epithelium through modulation of lysyl oxidase expression, a collagen crosslinking enzyme. (lu.se)
Proteins3
  • Many MADS domain proteins have been found in species from all eukaryotic kingdoms. (bvsalud.org)
  • However, in the mid 1990s, other proteins were also found to accumulate in the abnormal muscle fibers, and molecular genetic studies revealed several chromosomal loci. (medscape.com)
  • The coiled coil is one of most recurring structural motifs in eucarytotic proteins, found in for example transcription factors, motor and skeletal proteins. (lu.se)
Patterns1
  • The problem of identifying meaningful patterns (e.g., motifs) from biological data has been studied extensively since they play a vital role in understanding gene function, human disease, and may serve as therapeutic drug targets. (wikipedia.org)
Neckline1
  • Outlined with shimmering sequins on an intricate patterned motif, this dress reveals a high halter neckline coupled with an open back. (couturecandy.com)
Structural1
  • The phospholipid bilayer is the basic structural motif of most biological membranes. (lu.se)
Fabrics1
Findings2
  • These findings show that the three PY motifs in the C-termini of ENaC are involved in the regulation of channel activity, probably via protein-protein interactions. (nih.gov)
  • your jewelry can be all that with these Tribal Motif Findings/ Connectors . (gemmartusa.com)
Occur2
  • Call the variants of a motif that occur in the input strings as instances of the motif. (wikipedia.org)
  • Instructors looking for a graduate- tings nearly all such deaths occur in chapters collected by the editors to level textbook may find this recent older adults or adults with chronic promote community-based health addition to the preventive medicine medical conditions. (cdc.gov)
Protein3
  • The ancestral protein of IRF3 and 7 seemed to possess the DPHK motif. (cdc.gov)
  • FCHO1560-571, a synthetic water -soluble peptide , was generated from the PKB substrate motif 560PPRRLRSRKVSC571 found in the human FCHO1 protein . (bvsalud.org)
  • A classic example of a LRR is the Ribonuclease inhibitor, which adopts a horseshoe shape with the beta-strands forming a beta barrel on the inside where its protein-protein binding site is found. (lu.se)
Search4
  • Unlike local search techniques that may not reach a global optimum, the method proposed here is guaranteed to produce the motifs with greatest z-scores. (aaai.org)
  • The time complexities of most of the planted motif search algorithms depend exponentially on the alphabet size and l. (wikipedia.org)
  • The PMS problem is also known as the (l, d)-motif search (LDMS) problem. (wikipedia.org)
  • We're sorry, we couldn't find results for your search. (benbridge.com)
Algorithm1
  • For each such bucket, an expectation maximization (EM) algorithm is used to check if an (l, d) motif can be found using the l-mers in the bucket. (wikipedia.org)
Precision1
  • We first developed a method to simultaneously isolate proximal and distal lung progenitor cells from an individual mouse with the aid of a 3D printed surgical guide and found that the precision of dissecting the lung lobes affects the purity of the isolated distal progenitors and how they behave in organoid assays. (lu.se)
Chest1
  • A leisurely staple, this t-shirt is embellished with a logo and tricolour motif on the chest. (moncler.com)
Peptide2
  • peptide, a PKB kinase motif, inhibits tumor progression. (bvsalud.org)
  • FCHO1 560-571 peptide, a PKB kinase motif, inhibits tumor progression. (bvsalud.org)
Size3
  • Just follow the simple instructions included to easily measure and find a ring size at your convenience. (benbridge.com)
  • Measuring your correct and current dress size for a dress purchase is the single most important step in finding and keeping the perfect dress. (couturecandy.com)
  • Find the measurement in the size chart under circumference. (greekshops.com)
Alphabet1
  • Alternatively, the pseudocounts can be a dictionary with a key for each letter in the alphabet associated with the motif. (biopython.org)
Mutations1
  • The mutations in pachyonychia congenita are found in the genes encoding keratin 6A (KRT6A), keratin 16 (KRT16), keratin 6B (KRT6B), and keratin 17 (KRT17). (medscape.com)
Threshold1
Fabric1
  • Robert Allen Top Motif Lagoon is a cotton and polyester blended upholstery weight fabric with a gorgeous soft emerald green floral motif on canvas off white.With an amazing 50,000 double rubs, this indoor fabric will stand the test of time. (cushionsource.com)
Price1
Identification1
  • This current research project sets the basis for the identification of exact targeting mechanisms for finding therapeutics for IPF. (lu.se)
Back2
  • The novel's central motif comes from the tale of Orpheus, the great musician of Greek mythology, who charmed his way into the underworld and begged the gods with music to bring his wife back to life. (wordnik.com)
  • Designed to fit a wide range of sizes, use the press-on pull-off Velcro back panel to easily find your perfect fit. (lactationconnection.com)
Interaction1
  • We found that YT have different interaction partners in the proximal and distal lung epithelium and further identified specific YT interactions in the human fibrotic lung epithelium. (lu.se)
Domain1
  • Another motif, DPHK, is in the DNA-binding domain. (cdc.gov)
Similar2
  • Since the instances of any (l, d) motif are similar to each other, many of these instances will fall into the same bucket. (wikipedia.org)
  • What is puzzling is that the destabilising motifs that control different groups of mRNAs can be very similar, and scientists do not yet know how Ccr4-Not can tell the difference, or what triggers it to start breaking down groups of mRNAs. (elifesciences.org)
Detail1
  • The weight of any such item can be found on its detail page. (gemmartusa.com)
Results2
Unique1
  • Two unique motifs in IRF3 and 7 were identified. (cdc.gov)
Human1
  • To be more specific, self destruction as well as the mutability of human fate is a main motif of ancient Greek tragedies. (lu.se)
Services1
  • RÉSUMÉ Les saignements chez les femmes ménopausées représentent l'un des motifs les plus fréquents d'orientation vers les services gynécologiques. (who.int)
Love1
  • People get sick, they die, they find love and lose it and find it again in the same place and in unexpected places at the same time, and the timing is never quite right, because the definition of 'quite right' depends upon each individual's emotional and psychological state, a thing for which real life couldn't care less. (motifri.com)
Input2
  • Following input from the Sami Parliament and the Sami Artists' Union, Norges Bank invited seven artists to participate in a competition to design the anniversary motif on the reverse of the coin. (norges-bank.no)
  • Let the motif M of interest be an l-mer and C be the collection of all the l-mers from all the n input strings. (wikipedia.org)
Metal2
  • This sterling silver ring features the traditional Minoan Swirl Motif, which is cut into the metal. (greekshops.com)
  • Here we design a suite of ligand-stabilized metal oxide clusters and find that these modulate carbon dioxide reduction pathways on a copper catalyst, enabling thereby a record activity for methane electroproduction. (nature.com)
Share1
  • These mini-motif tops share the sweetness of the season with everyone around you -- whether you're at the hair salon, soccer field, or fall festival. (qvc.com)
Background1
Targets1
  • Consequently, motif quality is a major determinant of mRNA stability for Puf3 targets in vivo and can be used for the prediction of mRNA targets. (elifesciences.org)
Vintage1
  • The delicate milgrain contour of the vine motif provides a vintage and romantic look to the band. (jamesallen.com)
Slightly1
  • The motif may be slightly altered before coin production begins. (norges-bank.no)
Note1
  • Note that the Hamming distance between any two instances of an (l, d) motif is no more than 2d. (wikipedia.org)
Made1
  • Orvis Trout Rising Socks are made in fine merino wool and showcase our iconic motif. (orvis.com)
Themes1
  • This is brought up by my friend: How important are themes and motifs in Film Scores? (jwfan.com)
Ring1
  • Ring in the festive season with this holiday gingerbread house motif sweatshirt from Stella McCartney Kids. (stellamccartney.com)
Major1
  • This bra is designed to fit with the Motif breast shields and pumps, but will fit with most major breast pumps as well. (lactationconnection.com)