AnatomyDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesDisciplines and OccupationsHealth CareGeographicals
Pulmonary FibrosisPancreatic ExtractsMediastinitisNephrogenic Fibrosing DermopathyFibrosisScleroderma, SystemicDiatrizoateConnective Tissue DiseasesLung Diseases, InterstitialPancrelipaseLungCollagen DiseasesCholestasis, IntrahepaticPrednisoloneSkin DiseasesColonic DiseasesSclerosisBone Cysts, AneurysmalBronchoalveolar LavageAsbestosisScleromyxedemaProstanoic AcidsZeinRespiratory Function TestsPulmonary AlveoliBronchoalveolar Lavage FluidVital CapacityIdiopathic Pulmonary FibrosisPulmonary Diffusing CapacitySarcoidosisLung Volume MeasurementsTomography, X-Ray ComputedSclerosing SolutionsBiopsyPulmonary EmphysemaCholestasisLung DiseasesRadiography, ThoracicDiagnostic ErrorsGadoliniumPropylene GlycolsPrednisoneHorse DiseasesBleomycinLiver CirrhosisAutoantibodiesLipaseConfidence IntervalsSkinPulmonary EmbolismMethodsCystic FibrosisEpitheliumFibroblastsIn Situ HybridizationLymphocytesCase-Control StudiesColonSmokingCyclophosphamideLiver TransplantationNeutrophilsImmunohistochemistryMacrophagesInterleukin-8Retrospective StudiesImmunoglobulin GTransforming Growth Factor betaReference ValuesChronic DiseaseOdds RatioDrug Administration ScheduleGreat BritainDisease Models, AnimalDose-Response Relationship, DrugTreatment OutcomeBiological Markers
Cryptogenic fibrosingFrontalAlopeciaNephrogenic FibrosingPoikiloderma with tendonLung diseaseCystic fibrosisAlveolitisColonopathyInterstitial pneumoniaMediastinitisDisordersContractureDiseasesMediastinitisInterstitial lungNephrogenic fibrosingChronicPhenotypeAged 6-17 yearsNintedanibILDsPatientsCryptogenicProgressiveInflammatoryTissueYearsConditionsCases
Cryptogenic fibrosing6
  • Prognosis of cryptogenic fibrosing alveolitis. (bmj.com)
  • We have analysed retrospectively 100 consecutive patients with cryptogenic fibrosing alveolitis, who were treated with corticosteroids and followed for at least three years. (bmj.com)
  • The case notes of 200 patients with cryptogenic fibrosing alveolitis, from three regions in the United Kingdom, were reviewed, in order to determine how physicians manage this uncommon condition. (elsevierpure.com)
  • These results suggest that, in the late 1980s, there were wide variations of practice in the management of cryptogenic fibrosing alveolitis in the United Kingdom. (elsevierpure.com)
  • 3 Hypersensitivity pneumonitis and cryptogenic fibrosing alveolitis , lung diseases related to wood dust exposure, can result in pulmonary fibrosis and restrictive lung changes. (cdc.gov)
  • 1996] Occupational exposure to metal or wood dust and aetiology fo cryptogenic fibrosing alveolitis. (cdc.gov)
Frontal10
  • Frontal fibrosing alopecia, described just over 20 years ago, has become one of the most frequently seen causes of scarring alopecia at many specialist hair clinics. (skintherapyletter.com)
  • Frontal fibrosing alopecia (FFA) was first described in 1994 by Kossard as a new type of scarring alopecia. (skintherapyletter.com)
  • Various facial and extrafacial lesions have been reported in frontal fibrosing alopecia (FFA). (karger.com)
  • A . Acute hair loss on the limbs in frontal fibrosing alopecia: a clinicopathological study of two cases . (karger.com)
  • Frontal fibrosing alopecia (FFA) can cause noticeable hair loss anywhere hair grows. (wigsbyjenniferfoley.ie)
  • Frontal fibrosing alopecia is a relatively new hair loss condition that was first described in the 1990s. (stevenweissmanmd.com)
  • Though initially thought of as a rare condition, frontal fibrosing alopecia has become increasingly more common with the reported incidence increasing worldwide. (stevenweissmanmd.com)
  • It may also occur in cases of frontal fibrosing alopecia . (hairboutique.com)
  • Frontal fibrosing alopecia (FFA) is a chronic form of primary lymphocytic cicatricial alopecia characteristically involving the frontotemporal hairline and eyebrows. (mhmedical.com)
  • classic LPP, frontal fibrosing alopecia , and Lassueur Graham-Little Piccardi syndrome . (rarediseases.org)
Alopecia1
  • Fibrosing alopecia is considered to be a clinical variant of lichen planopilaris . (hairboutique.com)
Nephrogenic Fibrosing3
  • Nephrogenic Fibrosing Dermopathy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (ouhsc.edu)
  • This graph shows the total number of publications written about "Nephrogenic Fibrosing Dermopathy" by people in this website by year, and whether "Nephrogenic Fibrosing Dermopathy" was a major or minor topic of these publications. (ouhsc.edu)
  • Below are the most recent publications written about "Nephrogenic Fibrosing Dermopathy" by people in Profiles. (ouhsc.edu)
Poikiloderma with tendon2
  • At least six mutations in the FAM111B gene have been identified in people with hereditary fibrosing poikiloderma with tendon contractures, myopathy, and pulmonary fibrosis (POIKTMP). (medlineplus.gov)
  • Mutations in FAM111B cause hereditary fibrosing poikiloderma with tendon contracture, myopathy, and pulmonary fibrosis. (medlineplus.gov)
Lung disease2
  • The term "fibrosing lung disease" covers a wide variety of different and frequently life-threatening illnesses, some of which are more common while others are extremely rare. (pulmonary-fibrosis.net)
  • Inhalation of quartz (crystalline silica) can lead to the fibrosing lung disease, silicosis (Morgan and Seaton, 1984). (cdc.gov)
Cystic fibrosis2
  • Fibrosing colonopathy is a disease that arises in people with cystic fibrosis treated with high doses of pancreatic enzyme supplements. (wikipedia.org)
  • Fibrosing colonopathy is associated with high-dose use of pancreatic enzyme replacement in the treatment of cystic fibrosis patients. (nih.gov)
Alveolitis1
  • A patient with fibrosing alveolitis on prolonged cyclophosphamide treatment developed therapy-related MDS. (nih.gov)
Colonopathy1
  • Fibrosing colonopathy (FC) is a rare usually iatrogenic disease associated to shortening and fibrosis of the colon, which almost exclusively occurs as a gastrointestinal complication in patients with CF. FC is characterized by severe submucosal thickening in distal caecum and ascending colon with mild or negligible signs of inflammation and absence of other lesions evocative of Crohn's disease. (cfdb.eu)
Interstitial pneumonia1
  • Idiopathic Pulmonary Fibrosis IPF is a chronic, progressive fibrosing interstitial pneumonia of unknown cause that primarily occurs in older adults. (medscape.com)
Mediastinitis2
  • CT scanning is helpful in detecting calcification in a lung nodule (histoplasmoma) and in evaluating patients with fibrosing mediastinitis and broncholithiasis. (medscape.com)
  • The adenopathy associated with fibrosing mediastinitis demonstrates relatively low signal intensity on T2-weighted images. (medscape.com)
Disorders4
  • Localized fibrosing disorders include a spectrum of rare conditions that frequently begin in childhood. (medscape.com)
  • The causes of localized fibrosing disorders are unknown. (medscape.com)
  • Localized fibrosing disorders include several clinical and histopathological conditions that are similar to the skin involvement of systemic sclerosis , but the systemic features are absent. (medscape.com)
  • Localized fibrosing disorders are only rarely life threatening, but they can severely affect quality of life, particularly in children. (medscape.com)
Contracture1
  • Other fibrosing conditions mentioned in this article include retroperitoneal fibrosis , mediastinal fibrosis, and Dupuytren contracture . (medscape.com)
Diseases2
Mediastinitis1
  • J. Morin, A. Hirsch and P. Chamoun, "Pulmonary Artery Bypass for Fibrosing Mediastinitis," International Journal of Clinical Medicine , Vol. 1 No. 2, 2010, pp. 70-72. (scirp.org)
Interstitial lung14
  • In patients with chronic fibrosing interstitial lung disease (ILD), a progressive fibrosing phenotype (PF-ILD) may develop, but information on the frequency and characteristics of this population outside clinical trials is lacking.We assessed the characteristics and outcomes of patients with PF-ILD other than idiopathic pulmonary fibrosis (IPF) in a real-world, single-centre clinical cohort. (nih.gov)
  • Within the spectrum of fibrosing interstitial lung diseases (ILDs) is a proportion of patients who experience progression of pulmonary fibrosis despite immunomodulatory treatment, known as the progressive fibrotic phenotype . (medscape.com)
  • To identify novel plasma biomarkers of progressive fibrosing interstitial lung disease and develop a proteomic signature to predict this phenotype. (nih.gov)
  • Progressive fibrosing interstitial lung disease (ILD) is a devastating condition characterized by parenchymal scar formation, leading to deteriorating lung function and early death. (nih.gov)
  • 17 plasma biomarkers of progressive fibrosing interstitial lung disease were identified and showed consistent associations across ILD subtypes. (nih.gov)
  • Claims-based Prevalence of Disease Progression among Patients with Fibrosing Interstitial Lung Disease Other than Idiopathic Pulmonary Fibrosis in the United States. (bvsalud.org)
  • Rationale Chronic fibrosing interstitial lung disease (ILD) with a progressive phenotype is a clinical concept describing the broad group of ILDs characterized by progressive pulmonary fibrosis . (bvsalud.org)
  • The U.S. Food and Drug Administration (FDA) has agreed to review an application seeking the approval of Ofev (nintedanib) for children ages 6 to 17 with fibrosing interstitial lung diseases (ILDs). (pulmonaryfibrosisnews.com)
  • If approved, Ofev would be the first and only approved treatment for children and adolescents aged 6-17 years old with fibrosing interstitial lung disease, representing an important step forward for these patients," Deterding said. (pulmonaryfibrosisnews.com)
  • The Scottish Medicines Consortium (SMC) has today announced that Ofev ® (nintedanib) has been accepted for use by NHSScotland for the treatment of adult patients with chronic fibrosing interstitial lung diseases with a progressive phenotype (PF-ILD). (scottishpharmacist.co.uk)
  • Dr Owen Dempsey, Consultant Respiratory Physician, Aberdeen Royal Infirmary said: "The SMC's positive announcement regarding nintedanib means that we will soon have available the first licensed treatment for people living with chronic fibrosing interstitial lung diseases with a progressive phenotype. (scottishpharmacist.co.uk)
  • The natural history of progressive fibrosing interstitial lung diseases. (scottishpharmacist.co.uk)
  • 2018 Presentation, diagnosis and clinical course of the spectrum of progressive-fibrosing interstitial lung diseases. (scottishpharmacist.co.uk)
  • 2020. Progression of fibrosing interstitial lung disease. (scottishpharmacist.co.uk)
Nephrogenic fibrosing6
  • Nephrogenic fibrosing dermopathy (NFD) causes thickening and hardening of the skin, often in the extremities, and occurs in patients with underlying renal disease. (cdc.gov)
  • Osseous metaplasia in the setting of nephrogenic fibrosing dermopathy. (qxmd.com)
  • Nephrogenic fibrosing dermopathy (NFD) is a new skin-fibrosing disorder associated with renal dysfunction. (qxmd.com)
  • Nephrogenic Fibrosing Dermopathy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (sdsu.edu)
  • This graph shows the total number of publications written about "Nephrogenic Fibrosing Dermopathy" by people in this website by year, and whether "Nephrogenic Fibrosing Dermopathy" was a major or minor topic of these publications. (sdsu.edu)
  • Below are the most recent publications written about "Nephrogenic Fibrosing Dermopathy" by people in Profiles. (sdsu.edu)
Chronic4
  • Whereas almost all patients with idiopathic pulmonary fibrosis (IPF) progress, a variable proportion of patients with other common ILDs, including connective tissue disease associated ILD, chronic hypersensitivity pneumonitis, and unclassifiable ILD, develop progressive fibrosing ILD. (nih.gov)
  • The PF-ILD Proteomics study was a targeted investigation of inflammation-related proteins to identify and validate novel biomarkers of progressive fibrosing ILD in patients with fibrotic connective tissue disease-associated ILD, chronic hypersensitivity pneumonitis, and unclassifiable ILD. (nih.gov)
  • This is among the first claims-based estimates of the prevalence of non-IPF chronic fibrosing ILD with a progressive phenotype . (bvsalud.org)
  • As a leader in medical research, Boehringer Ingelheim is committed to transforming fibrosing lung diseases from fatal diseases to chronic, treatable ones. (businesswire.com)
Phenotype2
  • Patients likely to have non-IPF fibrosing ILD with a progressive phenotype were identified via an algorithm that incorporated ILD-related diagnosis codes (excluding IPF) and claims-based proxies for fibrotic ILD progression, including pulmonary function tests , chest imaging, oral corticosteroid (OCS) medications, immunosuppressive medications, lung transplant , oxygen therapy, palliative care, and respiratory hospitalization . (bvsalud.org)
  • [iii] On average,13-40% of patients with ILD might develop a progressive fibrosing phenotype. (scottishpharmacist.co.uk)
Aged 6-17 years1
  • Methods Patients aged 6-17 years with fibrosing ILD on high-resolution computed tomography and clinically significant disease were randomised 2:1 to receive nintedanib or placebo for 24 weeks and then open-label nintedanib. (ersjournals.com)
Nintedanib2
  • The primary objectives of the InPedILD trial were to determine the dose-exposure and safety of nintedanib in children and adolescents with fibrosing ILD. (ersjournals.com)
  • Conclusions In children and adolescents with fibrosing ILD, a weight-based dosing regimen resulted in exposure to nintedanib similar to adults and an acceptable safety profile. (ersjournals.com)
ILDs4
  • Several blood-based biomarkers have been linked to differential progression in patients with IPF and other fibrosing ILDs. (nih.gov)
  • If approved, Ofev would become the first and only therapy available to treat children with fibrosing ILDs, according to its manufacturer Boehringer Ingelheim . (pulmonaryfibrosisnews.com)
  • The therapy is currently approved for managing several lung disorders in adults, including idiopathic pulmonary fibrosis , scleroderma-associated ILD , and progressive fibrosing ILDs . (pulmonaryfibrosisnews.com)
  • The study enrolled 39 children with fibrosing ILDs who were treated with Ofev or a placebo for about half a year. (pulmonaryfibrosisnews.com)
Patients4
  • The files of all consecutive adult patients with fibrosing ILD (2010-2017) were examined retrospectively for pre-defined criteria of ≥10% fibrosis on high-resolution computed tomography and progressive disease during overlapping windows of 2 years. (nih.gov)
  • Fibrosing colonopathy is associated with high-dose use of pancreatic enzyme replacement in the treatment of cystic fibrosis patients. (nih.gov)
  • Patients who died of any cause, underwent lung transplant, or experienced 10% or greater relative FVC decline within 12 months of blood draw were deemed to have progressive fibrosing ILD. (nih.gov)
  • Of nearly 9 million study-eligible patients , 17,136 were identified with non-IPF fibrosing ILD. (bvsalud.org)
Cryptogenic2
  • We have previously suggested that cryptogenic fibrosing alveolitis (CFA) may be caused by occupational exposures, particularly to metal or wood dust. (nih.gov)
  • In the past, idiopathic pulmonary fibrosis (IPF) was used in the USA and cryptogenic fibrosing alveolitis was used in the UK, and both referred to a collection of entities that included a range of histological patterns. (bmj.com)
Progressive1
  • As such, cytokines, interleukins, and other immune mediators might serve as useful biomarkers of progressive fibrosing ILD. (nih.gov)
Inflammatory2
  • Histologically, the lesions were characterized by an inflammatory fibrosing process that showed three distinctive histologic patterns. (nih.gov)
  • We have referred to this condition, both in our consultation reports and in the third series of A.F.I.P. Fascicle on Tumors of the Thyroid Gland, as "multifocal fibrosing thyroiditis" or (less frequently) "multifocal sclerosing thyroiditis," which are descriptive terms that highlight the benign/inflammatory nature of the process, its multiplicity, and its unknown pathogenesis. (ipathology.cn)
Tissue1
  • A longitudinal study of whole body, tissue, and cellular physiology in a mouse model of fibrosing NASH with high fidelity to the human condition. (uchicago.edu)
Years1
  • Relapse of fibrosing alveolitis (desquamative interstitial pneumonia) after twelve years. (bmj.com)
Conditions1
  • Both talc and asbestos produce various fibrosing conditions. (cdc.gov)
Cases2
  • Multifocal fibrosing thyroiditis: report of 55 cases of a poorly recognized entity. (ipathology.cn)
  • With this purpose, the consultation files of one of the authors (J.R.) were searched for cases coded as multifocal fibrosing thyroiditis or multifocal sclerosing thyroiditis in a 20-year period ranging from January 1989 to December 2009. (ipathology.cn)