Fibronectins. Medical search. Frequent questions

Two types of fibronectin are present in vertebrates: soluble plasma fibronectin (formerly called "cold-insoluble globulin", or CIg) is a major protein component of blood plasma (300 μg/ml) and is produced in the liver by hepatocytes. (wikipedia.org)
One or both of the "extra" type III modules (EIIIA and EIIIB) may be present in cellular fibronectin, but they are never present in plasma fibronectin. (wikipedia.org)
It is present in most cellular fibronectin, but only one of the two subunits in a plasma fibronectin dimer contains a V-region sequence. (wikipedia.org)
Along with fibrin, plasma fibronectin is deposited at the site of injury, forming a blood clot that stops bleeding and protects the underlying tissue. (wikipedia.org)
Fibroblasts secrete proteases, including matrix metalloproteinases, that digest the plasma fibronectin, and then the fibroblasts secrete cellular fibronectin and assemble it into an insoluble matrix. (wikipedia.org)
Fibronectin fragments are obtained from plasma fibronectin by using proteolytic enzymes. (sigmaaldrich.com)
Mosesson MW, Amrani DL, Review : The structure and biological activities of plasma fibronectin. (haemochrom.de)
Miekka SI, Ingham KC, Menache D, Rapid methods for isolation of human plasma fibronectin. (haemochrom.de)
Quitt M, Froom P, Aghai E, Balan E, Hornstein L. Plasma fibronectin levels in patients with coronary artery disease. (haemochrom.de)
Dynamic structure of plasma fibronectin. (haemochrom.de)
Here we demonstrate that Tyr and Trp residues on human plasma fibronectin are highly sensitive to ONOOH with this resulting in the formation of 3-nitrotyrosine, 6-nitrotryptophan and dityrosine as well as protein aggregation and fragmentation. (ku.dk)
Immunofluorescence studies show that plasma fibronectin is bound uniformly over the cell surface of free swimming B. burgdorferi. (johnshopkins.edu)
In addition, the spirochetes are able to bind to plasma fibronectin-coated microwell plates, an interaction that is inhibited by anti-fibronectin antibody as well as exogenous plasma fibronectin. (johnshopkins.edu)

Right here, we examined whether or not function-blocking mAbs directed towards α5β1 can work together with the integrin after it varieties a posh with an RGD-containing fragment of fibronectin. (holliseden.com)
Fibronectin binding sites on cultured human fibroblasts were localized by high voltage electron microscopy using either 5- or 18-nm colloidal gold beads (Au5 or Au18) bound to intact fibronectin, the 70-kD amino-terminal fragment of fibronectin that blocks incorporation of exogenous fibronectin into extracellular matrix, or 160-180-kD fragments of fibronectin with cell adhesion and heparin-binding activities. (rupress.org)
Previous studies have shown that small beads coated with FN7-10, a four-domain cell adhesion fragment of fibronectin, bind to cell surfaces and translocate rearward. (biologists.com)

Fibronectin also binds to other extracellular matrix proteins such as collagen, fibrin, and heparan sulfate proteoglycans (e.g. syndecans). (wikipedia.org)
Fibronectin also contains domains for fibrin-binding (I1-5, I10-12), collagen-binding (I6-9), fibulin-1-binding (III13-14), heparin-binding and syndecan-binding (III12-14). (wikipedia.org)
These fragments are useful tools for mapping regions within the fibronectin molecule, which are responsible for specific binding to collagen and for other biologically relevant functions. (sigmaaldrich.com)
Conversely, both fibronectin and collagen XVIII are increased in scleroderma skin, suggesting their involvement in the pathogenesis of bullous scleroderma. (cdlib.org)

Preincubation of T pallidum with goat or rabbit antibody to fibronectin blocked treponemal attachment to cultured cells and to isolated capillaries and inhibited treponemal virulence. (bmj.com)
Using a monospecific antibody raised to the human placental fibronectin receptor complex, we found that TGF-.beta.1 stimulated fibronectin receptor synthesis up to 20-40-fold and increase mRNA levels encoding both the .alpha. (eurekamag.com)
Cross-reactivity between the anti-VWF antibody and fibronectin was inhibited by pretreating the antibody with fibronectin-coated plates. (holliseden.com)
So as to generate an antibody directed enzyme prodrug remedy, right here we designed a chimeric protein by fusing the F8 antibody that acknowledges the EDA of fibronectin (expressed on the tumor neovasculature) and an developed variant of the ROS-generating enzyme D-amino acid oxidase (DAAO). (holliseden.com)
Management of fibrotic adjustments by means of the synergistic results of anti- fibronectin antibody and an RGDS-tagged type of the identical antibody . (holliseden.com)
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Pig Fibronectin (FN) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids. (hiv-pharmacogenomics.org)
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Pig Fibronectin (FN) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species. (hiv-pharmacogenomics.org)
Anti-Fibronectin (FN1 or FN) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from human and rodent tissues. (bicellscientific.com)

After deepithelialization, the graft was placed with a fibrin-fibronectin system at the maximum root coverage level, and the flap coronally advanced and sutured. (hindawi.com)
Aim of this case report was to describe a modified bilaminar technique, with a reduced mesiodistal dimension of the CTG and bonded to the radicular dentin by means of a fibrin-fibronectin system. (hindawi.com)
Knowles LM, Gurski LA, Maranchie JK, Pilch J. Fibronectin Matrix Formation is a Prerequisite for Colonization of Kidney Tumor Cells in Fibrin. (jcancer.org)
Colony formation was significantly more efficient in tumor cells embedded in fibrin compared to matrigel and this effect correlates with the capacity of tumor cells to assemble a fibronectin matrix and generate stress fibers. (jcancer.org)
Inhibition of stress fiber formation with the Rho kinase inhibitor Y-27632, in turn, reduced fibronectin matrix assembly and colony formation in fibrin suggesting that spreading is a critical mechanism for the outgrowth of metastatic kidney tumor cells. (jcancer.org)
Fibronectin, Metastasis, Fibrin. (jcancer.org)
When fibrin is formed, fibronectin adheres to fibrin and is covalently linked by cross-linking by factor XIII. (haemochrom.de)
Corbett SA, Lee L, Wilson CL, Schwarzbauer JE, Covalent cross-linking of fibronectin to Fibrin is required for maximal cell adhesion to a fibronectin-fibrin matrix. (haemochrom.de)

Can the fetal fibronectin test really tell me whether I'm in preterm labor? (babycenter.com)
How does the fetal fibronectin test work? (babycenter.com)
A fetal fibronectin test checks a person's risk of preterm birth by measuring fFN in vaginal fluid. (clevelandclinic.org)
If your pregnancy care provider suspects you're at risk for premature labor , they may use a fetal fibronectin test to check for fetal fibronectin in your vaginal fluid. (clevelandclinic.org)
In most cases, pregnancy care providers do a fetal fibronectin test only if a person shows signs of preterm labor. (clevelandclinic.org)
A fetal fibronectin test happens between 22 and 34 weeks of pregnancy. (clevelandclinic.org)
A few factors may make a fetal fibronectin test less accurate. (clevelandclinic.org)
How is a fetal fibronectin test measured? (clevelandclinic.org)
A fetal fibronectin test can either be positive or negative. (clevelandclinic.org)

Fibronectin is a high-molecular weight (~500-~600 kDa) glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. (wikipedia.org)
Fibronectin-1 is involved in the continual formation of the extracellular matrix, which is an intricate lattice of proteins and other molecules that forms in the spaces between cells. (medlineplus.gov)
While laminin and fibronectin are widely used ECM proteins, the one that your cell needs should be determined by test experiments. (sigmaaldrich.com)
Bonds between fibronectin and fibronectin-binding proteins on Staphylococcus aureus and Lactococcus lactis. (duke.edu)
Bacterial cell-wall-associated fibronectin binding proteins A and B (FnBPA and FnBPB) form bonds with host fibronectin. (duke.edu)
The observed inhibition of fibronectin binding was confirmed by a reduction in the expression of genes encoding two major fibronectin-binding streptococcal surface proteins, Sof and SfbI. (microbiologyresearch.org)
Fibronectin proteins are found in the glomerular basement membrane of the mouse kidney. (bicellscientific.com)

Fibronectin (cold-insoluble globulin) is found in plasma and in the extracellular matrix. (haemochrom.de)
In the cold, fibronectin is co-precipitated with fibrinogen (cold-insoluble globulin). (haemochrom.de)

We beforehand demonstrated that Arg-Gly-Asp (RGD)-containing ligand-mimetic inhibitors of integrins are unable to dissociate pre-formed integrin-fibronectin complexes (IFCs). (holliseden.com)
Constitutive Association of Tie1 and Tie2 with Endothelial Integrins is Functionally Modulated by Angiopoietin-1 and Fibronectin. (musc.edu)

It was our objective to study the role of mechanical stimulation on fibronectin (FN) reorganization and recruitment by exposing fibroblasts to shear fluid flow and equibiaxial stretch. (nature.com)

This technique yielded a population of T pallidum that failed to bind to fibronectin. (bmj.com)
The ability of GAS to bind to fibronectin (Fn), a high molecular weight glycoprotein of the extracellular matrix, has long been known to be essential for the pathogen's evolutionary success and fitness. (lu.se)
A brand new mannequin of the α5β1-fibronectin complicated helps our speculation that the epitopes of mAbs that fail to bind to the ligand-occupied state lie inside, or very near, the integrin-fibronectin interface. (holliseden.com)
As a cell crawls along, integrin heterodimers bind extracellular matrix molecules such as fibronectin and help the cell gain traction. (rupress.org)

There are four fibronectin-binding domains, allowing fibronectin to associate with other fibronectin molecules. (wikipedia.org)
As well as, because the obvious molecular weights of VWF and fibronectin are virtually similar, these molecules have been tough to tell apart by SDS-polyacrylamide gel electrophoresis adopted by immunoblotting. (holliseden.com)
As the pulling force increased, the α 5 β 1 -fibronectin association lasted longer, indicating that the molecules do form catch bonds. (rupress.org)
MPO is released extracellularly by activated leukocytes and binds to extracellular molecules including fibronectin, a major matrix glycoprotein involved in endothelial cell binding. (ku.dk)
Here we present evidence for the presence of fibronectin-binding molecules in Borrelia burgdorferi and several other Borrelia species. (johnshopkins.edu)

The kidneys of people with fibronectin glomerulopathy have large deposits of the protein fibronectin-1 in structures called glomeruli. (medlineplus.gov)
Using fluorescence resonance energy transfer (FRET), we detected major changes in the conformation of a constituent ECM protein , fibronectin (Fn), as cells fabricated a thick three-dimensional (3D) matrix over the course of three days. (rsc.org)
Sublethal concentrations of manuka honey effectively prevented the binding of S. pyogenes to the human tissue protein fibronectin, but did not inhibit binding to fibrinogen. (microbiologyresearch.org)

You might expect that the harder the integrin-fibronectin bond is pulled, the more likely it is to break. (rupress.org)

Localization of cell surface sites involved in fibronectin fibrillogenesis. (rupress.org)
Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization (By similarity). (rcsb.org)

Fluorescent tags allow for the visualization of fibronectin to clarify how this extracellular matrix protein may influence migration and signaling. (jefferson.edu)
Here, the Anticalins N7A, N7E and N9B, which possess exquisite specificity and affinity for oncofetal fibronectin carrying the extra domain B (ED-B), a well-known proangiogenic extracellular matrix protein, were applied for immunohistochemical studies. (cipsm.de)

Taken together, the data suggest that fibronectin binds to the surface of the spirochete. (johnshopkins.edu)

The adhesive or opsonic glycoprotein, fibronectin, is associated with the surface of Treponema pallidum as shown by immunofluorescence. (bmj.com)

Fetal fibronectin acts like an adhesive that helps the amniotic sac stick to the wall of your uterus. (clevelandclinic.org)
We confirmed that TGF-.beta.1 increases the expression of fibronectin, an adhesive glycoprotein expression during embryogenesis and tissue remodeling. (eurekamag.com)
In addition, because fibronectin matrix assembly may assembly may involve the fibronectin cell adhesive receptor complex, increased receptor expression may help drive deposition into matrix. (eurekamag.com)

Description: Quantitativesandwich ELISA kit for measuring Rat Fibronectin, FN in samples from serum, plasma, cell culture supernates, tissue homogenates. (hiv-pharmacogenomics.org)
Description: A sandwich quantitative ELISA assay kit for detection of Rat Fibronectin (FN) in samples from serum, plasma or other biological fluids. (hiv-pharmacogenomics.org)

Each fibronectin subunit has a molecular weight of ~230-~275 kDa and contains three types of modules: type I, II, and III. (wikipedia.org)
On Western blot-like assays, B. burgdorferi and some B. afzelii strains express a major fibronectin-binding protein (Fn-BA) with an approximate molecular mass of 52 kDa. (johnshopkins.edu)
Preliminary evidence suggests that fibronectin (and Fn-BA) may play a role as a molecular bridge between the spirochete and other components of the extracellular matrix. (johnshopkins.edu)

Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. (bicellscientific.com)

These fragments of fibronectin are believed to enhance the binding of α4β1 integrin-expressing cells, allowing them to adhere to and forcefully contract the surrounding matrix. (wikipedia.org)
Exposure of fibronectin to MPO/H 2 O 2 /Cl − is shown to result in damage to the functionally important cell-binding and heparin-binding fragments, gross structural changes to the protein, and altered HCAEC adhesion and activity. (ku.dk)

Fibronectin appears to have a role in treponemal attachment. (bmj.com)
Coating the lenses with fibronectin caused a significant increase in attachment of lens epithelial cells for all three lens types. (arvojournals.org)
Cell attachment was more prominent in the acrylic lenses, but the fibronectin coating negated differences in lens type and caused a significant increase in cell attachment across all groups. (arvojournals.org)
To our knowledge, there have been no reports outlining the in vitro rate of LEC attachment to IOLs after coating them with a commercially available fibronectin preparation. (arvojournals.org)
Endothelial cell attachment was supported within the hollow core of the tube, and seen by S.E.M. In this study the development of the proposed fibronectin material is considered, regarding its potential roles in skin replacement therapy and vascular grafting. (ucl.ac.uk)
Human Fibronectin Solution, Virus Inactivated is used as a media supplement in cell culture primarily to facilitate attachment and cytoplasmic spreading during cell and tissue culture for all types of anchorage dependent cells. (akronbiotech.com)

Dilute fibronectin to the desired concentration. (sigmaaldrich.com)
2. What is the best solvent to dilute fibronectin? (sigmaaldrich.com)
Prepare the JBNT/fibronectin nano-matrix solution as described in the text manuscript, and dilute the JBNT and fibronectin solutions with distilled water to make control solutions. (jove.com)

Findings are discussed in terms of the relevance of interaction between treponemes and fibronectin in the pathogenesis of T pallidum. (bmj.com)

These results demonstrate that TGF-.beta.1 stimulates fibronectin receptor synthesis, extending the diverse stimulatory activities of this polypeptide to matrix receptors. (eurekamag.com)
These domains are necessary for the function: Fibronectin mediates cell adhesion to components of the extracellular matrix via cellular receptors. (haemochrom.de)

Fibronectin content in the tumor correlates with the number of blood vessels and tumor growth in the mouse models. (mpg.de)
These results establish that circulating fibronectin modulates blood vessel formation and tumor growth by modifying the amount of and the response to VEGF. (mpg.de)

A quantitative assay using iodine-125 (125I) showed that T pallidum harvested seven days after infection bound more fibronectin than T pallidum harvested 14 days after infection. (bmj.com)

Add 80 microliters of one-milligram-per-milliliter Janus base nanotubes to 40 microliters of one-milligram-per-milliliter fibronectin, and pipette the mixture gently and slowly several times. (jove.com)
Do not repeatedly pipette to resuspend the fibronectin as this may cause the protein to irreversibly precipitate out of solution. (akronbiotech.com)

The fibronectin protein is produced from a single gene, but alternative splicing of its pre-mRNA leads to the creation of several isoforms. (wikipedia.org)
The same technique was used to study total fibronectin (tFn) in synovial tissues as well as ED-A and ED-B containing fibronectin (Fn) isoforms (A-Fn, B-Fn), generated by alternative splicing of pre-mRNA. (nih.gov)

With longer incubations, Au18-fibronectin complexes were arranged into long fibrillar networks on the cell surface and in the extracellular space. (rupress.org)
The appearance of Au18-fibronectin in these fibrillar networks and disappearance of clusters of Au18-fibronectin suggest that Au18-fibronectin complexes are arranged into matrix at specific regions of the cell surface. (rupress.org)

To demonstrate differences in human lens epithelial cell adhesion to different intraocular lens biomaterials in vitro and to determine whether these differences can be influenced by coating the intraocular lens surface with commercially available fibronectin. (arvojournals.org)
This study has demonstrated an approach to quantifying the capacity of fibronectin cables to align human cells. (ucl.ac.uk)
and Yamada, Kenneth M., "Differences in the Biosynthesis and Localization of the Fibronectin Receptor in Normal and Transformed Cultured Human Cells" (1990). (howard.edu)
Akron Bio's Human Fibronectin Solution, Virus Inactivated is a high quality research-grade material designed to support development efforts in the cell therapy industry. (akronbiotech.com)
Akron's Human Fibronectin Solution, Virus Inactivated is purified from this raw material using a sterilized gelatin resin derived from a pharmaceutical-grade polygeline solution. (akronbiotech.com)
For cGMP Human Fibronectin, click here . (akronbiotech.com)
1. Why use Human Fibronectin Solution, Virus Inactivated? (akronbiotech.com)
3. What are the shipping conditions for Human Fibronectin Solution, Virus Inactivated? (akronbiotech.com)
4. What is the shelf-life for Human Fibronectin Solution, Virus Inactivated? (akronbiotech.com)
5. What is the thawing procedure for Human Fibronectin Solution, Virus Inactivated? (akronbiotech.com)
Fibronectin is a large dimeric glycoprotein present in both human plasma and in basement membranes. (ku.dk)
Human coronary artery endothelial cells showed decreased adherence and cell-spreading on ONOOH-modified fibronectin compared to control, consistent with cellular dysfunction induced by the modified matrix. (ku.dk)
Studies on human atherosclerotic lesions have provided evidence for co-localization of 3-nitrotyrosine and fibronectin. (ku.dk)
Fibronectin is encoded by the FN1 gene in human. (bicellscientific.com)
We hypothesized that MPO binding might influence the modifications induced on fibronectin, when compared to reagent HOCl, with this including alterations to the extent of damage to protein side-chains, modified structural integrity, changes to functional domains, and impact on naïve human coronary artery endothelial cell (HCAEC) adhesion and metabolic activity. (ku.dk)
GPR65 inhibits human trophoblast cell adhesion through upregulation of MYLK and downregulation of fibronectin via cAMP-ERK signaling in a low pH environment. (bvsalud.org)

One of these fibronectin-binding domains, I1-5, is referred to as the "assembly domain", and it is required for the initiation of fibronectin matrix assembly. (wikipedia.org)
The goal of this protocol is to show the assembly of a biomimetic nanomatrix (NM) with Janus base nanotubes (JBNTs) and fibronectin (FN). (jove.com)
Surprisingly, the mechanisms of fibronectin assembly remain largely unknown. (jefferson.edu)
ATX-LPA1 axis contributes to proliferation of chondrocytes by regulating fibronectin assembly leading to proper cartilage formation. (musc.edu)

Fibronectin plays a major role in cell adhesion, growth, migration, and differentiation, and it is important for processes such as wound healing and embryonic development. (wikipedia.org)
Fetal fibronectin (fFN) is a large fetal glycoprotein that promotes cellular adhesion at uterine-placental and decidual-fetal membrane interfaces and is released into cervicovaginal secretions when this extracellular matrix is disrupted, leading to its use as a predictor of preterm delivery. (medscape.com)
Importantly, optimal GPR65 levels are required for maintaining normal adhesion, migration, and invasion, whereas overexpression of GPR65 inhibits these functions by activating the cAMP-ERK signaling pathway, upregulating myosin light chain kinase (MYLK) and MYLK3 expression, and subsequently downregulating fibronectin . (bvsalud.org)

The absence of both FnBPs from the surface of S. aureus removed its ability to form a detectable bond with fibronectin. (duke.edu)

Differences in the Biosynthesis and Localization of the Fibronectin Re" by Steven K. Akiyama, Hannu Larjava et al. (howard.edu)

Interactions of fibronectin with Treponema pallidum. (bmj.com)
Atomic force microscopy was used to evaluate binding interactions between a fibronectin-coated probe and laboratory-derived Staphylococcus aureus that are (i) defective in both FnBPA and FnBPB (fnbA fnbB double mutant, DU5883), (ii) capable of expressing only FnBPA (fnbA fnbB double mutant complemented with pFNBA4), or (iii) capable of expressing only FnBPB (fnbA fnbB double mutant complemented with pFNBB4). (duke.edu)
ONOOH-mediated fibronectin modification and compromised cell-matrix interactions, may contribute to endothelial cell dysfunction, a weakening of the fibrous cap of atherosclerotic lesions, and an increased propensity to rupture. (ku.dk)

Binding sites for Au18-fibronectin on the cell surface were localized to specific regions along the edge of the fibroblast and on retraction fibers. (rupress.org)

This protocol demonstrates how to assemble the nano-matrix from Janus base nanotubes synthesized in my lab, as well as the fibronectin protein. (jove.com)

NHS England and the Department of Health and Social Care (DHSC) have been alerted to a supply disruption of Hologic fetal fibronectin (FFN) cassettes used as a preterm birth marker at point of care. (england.nhs.uk)

Fibronectin glomerulopathy is a kidney disease that usually develops between early and mid-adulthood but can occur at any age. (medlineplus.gov)

The coating concentrations of our fibronectins are suggested in Table 1 . (sigmaaldrich.com)
Differences were observed between stoichiometric, and above-stoichiometric MPO concentrations consistent with an effect of MPO binding to fibronectin. (ku.dk)

insoluble cellular fibronectin is a major component of the extracellular matrix. (wikipedia.org)
Cellular fibronectin is assembled into the extracellular matrix, an insoluble network that separates and supports the organs and tissues of an organism. (wikipedia.org)
During extracellular matrix formation, fibronectin-1 helps individual cells expand (spread) and move (migrate) to cover more space, and it also influences cell shape and maturation (differentiation). (medlineplus.gov)
Even though there is an abundance of fibronectin-1 in the glomeruli, the extracellular matrix that supports the blood vessels is weak because the altered fibronectin-1 cannot assist in the matrix's continual formation. (medlineplus.gov)
These data provide the first evidence that matrix maturation occurs and that aging is associated with increased stretching of fibronectin fibrils, which leads to at least partial unfolding of the secondary structure of individual protein modules. (rsc.org)
Next, prepare fibronectin, JBNT, and Fibronectin/JBNT nano-matrix solutions for lyophilized materials observation according to manuscript directions. (jove.com)
Fibronectin is ubiquitously expressed in the extracellular matrix, and experimental evidence has shown that it modulates blood vessel formation. (mpg.de)
Circulating fibronectin enhances its local production in tumors through a positive feedback loop and increases the amount of vascular endothelial growth factor (VEGF) retained in the matrix. (mpg.de)

This effect is more relevant than that of fibronectin produced by endothelial cells and pericytes, which only exert a small additive effect on vessel maturation. (mpg.de)

Indirect immunofluorescence measured by laser confocal microscopy allows quantitative determination of fibronectin and collagens type I, III and XVIII. (cdlib.org)

Au18-fibronectin complexes at these sites were initially localized in clusters that co-aligned with intracellular microfilament bundles. (rupress.org)
Au18-70-kD fragment complexes initially had a similar distribution to Au18-fibronectin complexes. (rupress.org)

To acquire correct information utilizing anti-VWF antibodies, it's needed to pay attention to the opportunity of cross-reactivity with fibronectin. (holliseden.com)

Anatomy2

Chemicals and Drugs6

Analytical, Diagnostic and Therapeutic Techniques and Equipment1

Phenomena and Processes1

Plasma fibronectin13

Fragment of fibronectin3

Collagen4

Antibody8

Fibrin8

Fetal fibronectin test9

Proteins7

Cold-insolubl2

Integrins2

Fibroblasts1

Bind4

Molecules5

Protein-fibronectin3

Integrin-fibronectin1

Fibrillogenesis2

Extracellular matrix2

Binds1

Opsonic glycoprotein1

Adhesive3

Serum2

Molecular3

Involved in cell adhesion1

Fragments2

Attachment6

Dilute3

Interaction1

Receptors2

Tumor2

Bound1

Pipette2

Isoforms2

Fibrillar2

Human16

Assembly4

Adhesion3

Detectable1

Localization1

Interactions3

Fibers1

Assemble1

Preterm birth1

Kidney1

Concentrations2

Matrix8

Endothelial1

Immunofluorescence1

Complexes2

Antibodies1