Fibroblasts genotoxic stress. Medical search. Frequent questions

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Anatomy27

Fibroblasts Cells, Cultured Cell Line Cell Line, Tumor Skin Micronuclei, Chromosome-Defective HCT116 Cells Cell Nucleus 3T3 Cells Cell Line, Transformed HeLa Cells NIH 3T3 Cells Tumor Cells, Cultured Embryo, Mammalian HEK293 Cells Dermis Keratinocytes Lung Chromatin Epithelial Cells Keloid Cytoplasm Mitochondria Extracellular Matrix Lymphocytes Chick Embryo Synovial Membrane

Organisms4

Mice, Knockout Mice, Inbred C57BL Cricetinae Saccharomyces cerevisiae

Diseases9

Genomic Instability Micronuclei, Chromosome-Defective Cell Transformation, Neoplastic Ataxia Telangiectasia Neoplasms Chromosome Aberrations Keloid Fibrosis Scleroderma, Systemic

Chemicals and Drugs127

Mutagens Tumor Suppressor Protein p53 Ataxia Telangiectasia Mutated Proteins Fibroblast Growth Factor 2 Cell Cycle Proteins Methyl Methanesulfonate Fibroblast Growth Factors Tumor Suppressor Proteins Protein-Serine-Threonine Kinases DNA-Binding Proteins Nuclear Proteins Receptors, Fibroblast Growth Factor CRADD Signaling Adaptor Protein RNA, Messenger Fibroblast Growth Factor 1 Proto-Oncogene Proteins c-mdm2 Doxorubicin Checkpoint Kinase 2 DNA Cyclin-Dependent Kinase Inhibitor p21 Proto-Oncogene Proteins c-abl Receptor, Fibroblast Growth Factor, Type 1 RNA, Small Interfering Transcription Factors Mitomycin Histones Etoposide Receptor, Fibroblast Growth Factor, Type 2 Protein Kinases Hydroxyurea Poly(ADP-ribose) Polymerases Carcinogens Methylnitronitrosoguanidine Poly Adenosine Diphosphate Ribose Intracellular Signaling Peptides and Proteins rhoB GTP-Binding Protein DNA Adducts Collagen cdc25 Phosphatases Caspase 2 Proto-Oncogene Proteins zeta-Crystallins Ubiquitin DNA Repair Enzymes Alkylating Agents Cisplatin Cyclins Antibiotics, Antineoplastic Antimutagenic Agents Receptor, Fibroblast Growth Factor, Type 3 Antineoplastic Agents Carrier Proteins Death Domain Receptor Signaling Adaptor Proteins Apoptosis Regulatory Proteins Sirtuin 1 Replication Protein A Enzyme Inhibitors DNA Primers Mitogen-Activated Protein Kinases Ubiquitin-Protein Ligases Recombinant Proteins Bleomycin SUMO-1 Protein Proteins Recombinant Fusion Proteins Proteasome Endopeptidase Complex Chromatin E2F4 Transcription Factor Proto-Oncogene Proteins c-bcl-2 Saccharomyces cerevisiae Proteins Hydrogen Peroxide Reactive Oxygen Species Fibroblast Growth Factor 10 Caspase 3 Histone Acetyltransferases Serine Benzo(a)pyrene NF-kappa B Fibroblast Growth Factor 7 Multiprotein Complexes Collagen Type I Growth Substances DNA-Activated Protein Kinase Caspases Protein Kinase C-delta Phosphoproteins Adaptor Proteins, Signal Transducing DNA, Complementary Protein Isoforms CDC2 Protein Kinase Camptothecin Trans-Activators bcl-2-Associated X Protein Actins p38 Mitogen-Activated Protein Kinases Carcinogens, Environmental Fibronectins Retinoblastoma Protein Receptor, Fibroblast Growth Factor, Type 4 Mutant Proteins Lysine Proliferating Cell Nuclear Antigen I-kappa B Kinase Platelet-Derived Growth Factor Fibroblast Growth Factor 5 BRCA1 Protein Repressor Proteins Antigens, Nuclear Fibroblast Growth Factor 4 RNA-Binding Proteins bcl-X Protein Chromium Rad51 Recombinase Cyclin-Dependent Kinases Green Fluorescent Proteins Cyclin B Neoplasm Proteins DNA-(Apurinic or Apyrimidinic Site) Lyase Phosphatidylinositol 3-Kinases Ribonucleotide Reductases Transforming Growth Factor beta1 Culture Media, Conditioned 4-Nitroquinoline-1-oxide JNK Mitogen-Activated Protein Kinases Matrix Metalloproteinase 1 Caffeine Endonucleases

Analytical, Diagnostic and Therapeutic Techniques and Equipment22

Mutagenicity Tests Comet Assay Transfection Blotting, Western Models, Biological Reverse Transcriptase Polymerase Chain Reaction Dose-Response Relationship, Radiation Flow Cytometry Immunoblotting Fluorescent Antibody Technique Immunohistochemistry Gene Knockdown Techniques Microscopy, Fluorescence Gene Expression Profiling Carcinogenicity Tests Oligonucleotide Array Sequence Analysis Chromatin Immunoprecipitation Immunoprecipitation Coculture Techniques Cell Culture Techniques Culture Media, Conditioned Mutagenesis, Site-Directed

Phenomena and Processes72

DNA Damage Ultraviolet Rays DNA Repair Apoptosis Radiation, Ionizing Cell Cycle Gamma Rays Phosphorylation Signal Transduction Genomic Instability Cell Survival Gene Expression Regulation Mutation Cell Division Cell Aging Transfection G2 Phase Stress, Physiological DNA Breaks, Double-Stranded Protein Binding Micronuclei, Chromosome-Defective Transcription, Genetic S Phase Base Sequence DNA Replication Cell Proliferation Enzyme Activation Transcriptional Activation Genes, p53 Mitosis Promoter Regions, Genetic Down-Regulation Amino Acid Sequence Time Factors Oxidative Stress Dose-Response Relationship, Drug Ubiquitination DNA Adducts Cell Cycle Checkpoints Gene Expression Sister Chromatid Exchange Active Transport, Cell Nucleus Up-Regulation G1 Phase Phenotype Radiation Tolerance Gene Expression Regulation, Neoplastic Chromosome Aberrations Cell Death Sumoylation Protein Processing, Post-Translational Protein Structure, Tertiary Dose-Response Relationship, Radiation Protein Transport Cell Differentiation RNA Interference Acetylation Chromatin Binding Sites Wound Healing Mutagenesis Gene Deletion Gene Silencing Kinetics Plasmids Genes, Reporter Cell Movement Gene Expression Regulation, Enzymologic Recombination, Genetic Cell Adhesion Protein Biosynthesis Drug Resistance, Neoplasm

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Base Sequence Amino Acid Sequence

Health Care2

Ultraviolet Rays Dose-Response Relationship, Radiation

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science Health Care

Fibroblasts DNA Damage Mutagens Tumor Suppressor Protein p53 Ataxia Telangiectasia Mutated Proteins Cells, Cultured Fibroblast Growth Factor 2 Mutagenicity Tests Cell Cycle Proteins Ultraviolet Rays DNA Repair Methyl Methanesulfonate Apoptosis Cell Line Radiation, Ionizing Fibroblast Growth Factors Tumor Suppressor Proteins Cell Cycle Protein-Serine-Threonine Kinases DNA-Binding Proteins Gamma Rays Comet Assay Phosphorylation Signal Transduction Cell Line, Tumor Nuclear Proteins Receptors, Fibroblast Growth Factor Genomic Instability Cell Survival CRADD Signaling Adaptor Protein Gene Expression Regulation Mutation Skin RNA, Messenger Fibroblast Growth Factor 1 Cell Division Proto-Oncogene Proteins c-mdm2 Cell Aging Transfection Molecular Sequence Data G2 Phase Doxorubicin Checkpoint Kinase 2 DNA Cyclin-Dependent Kinase Inhibitor p21 Stress, Physiological DNA Breaks, Double-Stranded Proto-Oncogene Proteins c-abl Protein Binding Micronuclei, Chromosome-Defective HCT116 Cells Cell Nucleus Transcription, Genetic S Phase Receptor, Fibroblast Growth Factor, Type 1 3T3 Cells Cell Transformation, Neoplastic Cell Line, Transformed Base Sequence RNA, Small Interfering DNA Replication Transcription Factors Cell Proliferation Mice, Knockout Blotting, Western Enzyme Activation Mitomycin HeLa Cells Histones NIH 3T3 Cells Etoposide Receptor, Fibroblast Growth Factor, Type 2 Tumor Cells, Cultured Protein Kinases Transcriptional Activation Genes, p53 Hydroxyurea Mitosis Poly(ADP-ribose) Polymerases Promoter Regions, Genetic Carcinogens Down-Regulation Amino Acid Sequence Time Factors Models, Biological Methylnitronitrosoguanidine Poly Adenosine Diphosphate Ribose Oxidative Stress Ataxia Telangiectasia Intracellular Signaling Peptides and Proteins Dose-Response Relationship, Drug Ubiquitination rhoB GTP-Binding Protein Embryo, Mammalian DNA Adducts Collagen cdc25 Phosphatases Cell Cycle Checkpoints Caspase 2 Gene Expression

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