• We took a comparative approach to studying mossy fiber action potential initiation and propagation in hippocampal slices from juvenile rats. (elsevierpure.com)
  • This paper presents a micromechanics-based 3D finite element model for predicting the damage initiation, propagation, and failure strength of TC33/Epoxy carbon fiber reinforced polymer (CFRP) unidirectional lamina under biaxial loadings. (researchgate.net)
  • The concrete cover controls the migration of chlorides, thereby affecting the initiation and progression of corrosion damage, and the presence of an effective propagation depth is substantiated. (concrete.org)
  • Results indicated that addition of fibers in high-performance concrete (HPC) can effectively restrain the initiation and propagation of cracks under stress, and enhance the impact strengths, toughness and ductility of HPC. (ac.ir)
  • terpenes are a significant factor in the initiation, exacerbation, and propagation of some cases of chemical sensitivity. (cdc.gov)
  • Some inherited arrhythmias are caused by a malfunction of proteins that are related to the initiation or propagation of electrical activity. (medscape.com)
  • Söylev and Özturan concentrated on the mechanical properties of a low-volume fraction (0.5% steel fibers + 0.1% polypropylene, 0.1% glass fiber) FRC [ 6 ]. (hindawi.com)
  • In this experimental investigation, w/cm ratios of 0.4 and 0.3, silica fume replacement at 10% and 15% and crimped steel fibers with an aspect ratio of 80 were used. (ac.ir)
  • Steel fibers were observed to have significant effect on flexural strength of concrete. (ac.ir)
  • This velocity is slower than the conduction velocity of the Schaffer collaterals or mossy fibers. (nih.gov)
  • The Purkinje fiber network is one of the specialized excitation conduction systems that ensure coordinated contraction of the ventricles due to faster excitation conduction than other regions of the heart. (go.jp)
  • In nerve conduction studies, a peripheral nerve is stimulated with electrical shocks at several points along its course to a muscle, and the time to initiation of contraction is recorded. (msdmanuals.com)
  • Thus, conduction velocity is slowed more when larger myelinated fibers are damaged. (msdmanuals.com)
  • In neuropathy, conduction is often slowed, and the response pattern may show a dispersion of action potentials due to unequal involvement of myelinated and unmyelinated nerve fibers. (msdmanuals.com)
  • When a specific neuropathy primarily affects large myelinated fibers, the predominant effect is a decrease in conduction velocity. (msdmanuals.com)
  • However, when neuropathies affect only small umyelinated or thinly myelinated fibers (or when weakness is due to a muscle disorder), the amplitude of action potentials is decreased and nerve conduction velocities are typically normal. (msdmanuals.com)
  • Techniques focusing on single-fiber conduction may be more sensitive for detecting changes associated with neuromuscular junction disorders such as myasthenia gravis. (msdmanuals.com)
  • [ 1 ] The impulse is then conducted through the atrium to the atrioventricular junction from where, after a delay, the electrical signal is propagated to the ventricles along bundles of specialized conduction tissue to the distal Purkinje fibers, which ramify among the contractile myocardium. (medscape.com)
  • Dentate granule neurons give rise to some of the smallest unmyelinated fibers in the mammalian CNS, the hippocampal mossy fibers. (elsevierpure.com)
  • We found that yet unrecognized TRPM4 currents specifically accounted for firing acceleration and that adapting GrCs outperformed accelerating GrCs in transmitting high-frequency mossy fiber (MF) bursts over a background discharge. (nature.com)
  • Aurora offers various functional assays to asses cardiac safety including the action potential of Purkinje fibers as an important site for the initiation of arrhythmias. (aurorabiomed.com)
  • Compared to ventricular muscles, Purkinje fibers may be a better model for studying QT prolongation-related torsade de Pointes (TdP). (aurorabiomed.com)
  • Aurora offers physiologically relevant rabbit whole-ventricle Purkinje fibers preparation for assessment of drug effect on action potential duration. (aurorabiomed.com)
  • However, the relationship between the reduced gap junction conductance and inducibility and sustainability of arrhythmias in the Purkinje fiber network is not clear. (go.jp)
  • The tips of the Purkinje fibers are electrically coupled to muscle cells and the working myocytes are longitudinally connected via gap junctions, thereby initiating a coordinated, efficient contraction of the ventricles. (medscape.com)
  • Surviving axons branch to innervate adjacent muscle fibers, enlarging the motor unit and producing giant muscle action potentials. (msdmanuals.com)
  • Only 60% of the axons in the nerve to a given muscle are motor to the muscle fibers that make up the bulk of the muscle. (medscape.com)
  • The nerve supply branches within the muscle belly, forming a plexus from which groups of axons emerge to supply the muscle fibers. (medscape.com)
  • The axons supply single motor endplates placed about halfway along the muscle fibers. (medscape.com)
  • This paper presents an analytical investigation into the kinetics of chloride and its ensuing potential for diffusion-driven corrosion in a two-span solid-slab highway bridge, including capacity reductions and strength recovery using carbon fiber-reinforced polymer (CFRP) composites. (concrete.org)
  • Four types of FRP composite property parameters, including Carbon Fiber Reinforced Polymer (CFRP), Aramid Fiber Reinforced Polymer (AFRP), Glass Fiber Reinforced Polymer (GFRP), and Basalt Fiber Reinforced Polymer (BFRP), are considered in this research, and a comparative parameter study of FRP unidirectional composite laminates with different off-angle plies using control variate method are discussed. (techscience.com)
  • This nonlinear behavior may develop as the result of cumulative damage processes (for example, matrix cracking, matrix/fiber debonding, fiber fracture, delamination, etc.) which may be influenced by testing mode, testing rate, processing effects, or environmental effects. (astm.org)
  • Our team is interested in the regulation of two time points in cotton fiber development: initiation of fiber growth from ovule epidermal cells and the transition from fiber elongation to secondary wall biogenesis. (usda.gov)
  • 7 ] demonstrated that the compressive strength and drying shrinkage were not promoted by recycled glass fiber reinforced polymer and virgin E-glass fiber additions at a substitution level of 5 wt% of the coarse aggregate, while the splitting tensile strengths were improved in most cases. (hindawi.com)
  • This paper introduces a stiffness reduction based model developed by the authors to characterize accumulative fatigue damage in unidirectional plies and (0/θ/0) composite laminates in fiber reinforced polymer (FRP) composite laminates. (techscience.com)
  • Because narrow rows and frequent plant spacing did not improve lint yield or fiber quality of dryland cotton, we do not recommend this strategy to overcome a thermally limited growing season. (scirp.org)
  • Histologically the mass was composed of numerous plant fibers, with admixed nonfibrous plant material, insect exoskeleton remnants, and rare feather remnants. (vin.com)
  • Neuromuscular junction (NMJ) is the functional contact (synapse) between an axon of motor neuron and muscle fiber. (intechopen.com)
  • It is generally accepted to consider this contact only as a specialized morpho-functional structure, where chemical transmission (via release of the acetylcholine (ACh)) of electrical signal from motor neuron to muscle fiber occurs, ultimately causing the muscle to contract. (intechopen.com)
  • A motor unit comprises a motor neuron in the spinal cord or brainstem together with the squad of muscle fibers it innervates. (medscape.com)
  • Dentate granule neurons exhibited axonal action potential initiation significantly more proximal than CA3 pyramidal neurons. (elsevierpure.com)
  • A sub-study will assess retinal nerve fiber thickness (a marker of axonal loss) by means of optical coherence tomography (OCT). This sub-study will be conducted in selected centers, equipped with this leading edge technology. (salesandmarketingnetwork.com)
  • To identify targetable mechanisms and pathways underlying initiation and progression of SIRD. (lu.se)
  • Diet (e.g. ad libitum): The animals were fed commercial laboratory stock diet ad libitum supplemented by daily lettuce, cabbage, or apples because of their need for dietary fiber. (europa.eu)
  • So, according to numerous studies, not only ACh (which by the way does not always lead to a contraction of the muscle fiber) is released in the vertebrate neuromuscular synapse, but also a number of other synaptically active molecules. (intechopen.com)
  • Muscle fibers can broadly be divided into 3 muscles types: skeletal, cardiac, and smooth muscle. (medscape.com)
  • Likewise, the number of muscle fibers within each of these, as well as the shape of muscles (depending on their function), can also vary greatly. (medscape.com)
  • When the muscles fibers and the associated tendon are arranged along the same axis, the muscle is termed a parallel muscle. (medscape.com)
  • Bipennate muscles have muscles fibers inserting at an angle on both sides of a central tendon. (medscape.com)
  • In large muscles (eg, the flexors of the hip or knee), each motor unit contains 1200 or more muscle fibers. (medscape.com)
  • In small muscles (eg, the intrinsic muscles of the hand), each unit contains 12 or fewer muscle fibers. (medscape.com)
  • A parametric study on crack initiation is done by having different size of cracks at different locations across the layers. (amrita.edu)
  • The proposed damage detection model is developed based on a damage evolution mechanism, including crack initiation and crack damage progress in matrix, matrix-fiber interface and fibers. (techscience.com)
  • Occupational and environmental exposure to respirable fibers and particles potentially causes lung fibrosis that is often progressive and non-curable in humans. (cdc.gov)
  • Criteria for the initiation of ECMO vary by institution, but generally include acute severe cardiac or pulmonary failure that is potentially reversible and unresponsive to conventional management. (wikipedia.org)
  • Notably, the pattern of cells and tissue fibers in the cortex had no influence over these mechanical properties and provided no pre-indication of where the sites of folding would occur. (elifesciences.org)
  • This paper presents experimental studies concerning the effects of fiber content on the mechanical properties and microstructural characteristics of ARGFRC. (hindawi.com)
  • Then the changing law affected by fiber content on these mechanical properties was further analyzed, and the corresponding equation was fitted. (hindawi.com)
  • Ahmad and Zhou discussed the mechanical performances of concrete reinforced with natural or synthetic fibers. (hindawi.com)
  • The recommended fiber content addition by weight was up to 1.0% of the maximum mechanical properties of FRC, while further addition of fibers decreased the mechanical performances due to the lack of workability [ 5 ]. (hindawi.com)
  • However, these fibers are susceptible to shedding due to mechanical wear, and the release of heavy metals from microplastic fibers (MFs) remains largely uncharacterized. (bvsalud.org)
  • A second line of investigation using cotton ovule cultures is focused on determining the signals responsible for switching the fiber away from a growth pattern that causes the fiber to elongate and toward a pathway that stimulates the fiber wall to become thicker. (usda.gov)
  • Each muscle fascicle represents a group of muscle fibers bound together by a layer of connective tissue termed the perimysium. (medscape.com)
  • Akouos is developing targeted adeno-associated viral vector (AAV)-based gene therapies for sensorineural hearing loss, which results from dysfunction or damage to sensory cells and/or nerve fibers of the inner ear. (hearingreview.com)
  • Sensory mediated behavioral effects during exposures to ethyl these nociceptive fibers might trigger neurogenic responses. (cdc.gov)
  • FRC comprises hydraulic cement, aggregates, and discrete reinforcing fibers [ 1 ]. (hindawi.com)
  • These two developmental phases determine key properties of fiber quality and yield. (usda.gov)
  • This approach will identify essential targets for increasing fiber number per seed, an important component of yield. (usda.gov)
  • Our objectives were to quantify planting: 1) row width and 2) in-row spacing effects on growth, yield, and fiber quality of dryland cotton. (scirp.org)
  • These results and computed action current curves agree fairly accurately with published experimental data from frog and toad fibers. (nih.gov)
  • The preliminary experiments reported at this conference are encouraging that this experimental plan is revealing the most important genes in the process of fiber initiation. (usda.gov)
  • An experimental study on the impact performance of silica fume concrete and steel fiber reinforced concrete at 28 days and 56 days under the action of repeated dynamic loading was carried out. (ac.ir)
  • These neurotransmitters diffuse across the synapse and bind to specific receptor sites on the sarcolemma (cell membrane of the muscle fiber). (wikidoc.org)
  • When examined in cross-section, a typical muscle cell reveals between 4 and 6 nuclei, which lie just underneath the plasma membrane of the muscle fiber, the sarcolemma. (medscape.com)
  • Alternative natural fibers can be used not only for textiles, but also for manufacturing composites in place of that made from wood or synthetic materials. (fapesp.br)
  • Deficit appears to be localized in the putamen and globus pallidus resulting in a reduction in the muscle force produced at the initiation of the movement. (wikipedia.org)
  • Amputation-induced proliferation occurred predominantly within the epidermal and intestinal epithelium, as well as wound-adjacent muscle fibers, where clusters of cells at the same stage of the cell cycle were found. (mdpi.com)
  • And these molecules can be released from both nerve terminal (anterograde signal), and from muscle fiber (retrograde signal). (intechopen.com)
  • In mammals and many higher vertebrates, each muscle fiber typically has a single synaptic site innervated by a single motor axon branch. (intechopen.com)
  • Muscle histopathologic findings from a biopsy of the quadriceps showed features of an inflammatory myopathy (interstitial edema, perivascular lymphocytic cuffing, and degenerating fibers) consistent with the features of early dermatomyositis. (cdc.gov)
  • This article mainly focuses on the end organ of this complex interaction, the muscle fiber (myofiber). (medscape.com)
  • What remains constant, however, is that the muscle fibers are aligned in the same direction so that individual muscle fibers can work in concert. (medscape.com)
  • Muscle fibers are long and cylindrical in shape. (medscape.com)
  • Every millimeter of muscle fiber contains approximately 30 nuclei. (medscape.com)
  • These results indicate that CA2 is a unique region which must possess unusual cellular and/or synaptic connectivity properties which result in a decreased threshold for initiation of epileptiform activity. (nih.gov)
  • Diseases that affect the vestibular system such as gait disorders often impair the initiation of a movement. (wikipedia.org)
  • We conclude that while the electrotonically proximal axon location of action potential initiation allows granule neurons to sensitively detect and integrate synaptic inputs, the neurons are sluggish to initiate and propagate an action potential. (elsevierpure.com)
  • Phytohormone regulation of cotton fiber development in vitro. (usda.gov)
  • These events are triggered in vitro by focally applied input, they depend on NMDA current, and they can generate a highly superlinear summation of inputs enabling sets of afferent fibers that terminate in proximity to have much greater impact together than the sum of their separate effects. (jneurosci.org)
  • Age at study initiation: Young adult animals (approx. (europa.eu)
  • Therefore, our study sought to characterize the accumulation of heavy metals on plastic fabrics and the potential for these loaded heavy metals to be released when microplastic fibers originating from these fabrics enter freshwater environments and interact with organisms. (bvsalud.org)
  • A mathematical model of the electrical properties of a myelinated nerve fiber is given, consisting of the Hodgkin-Huxley ordinary differential equations to represent the membrane at the nodes of Ranvier, and a partial differential cable equation to represent the internodes. (nih.gov)
  • Owing to its enhanced strength, ductility, and resistance to harsh environments, increasing research attention has been paid to alkali-resistant glass fiber reinforced concrete (ARGFRC). (hindawi.com)
  • Special glass fiber network with harmonious bending properties. (fischersports.com)
  • It is concluded that the relationship between the drop in stiffness and the number of cycles also shows three different regions, following the mechanism of damage of FRP composites and the matrix is the dominant factor determined by temperature, while fiber strength is the dominant factor that determine the reliability of composite. (techscience.com)
  • On examination with a dissecting microscope, the foreign body was composed of long, fine, frequently split plant fibers admixed with moderate amounts of less fibrous plant material and other debris. (vin.com)
  • A two process model is envisaged: (a) initiation of reactive oxygen species by moderate noise exposure and (b) promotion of oxidative stress through disrupting intrinsic antioxidant defenses. (cdc.gov)
  • As the fiber content increased, the effect of the concrete grout on the fiber packaging decreased, according to the scanning electron microscopy analysis. (hindawi.com)
  • The energy dispersive spectroscopy observation proved that adding a certain fiber content did not affect the concrete hydration reaction. (hindawi.com)
  • There has been a steady increase over the last decades in the use of fiber-reinforced concrete (FRC) in the engineering field. (hindawi.com)
  • 3 ] presented the preparation techniques and the properties of macroplastic fibers, and the effects of macroplastic fibers on the fresh and hardened concrete performances were discussed as well. (hindawi.com)
  • Pulse velocity test was carried out for quality measurements of high-performance steel fiber reinforced concrete. (ac.ir)
  • Flannel Legs Syndrome (FLS): the sensation of walking on cotton or feathers Motor Bradykinesia (slowness of movement) starting from planning to initiation and execution of the movement. (wikipedia.org)
  • When the medium contains the correct nutrients and plant hormones, cotton fibers will develop on the seed surface. (usda.gov)
  • Our team uses this culture system to investigate how cotton fibers begin their growth. (usda.gov)
  • These will be compared with other ones from fibers that present recognized employability in the textile industry. (fapesp.br)
  • The higher the fiber content, the larger the postpeak stiffness of the tested beams. (hindawi.com)
  • Fiber photometry is the process of recording bulk neural activity by measuring fluorescence changes in activity sensitive indicators such as GCaMP through an optical fiber. (nature.com)
  • We systematically studied the effects of pulmonary exposure to MWCNT on the initiation and progress ion of inflammation and fibrosis in mouse lungs. (cdc.gov)
  • After flowering initiation, the action of LFY and AP1 , as well as CAULIFLOWER ( CAL ) results in the upregulation of genes that control floral organ identity [ 20 - 23 ]. (biomedcentral.com)
  • After initiating growth, seed trichomes (fibers) elongate for about 13 days in culture and then begin producing thick, cellulosic secondary cell walls. (usda.gov)
  • Results from a repeat plasma enterovirus PCR 11 days after initiation of IVIg were negative. (cdc.gov)
  • In fiber photometry experiments, excitation light of one or more wavelengths is transmitted to the brain structure of interest through an optic fiber where it excites one or more fluorescent indicators. (nature.com)
  • Consequently, the transition to flowering is under strict genetic and environmental control [ 1 ], with floral initiation being induced by both external (photoperiod- and vernalization-dependent) and internal pathways (autonomous, age- and gibberellin-dependent) [ 2 - 4 ]. (biomedcentral.com)
  • ENVIRONMENTAL IMPLICATION: In recent years, the ecological risks posed by heavy metal contaminants loaded onto microplastic fibers have become an increasing concern. (bvsalud.org)
  • This vector-like behavior underscores the importance of investigating the ecological hazards associated with microplastic fibers carrying contaminants in both environmental and organismal contexts. (bvsalud.org)
  • We present a system of open source hardware and software for fiber photometry data acquisition consisting of a compact, low cost, data acquisition board built around the Micropython microcontroller, and a cross platform graphical user interface (GUI) for controlling acquisition and visualising signals. (nature.com)
  • Turn-key commercial systems exist for fiber photometry data acquisition that are convenient but expensive. (nature.com)
  • and assure the initiation of a research program to fill identified data needs associated with the substances. (cdc.gov)
  • Measured fiber quality occasionally improved with conventional row spacing over ultra-narrow rows, but was unaffected by plant spacing. (scirp.org)
  • I felt this deep, deep warm energy (only way to describe it) spreading through every fiber of my body during the activation! (innermasterytools.com)
  • The eIF2 protein is called an initiation factor because it is involved in starting (initiating) protein synthesis. (medlineplus.gov)
  • For example, they may impair the ability of one of the protein subunits to form a complex with the others, or make it more difficult for the protein to attach to the initiation factor. (medlineplus.gov)
  • the fibers from the phytobezoar were deemed compatible with the leaves of a corn plant. (vin.com)
  • this mass was 2.0 cm in diameter, and examination with a dissecting microscope revealed the same plant fibers as in case 1. (vin.com)