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  • transplant
  • The World Medical Association Declaration of Helsinki and the Declaration on Human Organ Transplantation are followed, as they pertain to the donor and the recipient of the fetal tissue transplant. (wma.net)
  • First ovarian transplant with cryopreserved ovarian tissue was performed by Dr Kutluk Oktay in 1999. (wikipedia.org)
  • http://retractionwatch.wordpress.com/2012/07/26/ovarian-transplant-update-authors-of-2004-live-birth-follow-up-letter-ask-lancet-to-retract-it/ Ralf Dittrich, Laura Lotz, Gudrun Keck, Inge Hoffmann, Andreas Mueller, Matthias W. Beckmann, Hans van der Ven, Markus Montag: Live birth after ovarian tissue autotransplantation following overnight transportation before cryopreservation. (wikipedia.org)
  • A transplant is rejected during first several days or weeks after transplantation. (wikipedia.org)
  • Humans
  • Effects of HIV-1 infection include CD4+ T cell depletion in gut-associated lymphoid tissue (GALT) that closely mimics what is observed in HIV-1-infected humans. (nih.gov)
  • He also pioneered the use of Glial Derived Neurotrophic Factor (GDNF) in combination with fetal cells in humans. (wikipedia.org)
  • A continuing concern is that many animals, such as pigs, have a shorter lifespan than humans, meaning that their tissues age at a quicker rate. (wikipedia.org)
  • 2000
  • Forbes v. Napolitano (2000) was a US court case that established that Arizona researchers could use fetal tissues from induced abortions for basic scientific research, for instance, as a source of stem cells . (asu.edu)
  • aborted fetus
  • Also to avoid conflict of interest, physicians and other health care personnel involved in performing abortions should not receive any direct or indirect benefit from the research or transplantation use of tissues derived from the aborted fetus. (wma.net)
  • experimentation
  • The case challenged the constitutionality of the Arizona Revised Statute (ARS) 36-2303 in the Ninth Circuit US Court of Appeals, a law that banned researchers from using fetal tissues from abortions for any type of medical experimentation or investigation. (asu.edu)
  • The law amended section 32-1854 of the ARS, which classified fetal experimentation as unprofessional conduct. (asu.edu)
  • Furthermore
  • Furthermore, when foetal scalp samples were grafted, the lanugo hairs transformed into terminal hairs along with normal initiation of melanisation. (biomedsearch.com)
  • Furthermore, they argued that fetal tissue was preferred because there was less likelihood that the patient's body would reject the foreign cells. (asu.edu)
  • Furthermore, ovarian tissue is fragile under hard freezing conditions and putting it back into the body carries the risk of re-introducing cancerous cells. (wikipedia.org)
  • procedure
  • Consequently, measures must be taken to assure that decisions to donate fetal tissue for transplantation do not affect either the techniques used to induce the abortion or the timing of the procedure itself with respect to the gestational age of the fetus. (wma.net)
  • graft
  • The ovarian tissue may also be transplanted into mice that are immunocompromised (SCID mice) to avoid graft rejection, and tissue can be harvested later when mature follicles have developed. (wikipedia.org)
  • This type of rejection is very fast, the graft is rejected in a few minutes or hours after the transplantation. (wikipedia.org)
  • Endothelium of the blood vessels is being damaged, therefore the graft is not sufficiently supplied with blood and is replaced with fibrous tissue (fibrosis). (wikipedia.org)
  • retrieval
  • The retrieval and preservation of usable tissue cannot become the primary focus of abortion. (wma.net)
  • There is a potential commercial gain for those involved in the retrieval, storage, testing, preparation, and delivery of fetal tissues. (wma.net)
  • Bardsley says the AGF's fetal-tissue retrieval accounts for 'less than 10 percent of the company's business' and there are strict rules controlling when and under what conditions a technician may perform the procedures. (freerepublic.com)
  • ethical
  • The ethical merits of fetal tissue transplantation have been debated back and forth since 1982, and with temporary government bans only being revoked later on as administrations changed, it may seem that the issue has been a tough nut to crack. (life-kumagaya.com)
  • conduct
  • If your institution is conducting or planning to conduct research involving the transplantation of human fetal tissue for therapeutic purposes, or, if your IRB is reviewing or planning to review such research, your attention to the requirements outlined in the statute is essential. (hhs.gov)
  • research invol
  • In March 1993, NIH published interim guidelines for research involving human fetal tissue transplantation. (hhs.gov)
  • On March 30, 2016, Gu, in his role as CEO of Ganogen, was subpoenaed by the United States House Select Investigative Panel on Planned Parenthood that was created in response to the Planned Parenthood 2015 undercover videos controversy, to testify about his research involving human fetal tissue. (wikipedia.org)
  • grown
  • Lanza and his colleagues were the first to demonstrate that nuclear transplantation could be used to reverse the aging process and to generate immune-compatible tissues, including the first organ grown in the laboratory from cloned cells. (wikipedia.org)
  • ovarian
  • Ovarian tissue cryopreservation is cryopreservation of tissue of the ovary of a female. (wikipedia.org)
  • Cryopreservation of ovarian tissue is of interest to women who want fertility preservation beyond the natural limit, or whose reproductive potential is threatened by cancer therapy, for example in hematologic malignancies or breast cancer. (wikipedia.org)
  • A study of 60 procedures concluded that ovarian tissue harvesting appears to be safe. (wikipedia.org)
  • Strips of cortical ovarian tissue can also be cryopreserved, but it must be re-implanted into the body to allow the encapsulated immature follicles to complete their maturation. (wikipedia.org)
  • In Sep 2004 Prof Donnez of Louvain in Belgium reported the first successful ovarian birth from slow, or controlled rate, frozen ovarian tissue. (wikipedia.org)
  • In 2003, after freeze-thawing, orthotopic autotransplantation of ovarian cortical tissue was done by laparoscopy and five months after reimplantation signs indicated recovery of regular ovulatory cycles. (wikipedia.org)
  • The first birth following transplantation of ovarian tissue, which has been stored at a central cryo bank after overnight transport, has been achieved by centers of the Fertiprotekt network in Germany 2011. (wikipedia.org)
  • This demonstrated that ovarian tissue can be stored centrally in specialized centers. (wikipedia.org)
  • Livebirth after orthotopic transplantation of cryopreserved ovarian tissue The Lancet, Sep 24, 2004 Lan C, Xiao W, Xiao-Hui D, Chun-Yan H, Hong-Ling Y (December 2008). (wikipedia.org)