• Since 2019, the consortium joined the Innovative Medicines Initiative (IMI) funded ConcePTION project, to further research maternal disease and maternal medication exposures during pregnancy and expanding outcomes to include child neuro-developmental outcomes. (ulster.ac.uk)
  • Prof Helen Dolk led Work Package one to initiate the project's research, which focused on investigating how to move beyond pregnancy registries to enhance our understanding of disease-related pregnancy outcomes, medication use and safety of use during pregnancy. (ulster.ac.uk)
  • Maternal fetal stress transfer is a physiological phenomenon in which psychosocial stress experienced by a mother during her pregnancy can be transferred to the fetus. (wikipedia.org)
  • None of the women was in labour and there were no other complications of pregnancy or fetal distress. (portlandpress.com)
  • Conclusion: Teenage pregnancy has adverse impact on the health of teenage mothers leading to various adverse maternal and fetal outcome. (journalcra.com)
  • Conclusion Heart failure during pregnancy is associated with unfavourable fetal outcomes including prematurity and low birth weight. (bmj.com)
  • Studies demonstrate that trauma is more likely to cause maternal death than any other medical complication of pregnancy. (medscape.com)
  • Unless the treating physician is aware of maternal physiologic adaptation to pregnancy, misdiagnosis and suboptimal treatment may ensue. (medscape.com)
  • The risk of fetal congenital heart defect (CHD) gradually increased with increasing pre-pregnancy maternal body mass index (BMI), in a study that used 10-year registry data of all live births, stillbirths, abortions, and terminated pregnancies in Denmark. (medscape.com)
  • There was also no data on family history of CHD, maternal infections, or intake of teratogenic medicine during pregnancy, which have all been associated with a higher risk of CHD. (medscape.com)
  • About one-third (32%) of the women enrolled in the study experienced maternal complications during pregnancy - most commonly, hypertensive (high blood pressure) disorders of pregnancies, or HPD. (lupus.org)
  • Since risk of pregnancy complications and lupus flares partly depends on the population studied, these latest findings add important new insights into maternal and fetal health risks among women with lupus around the world. (lupus.org)
  • Conclusion There was insufficient evidence to ascertain whether maternal exercise in the supine position is safe or should be avoided during pregnancy. (bmj.com)
  • Maternal smoking during pregnancy is an established risk factor for low infant birth weight, but evidence on critical exposure windows and timing of fetal growth restriction is limited. (plos.org)
  • Here we investigate the associations of maternal quitting, reducing, and continuing smoking during pregnancy with longitudinal fetal growth by triangulating evidence from 3 analytical approaches to strengthen causal inference. (plos.org)
  • We analysed data from 8,621 European liveborn singletons in 2 population-based pregnancy cohorts (the Generation R Study, the Netherlands 2002-2006 [ n = 4,682]) and the Born in Bradford study, United Kingdom 2007-2010 [ n = 3,939]) with fetal ultrasound and birth anthropometric measures, parental smoking during pregnancy, and maternal genetic data. (plos.org)
  • The fetal growth trajectory in women who quit smoking in early pregnancy was similar to that of non-smokers, except for a shorter FL and greater AC around 36-40 weeks' gestation. (plos.org)
  • A consistent linear dose-dependent association of maternal smoking with fetal growth was observed from the early second trimester onwards, while no major growth deficit was found in women who quit smoking early in pregnancy except for a shorter FL during late gestation. (plos.org)
  • Maternal smoking during pregnancy is an established risk factor for low infant birth weight. (plos.org)
  • The importance of smoking cessation in early pregnancy and the extent to which fetal growth restriction can be prevented or minimised by lowering cigarette consumption in women who find quitting difficult is also uncertain. (plos.org)
  • We analysed data from 8,621 white European liveborn singletons from 2 population-based pregnancy cohorts to assess the associations of maternal quitting, reducing, and continuing smoking during pregnancy with the longitudinal growth of different fetal parameters (weight, head circumference, femur length, and abdominal circumference). (plos.org)
  • My projects focus on investigating fetal ECG abnormalities in women with Intrahepatic Cholestasis of Pregnancy (ICP) and diabetes, as well as the development of a point-of-care biosensor that can accurately measure serum bile acid concentrations. (kcl.ac.uk)
  • Regional security problems, low access to maternal health services, gender inequality, cultural barriers, inadequate numbers of female health staff, unequipped medical centres, adolescent pregnancy and a high illiteracy rate are factors that may threaten Afghan maternal health (1). (who.int)
  • She enjoys caring for all types of high risk pregnancies, and has particular clinical and research expertise in caring for families who have suffered perinatal trauma due to stillbirth, recurrent early pregnancy loss, and early preterm birth with difficult NICU stays. (ohsu.edu)
  • We measured the height, pre-pregnant body weight, and maternal body weight of women with twin pregnancies and evaluated the relationship between the maternal weight gain at each trimester and fetal growth restriction according to pre-pregnancy body mass index. (researchsquare.com)
  • Especially in normal weight pregnant women, the heavier the weight of the newborn babies as the second trimester of pregnancy weight gain, the less significant the weight gain in the first trimester of pregnancy and fetal growth. (researchsquare.com)
  • In twin pregnancy, regardless of the pre-pregnant body mass index, maternal weight gain affected fetal growth. (researchsquare.com)
  • Furthermore, weight gain in the second trimester of pregnancy is considered a powerful indicator of fetal growth, especially in normal weight pregnancies. (researchsquare.com)
  • Many researchers have suggested criteria for appropriate weight gain during pregnancy based on the maternal pre-pregnancy weight (8, 9). (researchsquare.com)
  • In twin pregnancy, proper maternal weight gain during pregnancy is associated with pregnancy-related complications and neonatal outcomes, as in singleton pregnancy (10-12). (researchsquare.com)
  • If the mother is tall, and the maternal weight gain during pregnancy is appropriate, maternal weight gain can predict fetal growth. (researchsquare.com)
  • The Institute of Medicine and the National Research Council in 1990 and 2009, respectively, presented criteria for adequate weight gain in twin pregnancy (3, 13). (researchsquare.com)
  • However, determining the correlation between maternal weight gain and gestational age of pregnancy was difficult, as it focused on the total weight gain during the entire pregnancy period. (researchsquare.com)
  • Moreover, unlike in singleton pregnancies, twin pregnancy mothers have a higher likelihood of weight gain and pregnancy-related complications, such as fetal growth restriction, preeclampsia, or gestational diabetes (3, 4). (researchsquare.com)
  • This study sought to investigate the relationship between fetal growth and maternal weight gain according to the trimester of twin pregnancy. (researchsquare.com)
  • As we approach the 2-year mark into an unprecedented international pandemic, this review presents the progress and opportunities for research related to COVID-19 and pregnancy. (contemporaryobgyn.net)
  • There are also congenital malformations, maternal complications, and maternal conditions unrelated to pregnancy. (cdc.gov)
  • Perinatal (i.e., the periods of time including pregnancy, childbirth, and infant/child development) and maternal health have been cornerstones of NCTR regulatory science research for over 40 years. (fda.gov)
  • This section includes details of everyone who ever worked with us at the Pregnancy Loss Research Group and their title at the time. (ucc.ie)
  • Fetal Alcohol Spectrum Disorder (FASD) is a diagnostic term that is used to describe the diverse and lifelong developmental effects that exposure to alcohol during pregnancy has on the developing fetus (Cook et al. (aifs.gov.au)
  • It is also conducting research and development work to strengthen norms and standards for newborn health, and is drawing up an integrated strategy to optimize fetal growth and development and improve the outcome of pregnancy. (who.int)
  • Cancer in pregnancy: maternal-fetal conflict. (bvsalud.org)
  • As mortality from other pregnancy conditions, such as hemorrhage and hypertensive disorders, has decreased in developing countries, cardiomyopathy has accounted for an increasing proportion of maternal deaths. (cdc.gov)
  • The longer term goal is to develop a strong PPI network that will facilitate the co-production of research and enhance impact from dissemination of research outcomes (Sinclair, Dolk, Loane and McCullough et al). (ulster.ac.uk)
  • This is a highly innovative global outreach project demonstrating inroads to improved public health outcomes from the implementation of culturally relevant and specifically targeted maternal health education programmes in Myanmar. (ulster.ac.uk)
  • Dr Maria Loane leads the study assessing risk of neurodevelopmental outcomes and congenital anomalies associated with maternal exposure to antidepressants. (ulster.ac.uk)
  • The UK Prevention Research Partnership (UKPRP) - Maternal and Child Health Network (MatchNet) brings together six collaborative UK-based academic institutions, including Ulster, with a view to capitalizing on linked, population-level administrative data and variations in policy across the four nations to assess interventions on and determinants of adverse child outcomes. (ulster.ac.uk)
  • Low Birth Weight 17%, preterm births 23% and NICU admissions 6% were major adverse fetal outcomes. (journalcra.com)
  • HPD is a risk factor independent of lupus disease activity, and it is strongly associated with poor fetal outcomes, particularly stillbirth, prematurity and need for caesarean section. (lupus.org)
  • Overall, more than half (58%) of the pregnancies resulted in poor fetal outcomes. (lupus.org)
  • Fewer than half (46.8%) of the women who conceived while their lupus was in remission experienced poor fetal outcomes, and the researchers found that disease activity during conception was associated with a three-fold increased risk of adverse fetal outcomes. (lupus.org)
  • Is supine exercise associated with adverse maternal and fetal outcomes? (bmj.com)
  • AHRQ Projects funded by the Patient-Centered Outcomes Research Trust Fund. (ahrq.gov)
  • Objectives: To evaluate the controversial benefit of episiotomy by comparing planned episiotomy vs. planned non-episiotomy as regard to maternal and fetal outcomes during spontaneous vaginal delivery. (journalcra.com)
  • Each group was assessed during the early postnatal period for fetal and maternal outcomes and throughout the duration of puerperium for evaluation of maternal morbidities. (journalcra.com)
  • Results: In term pregnancies with spontaneous vaginal deliveries, the episiotomy group had more risk of physical and psychological morbidities than non-episiotomy group, however fetal outcomes were the same in both groups. (journalcra.com)
  • The first phase (quantitative phase) is a prospective study to assess the adolescent pregnant women's health practices and its relationship with maternal, fetal, and neonatal outcomes who live in Tehran, the capital city of Iran. (edu.au)
  • Breakthrough Research Predicts Outcomes for High-Risk. (growingyourbaby.com)
  • The present study examines associations between maternal occupational exposures and ultrasound-measured fetal growth. (cdc.gov)
  • Ventriculomegaly, or dilation of the fetal cerebral ventricles, is a relatively common finding on prenatal ultrasound. (contemporaryobgyn.net)
  • These findings reinforce the importance of smoking cessation advice in preconception and antenatal care and show that smoking reduction can lower the risk of impaired fetal growth in women who struggle to quit. (plos.org)
  • Several new items were added that improve the data file's value for monitoring and research of factors affecting fetal mortality. (cdc.gov)
  • We calculated z-scores from longitudinal growth curves representing trajectories from 0-12, 12-20 and 20-34 gestational weeks for abdominal circumference (AC), biparietal diameter (BPD), femur length (FL), and estimated fetal weight (EFW). (cdc.gov)
  • Associations with trajectories of estimated fetal weight (EFW) and individual fetal parameters (head circumference, femur length [FL], and abdominal circumference [AC]) from 12-16 to 40 weeks' gestation were analysed using multilevel fractional polynomial models. (plos.org)
  • She then continued her medical training by completing a residency in Obstetrics and Gynecology and a fellowship in Maternal Fetal Medicine at UTMB Galveston. (cookchildrens.org)
  • The UCLA Maternal-Fetal Medicine Fellowship is designed to train exceptional clinicians, researchers, and leaders in our field. (uclahealth.org)
  • In accordance with ACGME, our fellowship accommodates the requirements of various research training programs by strictly minimizing the clinical activities to no more than 10% of the fellow's time in the second half (18 months) of training. (uclahealth.org)
  • Primiparous ewes ( n =32) were assigned to dietary treatments in a 2×2 factorial arrangement to determine effects of nutrient restriction and melatonin supplementation on maternal and fetal pancreatic weight, digestive enzyme activity, concentration of insulin-containing clusters and plasma insulin concentrations. (cambridge.org)
  • Nutrient restriction decreased ( P ⩽0.001) maternal pancreatic mass (g) and α -amylase activity (U/g, kU/pancreas, U/kg BW). (cambridge.org)
  • In summary, the maternal pancreas responded to nutrient restriction by decreasing pancreatic weight and activity of digestive enzymes while melatonin supplementation increased α -amylase content. (cambridge.org)
  • OBJECTIVE: To determine if preeclampsia (PE) and intrauterine growth restriction (IUGR) is associated with differing levels of angiogenic and anti-angiogenic growth factors in both maternal and fetal circulation and the effect of heme oxygenase-1 (HO-1) and honokiol, an AKT phosphorylation inhibitor, on endothelial cells (EC) on these anti-angiogenic growth factors. (bham.ac.uk)
  • The cause of maternal death in the emergency department was reviewed in the level I trauma center in Miami, Fla. Motor vehicle collisions was responsible for 72% mortality and penetrating trauma was responsible for a 19% of deaths reported. (medscape.com)
  • Detailed data on Afghan mothers' characteristics, morbidity and mortality from 2017 to 2019 were extracted from the electronic registration system of the Ministry of Health and Medical Education's Maternal Health Office. (who.int)
  • The Afghan mothers' maternal mortality ratio was 43 per 100 000 for these three years. (who.int)
  • According to the WHO report, Maternal mortality: Levels and trends 2000 to 2017, Afghanistan is among the countries with a high (500-999) maternal mortality ratio (MMR). (who.int)
  • Joyce Martin and Donna Hoyert of the Mortality Statistics Branch prepared the Fetal Death Technical Appendix. (cdc.gov)
  • WHO has helped to organize the global conference Tracking progress in child survival: countdown to 2015 (London, 13 and 14 December 2005), the first in a two- year cycle of rolling reviews to assess progress towards reducing child mortality and improving maternal health. (who.int)
  • Cite this: High Maternal BMI Ups Risk of Fetal Congenital Heart Defects - Medscape - Jul 11, 2023. (medscape.com)
  • Maternal occupational exposures and fetal growth in a Spanish birth cohort. (cdc.gov)
  • While the epidemiologic literature suggests certain maternal occupational exposures may be associated with reduced measures of size at birth, the occupational literature employing fetal biometry data to assess fetal growth is sparse. (cdc.gov)
  • Gipuzkoa, Sabadell, Valencia) were used to examine associations between occupational exposures and fetal growth. (cdc.gov)
  • In conclusion, we found limited evidence that maternal occupational exposures impact fetal growth. (cdc.gov)
  • Further research should consider the combined impact of multiple work place exposures. (cdc.gov)
  • We encourage a variety of research exposures during the three years, with former fellows having conducted research in clinical, epidemiology, basic science, and translational research. (uclahealth.org)
  • Responsibilities in this area include performing ultrasounds and formulating plans of care for patients whose pregnancies are complicated by fetal anomalies. (umc.edu)
  • 1. Lipid, apolipoprotein concentration and composition were determined in maternal venous and umbilical arterial and venous blood at delivery by elective Caesarean section in 13 full-term pregnancies and in 25 healthy non-pregnant females. (portlandpress.com)
  • Although the initial focus of management is always maternal stabilization, the approach to treating trauma is different in patients who are pregnant than in patients who are not pregnant. (medscape.com)
  • An understanding of normal maternal-fetal physiology is critical in the diagnosis, surgical management, and postoperative care of pregnant women who require major surgery or who have been injured. (medscape.com)
  • The Society for Maternal-Fetal Medicine supports the clinical practice of maternal-fetal medicine by providing education, promoting research, and engaging in advocacy to optimize the health of high-risk pregnant women and their babies. (contemporaryobgyn.net)
  • View the latest recommendations from the Society for Maternal-Fetal Medicine on anticoagulation in pregnant patients with cardiac disease. (contemporaryobgyn.net)
  • Materials and methods: 200 women with teenage pregnancies (13-19 yrs) were evaluated for maternal risk factors and obstetric outcome. (journalcra.com)
  • Previous studies have reported that maternal obesity is associated with an increased risk of CHD in offspring, but no large studies have included CHD identified prenatally in terminated pregnancies. (medscape.com)
  • Researchers performed a cohort study of all singleton pregnancies in Denmark with estimated due dates between June 1, 2008, and June 1, 2018, using data from the Danish Fetal Medicine database. (medscape.com)
  • Additionally, mothers in the fetal surgery group were at risk for having the surgical scar on the uterus tear or rupture during subsequent pregnancies. (nih.gov)
  • The incidence of twin pregnancies has been increasing due to advanced maternal age and the development of assisted reproductive techniques (ARTs) (1, 2). (researchsquare.com)
  • In our quaternary care, regional transfer center, fellows will learn to care for the highest risk pregnancies from both the maternal and fetal standpoint. (uclahealth.org)
  • Appropriate fetal growth, regulated by maternal nutrition and nutrient transport across the placenta, is a critical factor for adult offspring long-term health. (manchester.ac.uk)
  • Breastfeeding has significant benefits for both maternal and child health. (news-medical.net)
  • An exciting research opportunity has a risen investigating a number of studies in reproductive health. (bmj.com)
  • St George's Healthcare NHS Trust undertakes a range of Reproductive health & Childbirth research trials, and is developing the research portfolio as part of the Fetal health strategy. (bmj.com)
  • It is a research-based independently governed and funded specialised health-focused School with academic departments in Bio, Behavioural, Clinical and Social Science. (bmj.com)
  • Understanding when and which parameters of fetal growth are affected by different smoking behaviours is important for strengthening and focusing clinical and public health guidelines. (plos.org)
  • Background: The health care system of the Islamic Republic of Iran provides special maternal health services for mothers, regardless of their nationality. (who.int)
  • She is a national public health expert for the WHO Framework Convention on Tobacco Control and a member of the recently formed national Growing Up in Ireland Research and Practice Expert Advisory Group. (tcd.ie)
  • She is the current President of the UK and Ireland Society for Social Medicine and Population Health, (the leading society for academic public health research in UK and Ireland), a former External Liaison Officer, and a Senior Mentor for the Society. (tcd.ie)
  • The 1989 revision provides a wide variety of new information on maternal and fetal health characteristics. (cdc.gov)
  • The National Vital Statistics System is an example of intergovernmental sharing of public health data, and in the United States, State laws require the reporting of fetal deaths, and Federal law mandates national collection and publication of the data. (cdc.gov)
  • Nonetheless, the past biennium has witnessed a clear increase in global attention for maternal and child health, including adolescent health. (who.int)
  • The challenge remains to identify delivery strategies that strengthen national health systems' ability to provide efficient, effective, accessible and equitable health services in order to increase coverage of essential maternal, newborn and child health interventions, as envisaged in resolution WHA58.31. (who.int)
  • WHO and concerned partners launched the Partnership for Maternal, Newborn and Child Health in September 2005, to facilitate rapid acceleration of programme implementation through improved partner coordination and coherence. (who.int)
  • Supporting maternal and newborn health. (who.int)
  • She was a recipient of prestigious Training in Dissemination and Implementation Research (TIDIRH) training award at the National Cancer Institute, US in 2016. (tcd.ie)
  • 1] Further research on the uptake survey done in 2016, about half (51%) of the residents were of paediatric TPT is therefore important, including on the current employed and 16% of people were living in informal dwellings. (who.int)
  • Fetal membranes were collected from male preterm infants and chorioamnionitis was diagnosed histologically. (nih.gov)
  • 4. The only significant correlation between maternal and fetal lipoprotein concentrations was in lipoprotein (a) levels ( r = 0.791, P = 0.002). (portlandpress.com)
  • CONCLUSION: This study finds support for fetal origins of endometriosis, in that exposure to adverse environment or restricted development during the perinatal period may increase the risk. (lu.se)
  • Using multidisciplinary approaches, we reveal that maternal exposure to an n-3 PUFA deficient diet impairs offspring's microglial homeostatic signature and phagocytic activity, underpinning excessive synaptic pruning and subsequent behavioral abnormalities. (nature.com)
  • PHCE-funded research falls into the following categories: new alternative models, traditional toxicology studies, translational and clinical studies, computational modeling, bioanalytical chemistry, exposure science, and bioinformatics targeting. (fda.gov)
  • Fetal Alcohol Spectrum Disorder (FASD) is a term used to describe the wide variety of lifelong developmental effects associated with prenatal alcohol exposure. (aifs.gov.au)
  • Non-invasive prenatal diagnosis using fetal cells in maternal blood. (bmj.com)
  • Reviews in this series also include research on multi drug resistance and pre-clinical / clinical findings on novel antibiotics, vaccines, antifungal agents and antitubercular agents. (benthamscience.com)
  • Given the risks that fetal surgery poses for mother and newborn, the findings indicate that, in these cases, it may be better to wait until after birth to perform the corrective spinal surgery. (nih.gov)
  • These findings provide a mechanistic insight into neurodevelopmental defects caused by maternal n-3 PUFAs dietary deficiency. (nature.com)
  • 2. The objectives of the study were to establish whether the placenta has a role in feto-maternal cholesterol metabolism through either synthesis or transplacental cholesterol flux. (portlandpress.com)
  • A review of the medical records of the Cook County Medical Examiner showed that direct and indirect obstetric factors caused maternal deaths in 31.5% of 95 cases. (medscape.com)
  • [ 2 ] Trauma caused maternal deaths in 46.5% of the 95 cases, and, of these traumatic death cases, 34% were due to accidents, 57% to homicide, and 9% to suicide. (medscape.com)
  • The following describes the percentage of traumatic maternal deaths caused by each mechanism of injury in this series. (medscape.com)
  • Fetal deaths for Puerto Rico, Virgin Islands, and Guam are included in a separate data set in the public-use file. (cdc.gov)
  • US Fetal death data are limited to deaths occurring within the United States to U.S. residents and nonresidents. (cdc.gov)
  • Fetal deaths occurring to U.S. citizens outside the United States are not included in this data file. (cdc.gov)
  • Fetal death data for Puerto Rico, Virgin Islands, and Guam are limited to deaths occurring within the respective territories. (cdc.gov)
  • In NCHS tabulations by place of residence, fetal deaths to nonresidents of the United States are excluded. (cdc.gov)
  • In addition, the majority of fetal death tables published by NCHS include only those fetal deaths with stated or presumed gestation of 20 weeks or more (see the Technical Appendix). (cdc.gov)
  • Why focus on fetal deaths of 20 weeks gestation or more in your report - versus fetal deaths of any and all gestation? (cdc.gov)
  • Because the States typically require reporting of these events, we focused on fetal deaths of 20 weeks gestation or more. (cdc.gov)
  • While there are a few states that report fetal deaths at all gestation periods, consistent national data is found at 20 weeks or more. (cdc.gov)
  • At day 17 of gestation, LPD- and Emb-LPD-fed conceptuses displayed smaller placentas and larger fetuses respectively, resulting in increased fetal:placental ratios in both groups compared with NPD conceptuses. (manchester.ac.uk)
  • Therefore, we investigated the effect of maternal (i.e. gestation and lactation) n-3 PUFA deficiency on microglial function and its consequences on hippocampal development. (nature.com)
  • The characteristics of delivery weight and gestation period were different, and for these two, diabetes mellitus emerged, and maternal complications dropped below the top five selected causes for fetuses with longer gestation and heavier delivery weights. (cdc.gov)
  • This year's annual meeting of the Society for Maternal-Fetal Medicine (SMFM) will go down in history as one to remember. (contemporaryobgyn.net)
  • We investigated the associations of maternal and birth characteristics with risk of endometriosis among Swedish women of reproductive age. (lu.se)
  • Questions concerning the Technical Appendix or substantive questions concerning the fetal death or natality data should be directed to the Reproductive Statistics Branch, Division of Vital Statistics, NCHS, 6525 Belcrest Road, Room 840, Hyattsville Maryland 20782. (cdc.gov)
  • In this study, we investigate the impact of maternal nutrition on post-implantation trophoblast phenotype and fetal growth. (manchester.ac.uk)
  • To understand the mechanisms by which n-3/n-6 PUFA imbalance affects CNS development, we investigated the impact of maternal dietary n-3 PUFA deficiency on offspring's microglia, the resident immune cells involved in CNS development and homeostasis 11 . (nature.com)
  • We used a Japanese macaque model to investigate whether maternal obesity combined with a Western-style diet (WSD) impairs offspring muscle insulin action. (diabetesjournals.org)
  • This is a summary of a preprint research study , "Maternal obesity, interpregnancy weight changes and congenital heart defects in the offspring: A nationwide cohort study," by researchers from Copenhagen, Denmark, published on medRxiv and provided to you by Medscape. (medscape.com)
  • According to recent studies, these effects are mainly the result of two particular stress biomarkers circulating in the maternal blood supply: cortisol and catecholamines. (wikipedia.org)
  • During a period of psychosocial stress, cortisol is released, leading to physiological manifestations of stress such as increased maternal blood pressure (MBP) and maternal heart rate (MHR). (wikipedia.org)
  • In cases of very high levels of maternal cortisol, this placental enzyme's expression and activity are greatly reduced, thus buffering the fetus less from the mother's high cortisol levels. (wikipedia.org)
  • Myriad studies in animal models indicate that, if fetal cortisol levels are high, then the HPA axis will be more active postnatally. (wikipedia.org)
  • High levels of fetal cortisol induce higher CRH expression in the paraventricular nucleus of the hypothalamus (PVN) and the central nucleus of the amygdala. (wikipedia.org)
  • This ratio of maternal : foetus cortisol concentration is maintained by an enzyme in the placenta which alters the cortisol molecule into an inactive metabolite (11-keto products), called Placental 11 β-hydroxysteroid-dehydrogenase. (wikipedia.org)
  • The problem lies in the multiplying factor arising from this ratio, i.e., if maternal cortisol levels rise by 10-20% it could cause foetal cortisol levels to double, which is what occurs when the mother experiences psychological distress. (wikipedia.org)
  • The same five causes of fetal death were among the most common selected causes for many maternal characteristics. (cdc.gov)
  • Probably that the variations observed across maternal and fetal characteristics are consistent with those documented in other research. (cdc.gov)
  • The aim of this study was to determine the maternal or fetal origin of inflammatory leukocytes in fetal membranes from cases of chorioamnionitis. (nih.gov)
  • Study limitations include measurement error due to maternal self-report of smoking and the modest sample size for MR analyses resulting in unconfounded estimates being less precise. (plos.org)
  • This study was reviewed by the Duke University Institutional Review Board and declared as exempt research. (cdc.gov)
  • These data demonstrate that early post-implantation embryos modify trophoblast phenotype to regulate fetal growth under conditions of poor maternal nutrition. (manchester.ac.uk)
  • We have previously reported that a maternal dietary n-3 PUFA deficiency alters the microglial phenotype and reduces their motility in the developing hippocampus 17 . (nature.com)
  • The potential for free cholesterol diffusion between mother and fetus and rates of cholesterol esterification and transfer between lipoproteins were determined and related to the differences in composition between fetal and maternal lipoproteins. (portlandpress.com)
  • Objective Theoretical concerns regarding the supine position at rest due to the gravid uterus obstructing aorta and vena caval flow may impinge uterine blood flow (UBF) to the fetus and maternal venous return. (bmj.com)
  • ME Conferences, would like to invite you to attend the International Conference on Fetal and Maternal Medicine scheduled to take place in Istanbul, Turkey on May 30-31, 2019. (aztechcouncil.org)
  • The highest priority during the selection process is given to projects with a potential for wide regulatory impact, including policy changes and realigning industry standards, thereby improving clinical practice and research approaches. (fda.gov)
  • The fellow will also be trained to properly perform fetal echocardiography in addition to multiple perinatal invasive procedures. (umc.edu)
  • The PHCE was established in 2018 as an FDA-wide collaborative effort to review and fund research related to perinatal populations on an annual basis. (fda.gov)
  • We also found that an estimated 26% of the association between maternal smoking and early-onset endometriosis could be explained by birthweight-for-gestational age. (lu.se)
  • The relative concentrations of free cholesterol to phospholipid in maternal and fetal lipoproteins do not indicate the existence of a concentration gradient favouring free cholesterol diffusion across the placenta. (portlandpress.com)
  • Conclusion: Episiotomy is not essential or beneficial in every delivery, so it should not be a routine procedure during delivery and should be individualized according to obstetrician experience and maternal and/or fetal indications. (journalcra.com)