Fecal microbiota transplantation. Medical search. Frequent questions

Fecal microbiota transplantation (FMT) is a therapeutic intervention for inflammatory diseases of the gastrointestinal tract, but its clinical mode of action and subsequent microbiome dynamics remain poorly understood. (nature.com)
Applying an ecology-based framework to our findings indicated parameters that may inform the development of more effective, targeted microbiome therapies in the future, and suggested how patient stratification can be used to enhance donor microbiota colonization or the displacement of recipient microbes in clinical practice. (nature.com)
Fecal microbiota transplantation involves the transfer of gut microbes, viruses and luminal content to modulate a recipient's microbiome, for therapeutic purposes. (nature.com)
Fecal and peripheral blood samples were serially collected to analyze the gut microbiome and exploratory biomarker levels. (news-medical.net)
Fecal microbiota transplantation can reverse the aging of the gut microbiome, at least when carried out in animal studies, and as measured by the detrimental shift in microbial populations that takes place with age. (fightaging.org)
As prevention and management of rCDI has continued to present a challenge, interest has been re-ignited throughout the past decade in the application of a microbiota-based therapeutic for CDI to aid in microbiome restoration. (pharmacytimes.com)
Dysbiosis (also called dysbacteriosis) is characterized by a disruption to the microbiome resulting in an imbalance in the microbiota, changes in their functional composition and metabolic activities, or a shift in their local distribution. (wikipedia.org)
Faecal microbiome of patients in the FMT group showed a reduction in bacteria like Ruminococcus gnavus and enrichment of bacteria such as Lawsonibacter at week 12, while no change in the placebo group. (bvsalud.org)
The findings suggest that newborns at risk for Type 1 diabetes because their microbiome -- the trillions of beneficial microorganisms in and on our bodies -- were disturbed can have the condition reversed by transplanting fecal microbiota from their mother into their gastrointestinal tract after the antibiotic course has been completed. (sciencedaily.com)
The colonic microbiome view is controversial, some people Metagenomics of the Human Intes- is the most diverse and also the best consider the gut microbiota to be tinal Tract (MetaHIT) consortium re- characterized microbial community. (who.int)

1,2 Accumulating evidence suggests that dysbiosis, defined as a perturbation in the intestinal microbiota composition characterized by reduced richness and diversity, is implicated in development of and recovery from CDI. (pharmacytimes.com)
In conclusion, our data provide novel insights into the distinct role of individual commensal bacteria in maintaining immune functions during/following dysbiosis induced by antibiotic therapy thereby shaping host immunity and might thus open novel therapeutical avenues in conditions of perturbed microbiota composition. (uni-kiel.de)
Faecal microbiota transplantation (FMT) is an innovative approach to treat diseases that are associated with gut dysbiosis, by transferring a healthy stool microbiota to a recipient with disease. (ucc.ie)
These findings were accompanied by a significant improvement in the dysbiosis index and comprehensive changes in the fecal bacterial profile. (esanum.com)
Fecal microbiota transplantation consists of introducing a preparation made with stool from a healthy donor into the digestive tract of a recipient with an imbalance of the intestinal microbiota (dysbiosis), in order to restore its microbial biodiversity. (gerpac.eu)
There has been a growing interest in fecal microbiota transplantation (FMT) over recent years, in part due to the increasing prevalence of Clostridium difficile infection (CDI) and expanding association of intestinal dysbiosis with a wide range of human diseases. (johnshopkins.edu)
Any disruption of the body's microbiota is able to lead to dysbiosis. (wikipedia.org)
Fecal Microbiota Transplantation for Dysbiosis - Predictable Risks. (cdc.gov)

In a substudy of STOP-Colitis, response to faecal microbiota transplantation (FMT) in ulcerative colitis (UC) patients was associated with a significant increase in mucosal gut-homing Treg cells and butyrate metabolism, along with a reduction in Th17 cells and multiple anti-microbial and pro-inflammatory pathways [1]. (medicom-publishers.com)

Improved fecal microbiota transplantation, or FMT, can provide better outcomes for patients with recurrent Clostridium difficile infection. (upi.com)
WASHINGTON, Dec. 20 (UPI) -- A new report provides a strategy for improving fecal microbiota transplantation, or FMT, to help doctors better treat patients with recurrent Clostridium difficile infections. (upi.com)
FMT has been successfully used in adults to normalize gut microbiota composition and cure diseases such as recurrent Clostridium difficile infections. (helsinki.fi)
Aim: This Danish national guideline describes the treatment of adult patients with Clostridioides (formerly Clostridium) difficile (CD) infection and the use of faecal microbiota transplantation (FMT). (aau.dk)

Investigating fecal microbial transplant in dogs with inflammatory bowel disease: A pilot study [Abstract]. (uoguelph.ca)

MONDAY, Nov. 20, 2023 (HealthDay News) - For pediatric patients, fecal microbiota transplantation (FMT) is recommended for moderate-to-severe or recurrent Clostridioides difficile infection (CDI), according to a clinical report published online Nov. 20 in Pediatrics . (physiciansweekly.com)
Although antibiotics are the standard-of-care treatment for Clostridioides difficile infection, they can cause further microbiota changes that predispose patients to recurrence. (pharmacytimes.com)
BACKGROUND Fecal microbiota transplantation (FMT) is an effective treatment for recurrent Clostridioides difficile infection (rCDI) in adults and children, but donor stool samples are currently screened for only a limited number of potential pathogens. (jci.org)
Fecal microbiota transplantation (FMT) effectively prevents the recurrence of Clostridioides difficile infection (CDI). (biomedcentral.com)
The recent success gut microbial genes, obtained after has fantastic potential, it has only of faecal microbiota transplantation, sequencing whole faecal microbiota been about 10 years since the sci- especially in the context of Clostridi- metagenomes from 124 European indi- entific community first realized its im- um difficile infection, argues for such viduals [4]. (who.int)

All clinical recommendations were evalluated for evidence level and grade of recommendation.Results: In CD infection, the use of marketed and experimental antibiotics as well as microbiota-based therapies including FMT are described. (aau.dk)

Fecal microbiota transplantation (FMT) has been demonstrated to durably alter the gut microbiota of the recipient and has shown efficacy in the treatment of patients with recurrent CDI. (nih.gov)
In a recent study published in eClinicalMedicine , researchers assess the use of fecal microbiota transplantation to enhance the efficacy of anti-programmed cell death protein 1 (PD-1) therapy for patients with microsatellite stable metastatic colorectal cancer. (news-medical.net)
Based on previous observations that the gut microbiota can improve immune responses, fecal microbiota transplantation has been explored to enhance treatment efficacy by reprogramming the tumor microenvironment in colorectal cancer. (news-medical.net)
The present study was a single-arm, open-label, phase II clinical trial to evaluate the safety and efficacy of combining fecal microbiota transplantation with fruquintinib, which is a small-molecule tyrosine kinase inhibitor of VEGF receptors, and tislelizumab, a monoclonal antibody PD-1 inhibitor. (news-medical.net)
Additional objectives were to compare the efficacy FMT in addition to standard treatment (hypoallergenic diet and immunosuppressive medications) in dogs with IBD versus standard treatment alone in inducing clinical remission, to describe the alteration in the fecal microbiota in dogs undergoing medical therapy for IBD, and to detail a protocol for preparation and administration of FMT in dogs. (uoguelph.ca)
The current follow-up study investigated the efficacy and safety of fecal microbiota transplantation at 1 year after this intervention 1 . (esanum.com)
Fresh fecal transplant and bowel preparation seem also to have impact on FMT efficacy ( p = 0.03 and p = 0.01, respectively). (ibspatient.org)

Although fecal microbiota transplantation (FMT) has been proven as one of the promising treatments for patients with ulcerative colitis (UC), potential prognostic markers regarding the clinical outcomes of FMT remain elusive. (gutnliver.org)
Secondary outcomes were improvement in bloating and change in gut microbiota at week 12. (bvsalud.org)
The study "Systematic review with meta-analysis: review of donor features, procedures and outcomes in 168 clinical studies of faecal microbiota transplantation" comprehensively examines donor characteristics and screening protocols as well as faecal microbiota transplantation procedures and outcomes. (edu.hk)

The transfer of aged donor microbiota into young mice accelerates age-associated central nervous system (CNS) inflammation, retinal inflammation, and cytokine signaling and promotes loss of key functional protein in the eye, effects which are coincident with increased intestinal barrier permeability. (fightaging.org)
Conversely, these detrimental effects can be reversed by the transfer of young donor microbiota. (fightaging.org)
The FMT successfully normalized the patient's gut microbiota, likely by donor microbiota transfer and engraftment. (biomedcentral.com)

Researchers used fecal matter from healthy donors and purified the microbiota from the feces mixing it with saline solution and transplanting it into patients through colonoscopy. (upi.com)
FMT refers to the transplantation of functional bacteria in the feces of healthy donors into the gastrointestinal tract of the patient to restore the balance of the intestinal microecology, which subsequently treats diseases associated with disorders of intestinal microorganisms. (hindawi.com)
Donor: How Do You Select and Screen Candidate Donors for Fecal Microbiota Transplantation? (abdominalkey.com)
Since we have shown that fecal microbiota transplantation (FMT) from lean donors exerts beneficial effects on insulin sensitivity, in the present trial, we investigated the potential synergistic effects on insulin sensitivity of combining a Mediterranean diet with donor FMT in subjects with metabolic syndrome. (asoi.info)

Ulcerative Colitis Disease Activity Index, Crohn's Disease Activity Index, Bath Ankylosing Spondylitis Disease Activity Index - and inflammation biomarkers, including CRP and fecal calprotectin," Dr. Scherl concluded. (medscape.com)

Researchers demonstrated that the intestinal microbiota development can be restored by postnatal, orally-delivered transplantation of maternal fecal microbiota. (helsinki.fi)
During birth by C-section infants are not exposed to maternal fecal microbes and this prevents the natural transfer of microbes from mother to baby. (helsinki.fi)
In the recently reported study, researchers of mainly the University of Helsinki evaluated whether the disturbed intestinal microbiota development could be restored in term Cesarean section infants by postnatal, orally-delivered maternal fecal microbiota transplantation (FMT). (helsinki.fi)
Reference: Korpela K., Helve O., Kolho K-L., Saisto T., Skogberg K., Dikareva E., Stefanovic V., Salonen A., Andersson S., de Vos W. Maternal Fecal Microbiota Transplantation in Cesarean-Born Infants Rapidly Restores Normal Gut Microbial Development: A Proof-of-Concept. (helsinki.fi)
Newborns at risk for Type 1 diabetes because they were given antibiotics may have their gut microorganisms restored with a maternal fecal transplant, according to a new study. (sciencedaily.com)

The human gut contains a diverse ecosystem of microbes: mainly bacteria, as well as viruses and fungi, termed the gut microbiota. (helsinki.fi)
Disturbances of this microbial ecosystem, e.g., by oral exposure to antibiotics, may disrupt the normal function of the microbiota potentially leading to acute expansion of opportunistic pathogenic bacteria [ 2 ]. (biomedcentral.com)
Researchers at Memorial Sloan Kettering Cancer Center have shown that autologous fecal microbiota transplantation (auto-FMT) is a safe and effective way to help replenish beneficial gut bacteria in cancer patients who require intense antibiotics during allogenic hematopoietic stem cell transplantation. (sbbs-soc.com)
Whether FMT from a healthy donor would be as beneficial as the patient's own fecal sample at restoring beneficial bacteria remains to be studied. (sbbs-soc.com)
The gastrointestinal tract is inhabited by trillions of microorganisms, such as bacteria, viruses, and fungi which cooperate with each other to generate a complex organ called gut microbiota. (mdpi.com)
Researchers have shown that autologous fecal microbiota transplantation may be a safe and effective way to help replenish beneficial gut bacteria in patients with cancer who require intense antibiotics during allogeneic hematopoietic stem cell transplantation. (ascopost.com)
Fecal microbiota transplantation, also known as FMT, is a new way to replenish 'good' bacteria in some cancer patients . (medlineplus.gov)
And then if someone has had lots of different treatments but unfortunately get recurrent C. difficile , there's even an option of giving fecal microbiota transplantation to try and replace those good bacteria in the intestine, and almost reset their system. (cdc.gov)

Fecal samples were collected from the feces donor, the mother (before FMT, and 1, 8, 15, 22, 26, and 50 weeks after FMT), and the infant (meconium at birth and 3 and 6 months after birth). (biomedcentral.com)

There is hope that FMT may eventually prove beneficial for the treatment of other diseases associated with alterations in gut microbiota, such as inflammatory bowel disease, irritable bowel syndrome, and metabolic syndrome, to name a few. (nih.gov)
The objectives of this systematic review are to examine the benefits and harms of fecal microbiota transplantation versus placebo or no intervention for the treatment of participants with irritable bowel syndrome. (regionh.dk)
A recently published trial from Norway showed that fecal microbiota transplantation is an effective and safe treatment for patients with irritable bowel syndrome (IBS) after 3 months. (esanum.com)
1. El-Salhy M. Long-term effects of faecal microbiota transplantation (FMT) in patients with irritable bowel syndrome. (esanum.com)
Treatment of Irritable Bowel Syndrome Using Fecal Microbiota Transplantation: A Step Forward? (elsevierpure.com)
Randomised clinical trial: Faecal microbiota transplantation for irritable bowel syndrome with diarrhoea. (bvsalud.org)
Faecal microbiota transplantation (FMT) has been shown to improve symptoms in a proportion of patients with irritable bowel syndrome (IBS). (bvsalud.org)

Altered intestinal microbiota composition in later life is associated with inflammaging , declining tissue function, and increased susceptibility to age-associated chronic diseases, including neurodegenerative dementias . (fightaging.org)

Their gut microbiota composition was monitored for 3 months and compared the composition to that of untreated C-section born infants and vaginally born infants. (helsinki.fi)
Whole metagenomic shotgun sequencing and metabolomics were used to develop a custom analysis workflow, to analyze the changes in gut microbiota composition and metabolic potential. (fightaging.org)
We show that microbiota composition profiles and key species enriched in young or aged mice are successfully transferred by FMT between young and aged mice and that FMT modulates resulting metabolic pathway profiles. (fightaging.org)
Changes in the gut microbiota composition and bacterial strain engraftment after the 2-week dietary regimens and 6 weeks post-FMT were the primary endpoints. (asoi.info)
Altered microbiota composition seems implicated in disease etiology and therefore fecal microbial transplantation (FMT) has emerged as a possible treatment therapy. (ibspatient.org)
discuss an ecological model of pneumonia as a disease "that exists on a continuum of microbiota abundance, diversity, and composition with a range of corresponding immune states. (cdc.gov)

An acute graft-versus-host disease activity index to predict survival after hematopoietic cell transplantation with myeloablative conditioning regimens. (nature.com)
Prospective evaluation for upper gastrointestinal tract acute graft-versus-host disease after hematopoietic stem cell transplantation. (nature.com)
This randomized placebo-controlled double-blind phase II trial tests whether fecal microorganism (microbiota) transplantation prevents severe acute graft versus host disease in adults undergoing allogeneic hematopoietic cell transplantation (HCT). (fredhutch.org)
Establishing a healthy gut microbiota via fecal transplantation may help prevent acute graft versus host disease in patients undergoing allogeneic HCT. (fredhutch.org)

The literature on the microbiota in conditions other than IBD, as well as manipulation of the microbiota through fecal microbial transplant (FMT) on dogs is limited. (uoguelph.ca)
patients were randomized to receive either placebo or fecal microbial transplant (FMT). (uoguelph.ca)
The study compared mice that were exposed to antibiotics between days 5 and 10 of life and given a transplant of maternal microbiota up to a week later, and those that were not. (sciencedaily.com)

This simple procedure can normalize gut microbiota colonization and development in C-section born infants, which will likely contribute to reduced risk of developing chronic diseases that abnormal gut microbiota may confer," adds Dr. Otto Helve MD, specialist in pediatric infectious diseases and shared first author of the study. (helsinki.fi)
Most of the colonization occurs in the first few years of life, but subsequently the microbiota remains relatively stable and distinct to each person into adulthood, even if transient changes occur with diet and medications. (aap.org)

For example, a part of the human microbiota such as the skin flora, gut flora, or vaginal flora, can become deranged, with normally dominating species underrepresented and normally outcompeted or contained species increasing to fill the void. (wikipedia.org)
The human microbiota is com- portance outside the gut, especially a definition [3]. (who.int)

Here we conducted a meta-analysis of novel and published metagenomes from fecal samples collected before and after FMT to compare the fate of donor and recipient strain populations across multiple disease indications. (nature.com)
Fecal microbiota transplantation (FMT) involves the delivery of an entire microbial community from a healthy donor to a recipient with the intention of ameliorating or curing a specific disease. (aap.org)
Allogenic hematopoietic cell transplantation involves a donor - often but not exclusively a family member - who gives the recipient stem cells that re-establish bone marrow production of blood cells and immune function to combat cancer. (sbbs-soc.com)
To define the core transferable microbiota, metagenomic sequencing of donor, recipient, and 4-week post-FMT faecal samples was performed. (medicom-publishers.com)
So, at what point do you seriously consider being a recipient of another person's faecal material, surely one would have to be at deaths door to make that determination? (clinicaleducation.org)

Fecal microbiota transplantation involves receiving processed fecal material orally after allogeneic HCT in order to establish a healthy gut microbiota. (fredhutch.org)

Oral pathogens can affect multiple microbiota compartments of the body and alter systemic processes, such as immunological alterations or digestion issues. (wikipedia.org)
Gut microbiota undergoes major alterations during allogeneic HCT because of antibiotic exposures, nutritional changes, and chemotherapy administration. (fredhutch.org)

Aim of this study was to examine the ability of defined Gram-positive and Gram-negative intestinal commensal bacterial species, namely Escherichia coli and Lactobacillus johnsonii, respectively, to restore immune functions in mice that were immunosuppressed by antibiotics-induced microbiota depletion. (uni-kiel.de)
Even more important are the therapeutic perspectives that will continue to be obtained from the modulation of the microbiota, in particular with antibiotics, probiotics or fecal microbiota transplantation. (mdpi.com)

Among 1462 patients who had allogeneic hematopoietic cell transplantation (HCT) between January 2000 and December 2005, 116 (7.9%) developed stage 3-4 gut GVHD. (nature.com)
Reduced mortality after allogeneic hematopoietic-cell transplantation. (nature.com)

As opposed to what we thought, complete engraftment of microbiota is not required to cure a patient," Sadowsky said. (upi.com)

Additionally, FMT was an easily applicable treatment option in canine IBD which resulted in improved disease severity scores early after therapy whereas placebo treatment did not, although it did not change longer term patient outcome or fecal microbiota diversity in dogs with IBD in this study. (uoguelph.ca)

In another study, Dr Lasha Gogokhia (Weill Cornell Medicine, New York, USA) and colleagues attempted to unravel the mechanisms of clinical response to FMT by identifying a distinct, immune-reactive, core transferable microbiota [2]. (medicom-publishers.com)

For infants as being present in most individuals, body sites and including 151 repre- that are vaginally delivered, the initial but with different relative abundanc- sentative gastrointestinal species gut microbiota resembles the moth- es. (who.int)

Fecal microbiota transplantation (FMT) from healthy individuals to patients with CDI has been used increasingly over the past several decades to restore healthy flora in the gut, thus breaking the cycle of recurrent CDI. (pharmacytimes.com)

After a phase of native microbiota depletion, fecal microbiota transplantation was conducted using orally administered stool capsules that were customized to the patient, along with orally administered fruquintinib and intravenously administered tislelizumab. (news-medical.net)

Fecal Microbiota Transplantation, Commensal Escherichia coli and Lactobacillus johnsonii Strains Differentially Restore Intestinal and Systemic Adaptive Immune Cell Populations Following Broad-spectrum Antibiotic Treatment. (uni-kiel.de)

Individuals with another concomitant cancer, autoimmune disease, a history of immunotherapy or organ transplantation, any factors that would impact the absorption of oral drugs, and those prescribed systemic immunosuppressive therapy were excluded from the study. (news-medical.net)

In the 30 g fecal microbiota transplantation group, 21.6% of patients showed complete remission (IBS-SSS total score of ≤75) after 3 months, which increased to 32.4% at 1 year. (esanum.com)
were significantly lower in the relapsed patients at baseline than in the responders and patients in remission at 1 year after fecal microbiota transplantation. (esanum.com)
The finding that fecal microbiota transplantation induced remission in about half of the patients with IBS emphasizes the role of the intestinal microbiota in the etiology of IBS. (esanum.com)

The combination treatment of fecal microbiota transplantation with tislelizumab and fruquintinib was found to be manageably safe and resulted in improved survival in patients with microsatellite stable metastatic colorectal cancer. (news-medical.net)
It did not resemble that of the untreated C-section born infants, showing that the treatment was effective in restoring normal microbiota development," says Dr. Katri Korpela , first author on the study. (helsinki.fi)
Conventional mice were subjected to broad-spectrum antibiotic treatment for 8 weeks and perorally reassociated with E. coli, L. johnsonii or with a complex murine microbiota by fecal microbiota transplantation (FMT). (uni-kiel.de)
The response to fecal microbiota transplantation was maintained at 1 year after treatment in 86.5% and 87.5% of patients who received 30 g and 60 g fecal microbiota transplantation, respectively. (esanum.com)

Although the anticipated benefit of these commercial microbiota therapeutics is appealing, they will likely come with their own set of challenges for children," the authors write. (physiciansweekly.com)
This review focuses on therapeutics that aim to modulate the gut microbiota and the gut-liver axis. (nih.gov)

could probably be used to predict the outcome of fecal microbiota transplantation. (esanum.com)

The gut microbiota of the patient with CDI differed considerably from the healthy donor and was characterized as low in alpha diversity and enriched for several potential pathogens. (biomedcentral.com)
They used samples from their pilot FMT study in UC patients responsive to a single delivery of high-diversity faecal microbiota preparation [3]. (medicom-publishers.com)
However, no large synergistic effects of combining the diet with lean donor FMT were seen on the gut microbiota diversity after 6 weeks. (asoi.info)

These findings demonstrate that the aging gut microbiota drives detrimental changes in the gut-brain and gut-retina axes suggesting that microbial modulation may be of therapeutic benefit in preventing inflammation-related tissue decline in later life. (fightaging.org)

Each individ- cluding immune cells, but also the was previously cal ed the gastroin- ual harbours hundreds of different metabolic and nervous systems), testinal flora or microflora, the more species, most of which have not and protecting against pathogens pragmatic term "microbiota" is now yet been cultured. (who.int)

Currently, as a means of intestinal microecological regulation in addition to microecological preparations, fecal microbiota transplantation (FMT) has become popular in recent years. (hindawi.com)
Regulatory standards are lacking for fecal preparations for FMT. (physiciansweekly.com)

Recently, fecal microbiota transplantation (FMT) has been defined as the transfer of distal gut microbial communities from a healthy individual to a patient's intestinal tract to cure some immune disorders (mainly inflammatory bowel diseases). (hindawi.com)

Harnessing the gut virome, mycobiome, and bacteriome in combination is a promising prospect for the future of FMT and microbiota-based therapies. (ucc.ie)

The researchers applied FMT immediately after birth by using the infants' own mothers' fecal samples. (helsinki.fi)
DNA extraction from fecal samples and PCR analysis of the 16S gene were subsequently performed, followed by sequencing using an Illumina MiSeq platform. (uoguelph.ca)
Fecal samples were significantly enriched in Faecalibacterium (p=0.047) one week following FMT. (uoguelph.ca)
Fecal samples were profiled by deep metagenomic sequencing for strain-level analysis. (biomedcentral.com)
To define the transferable immune-reactive microbiota (TIM), IgA-sequencing was also performed on these samples. (medicom-publishers.com)
Under healthy conditions, the in- nomes obtained from individuals crobiota resembles the mother's skin testinal microbiota is considered to on three continents, including 760 microbial community, composed of be a stable community, influenced samples from Europe. (who.int)

The community of microorganisms within the human gut (or microbiota) is critical to health and functions with a level of complexity comparable to that of an organ system. (nih.gov)

FDA is informing health care providers and patients of the potential risk of serious or life-threatening infections with the use of fecal microbiota for transplantation (FMT). (fda.gov)
Most IBS patients who responded to fecal transplantation maintained this response after 1 year. (esanum.com)
Changes in the levels of fecal short-chain fatty acids indicated that the microbial metabolism changed from a saccharolytic to a proteolytic fermentation pattern in IBS patients at 1 year after fecal transplantation. (esanum.com)
The study involved cancer patients who provided their own fecal sample, which was frozen and stored prior to their cell transplantation procedure. (sbbs-soc.com)
Persistent nausea and anorexia after marrow transplantation: a prospective study of 78 patients. (nature.com)

Hourigan, SK & Oliva-Hemker, M 2016, ' Fecal microbiota transplantation in children: A brief review ', Pediatric research , vol. 80, no. 1, pp. 2-6. (johnshopkins.edu)

The disruption of "healthy" microbiota promotes the development of several diseases. (mdpi.com)
Gut microbiota plays a role in the pathophysiology of metabolic diseases, which include nonalcoholic fatty liver diseases, through the gut-liver axis. (nih.gov)
Her research interests focus on epidemiological, genetics and microbiota studies of the diseases. (edu.hk)

[2] Marotz CA, Zarrinpar A. Treating Obesity and Metabolic Syndrome with Fecal Microbiota Transplantation. (clinicaleducation.org)

Birth by Cesarean section is detrimental to normal gut microbiota development. (helsinki.fi)
Birth by Cesarean section (C-section) has been shown to be especially detrimental to normal gut microbiota development. (helsinki.fi)

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Analytical, Diagnostic and Therapeutic Techniques and Equipment9

Phenomena and Processes2

Technology, Industry, Agriculture2

Health Care1

Microbiome10

Dysbiosis8

Response to faecal microbiota transplantation1

Clostridium4

Abstract1

Difficile infection5

Infection1

Efficacy7

Outcomes3

Donor microbiota3

Donors4

Ulcerative colitis1

Maternal fecal5

Bacteria8

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Irritable7

Intestinal microbiota composition1

Composition6

Acute graft-versus-4

Transplant3

Colonization2

Human microbiota2

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Antibiotics2

Hematopoietic cell2

Engraftment1

Placebo1

Clinical1

Gastrointestinal1

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Depletion1

Restore1

Organ transplantation1

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Treatment4

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