Features of metabolic syndrome glucose metabolic syndrome is central obesity. Medical search. Frequent questions

This is common in post menopausal women and it can be diagnosed by the presence of following features namely central obesity with waist size greater than 35 inches, Triglyceride levels greater than 150 mg/dL, HDL cholesterol less than 50 mg/dL, Blood glucose in the fasting level 110 mg/dL or more and hypertension greater or equal to 140 / 85. (targetwoman.com)
Abdominal obesity is typically associated with a statistically higher risk of heart disease, hypertension, insulin resistance, and type 2 diabetes (see below). (wikipedia.org)
Previous studies have examined the status of metabolic syndrome with common features like central obesity, hypertension, and glucose intolerance in workers in different occupations, but no study has been conducted on the decontamination workers. (eohp-journal.jp)
4 ) hypertension and, 5 ) impaired fasting glucose (1). (biomedcentral.com)
It is suggested that until the epidemic progression of obesity is stopped and obesity prevented or at least properly managed, cardiologists will be confronted to an evolving contribution of risk factors where smoking, hypercholesterolemia and hypertension may be relatively less prevalent but at the expense of a much greater contribution of abdominal obesity and related features of the metabolic syndrome. (researchgate.net)
This makes it difficult to disentangle independent associations Covid-19 may have with single components of cardiometabolic multimorbidity, defined here as a group of main metabolic disorders that increase the risk of cardiovascular events, such as diabetes, hypertension and dyslipidaemia. (biomedcentral.com)
Like the original UltraMeal medical food powdered drink mix, UltraMeal Bar nutritionally supports the management of conditions associated with metabolic syndrome, such as: -- Central obesity-- Altered body composition -- Hypertension-- Insulin resistance ?A delicious and satisfying formula with a low-glycemic-index (approximately 28) and heart-healthy soy protein that ensures sound nutrition in a convenient, tasty bar form. (proactivwellnesscenters.com)
Many people with metabolic syndrome used to be told they had pre-diabetes, early hypertension (high blood pressure) or mild hyperlipidemia (high fats in the blood). (medlineplus.gov)
Overexpression of 11beta-HSD-1 in mouse adipose tissue leads to a metabolic syndrome-like phenotype including increased central obesity, hypertension, impaired glucose tolerance, and hypertriglyceridemia. (genengnews.com)
Metabolic syndrome is defined as a cluster of metabolic abnormalities including obesity, hyperlipidemia, hyperglycemia, insulin resistance, and hypertension [ 3 ]. (hindawi.com)
In sub-Saharan Africa, hypertension followed by obesity was the commonly known cardiometabolic risk factors associated with the general adult population [ 8 ]. (hindawi.com)
Cardiovascular disease (CVD) risk factors such as obesity, hypertension, and dyslipidaemia are common in patients with DM, placing them at increased risk for cardiac events [ 10 , 11 ]. (hindawi.com)
The metabolic syndrome is a cluster of risk factors that include hypertension, impaired glucose tolerance or diabetes mellitus, central obesity and dyslipidaemia. (biomedcentral.com)
Haglund Garemo also reported that many of the four-year old girls in the study were already displaying signs of the metabolic syndrome, a condition characterized by central obesity, hypertension, and disturbed glucose and insulin metabolism. (rejuvenation-science.com)
filled out a questionnaire referring to major cardiovascular risk factors: smoking, obesity, hypertension, and dyslipidemia. (pharmaceuticalintelligence.com)
the most frequent correlation was found for obesity and hypertension. (pharmaceuticalintelligence.com)
Ce syndrome se caractérise par l'association d'anomalies incluant une résistance à l'insuline, un hyper-insulinisme, une intolérance au glucose ou un diabète de type 2, une hypertension artérielle et des troubles du métabolisme lipidique et de la coagulation. (erudit.org)
It is characterized by a cluster of risk factors of atherosclerosis including insulin resistance, hyperinsulinemia, impaired glucose tolerance or type 2 diabetes, hypertension, dyslipidemia, and coagulation abnormalities. (erudit.org)
Metabolic Syndrome" (MetS), refers to the clustering of abdominal obesity, impaired glucose tolerance, hypertriglyceridemia, diminished high density lipoprotein (HDL) cholesterol, and/or hypertension in an individual. (kauveryhospital.com)
1. Srikanth S, Deedwania P. Management of dyslipidemia in patients with hypertension, diabetes, and metabolic syndrome. (ac.ir)
Metabolic syndrome is a cluster of conditions, which includes elevated blood pressure (hypertension), elevated blood glucose (diabetes), elevated triglycerides and low high-density lipoprotein (HDL) levels (hypercholesterolemia) 1 . (optixanthin.com)
Blood pressure measurement is important, because hypertension is a frequent component of the dysmetabolic syndrome. (medscape.com)
Approximately 40% of individuals with hypertension have impaired glucose tolerance. (medscape.com)
Metabolic Syndrome Metabolic syndrome is characterized by a large waist circumference (due to excess abdominal adipose tissue), hypertension, abnormal fasting plasma glucose or insulin resistance, and dyslipidemia. (msdmanuals.com)
Obesity is associated with hypertension and diabetes, which are risk factors for cardiovascular disease (CVD) (1). (cdc.gov)

Researchers first started to focus on abdominal obesity in the 1980s when they realized it had an important connection to cardiovascular disease, diabetes, and dyslipidemia. (wikipedia.org)
Apart from ovulatory and reproductive dysfunctions, PCOS have chronic metabolic consequences: cardiovascular disease (CVD), obesity, dyslipidemia, obstructive sleep apnoea, and non-fatty liver. (ijpsr.com)
MetS is characterized by central obesity, dyslipidemia, elevated blood pressure, and elevated plasma glucose (Gonçalves et al. (ugr.es)
Metabolic dyslipidemia could lead to non-alcoholic fatty liver disease, and its secondary consequence is the development of metabolic syndrome and diabetes. (ac.ir)

It consists of abnormal serum lipids, glucose intolerance, elevated blood pressure, and central obesity in the setting of insulin resistance. (druglib.com)
WNIN/GR-Ob rats with added glucose intolerance developed retinal degeneration similar to the parent line WNIN/Ob. (molvis.org)
This program addresses several features of the metabolic syndrome, a combination of disorders including abdominal obesity, high blood pressure, and insulin resistance or glucose intolerance, all of which contribute to an increased risk of coronary heart disease, stroke, and type 2 diabetes. (genengnews.com)
The syndromes of insulin resistance actually make up a broad clinical spectrum, which includes obesity, glucose intolerance, diabetes, and the metabolic syndrome, as well as an extreme insulin-resistant state. (medscape.com)
There are varying and similar presentations between patients with type 1 diabetes mellitus, type 2 diabetes mellitus, gestational diabetes, prediabetes, and glucose intolerance. (medscape.com)
Gestational diabetes is typically detected during routine screening of pregnant women for glucose intolerance. (medscape.com)
Any degree of glucose intolerance with onset or recognition during gestation places a patient in the category of gestational diabetes mellitus. (medscape.com)
Diagnosis of glucose intolerance may coincide with various patient conditions that may be complicated by glucose intolerance, such as liver cirrhosis, end-stage renal disease, and some rare genetic disorders. (medscape.com)

Visceral and central abdominal fat and waist circumference show a strong association with type 2 diabetes. (wikipedia.org)
As a consequence, there has also been a marked increase in the prevalence of type 2 diabetes all over the world and this chronic metabolic disease is now considered as a coronary heart disease risk equivalent. (researchgate.net)
ABSTRACT The Arab world is experiencing an epidemic of obesity and type 2 diabetes mellitus. (who.int)
There are alarming data related to the rising prevalence of obesity and type 2 diabetes mellitus in children of Arab ethnicity. (who.int)
Metabolic syndrome is a name for a group of risk factors that occur together and increase the chance of having coronary artery disease , stroke , and type 2 diabetes . (medlineplus.gov)
People with metabolic syndrome have an increased long-term risk of developing heart disease, type 2 diabetes, stroke, kidney disease, and poor blood supply to the legs. (medlineplus.gov)
We hypothesized that a respiratory quotient might predict metabolic syndrome and type 2 diabetes onset. (frontiersin.org)
Two individuals developed type 2 diabetes and 10 metabolic syndrome after 1 year. (frontiersin.org)
Metabolic Syndrome (MetS) and Type 2 diabetes (T2D) are clinical conditions involving the impaired uptake and utilization of glucose, altered lipid metabolism, and the disruption of the metabolic signaling pathways that regulate insulin secretion from pancreas ( 1 ). (frontiersin.org)
failure of the signals or of the B cells to adapt adequately in relation to insulin sensitivity results in inappropriate insulin levels, impaired fasting glucose (IFG), impaired glucose tolerance (IGT), and type 2 diabetes. (medscape.com)
The syndrome has been linked to increased risks of both type 2 diabetes and cardiovascular disease. (rejuvenation-science.com)
Type 2 diabetes mellitus is a common chronic disease which develops insidiously over time, and is associated with obesity, nutritional imbalance (high fructose beverages, high starch and processed foods, carbohydrate excess intake, and an imbalance of proinflammatory to anti-inflammatory polyunsaturated fatty acids), which makes it an acquired and manageable disease. (pharmaceuticalintelligence.com)
4. Legro RS, Kunselman AR, Dodson WC, Dunaif A. Prevalence and predictors of risk for type 2 diabetes mellitus and impaired glucose tolerance in polycystic ovary syndrome: a prospective, controlled study in 254 affected women. (ac.ir)
Whole blood-based transcriptional risk score for nonobese type 2 diabetes predicts dynamic changes in glucose metabolism. (medscape.com)
Metabolic syndrome is a collection of heart diseases causing factors that increase the chance of getting Heart disease, Stroke, and Type 2 Diabetes. (naturalayurvedictreatment.com)

Abdominal obesity, also known as central obesity and truncal obesity, is the human condition of an excessive concentration of visceral fat around the stomach and abdomen to such an extent that it is likely to harm its bearer's health. (wikipedia.org)
Abdominal obesity has been strongly linked to cardiovascular disease, Alzheimer's disease, and other metabolic and vascular diseases. (wikipedia.org)
Abdominal obesity was more closely related with metabolic dysfunctions connected with cardiovascular disease than was general obesity. (wikipedia.org)
Abdominal obesity is linked with higher cardiovascular events among South Asian ethnic population. (wikipedia.org)
Metabolic syndrome is associated with abdominal obesity, blood lipid disorders, inflammation, insulin resistance, full-blown diabetes, and increased risk of developing cardiovascular disease. (wikipedia.org)
Developing asthma due to abdominal obesity is also a main concern. (wikipedia.org)
Obesity causes decreased tidal volumes due to reduced in chest expansion that is caused both by the weight on the chest itself and the effect of abdominal obesity on flattening the diaphragms. (wikipedia.org)
However, even in the absence of the hyperglycaemic state which characterizes type 2 diabetic patients, non diabetic individuals with a specific form of obesity, named abdominal obesity, often show clustering metabolic abnormalities which include high triglyceride levels, increased apolipoprotein B, small dense low density lipoproteins and decreased high density lipoproteins-cholesterol levels, a hyperinsulinemic-insulin resistant state, alterations in coagulation factors as well as an inflammatory profile. (researchgate.net)
This agglomeration of abnormalities has been referred to as the metabolic syndrome which can be identified by the presence of three of the five following variables: abdominal obesity, elevated triglyceride concentrations, low HDL-cholesterol levels, increased blood pressure and elevated fasting glucose. (researchgate.net)
Metabolic syndrome linked to abdominal obesity is also predictive of recurrent coronary events both in post-myocardial infarction patients and among coronary artery disease men who underwent a revascularization procedures. (researchgate.net)
This has led to an increasing evidence for abdominal obesity indices such as waist circumference (WC), waist-to-hip ratio (WHR), and waist-to-height ratio (WHtR) as predictors of CVD [ 16 , 17 ]. (hindawi.com)
The aim of this study was to determine the prevalence of abdominal obesity and its associated factors among adolescents, independent of confounders. (bvsalud.org)
The association of abdominal obesity and independent variables was assessed using the chi-square test and the magnitude of associations was verified using Binary Logistic Regression in an unadjusted model and adjusted for confounders (gender, age, socioeconomic status, physical activity and sedentary behaviour). (bvsalud.org)
The abdominal obesity prevalence was 17.5% (CI = 15.4%-19.6%), and was higher in boys than in girls. (bvsalud.org)
Adolescents with abdominal obesity had higher values of body weight, height, body mass index and sedentary behaviour compared to eutrophic individuals. (bvsalud.org)
Being male increased the risk of abdominal obesity by 36% in adolescents. (bvsalud.org)
Abdominal obesity was significantly associated with gender and high levels of sedentary behaviour, regardless of confounding factors. (bvsalud.org)

The compensatory hyperinsulinemia associates with a set of metabolic features that characterize the metabolic syndrome. (biomedcentral.com)
Erratic lifestyle predisposes to insulin resistance, or obesity leads to subsequent hyperinsulinemia and hyperandrogenemia. (ijpsr.com)
The ovarian androgen excess may be because of an interaction between obesity-related, chronic hyperinsulinemia with genetic factors predisposing to the development of ovarian hyperandrogenism. (scienceopen.com)
Under chronic hyperinsulinemia, FA oxidation progressively decreases with a consequent alteration in glucose transport, and/or phosphorylation pathways associated with normal glucose uptake ( 5 ). (frontiersin.org)
It is now known that Central/Visceral Obesity with its Insulin Resistance and or Hyperinsulinemia is central in the pathogenesis of MetS. (kauveryhospital.com)
Hyperinsulinemia: the key feature of a cardiovascular and metabolic syndrome. (mja.com.au)

Metabolic syndrome (MetS) is associated with several degenerative diseases, including retinal degeneration. (molvis.org)
In this study, we investigated the additional effect of impaired glucose tolerance (IGT), an essential component of MetS, on retinal degeneration using the WNIN/GR-Ob rat model. (molvis.org)
The alarming increase in the prevalence of obesity or MetS is likely to further exacerbate the risk for ophthalmic abnormalities associated with obesity. (molvis.org)
The presence of smaller low-density lipoproteins (LDL) has been associated with atherosclerosis risk, and the insulin resistance (IR) underlying the metabolic syndrome (MetS). (biomedcentral.com)
In addition, some research has supported the association of very low-, low- and high-density lipoprotein (VLDL HDL) particle diameters with components of the metabolic syndrome (MetS), although this has been the focus of less research. (biomedcentral.com)
We aimed to explore the relationship of VLDL, LDL and HDL diameters to MetS and its features, and by clustering individuals by their diameters of VLDL, LDL and HDL particles, to capture information across all three fractions of lipoprotein into a unified phenotype. (biomedcentral.com)
001). However, large VLDL, in the absence of small LDL and HDL particles, did not associate with MetS features. (biomedcentral.com)
While small LDL diameters remain associated with IR and the MetS, the occurrence of these in conjunction with a shift to overall larger VLDL diameter may identify those with the highest fasting glucose, TG and WC within the MetS. (biomedcentral.com)
Our first aim was to report how the diameters correlate across VLDL, LDL and HDL particles and confirm the association between the diameter of each fraction of lipoprotein and features of the MetS. (biomedcentral.com)
This latter step was conducted to ascertain whether any association between MetS features and lipoprotein diameter occurs independently of lipoprotein concentrations, which has been the focus of much previous research. (biomedcentral.com)
Diet-induced obesity in C57BL/6 mice triggers common features of human metabolic syndrome (MetS). (scienceopen.com)
Metabolic syndrome (MetS) is a cluster of interrelated metabolic conditions which increase the risk of developing cardiovascular disease (Kaur, 2014). (ugr.es)
There are limited data on the prevalence rate of Metabolic Syndrome (MetS) among college students attending any Historically Black College and University (HBCU), which are mostly attended by young African Americans (AA). (biomedcentral.com)
According to the NCEP ATP III MetS is defined as the presence of three or more of any of the following criteria in an individual: high waist circumference (WC), elevated fasting glucose (GLU), low high-density lipoprotein cholesterol (HDL-C), elevated triglycerides (TG) and elevated blood pressure (BP)[ 3 ]. (biomedcentral.com)
It is the pathophysiologic aspects of obesity coupled with MetS that leads to changes in hemodynamics, atherosclerosis and calcification, myocardial metabolism, microvascular dysfunction that culminates in myocardial infarction and heart failure. (kauveryhospital.com)
To assess whether a diagnosis of the metabolic syndrome (MetS) improves the prediction of cardiovascular disease or total mortality beyond that already provided by conventional risk factors. (mja.com.au)

Baseline testing includes carotid artery intimal-medial thickness, carotid MRI, lipid panel, complete blood count, comprehensive metabolic chemistry panel, Thyroid-stimulating hormone (TSH) and glucose tolerance test with plasma insulin and glucose responses. (druglib.com)
Abdominal fat is especially active hormonally, secreting a group of hormones called adipokines that may possibly impair glucose tolerance. (wikipedia.org)
In most cases of IGT and impaired fasting glucose, the presence of 1 or more cardiovascular risk factors indicates the need for a screening test for disorders of glucose tolerance. (medscape.com)

Metabolic syndrome is one of the most common disorders in industrialized countries. (druglib.com)
Lysosomal function is critical for organismal homeostasis-mutations in genes encoding lysosomal proteins cause severe human disorders known as lysosomal storage diseases, and lysosome dysfunction is implicated in age-associated diseases including cancer, neurodegeneration and metabolic syndrome. (stanford.edu)
That absorption of gut-derived products is thought to be an initiating factor for obesity and insulin resistance, which are central to all cardiometabolic disorders," said Bruno in a statement. (integrativepractitioner.com)
Alliance targets 11beta-HSD-1 for the treatment of metabolic syndrome disorders. (genengnews.com)
Obesity is also associated with infertility and menstrual irregularities, incontinence, and psychological disorders such as depression. (symptoma.com)
Although asthma and obesity, are two fast growing health problems of public health significance in developing countries, the relationship between these two disorders remains at best shrouded in mystery. (biomedcentral.com)
Acquired or inherited defects associated to environmental factors in any part of this system can lead to metabolic disorders such as the syndrome X which is presently a frequent syndrome in industrialized countries. (erudit.org)
In addition, if necessary, specific treatment of the metabolic disorders is required. (erudit.org)
Rheumatoid Arthritis (RA) is an inflammatory disease associated with high morbidity and increased cardiovascular disease, and Metabolic Syndrome (MS) is understood as a set of metabolic disorders that correlates with obesity and sedentary lifestyle. (scirp.org)
A metabolic syndrome is a group of interrelated common clinical disorders. (naturalayurvedictreatment.com)
The symptoms of metabolic disorders vary widely depending upon the metabolic problem present. (naturalayurvedictreatment.com)

And it is waistline adipose tissue (central obesity) which seems to be the foremost type of fat deposits contributing to rising levels of serum resistin. (wikipedia.org)
ACE significantly reduced the body and peritoneal adipose tissue weights, serum lipid profiles (total cholesterol and triglycerides), glucose levels, hepatic lipid accumulation, and oxidative stress markers. (hindawi.com)
Its pathophysiology is likely to involve insulin resistance at the level of both skeletal muscle and visceral adipose tissue and altered fluxes of metabolic substrates between these tissues that in turn impair liver metabolism. (erudit.org)

Insulin resistance is a major feature of diabetes mellitus type 2, and central obesity is correlated with both insulin resistance and T2DM itself. (wikipedia.org)
Nigeria is a developing country that is currently witnessing an upsurge in diabetes mellitus and obesity with its antecedent consequences. (biomedcentral.com)
New Horizons: Epidemiology of Obesity, Diabetes Mellitus, and Cancer Prognosis. (medscape.com)

Gender-separate receiver operating curve (ROC) analyses were performed for each of the metabolic syndrome components to determine a new population-specific waist circumference cut off. (nwu.ac.za)
Your health care provider who is familiar with metabolic syndrome will make the diagnosis by obtaining the necessary tests, including blood pressure monitoring, waist circumference monitoring, blood glucose, serum insulin, and lipid profile (triglycerides and HDL). (lowcarbneurologist.com)
Increased waist circumference and blood pressures, elevated triglycerides and low High-Density Lipoprotein were the most frequent features of MS. The DAS28 was significantly lower in the reevaluation (p = 0.006). (scirp.org)

The purpose of this study is to examine the effect of long-term treatment with low doses of chloroquine on atherosclerosis in people with metabolic syndrome. (druglib.com)
Published in the journal, Current Developments in Nutrition , the study aimed to determine whether catechin-rich green tea extract could alleviate intestinal inflammation related to cardiometabolic risk in people with metabolic syndrome, a hypothesis established by preclinical evidence. (integrativepractitioner.com)

Polycystic ovarian syndrome, (PCOS) earlier known as the Stein Leventhal syndrome, is a multisystem endocrine disorder with reproductive and metabolic consequences 1 . (ijpsr.com)
Simple measures of gestational weight gain provide insufficient detail of the underlying physiological and metabolic adaptations occurring in pregnancy, and should be complemented by measures of body composition, metabolic and endocrine responses. (karger.com)
Endocrine etiologies for obesity are rare and usually are accompanied by attenuated growth patterns. (medscape.com)
Current opinion in endocrine and metabolic research 2020 9 14 152-159. (cdc.gov)

Polycystic ovarian syndrome (PCOS) is a reproductive metabolic disorder affecting nearly 20% females, globally. (ijpsr.com)
Recommendations From the 2023 International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome. (medscape.com)
Metformin and combined oral contraceptive pills in the management of polycystic ovary syndrome: a systematic review and meta-analysis. (medscape.com)
Polycystic ovary syndrome is a clinical syndrome typically characterized by anovulation or oligo-ovulation, signs of androgen excess (eg, hirsutism, acne), and multiple ovarian cysts in the ovaries. (msdmanuals.com)
Scientific statement on the diagnostic criteria, epidemiology, pathophysiology, and molecular genetics of polycystic ovary syndrome. (msdmanuals.com)
Polycystic ovary syndrome has several significant potential complications. (msdmanuals.com)

Laboratory tests include the plasma glucose level, the fasting insulin level, and a lipid profile, among others. (medscape.com)
Atherogenic lipid profile is a feature characteristic of patients with early rheumatoid arthritis: effect of early treatment-a prospective, controlled study. (ac.ir)

Method: WC, sphygmomanometer blood pressure, fasting bloods (glucose, HDL and triglycerides) and ultrasound carotid intima-media thickness (CIMT) were obtained for 171 black urban teachers from the sympathetic activity and ambulatory blood pressure in Africans (SABPA) study. (nwu.ac.za)
Thus, high blood glucose levels persist, and some of them are converted to triglycerides in the liver, which leads to non-alcoholic fatty liver disease (NAFLD), and with excess triglycerides going to the bloodstream elevating the triglyceride levels in the blood. (lowcarbneurologist.com)

Two-hour postload plasma glucose (2-h PG) and serum insulin and fasting plasma glucose were associated with the third factor. (diabetesjournals.org)
Increased adiposity (obesity) raises serum resistin levels, which in turn directly correlate to insulin resistance. (wikipedia.org)

Obesity and metabolic syndrome (O&MS) due to the worldwide obesity epidemic affects children at all stages of chronic kidney disease (CKD) including dialysis and after kidney transplantation. (springer.com)
We excluded participants with diabetes, metabolic syndrome, chronic diseases, and those who had changed food habits in the previous 3 months. (frontiersin.org)
Obesity Obesity is a chronic, multifactorial, relapsing disorder characterized by excess body weight and defined as a body mass index (BMI) of ≥ 30 kg/m2. (msdmanuals.com)

The characteristic clinical features range from hirsutism, androgenic alopecia 2 , acne, insulin resistance 3 , acanthosis nigricansin 4 , to menstrual dysfunction 5 . (ijpsr.com)
Under the firms' alliance, a small molecule inhibitor of 11beta-hydroxysteroid dehydrogenase (HSD)-1 has advanced into clinical testing as a treatment of diabetes and metabolic syndrome-related diseases. (genengnews.com)
Early clinical evidence has shown that inhibiting 11beta-HSD-1 can reduce glucose and lipids in diabetic patients. (genengnews.com)
In clinical practice, no single laboratory test is used to diagnose insulin resistance syndrome. (medscape.com)
The clinical screenings included measurement of blood pressure and determination of fasting lipid and glucose concentrations. (biomedcentral.com)
However, medical problems associated with the insulin resistance of this syndrome and its corresponding complications may develop over time and themselves present with clinical symptoms. (lowcarbneurologist.com)
Despite the vast clinical experience linking diabetes, obesity and the metabolic syndrome to vascular disease, little is understood regarding the mechansims connecting hyperglycemia to atherosclerosis. (lu.se)
Diabetes is also associated with complications of the microcirculation giving rise to the clinical features of retinopathy, nephropathy and neuropathy. (lu.se)
Central to the development of vascular disease is endothelial dysfunction, which appears well before any clinical sign, but importantly is potentially reversible. (lu.se)
Clinical value of the metabolic syndrome for long term prediction of total and cardiovascular mortality: prospective, population based cohort study. (mja.com.au)
Cushing's syndrome (CS) has a variety of clinical manifestations resulting from excess steroid hormone production from adrenal glands (endogenous) or administration of glucocorticoids (exogenous) [ 1 , 2 ]. (invisionzone.com)
In short, clinical studies revealed that natural astaxanthin helps manage blood glucose levels and lowers risks of diabetes-related complication after 6 to 12 weeks of consumption. (optixanthin.com)
Clinical features of insulin resistance involve skin changes (Acanthosis nigricans). (naturalayurvedictreatment.com)
Other clinical features, such as Kussmaul respiration and altered level of consciousness due to metabolic derangement, are commonly observed during acute deterioration. (medscape.com)
PCOS is usually defined as a clinical syndrome, not by the presence of ovarian cysts. (msdmanuals.com)
To formulate clinical practice guidelines for the assessment, treatment, and prevention of pediatric obesity. (medscape.com)

Central obesity is diagnosed by measuring the waist-hip ratio. (nestle-family.com)
Obesity involved in this is central obesity ( fat over the abdomen and waist). (naturalayurvedictreatment.com)
Abdominal adiposity is a risk factor for obesity-related complications, and there is increasing evidence that abdominal adiposity may be a contributing factor to complications not related to adiposity at the waist (4,5). (cdc.gov)

Gaps exist in our information about diabetes and obesity in Arabpopulations in relation to ethnic-specific cut-off points for diagnosis and treatment of diabetes. (who.int)
We present a 17 year-old woman, with a previous genetic diagnosis of Prader-Willi syndrome and BMI of 74 Kg/m(2), that was admitted in anasarca, with marked cyanosis, dyspnea and oliguria. (symptoma.com)
It is pertinent to note that the presence of obesity creates unique challenges for the diagnosis and treatment of asthma. (biomedcentral.com)
Does a diagnosis of the metabolic syndrome provide additional prediction of cardiovascular disease and total mortality in the elderly? (mja.com.au)

The study was conceived to determine the prevalence of metabolic syndrome among a population of asthmatics seen in our practice. (biomedcentral.com)
The prevalence of metabolic syndrome was 17.7%, affecting 28 asthma patients. (biomedcentral.com)

Obesity and sedentary lifestyle are two common risk factors posed in menopausal women. (targetwoman.com)
Identifying risk factors for erectile dysfunction, including as smoking, obesity, sedentary lifestyle, and persistent alcohol intake, is crucial for preventing erectile dysfunction ( 6 - 8 ). (frontiersin.org)

The syndrome substantially increases the risk of developing diabetes and vascular disease, but there is no clear unifying approach to treat this disorder. (druglib.com)
Metabolic syndrome has become a serious health issue worldwide as the prevalence of obesity increases [ 1 ]. (hindawi.com)
There is growing epidemiological evidence that obesity increases the risk of developing asthma. (biomedcentral.com)
These conditions are normally caused by central obesity and physical inactivity, which further increases the risk of cardiovascular diseases (CVD), particularly heart failure. (optixanthin.com)
The number of cases of metabolic syndrome increases with age. (naturalayurvedictreatment.com)

If replicated, the association of this phenotype with more severe IR-features indicated that it may contribute to identifying of those most at risk for incident type II diabetes and cardiometabolic disease. (biomedcentral.com)
Subjects with T2D, especially those with LDL phenotype B and obesity, have higher levels of inflammatory biomarkers. (biomedcentral.com)
The molecular mechanisms underlying this obesity-induced cardiac phenotype disorder are not well understood. (kauveryhospital.com)

This is especially true of patients who may be at high risk for additional complications, e.g. those with metabolic syndrome, diabetes, or cardiac, cerebrovascular or other neurological diseases. (ersjournals.com)
Weight problems with symptoms of associated complications are the major features of morbid obesity . (symptoma.com)
screening for comorbidities of obesity should be applied in a hierarchal, logical manner for early identification before more serious complications result. (medscape.com)

A genetic predisposition associated to excessive caloric intake and a lack of physical excercise can lead to obesity and central adiposity. (biomedcentral.com)
A patient may have central adiposity in spite of a normal BMI. (medscape.com)

Metabolic syndrome consists of a group of co-occuring conditions that increase an individual's risk of developing heart disease, stroke, and diabetes. (druglib.com)
Regular exercise is essential to combat inactivity and obesity which is a strong risk factor for heart disease. (targetwoman.com)
A waistline of 102 cm or more for men and 88 cm or more for women (measured across the belly) is the form of central obesity most strongly associated with metabolic syndrome which is a collection of risk factors such as high cholesterol, insulin resistance and high blood pressure. (nestle-family.com)
Patients with diabetes hospitalized for Covid-19 present with high-risk features. (biomedcentral.com)
Hence, many effects of nutrition on the development and progression of cancer lack 'specificity' in their association, and such alimentary cues also affect the risk of developing metabolic syndrome, a prelude to arteriosclerosis and neurodegeneration ( Fig. 1 ). (nature.com)
But based on what we know about the causal factors behind metabolic syndrome, there is potential for green tea to be acting at least in part at the gut level to alleviate the risk for either developing it or reversing it if you already have metabolic syndrome. (integrativepractitioner.com)
Obesity, endogenous hormones, and endometrial cancer risk: a synthetic review. (scienceopen.com)
In our overall synthesis, we conclude that development of ovarian hyperandrogenism may be a central mechanism relating nutritional lifestyle factors to endometrial cancer risk. (scienceopen.com)
The metabolic syndrome requires aggressive control of cardiovascular and metabolic risk factors. (medscape.com)
A previous cohort study reported a strong relationship between metabolic syndrome and an increased risk of mortality [ 2 ]. (hindawi.com)
Morbid obesity is associated with a number of comorbidities that enhance the risk of mortality. (symptoma.com)
The application of WHtR provides an alternative anthropometric index of central obesity that avoids the limitations of WC because the inclusion of height into the index enhances the avoidance of any potential confounding of cardiometabolic risk by height [ 19 ]. (hindawi.com)
The basic risk factor for development of asthma remain complex and it is established that genetics and the environments overlap with other factors like obesity and gastroesophageal reflux disease (GERD) to influence asthma [ 6 ]. (biomedcentral.com)
Risk factors for the metabolic syndrome can be identified already in healthy 4-year olds, especially in girls," she said. (rejuvenation-science.com)
Their offspring tend to have higher birth weights and more body fat, and carry an increased risk of obesity later in life. (karger.com)
Risk associated with the metabolic syndrome versus the sum of its individual components. (mja.com.au)
The metabolic syndrome is prevalent and is associated with a greater risk of atherosclerotic cardiovascular disease than any of its individual components. (naturalayurvedictreatment.com)
Lifestyle habits are important modifiable risk factors that can effectively contribute to the reduction of obesity from an early age. (bvsalud.org)
Features of related risk factors for cardiovascular disease may be present, even with a mild degree of hyperglycemia. (medscape.com)
The aim is to determine the body mass index (BMI), the risk level, and the presence of truncal obesity. (medscape.com)
Despite a significant increase in research on pediatric obesity since the initial publication of these guidelines 8 years ago, further study is needed of the genetic and biological factors that increase the risk of weight gain and influence the response to therapeutic interventions. (medscape.com)

In animals, activation of the protein ataxia telangiectasia mutated (ATM) using the antimalarial drug chloroquine improves features of metabolic syndrome and decreases atherosclerosis, a build-up of fatty plaque within arteries. (druglib.com)
Post-mortem analyses of coronary arteries have indicated that obesity (associated with a high accumulation of abdominal fat measured at autopsy) was predictive of earlier and greater extent of large vessels atherosclerosis as well as increase of coronary fatty streaks. (researchgate.net)
These potential signaling mediators include glucose, free fatty acids, autonomic nerves, fat-derived hormones (eg, adiponectin), and the gut hormone glucagonlike peptide-1 (GLP-1). (medscape.com)
Therefore, we evaluated the effect of ACE on major manifestations of metabolic syndrome including obesity, hyperlipidemia, and fatty liver using a high-fat diet mouse model. (hindawi.com)
The metabolic counterpart is excess lipolysis driving fatty acid levels, cathecholamine-induced peripheral, hepatic insulin resistance and fatty liver disease. (kauveryhospital.com)
The myocardium is capable of sustained function using fuels not limited to acetate, glucose or long-chain fatty acids - it is indeed a metabolic omnivore. (kauveryhospital.com)
In obesity, the myocardium abnormally utilises fatty acids and shows an impaired ability to shift away from this increased fatty acid utilization. (kauveryhospital.com)
Astaxanthin raises the production of adiponectin (an adipose-specific protein), which stimulates fatty acid oxidation in obese individuals with insulin resistance 4 , thus a reduction in fasting blood glucose 5 . (optixanthin.com)
Aniamls fed GW-501516 along with a calorie-dense diet showed reducded obesity and improved insulin resistance, effects that were accompanied by enhanced metabolic rate and fatty acid β-oxidation, proliferation of mitochondria (the powerhouses of cells), and a significant reduction of lipid fat droplets in skeletal muscles. (umbrellalabs.is)

In this CPR, we discuss the management of obesity and metabolic syndrome (O&MS) in children and adolescents with CKD stages 2-5 and on dialysis, as well as after kidney transplantation, focusing on non-pharmacological treatment (diet, physical activity and behavior modification). (springer.com)
A systematic review done among the young in 2020 showed that globally, about 3% of children and 5% of adolescents had Metabolic Syndrome , with some variation across countries and regions. (lowcarbneurologist.com)
Is metabolic and bariatric surgery a safe and effective therapeutic option for adolescents with severe obesity? (medscape.com)
Pediatric obesity remains an ongoing serious international health concern affecting ~17% of US children and adolescents, threatening their adult health and longevity. (medscape.com)
Adolescents undergoing lifestyle therapy, medication regimens, or bariatric surgery for obesity will need cohesive planning to help them effectively transition to adult care, with continued necessary monitoring, support, and intervention. (medscape.com)

IR is defined as cellular resistance to insulin stimulated glucose uptake. (biomedcentral.com)
Insulin resistance is a state wherein certain cells of the body (e.g. the muscle cell) do not efficiently use insulin for glucose uptake. (lowcarbneurologist.com)
The body cells are unable to uptake glucose effectively, thus causing the built-up of glucose in the bloodstream. (optixanthin.com)

Led by Richard Bruno, PhD, Msc, professor of human nutrition at The Ohio State University in Columbus, Ohio, a team of researchers studied the effects of green tea extract on blood glucose, gut inflammation, and gut permeability. (integrativepractitioner.com)
This suggests that improving glycemic control might reduce the inflammatory response supporting the link between inflammation and glucose metabolic disturbance. (biomedcentral.com)
While obesity may predispose to increased Th2 inflammation or atopic tendencies, other mechanisms that are independent of inflammatory cells, need to be considered. (biomedcentral.com)

Among women in reproductive age, the obese rural population also found vulnerable to PCOS, indicates the role of lifestyle factors in this syndrome. (ijpsr.com)
Both non-obese and obese PCOS women found vulnerable to the same metabolic consequences. (ijpsr.com)
Hence, further long term, controlled studies are required to understand the exact pathogenesis and metabolic consequences both in obese and non-obese PCOS women. (ijpsr.com)
This review summarizes the major pathological factors linking obesity to diabetes, focussing on current epidemiological data related to obese diabetic patients in the Arab world, the etiology of the disease and the genetic determinants of diabetes and obesity. (who.int)
It has been found that an increase in diacylglycerol species in insulin resistant obese and T2D subjects stimulates the secretion of insulin by the pancreas to maintain a normal glucose level ( 6 ). (frontiersin.org)
The alarming figures on childhood obesity estimate that by 2010 almost 287 million kids will be obese, and the overall obese population could more than double to 700 million by 2015. (rejuvenation-science.com)
The obesity epidemic has resulted in more overweight/obese women before and during pregnancy. (karger.com)
The current obesity epidemic has resulted in an increasing number of overweight and obese women entering pregnancy [ 1 ]. (karger.com)
Malaysia has the highest rate of obesity among Asian countries, with 64% of male and 65% of female population being either obese or overweight 2 . (optixanthin.com)
Despite a modest body weight change relative to placebo-treated mice, GW-501516 treatment also improved diabetes as revealed by the decrease in blood glucose and blood insulin levels in genetically obese animals. (umbrellalabs.is)

The purpose of this study is to evaluate the long-term effectiveness of chloroquine, a protein-activation medication, at reducing the progression of atherosclerosis in patients with the metabolic syndrome. (druglib.com)
GW-501516 SARM studies were famously pioneered by world-class biologist Ronald Evans at the Salk Institute in La Jolla, CA. He regarded GW-501516 as the long sought-after molecule to confer metabolic protection, calling it "a multifaceted therapeutic for metabolic syndrome with the potential to control weight gain, enhance physical endurance, improve insulin sensitivity, and ameliorate atherosclerosis" [1]. (umbrellalabs.is)

Epidemiological studies suggest that the prevalence and severity of obesity have increased to epidemic proportions worldwide, making it a global public health problem. (molvis.org)

Therefore, our study brings attention to the efforts needed to control the progression of central obesity in these domestic migrant workers. (eohp-journal.jp)
Available evidence clearly indicates a rapid progression in the prevalence of obesity worldwide. (researchgate.net)
The temporal profile is consequent to progression of the metabolic derangement, which is characterized by dehydration, electrolyte abnormalities, osmolality, and acid-base disturbances. (medscape.com)

Other names given to this condition include insulin resistance syndrome, dysmetabolic syndrome, and Syndrome X. According to a US national health survey (NHANES 1988-2012), more than 1 in 5 Americans have Metabolic Syndrome. (lowcarbneurologist.com)
This syndrome is also known as Syndrome X, Insulin resistance syndrome, and Dysmetabolic syndrome. (naturalayurvedictreatment.com)

Replication studies identify several genetic variants in Arabs with obesity-linked diabetes. (who.int)
The mechanisms responsible for insulin resistance syndromes include genetic or primary target cell defects, autoantibodies to insulin, and accelerated insulin degradation. (medscape.com)
This heterogeneity of NAFLD is in turn influenced by various factors primarily demographic/dietary factors, metabolic status, gut microbiome, genetic predisposition together with epigenetic factors. (wjgnet.com)
Pediatric obesity has its basis in genetic susceptibilities influenced by a permissive environment starting in utero and extending through childhood and adolescence. (medscape.com)
Genetic screening for rare syndromes is indicated only in the presence of specific historical or physical features. (medscape.com)
Epi)genetic defects of MKRN3 are rare in Asian patients with central precocious puberty. (cdc.gov)
Novel Genetic and Biochemical Findings of DLK1 in Children with Central Precocious Puberty: A Brazilian-Spanish Study. (cdc.gov)
The remaining 7% of genetic causes of gigantism were due to McCune-Albright syndrome (MAS), Carney complex, and MEN1. (medscape.com)

OBJECTIVE -The aim of this study was to examine how the major components of the metabolic syndrome relate to each other and to the development of diabetes using factor analysis. (diabetesjournals.org)
Among 934 nondiabetic and 305 diabetic subjects at baseline, factor analysis was performed using the principle components analysis with varimax orthogonal rotation of continuously distributed variables considered to represent the components of the metabolic syndrome. (diabetesjournals.org)

Metabolic syndrome with and without C-reactive protein as a predictor of coronary heart disease and diabetes in the West of Scotland coronary prevention study. (mja.com.au)

Cardiovascular morbidity and mortality associated with the metabolic syndrome. (mja.com.au)

Morbid obesity or clinically severe obesity is a condition characterized by body mass index (BMI) over 40 kg/m2, and involves serious health consequences. (symptoma.com)

A subset of these patients has concurrent symptoms of excessive daytime sleepiness attributable to their nocturnal breathing disorder and is classified as having obstructive sleep apnoea/hypopnoea syndrome (4-5% of the middle-aged population). (ersjournals.com)
Numerous reports throughout the 19th century and the early part of the 20th century AD gave way to systematically conducted studies on patients with OSAHS and related syndromes 1 . (ersjournals.com)
We investigated features and Covid-19 outcomes for patients with or without diabetes, and with or without cardiometabolic multimorbidity. (biomedcentral.com)
La présente analyse récapitule les facteurs pathologiques majeurs liant l'obésité au diabète, en se concentrant sur les données épidémiologiques actuelles relatives aux patients diabétiques obèses dans le monde arabe, l'étiologie de la maladie et les déterminants génétiques du diabète et de l'obésité. (who.int)
Metabolic syndrome prevalence is high in the population of asthma patients studied. (biomedcentral.com)
A new study finds that adipocyte SLC7A10 impairments may impact lipid accumulation during insulin resistance in patients with obesity. (medscape.com)
Krampe, S. , de Andrade, N. , da Silveira, L. and Brenol, C. (2020) Prevalence and Incidence of Metabolic Syndrome in a Cohort of Patients with Rheumatoid Arthritis: A Correlation between Body Mass Index and Disease Activity. (scirp.org)
Patients with another connective tissue disease (except for secondary Sjögren's syndrome) were excluded. (scirp.org)
Refractory hypokalemia can be the presenting feature in patients with ectopic ACTH syndrome (EAS), and is seen in up to 80% of cases. (invisionzone.com)
Patients taking medicines for lowering glucose levels or fasting blood sugar higher than 100. (naturalayurvedictreatment.com)
Patients may present with the unexplained weight loss and easy fatigability that result from reduced glucose use and increased catabolism. (medscape.com)
Patients with impaired glucose homeostasis are generally asymptomatic. (medscape.com)
Outcomes of Patients with Central Precocious Puberty Due to Loss-of-Function Mutations in the MKRN3 Gene after Treatment with Gonadotropin-Releasing Hormone Analog. (cdc.gov)

Astaxanthin's antioxidant property helps to protect pancreatic β-cells against oxidative stress induced by high blood glucose levels. (optixanthin.com)

Results showed that fasting blood glucose levels were significantly reduced in all participants. (integrativepractitioner.com)
however, this may vary significantly by age, dietary habits, gender, and even among participants with morbid obesity [ 9 ]. (hindawi.com)
The pulmonary function test was not significantly affected by presence of metabolic syndrome. (biomedcentral.com)
Also, the microvascular tone and microvascular density are significantly impacted by obesity. (kauveryhospital.com)

In contrast, 11beta-HSD-1 knockout mice resist visceral obesity and diabetes through improved function of insulin in liver and adipose tissues. (genengnews.com)

In moderate-to-severe obstructive sleep apnoea/hypopnoea syndrome, treatment with continuous positive airway pressure has been shown to be effective. (ersjournals.com)
The epidemiology of obstructive sleep apnoea (OSA)/hypopnoea syndrome (OSAHS) has been described in a significant number of studies. (ersjournals.com)

By developing novel tools and harnessing the power of metabolomics, proteomics and functional genomics, our lab will define 1) how the lysosome communicates with other cellular compartments to fulfill the metabolic demands of the cell under various metabolic states, 2) and how its dysfunction leads to rare and common human diseases. (stanford.edu)
We apply this knowledge to understand how lysosomal dysfunction leads to human diseases including neurodegeneration, cancer and metabolic syndrome. (stanford.edu)
This study aims to investigate the relationship between triglyceride glucose index (TyG) and erectile dysfunction (ED) among United States (US) adult males. (frontiersin.org)
Due to the prevalence of erectile dysfunction and its increasing occurrence among young men ( 9 ), prevention of erectile dysfunction, which may be directly related to metabolic psychospiritual culture, should be a priority ( 10 ). (frontiersin.org)
Executive dysfunction in Klinefelter syndrome: associations with brain activation and testicular failure. (medscape.com)
This syndrome involves anovulation or ovulatory dysfunction and androgen excess of unclear etiology. (msdmanuals.com)

The medicinal plants Artemisia iwayomogi ( A. iwayomogi ) and Curcuma longa ( C. longa ) radix have been used to treat metabolic abnormalities in traditional Korean medicine and traditional Chinese medicine (TKM and TCM). (hindawi.com)
The results from this study suggest that ACE has the pharmaceutical potential reducing the metabolic abnormalities in an animal model. (hindawi.com)
In traditional Korean medicine (TKM) and traditional Chinese medicine (TCM), metabolic abnormalities are considered indicative of " dampness/phlegm " ( 濕痰 ) and " blood stasis " ( 瘀血 ) [ 6 ]. (hindawi.com)
Abnormalities in myocardial fuel substrate selection in obesity have been noted. (kauveryhospital.com)

thus, insulin resistance results in increased insulin secretion to maintain normal glucose and lipid homeostasis. (medscape.com)
In this study, the authors defined the role of peroxisome proliferator-activated receptor β/δ (PPARδ) in metabolic homeostasis by using subtype selective activators. (umbrellalabs.is)
These hormones regulate the body's growth, and are involved in cell to cell communication, control metabolic activity, sleep-wake homeostasis, and altered regulation or dysregulation of adaptive response in various physiologic and pathophysiologic states. (medscape.com)

The aim of the present study was to compare the effects of nebivolol or atenolol on central and peripheral systolic blood pressure (SBP) and its variability and target organ damage (TOD) in N-nitro-L-arginine methyl ester (L-NAME) hypertensive rats. (bvsalud.org)

0.91) had a higher incidence of metabolic syndrome/diabetes than those in the low quotient group (25 vs. 8% p = 0.04). (frontiersin.org)

Anatomy12

Organisms6

Diseases77

Chemicals and Drugs46

Analytical, Diagnostic and Therapeutic Techniques and Equipment56

Psychiatry and Psychology9

Phenomena and Processes50

Anthropology, Education, Sociology and Social Phenomena4

Technology, Industry, Agriculture6

Information Science4

Named Groups6

Health Care41

Geographicals13

Hypertension25

Dyslipidemia4

Intolerance8

Type 2 Diabet15

Abdominal obesity17

Hyperinsulinemia6

MetS16

Tolerance3

Disorders11

Adipose tissue3

Diabetes mellitus3

Circumference3

People with metabolic syndrome2

Endocrine4

Polycystic6

Lipid profile2

Triglycerides2

Serum2

Chronic3

Clinical16

Waist3

Diagnosis4

Prevalence of metabolic syndrome2

Sedentary lifestyle2

Increases5

Phenotype3

Complications3

Adiposity2

Risk21

Fatty9

Adolescents5

Uptake3

Inflammation3

Obese10

Atherosclerosis2

Epidemic1

Progression3

Insulin Resistan2

Genetic8

Components of the metabolic syndrome2

Coronary heart d1

Morbidity and morta1

Condition characterized1

Patients13

High blood glucose levels1

Significantly4

Visceral obesity1

Obstructive sleep2

Dysfunction6

Abnormalities4

Homeostasis3

Peripheral1

Incidence1