• The physiologic role of lipases is to hydrolyze triglycerides into diglycerides, monoglycerides, fatty acids, and glycerol. (affygility.com)
  • They catalyze the hydrolysis and the synthesis of esters formed from glycerol and long-chain fatty acids. (edu.ng)
  • They play important roles in the hydrolysis of triglycerides to free fatty acids and glycerol as commercial biocatalysts. (edu.ng)
  • Lipases (triacylglycerol acyl hydrolases, E.C. 3.1.1.3), are a family of enzymes that catalyzetheconversion of triacylglycerol to glycerol and fatty acids. (edu.ng)
  • A group of 16-carbon fatty acids that contain no double bonds. (lookformedical.com)
  • Fatty acids are saturated and unsaturated (FATTY ACIDS, UNSATURATED). (lookformedical.com)
  • FATTY ACIDS found in the plasma that are complexed with SERUM ALBUMIN for transport. (lookformedical.com)
  • These fatty acids are not in glycerol ester form. (lookformedical.com)
  • Covalent attachment of LIPIDS and FATTY ACIDS to other compounds and PROTEINS. (lookformedical.com)
  • Triglycerides are a type of fat found in the blood that are made up of three fatty acids and a glycerol molecule. (lookformedical.com)
  • A group of fatty acids that contain 18 carbon atoms and a double bond at the omega 9 carbon. (lookformedical.com)
  • A group of compounds that are derivatives of octadecanoic acid which is one of the most abundant fatty acids found in animal lipids. (lookformedical.com)
  • Carboxylic acids. (lookformedical.com)
  • This group of compounds includes amino acids and fatty acids. (lookformedical.com)
  • Carboxylic acids can be saturated, unsaturated, or aromatic. (lookformedical.com)
  • For example, the set of carboxylic acids that are best known as the intermediates in the citric acid cycle are present in all known organisms, being found in species as diverse as the unicellular bacterium Escherichia coli and huge multicellular organisms like elephants. (wikipedia.org)
  • Lipids are the polymers of fatty acids[citation needed] that contain a long, non-polar hydrocarbon chain with a small polar region containing oxygen. (wikipedia.org)
  • a glycerol molecule attached to three fatty acids by ester linkages is called a triacylglyceride. (wikipedia.org)
  • Diacylglycerols can have many different combinations of fatty acids attached at both the C-1 and C-2 positions. (hmdb.ca)
  • 10. The liquid laundry detergent composition of claim 1 further comprising a fatty acid soap selected from the group consisting of sodium salts of saturated C 12 -C 18 carboxylic acids, sodium salts of unsaturated C 12 -C 18 carboxylic acids, potassium salts of saturated C 12 -C 18 carboxylic acids, potassium salts of unsaturated C 14 -C 18 carboxylic acids, and mixtures thereof. (patentsencyclopedia.com)
  • Triglycerides are esters of three molecules of fatty acids and one molecule of glycerol. (studybaba.in)
  • These protein consist of hydrolases that degrade protein and nucleic Procyclidine HCl acids (25, 33). (lacbiosafety.org)
  • PON1 also catalyzes the reverse reaction, lactonization, of γ- and δ-hydroxy-carboxylic acids. (biochemia-medica.com)
  • in diabetic ketoacidosis, when the conversion of fatty acids to ketones increases. (unboundmedicine.com)
  • Organophosphorous compounds (OPCs) is a large group of chemical substances that represent esters, amides or thiol derivatives of phosphorous, alkyl phosphorous, thiophosphoric and thiophosphonic acids. (kiev.ua)
  • The enzyme fatty-acyl-ethyl-ester synthase (EC 3.1.1.67) catalyzes the reaction a long-chain-fatty-acyl ethyl ester + H2O ⇌ {\displaystyle \rightleftharpoons } a long-chain-fatty acid + ethanol This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. (wikipedia.org)
  • The systematic name is long-chain-fatty-acyl-ethyl-ester acylhydrolase. (wikipedia.org)
  • Catalysis of the reaction: a long-chain-acyl ethyl ester + H2O = a long-chain carboxylic acid + ethanol. (planteome.org)
  • Link to all annotated objects annotated to fatty-acyl-ethyl-ester synthase activity. (planteome.org)
  • Link to all direct and indirect annotations to fatty-acyl-ethyl-ester synthase activity. (planteome.org)
  • Lipases are triacylglycerol acyl hydrolases with the enzyme number EC 3.1.1.3. (edu.ng)
  • Enzymes from the transferase class that catalyze the transfer of acyl groups from donor to acceptor, forming either esters or amides. (lookformedical.com)
  • Duck acyl-[acyl-carrier protein] hydrolase, medium chain (EC 3.1.2.14 ), an enzyme that may be associated with peroxisome proliferation and may play a role in the production of 3-hydroxy fatty acid diester pheromones. (expasy.org)
  • These are glycerolipids lipids containing a common glycerol backbone to which at least one fatty acyl group is esterified. (hmdb.ca)
  • TG(12:0/14:0/18:1(9Z)) belongs to the family of triradyglycerols, which are glycerolipids lipids containing a common glycerol backbone to which at least one fatty acyl group is esterified. (ymdb.ca)
  • Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. (ymdb.ca)
  • Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons). (expasy.org)
  • Lipase enzyme is part of the hydrolase family which breaks triglycerides into simpler fatty acid chains by acting on the carboxylic ester bond. (bioveningredients.com)
  • The carboxylic ester hydrolases certainly are a different band of enzymes that may divide the carboxylic acidity ester connection in carboxylic esters, triglycerides, phospholipids, and/or acetylcholine (34) and therefore may play essential roles in tissues invasion and nutritional utilization by bacterias. (lacbiosafety.org)
  • Acetylcholinesterase and cholinesterase II are closely related enzymes that hydrolyze choline esters [ 4 ]. (expasy.org)
  • C 20 H 32 O 2 , an omega-6 fatty acid formed by the action of enzymes on phospholipids in cell membranes. (unboundmedicine.com)
  • Lipase enzyme breaks these fats into simple and soluble forms of glycerols and free fatty acid, so that our body can utilize them for energy. (bioveningredients.com)
  • Phenmedipham hydrolase (phenylcarbamate hydrolase), an Arthrobacter oxidans plasmid-encoded enzyme (gene pcd) that degrades the phenylcarbamate herbicides phenmedipham and desmedipham by hydrolyzing their central carbamate linkages. (expasy.org)
  • An enzyme of the hydrolase class that catalyzes the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. (ouhsc.edu)
  • Enzyme immobilisation technology is an effective means to improve sugar ester production through the employment of biocatalysts. (researchgate.net)
  • So it is assumed that the native activity of PON1 may be lactonase activity and that physiological substrate may be some lactones which are consumed as food ingredients, drug metabolites (statins, spironolactone and glucocorticoid γ-lactones) and derivatives of fatty acid oxidation process such as 5-hydroxy6E,8Z,11Z,14Z-eicosatetraenoic acid (5-HETE) lactone that resides in HDL (13). (biochemia-medica.com)
  • These are o-ester derivatives of dithiophosphates, with the general structure RSP(O)(O)=S (R = organyl group). (t3db.ca)
  • Lipases (EC 3.1.1.3) is a triacylglycerol acylhydrolase that works on carboxylic ester linkages. (edu.ng)
  • It is a glyceride consisting of two fatty acid chains covalently bonded to a glycerol molecule through ester linkages. (hmdb.ca)
  • These are glycerides consisting of three fatty acid chains covalently bonded to a glycerol molecule through ester linkages. (ymdb.ca)
  • Lipases are part of the family of hydrolases that act on carboxylic ester bonds. (affygility.com)
  • In addition to their natural function of hydrolyzing carboxylic ester bonds, lipases can catalyze esterification, interesterification, and transesterification reactions in nonaqueous media. (affygility.com)
  • Monoacylglycerol lipases (MGL) are a subclass of lipases that predominantly hydrolyze monoacylglycerol (MG) into glycerol and fatty acid. (inra.fr)
  • Extending this work, immobilised lipases have novel capabilities in the synthesis of sugar esters. (researchgate.net)
  • The GH19 Engineering Database: sequence diversity, substrate scope, and evolution in glycoside hydrolase family 19. (uni-stuttgart.de)
  • The protein encoded by this gene belongs to a large family of proteins defined by an alpha/beta hydrolase fold, and contains three sequence motifs that correspond to a catalytic triad found in the esterase/lipase/thioesterase subfamily. (thermofisher.com)
  • Another type or sort of hydrolase, carboxylic esterase, continues to be discovered in the supernatant of GAS, and convalescent-phase sera from sufferers with streptococcal pharyngitis possess esterase-specific antibodies (11, 12, 32). (lacbiosafety.org)
  • A coenzyme A derivative which plays a key role in the fatty acid synthesis in the cytoplasmic and microsomal systems. (lookformedical.com)
  • Phosphatidic acid is then de-phosphorylated to form diacylglycerol.Diacylglycerols are precursors to triacylglycerols (triglyceride), which are formed by the addition of a third fatty acid to the diacylglycerol under the catalysis of diglyceride acyltransferase. (hmdb.ca)
  • Docosahexaenoic Acid methyl ester is a methylated docosahexaenoic acid analog which can be intercalated into membrane phospholipids without being oxidized or hydrolyzed [1][2]. (medchemexpress.com)
  • Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain a carboxy terminated eight carbon aliphatic structure. (lookformedical.com)
  • A fatty acid coenzyme derivative which plays a key role in fatty acid oxidation and biosynthesis. (lookformedical.com)
  • Mutations in this gene have been associated with Chanarin-Dorfman syndrome, a triglyceride storage disease with impaired long-chain fatty acid oxidation. (thermofisher.com)
  • belongs to the class of organic compounds known as dithiophosphate o-esters. (t3db.ca)
  • The optimised conditions for sugar fatty acid ester syntheses are 48 h at 2:1 of molar ratio of lactose sugar to capric acid at 55 °C. Furthermore, a high operational stability with half-lives of over 13 and 10 runs was achieved for NER-CRL and Amino-CRL, respectively, indicating the efficiency of the immobilisation process. (researchgate.net)
  • A specific overview regarding synthetic methodologies and properties of 6′-lactose-based surfactants is presented herein, particularly all the synthetic approaches to this class of lactose esters, such as enzymatic and traditional organic syntheses. (researchgate.net)
  • In addition, PON1 hydrolyzes aromatic esters like phenylacetate, thiophenylacetate and 2-naphthylacetate and different aromatic and aliphatic lactones as well as cyclic carbonates like homogentisic acid lactone, dihydrocoumarin, γ-butyrolactone and homocysteine thiolactone. (biochemia-medica.com)
  • Biological applications with a focus on permeability enhancing, antimicrobial activity, and antibiofilm properties of 6′-lactose-based esters are also reported. (researchgate.net)
  • Plant-produced recombinant LipA is active towards p -nitrophenol esters of various carbon chain lengths with peak activity on medium-chain fatty acid (C8). (biomedcentral.com)
  • In this study, we investigated the in vitro inhibitory effects of the individual major cannabinoids and metabolites ∆9-tetrahydrocannabinol (THC), cannabidiol (CBD), cannabinol (CBN), 11-nor-THC-carboxylic acid, and 11-hydroxy-THC on CES1 activity. (aspetjournals.org)
  • Structurally, MGLs belong to the alpha/beta hydrolase fold family with a cap covering the substrate binding pocket. (inra.fr)
  • Altered lipid metabolism and inflammation are involved in the pathogenesis of both non-alcoholic fatty liver disease (NAFLD) and cardiovascular disease (CVD). (omeka.net)
  • Docosahexaenoic acid-d 5 methyl ester is the deuterium labeled Docosahexaenoic Acid methyl ester. (medchemexpress.com)
  • It is an amino acid derivative and an essential cofactor for fatty acid metabolism. (lookformedical.com)
  • With a very high molar proportion of fatty acid to saccharide when compared to the other studies, the authors suggested that increasing the proportion of fatty acid could negatively affect the lipase conformation due to an acidification of the reaction medium. (researchgate.net)
  • Required for mobilization of steryl ester, thereby playing a central role in lipid metabolism. (ymdb.ca)
  • A saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils. (lookformedical.com)
  • An unsaturated fatty acid that is the most widely distributed and abundant fatty acid in nature. (lookformedical.com)
  • Lipocalin‐2 Protects Against Diet‐Induced Nonalcoholic Fatty Liver Disease by Targeting Hepatocytes. (omeka.net)
  • 5 to about 8, and where M is an alkali metal or ammonium cation;b. from about 1% to about 10% by weight of a fatty alcohol ethoxylate of general formula R--(OCH 2 CH 2 V--OH. (patentsencyclopedia.com)
  • A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids. (lookformedical.com)
  • Although 6:2 fluorotelomer carboxylic acid (6:2 FTCA), which is one of the most popular substitutes for perfluorooctanoic acid (PFOA), has been widely distributed in environments, little is known about its biotransformation mechanism and phytotoxic effects in plants. (bvsalud.org)
  • c) Phosphodiester bond: This is the bond present between the phosphate and hydroxyl group of sugar which is called an ester bond. (studybaba.in)