Fatty acids fatty acid synthase type ii. Medical search. Frequent questions

Polyketide synthases use a similar mechanism and homologous domains to produce secondary metabolite lipids. (wikipedia.org)
or anabolic - the building up (synthesis) of compounds (such as proteins, carbohydrates, lipids, and nucleic acids). (wikipedia.org)
Most of the structures that make up animals, plants and microbes are made from four basic classes of molecules: amino acids, carbohydrates, nucleic acid and lipids (often called fats). (wikipedia.org)
Lipids are the polymers of fatty acids[citation needed] that contain a long, non-polar hydrocarbon chain with a small polar region containing oxygen. (wikipedia.org)
The carboxyl group of mycolic acids is vertically covalently linked to the hydroxyl group of arabino-galactan by ester bond, arabino-galactan is linked to the peptidoglycan layer by phospholipid bond, whereas other glycolipids and free lipids are regularly distributed in the thicker layer of mycolic acids [ 3 , 4 , 5 ]. (biomedcentral.com)
As an important intermediate metabolite, acetyl-coA not only participates in tricarboxylic acid cycle as well as the glyoxylate cycle but also provides carbon source for the synthesis of mycolic acid and lipids [ 8 , 9 ]. (biomedcentral.com)
Very long-chain fatty acids (VLCFAs) possess more than twenty carbon atoms and are the major components of seed storage oil, wax, and lipids. (nature.com)
Interestingly, lipids (mainly keto-mycolic acids) are proposed to be the primary component of extracellular polymeric substance (EPS) in the pellicle biofilm, whereas the leukocyte lysate-induced and thiol reductive stress-induced biofilms possess polysaccharides as the primary component of EPS. (microbialcell.com)
Serum fatty acids and other serum lipids(triglycerides and total, HDL and LDL cholesterol), as well as markers of inflammation (leptin, and C-reactive protein) and glucose regulation (glucose and hemoglobin A1c) were assessed from fasting participants at baseline and after the intervention. (biomedcentral.com)

Fatty acid synthase (FAS) is an enzyme that in humans is encoded by the FASN gene. (wikipedia.org)
Fatty acid synthase (FASN) is a central regulator of lipid metabolism. (immune-system-research.com)
FASN provides the fatty acids needed to sustain tumor growth, as a potential target for human malignant tumors. (immune-system-research.com)
The expression of regulatory molecules, TGF-β1/2, phospho-Akt (Ser473), PPARα, sterol regulatory element-binding protein 1 (SREBP-1), fatty acid synthase (FASN), hormone-sensitive lipase (HSL), and acyl dehydrogenases was analyzed in virus-infected hepatocytes. (academic-accelerator.com)
Fatty acid synthase (FASN) is frequently activated and overexpressed in human cancers, and plays a crucial role in the carcinogenesis of various cancers. (biomedcentral.com)
Caco-2 cells with a high expression of both HER2 and FASN were selected for functional characterization. (biomedcentral.com)
Caco-2 cells were transfected with either the FASN specific RNAi plasmid or the negative control RNAi plasmid, followed by the RT-qPCR and western blot to examine the expression of FASN, HER2, PI3K and Akt. (biomedcentral.com)
Fatty acid synthase (FASN) is a homodimeric multienzymatic protein which can be divided into seven functional domains that are assembled into two homodimers [ 1 ]. (biomedcentral.com)

Amino acids also contribute to cellular energy metabolism by providing a carbon source for entry into the citric acid cycle (tricarboxylic acid cycle), especially when a primary source of energy, such as glucose, is scarce, or when cells undergo metabolic stress. (wikipedia.org)
Through a series of chemical reactions of pyruvate decarboxylation, the glycolytic pathway (the final product is pyruvate) and the tricarboxylic acid cycle (the initial reactant is acetyl-coA) can be effectively connected [ 7 ]. (biomedcentral.com)
A group of these diseases are due to defects of mitochondrial carriers, a family of proteins named solute carrier family 25 (SLC25), that transport a variety of solutes such as the reagents of ATP synthase (ATP, ADP, and phosphate), tricarboxylic acid cycle intermediates, cofactors, amino acids, and carnitine esters of fatty acids. (nih.gov)

In these bacteria, the FAS I system produces palmitic acid, and cooperates with the FAS II system to produce a greater diversity of lipid products. (wikipedia.org)
Electric pulse stimulation inhibited lipid accumulation on C2C12 myotubes incubated with oleic acid and palmitic acid. (academic-accelerator.com)
He localized the biologic activity to a fraction of lipid soluble acids that he termed "prostaglandin," hypothesizing that these substances originate in the prostate gland. (medscape.com)

Proteins are made of amino acids arranged in a linear chain joined by peptide bonds. (wikipedia.org)
To solve this dilemma, cells must use their own proteins as sources of amino acids in response to the nutritional downshift. (go.jp)
Utilizing two further mutants of low-adhesive FimH proteins via Ersus. (phosphorylasesignals.com)
The phosphorylation of a given sugar requires four proteins, two general proteins, Enzyme I and HPr and a pair of sugar-specific proteins designated as the Enzyme II complex. (nih.gov)
They have been defined as monotropic integral membrane proteins located primarily in the endoplasmic reticulum (COX-1) and the perinuclear envelope (COX-2). (medscape.com)

The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. (nih.gov)

Type II is found in archaea, bacteria and plant plastids, and is characterized by the use of discrete, monofunctional enzymes for fatty acid synthesis. (wikipedia.org)
The mechanism of FAS I and FAS II elongation and reduction is the same, as the domains of the FAS II enzymes are largely homologous to their domain counterparts in FAS I multienzyme polypeptides. (wikipedia.org)
However, the differences in the organization of the enzymes - integrated in FAS I, discrete in FAS II - gives rise to many important biochemical differences. (wikipedia.org)
The solved structures of yeast FAS and mammalian FAS show two distinct organizations of highly conserved catalytic domains/enzymes in this multi-enzyme cellular machine. (wikipedia.org)
En combinant une approche in silico et la validation in vitro de l'activité des protéines, nous avons récemment mis en évidence des propriétés structurales et la sélectivité de substrat de ces enzymes. (ipbs.fr)
Because both of these cofactors are missing, the enzymes that require them (methylmalonyl CoA mutase and methionine synthase) do not function normally. (medlineplus.gov)
For example, in an environment rich in amino acids, cells do not expend energy for making amino acid biosynthetic enzymes. (go.jp)
However, if the environment becomes depleted of amino acids (nutritional downshift), cells will be exposed to a lack of both the amino acid biosynthetic enzymes and the amino acids required to make these enzymes. (go.jp)
Once amino acid biosynthetic enzymes start to accumulate, the cell is able to produce its own amino acids, and a new growth phase begins. (go.jp)
This disease is mainly regulated by various enzymes and hormones among which Glycogen synthase kinase-3 (GSK-3) is a principle enzyme and insulin is the key hormone regulating it. (scielo.br)
There is a growing body of evidence in both human and animal studies that indicates that n-3 LcPUFAs inhibit inflammation by altering the transcription of key inflammatory genes and by competing with the n-6 LcPUFA, arachidonic acid (ARA), for key enzymes participating in pro-inflammatory eicosanoid biosynthesis (Figure 1 ) [ 19 , 20 ]. (biomedcentral.com)
The biosynthesis of n-6 and n-3 PUFAs proceeds in parallel pathways utilizing the same set of fatty acid desaturase (FADS) and elongase (ELOVL) enzymes. (biomedcentral.com)

We used a fluorescence HPLC assay for quantitation of membrane phospholipids metabolically prelabelled with oxidation-sensitive natural fluorescent fatty acid, cis-parinaric acid (PnA). (cdc.gov)
We found that a combination of phenol /arachidpnic acid or cresol/rachidonic acid caused a pronounced oxidation of major phospholipids: phosphatidytcholine, phosphatidylethanolamine, and phosphatidylserine in keratinocytes. (cdc.gov)
Activation of adiponectin receptors (AdipoRs) by its natural ligand, adiponectin has been known to be involved in modulating critical metabolic processes such as glucose metabolism and fatty acid oxidation as demonstrated by a number of in vitro and in vivo studies over last two decades. (phoenixpeptide.com)
Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). (nih.gov)

Fatty acid synthase is a multi-enzyme protein that catalyzes fatty acid synthesis. (wikipedia.org)
The growing fatty acid chain is carried between these active sites while attached covalently to the phosphopantetheine prosthetic group of an acyl carrier protein (ACP), and is released by the action of a thioesterase (TE) upon reaching a carbon chain length of 16 (palmitic acid). (wikipedia.org)
Now, researchers at Washington University School of Medicine in St. Louis have shown that high levels of a specific protein circulating in the blood accurately detect a severe type of peripheral artery disease that narrows the arteries in the legs and can raise the risk of heart attack and stroke. (technologynetworks.com)
The protein, called circulating fatty acid synthase (cFAS), is an enzyme that manufactures saturated fatty acids. (technologynetworks.com)
The MMADHC gene provides instructions for making a protein that helps convert vitamin B12 (also called cobalamin) into one of two molecules, adenosylcobalamin (AdoCbl) or methylcobalamin (MeCbl). (medlineplus.gov)
This enzyme helps break down certain protein building blocks (amino acids), fat building blocks (fatty acids), and cholesterol. (medlineplus.gov)
Longer-term (24 and 48 h) treatment reduced the expression of lipogenic markers (FA synthase and sterol regulatory element-binding protein-1) and increased the expression of lipolytic [hormone-sensitive lipase (HSL) and adipose triglyceride lipase (ATGL)] and mitochondrial (peroxisome proliferator-activated receptor γ coactivator-1α and carnitine palmitoyltransferase 1) markers. (academic-accelerator.com)
protein_coding" "Cz02g09110.t1","No alias","Chromochloris zofingiensis","2-hydroxy-palmitic acid dioxygenase Mpo1-like [Interproscan]. (ntu.edu.sg)
Measurements with a thiol-reagent, ThioGlo-1 showed that phenol (cresol) + arachidonic acid depleted GSH and oxidized protein sulfuydryls in keratinocytes. (cdc.gov)
We identified a highly conserved, 13-residue segment (ADP-1) from adiponectin's collagen domain which comprises GXXG motifs and has one asparagine and two histidine residues that assist in oligomeric protein assembly. (phoenixpeptide.com)
The transcription of COX-1 yields a 2.7-kilobase (kb) messenger ribonucleic acid (mRNA) that encodes a 576-residue, 65-kd protein. (medscape.com)
Conversely, the transcription of COX-2 yields a 4.5-kb mRNA that encodes a 70-kd protein with roughly 70-75% homology to the COX-1 protein. (medscape.com)
E7 from human papil omavirus type 16 cooperate to cancer: the European prospective investigation into doi:10.1093/carcin/bgp321 PMID:20047954 target the PDZ protein Na/H exchange regulatory cancer and nutrition study. (who.int)

In human epidermis, active metabolism of arachidonic acid to prostaglandins is regulated by prostaglandin H synthase (PHS) which is also known to catalyze xenobiotic biotransformation. (cdc.gov)
To our knowledge this is the first report on identification of a short peptidefrom adiponectin with positive effects on glucose or fatty acid metabolism. (phoenixpeptide.com)

Its main function is to catalyze the synthesis of palmitate (C16:0, a long-chain saturated fatty acid) from acetyl-CoA and malonyl-CoA, in the presence of NADPH. (wikipedia.org)
Over all, this study indicates that aceE gene plays a significant role in the mycolic acid synthesis and affects the colony morphology, biofilm formation of M. smegmatis and bacteria invasion of macrophage. (biomedcentral.com)
Further investigations by Smith concluded that aspirin and indomethacin inhibited synthesis by specifically blocking oxygenation of arachidonic acid. (medscape.com)

It is not a single enzyme but a whole enzymatic system composed of two identical 272 kDa multifunctional polypeptides, in which substrates are handed from one functional domain to the next. (wikipedia.org)
MeCbl is also a cofactor, but for an enzyme known as methionine synthase. (medlineplus.gov)
This enzyme converts the amino acid homocysteine to another amino acid, methionine. (medlineplus.gov)
Glycogen synthase kinase-3 (GSK-3) a magic enzyme: it's role in diabetes mellitus and glucose homeostasis, interactions with fluroquionlones. (scielo.br)

Combination of phenolic compounds with arachidonic acid induces "futile thiol pumping" and oxidative stress in epidermal human keratinocytes. (cdc.gov)
Exposure to phenol (cresol) + arachidonic acid decreased total antioxidant reserves in keratinocytes as measured by luminol-enhanced chemiluminescence in the presence of a water-soluble azo-initiator, AAPH. (cdc.gov)
Electron microscopy revealed characteristic apoptotic nuclear fragmentation in keratinocytes exposed to a combination of phenolic compounds with arachidonic acid. (cdc.gov)
By 1964, after recognition of this basic structure, Bergstrom and colleagues successfully synthesized series 2 prostaglandins from arachidonic acid using sheep seminal fluid. (medscape.com)
Their distinct biosynthetic activity includes an endoperoxidase synthase reaction that oxygenates and cyclizes polyunsaturated fatty acid precursors (eg, arachidonic acid) to form prostaglandin G 2 (PGG2), and a peroxidase reaction that converts PGG2 to prostaglandin H 2 (PGH2), as shown below. (medscape.com)
Cyclooxygenase conversion of arachidonic acid into prostaglandin H2 (PGH2). (medscape.com)

This mutant had obvious differences in colony morphology (smaller plaque, edge smooth and round) and defects in biofilm formation in contrast with the wild-type (WT) strains. (biomedcentral.com)
We support the concept that elevated glucose and fatty acids synergize in causing toxicity in islets and other organs, a process that may be instrumental in the pleiotropic defects associated with the metabolic syndrome and type 1 and type 2 diabetes. (diabetesjournals.org)
Thus the two defects and/or adaptive processes initially walk hand in hand in the progression toward overt diabetes. (diabetesjournals.org)

For example, the set of carboxylic acids that are best known as the intermediates in the citric acid cycle are present in all known organisms, being found in species as diverse as the unicellular bacterium Escherichia coli and huge multicellular organisms like elephants. (wikipedia.org)
It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. (nih.gov)

The analysis of mycolic acid (MA) using LC-MS indicated deficiency of alpha-MA and epoxy-MA in aceE -mut strain whereas complementation of the aceE -mut with a wild-type aceE gene restored the composition of MA. (biomedcentral.com)
Examples of diseases, due to mitochondrial carrier mutations are: combined D-2- and L-2-hydroxyglutaric aciduria, carnitine-acylcarnitine carrier deficiency, hyperornithinemia-hyperammonemia-homocitrillinuria (HHH) syndrome, early infantile epileptic encephalopathy type 3, Amish microcephaly, aspartate/glutamate isoform 1 deficiency, congenital sideroblastic anemia, Fontaine progeroid syndrome, and citrullinemia type II. (nih.gov)

Ingestion of polyunsaturated fatty acids (PUFAs) has been proposed to influence several chronic diseases including coronary heart disease (CHD) and type-2 diabetes (T2D). (biomedcentral.com)

In turn, PGH2 is converted to biologically active products (ie, prostaglandin E 2 [PGE2]) by individual synthase and reductase reactions. (medscape.com)

Two decades later, the prostaglandins were deduced to be a family of related compounds that contain 20-carbon polyunsaturated fatty acids with a cyclopentane ring, as depicted below. (medscape.com)

Variants in the MMADHC gene can cause methylmalonic acidemia with homocystinuria, cblD type, which is one form of a condition that has features of both of the two conditions described above. (medlineplus.gov)
FAE ( Fatty Acid Elongation ) like genes take part in the biosynthesis of VLCFAs, growth regulation, and stress responses, and are further comprised of KCS ( Ketoacyl-CoA synthase ) and ELO ( Elongation Defective Elongase ) sub-gene families. (nature.com)

The BO combination was enriched in alpha-linolenic, gamma-linolenic, and stearidonic acids and the FO in eicosapentaenoic and docosahexaenoic acids. (biomedcentral.com)

Therefore, COX - also known as prostaglandin-endoperoxide synthase (PTGS), fatty acid COX, prostaglandin H (PGH) synthase, and EC 1.14.99.1 - is implicated in the production of fever, inflammation, and pain. (medscape.com)

The fatty acids are synthesized by a series of decarboxylative Claisen condensation reactions from acetyl-CoA and malonyl-CoA. (wikipedia.org)

The expression levels of LPL (lipoprotein lipase), HSL (Hormone-sensitive lipase), FAS (fatty acid synthase), and PPARα/PPARγ (peroxisome proliferator-activated receptor alpha/gamma) were significantly changed in the sheep preadipocytes during differentiation for 7 days. (academic-accelerator.com)

a glycerol molecule attached to three fatty acids by ester linkages is called a triacylglyceride. (wikipedia.org)
In Escherichia coli , amino acid starvation leads to the accumulation of an unusual molecule, polyphosphate (polyP), a linear polymer of many hundreds of orthophosphate residues. (go.jp)

In both strains, mycolic acids had fewer double bond numbers in phenol conditions than the glucose condition, and evol40 had significantly shorter mycolic acid chain lengths than the WT strain in phenol conditions. (biomedcentral.com)
These results indicate that phenol adaptation affected mycolic acid membrane composition. (biomedcentral.com)
Our results suggest that the alteration of the mycolic acid and phospholipid membrane composition may be a strategy of R. opacus for phenol tolerance. (biomedcentral.com)

In this study, 53 KCS genes were identified in B. carinata compared to 32 and 33 KCS genes in B. nigra and B. oleracea respectively, which suggests that polyploidization might has impacted the fatty acid elongation process during Brassica evolution. (nature.com)
The current study provides a basis to understand the evolution of both KCS and ELO genes in fatty acid elongation and their role in stress tolerance. (nature.com)

Meanwhile, triglyceride (TG) content was decreased and lipolysis genes expressions, such as adipose triglyceride lipase (ATGL), hormone sensitive lipase (HSL) and lysosomal acid lipase (LAL) were elevated in the jejunum and ileum of inulin and propionate treated mice. (academic-accelerator.com)
In adipose tissue, NXT reduced fatty acid synthase while activating hormone-sensitive lipase expression. (academic-accelerator.com)

How do Fatty Acyl-CoA's pass the mitochondrial intermembrane space? (flashcardmachine.com)

These findings suggest that AdipoRs' agonists could be developed into a potential therapeutic agent for metabolic diseases, such as diabetes mellitus, especially for type II diabetes, a long-term metabolic disorder characterized by high blood sugar, insulin resistance, and relative lack of insulin. (phoenixpeptide.com)

Therefore, it is the need of the day to properly understand functions and mechanisms of GSK-3, especially its role in glucose homeostasis via effects on glycogen synthase. (scielo.br)
β-Cells possess inherent mechanisms to adapt to overnutrition and the prevailing concentrations of glucose, fatty acids, and other fuels to maintain glucose homeostasis. (diabetesjournals.org)

Glycolipids, porins and lipoarabinomannan as well as its variants, which are anchored to the cell membrane by diacylglycerol, are also essential components [ 2 ]. (biomedcentral.com)
A number of components of the mycobacterial cell wall such as glycopeptidolipids, short chain mycolic acids, monomeromycolyl diacylglycerol, etc. have been shown to play an important role in formation of pellicle biofilms. (microbialcell.com)

The new study suggests that fatty acid synthase also circulates in the bloodstream and may have an important role in the plaque formation characteristic of cardiovascular disease. (technologynetworks.com)
Evidence suggests that COX-1 and COX-2 are similar in structure and function but that they exist as 2 distinct enzymatic entities. (medscape.com)

Type 2 diabetes (T2D) is a major health concern in the United States with an estimated 18.3 million adults having physician-diagnosed diabetes, an additional 7.1 million adults having undiagnosed diabetes and about 81.5 million having prediabetes, also referred to as metabolic syndrome [ 1 ]. (biomedcentral.com)

Although acetoxy derivatives of the 3,13- and 2,13-dienes showed almost the same mass spectra, the alcohols were distinguished by comparing the relative intensities of [M−18] + at m ⁄ z 248, indicating direct differentiation of the two positional isomers without derivatization. (go.jp)

Glucagon-like peptide-1 (GLP-1) is a 30- or 31-amino acid peptide hormone produced and secreted by intestinal enteroendocrine L-cells and certain neurons within the nucleus of the solitary tract in the brainstem upon food consumption. (immune-system-research.com)

FAS I in animals is thought to have arisen through modification of PKS I in fungi, whereas FAS I in fungi and the CMN group of bacteria seem to have arisen separately through the fusion of FAS II genes. (wikipedia.org)
The neutral type of selection seemed to be predominant in both KCS and ELO genes evolution. (nature.com)

Several geometrical isomers of 3,13- and 2,13-octadecadien-1-ols and their acetates were synthesized starting from 1,8-octanediol or 1,9-nonanediol utilizing acetylene coupling reactions. (go.jp)

Yeast FAS has a highly efficient rigid barrel-like structure with 6 reaction chambers which synthesize fatty acids independently, while the mammalian FAS has an open flexible structure with only two reaction chambers. (wikipedia.org)
A diagnosis of Type 2 diabetes and smoking status also were strongly and independently correlated with chronic limb-threatening ischemia. (technologynetworks.com)

One of the key processes in which human body eliminates toxic chemicals as well as hormones (such as estrogen) is by attaching glucuronic acid to them in the liver and then excreting the complex in the bile. (medindex.am)

To enhance its aromatic tolerance, we recently applied adaptive evolution using phenol as a sole carbon source and characterized a phenol-adapted R. opacus strain (evol40) and the wild-type (WT) strain by whole genome and RNA sequencing. (biomedcentral.com)
Twenty-carbon polyunsaturated fatty acid with cyclopentane ring. (medscape.com)

This group is also known for polyploidy studies due to diploid parents and allotetraploid species 2 . (nature.com)
It evolved after natural polyploidization between two diploid species B. nigra (BB, 2n = 2X = 16) and B. oleracea (CC, 2n = 2X = 18) about 0.047 MYA 4 . (nature.com)

Terms that describe the age of onset (juvenile or adult) or type of treatment ( insulin -dependent or non- insulin -dependent) are no longer used because of overlap in age groups and treatments between disease types. (msdmanuals.com)
The growing prevalence of obesity is strongly associated with low-grade systemic inflammation, dyslipidemia, insulin resistance and diabetes, and lifestyle factors including diet are known to play a critical role in the development and progression of T2D [ 2 - 4 ]. (biomedcentral.com)
The traditional view of the pathogenesis of type 2 diabetes is that hyperinsulinemia occurs as a consequence of insulin resistance ( 1 ). (diabetesjournals.org)
In contrast, others have favored the concept that exaggerated insulin secretion will cause insulin resistance ( 3 , 4 ), possibly via fatty acid-mediated impairment of insulin action ( 5 - 7 ). (diabetesjournals.org)

A collagen domain-derived short adiponectin peptide activates APPL1 and AMPK signaling pathways and improves glucose and fatty acid metabolisms. (phoenixpeptide.com)

Ground point out electron affinities for all the main party elements as well as homonuclear diatomics were determined just lately using the normalized presenting vitality with the hydrogen atom: [0.75420375(Three or more)/2=0.37710187(A single) eV]. (phosphorylasesignals.com)
Anion Morse potentials tend to be computed for H-2 and N-2 via good electron affinities as well as for hyperfine superoxide says for the first time.The particular joining attributes of low- along with high-adhesive kinds of FimH adhesins coming from Salmonella enterica serovars Enteritidis and also Typhimurium (Azines. (phosphorylasesignals.com)

L'enveloppe mycobactérienne est unique dans le monde bactérien, tant par sa composition riche en composés structurellement exotiques, que par son agencement, avec notamment la présence d'une membrane externe et d'une membrane interne. (ipbs.fr)

Type 2 diabetes is considered to be in most cases a polygenic disease with a strong involvement of environmental factors, such as diet and exercise ( 1 ). (diabetesjournals.org)

A Type I fatty acid synthase system is also found in the CMN group of bacteria (corynebacteria, mycobacteria, and nocardia). (wikipedia.org)
Until recently, fatty acid synthase was thought to be found only inside cells. (technologynetworks.com)
The researchers also found that cFAS levels in the blood were associated with the fatty acid synthase content of plaque sampled from the femoral artery, the main vessel supplying blood to the legs. (technologynetworks.com)
The calcium salt form of glucaric acid, a natural substance found in many fruits and vegetables, with potential anti-cancer property. (medindex.am)
Fatty acids of this group can be found abundantly in the form of suberins, sphingolipids, leaf cuticles, pollen epidermis, and cork cells. (nature.com)

Anatomy1

Diseases1

Chemicals and Drugs25

Phenomena and Processes1

Information Science2

Lipids9

FASN8

Tricarboxylic acid3

Lipid3

Proteins5

Pathway1

Enzymes12

Oxidation4

Protein13

Metabolism2

Synthesis3

Enzyme4

Arachidonic acid6

Defects3

Intermediates2

Deficiency2

PUFAs1

Reductase1

Compounds1

Gene2

Stearidonic1

Prostaglandin1

Malonyl1

Receptor1

Molecule2

Mycolic acid3

Elongation2

Adipose2

Mitochondrial1

Diabetes mellitus1

Glucose homeostasis2

Diacylglycerol2

Suggests2

Metabolic syndrome1

Differentiation1

Amino acid1

Genes2

Reactions1

Independently2

Hormones1

Carbon2

Species2

Insulin4

Adiponectin1

Electron2

Membrane1

Disease1

Found5