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  • patients
  • Combination of lipoic acid and N-acetylcysteine can stabilize the DNA of blood cells from Fanconi anemia (FA) patients, says study published in Rare Diseases. (medindia.net)
  • Fanconi anemia patients suffer a number of symptoms, including increased sensitivity to chemicals that cross-link DNA strands of the double helix together. (sciencemag.org)
  • FANCC(-/-) mutant male and female mice have compromised gametogenesis, leading to markedly impaired fertility, a characteristic of Fanconi anemia patients. (wikipedia.org)
  • phenotype
  • Such conditions, it is argued, are readily distinguishable from genetic diseases associated with increased mortality, but not associated with an aging phenotype, such as cystic fibrosis and sickle cell anemia. (wikipedia.org)
  • This and further analysis revealed the mouse phenotype to model the human genetic illness, Fanconi anemia. (wikipedia.org)
  • The clinical phenotype of mutational defects in all Fanconi anemia (FA) complementation groups is similar. (wikipedia.org)
  • Families
  • Canadian charity whose mission is to fund medical research into finding a cure for Fanconi Anemia and to serve as a support network for affected Canadian families. (dmoztools.net)
  • blood cells
  • A lack of red blood cells may result in fatigue ( anemia ). (northside.com)
  • While at birth, blood count is usually normal, macrocytosis/megaloblastic anemia, defined as unusually large red blood cells, is the first detected abnormality, often within the first decade of life (median age of onset is 7 years). (wikipedia.org)