• The thrombin receptor, which belongs to the guanine nucleotide binding protein (G protein)-coupled receptor family, has recently been shown to induce rapid tyrosine phosphorylation of cellular proteins. (uthscsa.edu)
  • The results being achieved with novel therapies - including antibody-drug conjugates and chimeric antigen receptor (CAR) T cell therapies - as well as tyrosine kinase inhibitors have led one expert to ask whether it's time for a "curtain call for conventional chemotherapy" in older adults with ALL. (medscape.com)
  • The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). (nih.gov)