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Olfactory BulbOlfactory Receptor NeuronsOlfactory NerveSmellOdorsOlfactory Marker ProteinReceptors, OdorantOlfaction DisordersOlfactory Nerve InjuriesEsthesioneuroblastoma, OlfactoryVomeronasal OrganArthropod AntennaeSensory Receptor CellsNasal CavityPentanolsSense OrgansMushroom BodiesNeuronsPheromonesSensillaNeuropilMonoterpenesOlfactory Nerve DiseasesAxonsBehavior, AnimalNasal MucosaSensory ThresholdsNasal SeptumStimulation, ChemicalCiliaNeurogenesisNeurons, AfferentDendritesInterneuronsBrainDiscrimination (Psychology)Cyclic Nucleotide-Gated Cation ChannelsImmunohistochemistryHabituation, PsychophysiologicAnimals, NewbornNerve Tissue ProteinsBeesManducaMice, Inbred C57BLNoseAssociation LearningAction PotentialsIn Situ HybridizationDiscrimination LearningTelencephalonTurbinatesLateral VentriclesElectrophysiologyIctaluridaeNose NeoplasmsNephropidaeRats, Sprague-DawleyZinc SulfateAnimals, Genetically ModifiedEvoked PotentialsImprinting (Psychology)Chemoreceptor CellsHexanolsEugenolAldehydesMice, TransgenicMemoryGene Expression Regulation, DevelopmentalDrosophila melanogasterDrosophilaSexual Behavior, AnimalNeurogliaTaste DisordersConditioning (Psychology)AnomuraNasal LavageCentral Nervous SystemTrigeminal NerveLarvaSynapsesConditioning, ClassicalReceptors, PheromoneElectric StimulationNerve RegenerationNerve NetProsencephalonOncorhynchus kisutchTime FactorsMothsMolecular Sequence DataNeural InhibitionModels, NeurologicalPatch-Clamp TechniquesKallmann SyndromeRats, Long-EvansLearningCuesBromodeoxyuridineSignal TransductionPerfume
SubfamilyEpitheliumNeuronsAssigned to the olfactory receptorReceptorsBulbMain olfactoryFloralFirenzeSensoryImpairmentChypreDysfunctionFragranceNoseSmellOdorsNervePlaylistMammalianMoleculesDetectsNasalWoodyBulbsBasalClassifyScentsProteinsGenesSystemSmokyMorphologyEpithelialRespiratoryProteinNotesPatchouliMRNAFunctionalMasculineHumanMemberUniverseAdults
Subfamily2
  • Olfactory receptor family 2 subfamily AG member 2 is a protein that in humans is encoded by the OR2AG2 gene. (wikipedia.org)
  • This receptor belongs to the Olfactory Receptor subfamily of GPCRs. (thermofisher.com)
Epithelium9
Neurons8
  • The specialized olfactory epithelial cells characterize the only group of neurons capable of regeneration. (medscape.com)
  • The continuous turnover and new supply of these neurons are unique to the olfactory system. (medscape.com)
  • The receptor cells are actually bipolar neurons, each possessing a thin dendritic rod that contains specialized cilia extending from the olfactory vesicle and a long central process that forms the fila olfactoria. (medscape.com)
  • The small, unmyelinated axons of the olfactory receptor cells form the fine fibers of the first cranial nerve and travel centrally toward the ipsilateral olfactory bulb to make contact with the second-order neurons. (medscape.com)
  • Mitral cells are second-order neurons contacted by the olfactory nerve fibers at the glomerular layer of the bulb. (medscape.com)
  • As humans age, the number of olfactory neurons steadily decreases. (medscape.com)
  • Neurons with the same receptors at their ends run to the same pair of nodes, or glomeruli, in the olfactory bulb. (newscientist.com)
  • In the brain, the CHD7 protein is active in several areas, including a bundle of nerve cells (neurons) called the olfactory bulb that is critical for the perception of odors. (medlineplus.gov)
Assigned to the olfactory receptor1
  • The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. (wikipedia.org)
Receptors7
  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. (wikipedia.org)
  • The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. (wikipedia.org)
  • Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. (wikipedia.org)
  • A unified nomenclature for vertebrate olfactory receptors. (jax.org)
  • Olfactory receptors. (medscape.com)
  • It is a specialized pseudostratified neuroepithelium containing the primary olfactory receptors. (medscape.com)
  • To stimulate the olfactory receptors, airborne molecules must pass through the nasal cavity with relatively turbulent air currents and contact the receptors. (medscape.com)
Bulb8
  • The olfactory bulb lies inferior to the basal frontal lobe. (medscape.com)
  • The olfactory bulb is a highly organized structure composed of several distinct layers and synaptic specializations. (medscape.com)
  • The main olfactory system originates from the olfactory mucosa and projects to the main olfactory bulb (MOB), while the VNO, described by Jacobson in 1813 ( Trotier and Doving, 1998 ) projects to the accessory olfactory bulb (AOB, see Figure 2 ). (frontiersin.org)
  • (C) A horizontal section through the main and accessory olfactory bulb. (frontiersin.org)
  • The arrows indicate the projections from the MOE to the main olfactory bulb (right) and from the VNO to the AOB (left). (frontiersin.org)
  • The altered protein affects the development of the olfactory bulb, which impairs the sense of smell. (medlineplus.gov)
  • It is feasible to argue the hypothesis of the involvement of the foetus' olfactory bulb as one of the indelible pathophysiological manifestations to the clinical diagnosis of COVID-19 with neurosensory olfactory deficit in foetuses and newborns affected by intrauterine infection. (bvsalud.org)
  • Finally, we performed injections of α-synuclein in the olfactory bulb of wild type mice and observed that some of the α-synuclein was taken up by activated microglia that were immunopositive for galectin-3. (lu.se)
Main olfactory1
  • The accessory olfactory system may complement the main olfactory system and may contribute different perceptual features to the construction of a unitary representation, which merges the different chemosensory qualities. (frontiersin.org)
Floral1
  • Click here to find out about all the facets of the olfactory family of floral fragrances. (carrementbelle.com)
Firenze3
  • Surprise the senses with the Special Editions by Dr. Vranjes Firenze: contemporary olfactory décor for timeless fragrances. (drvranjes.us)
  • To surprise with originality and elegance, give the freedom to choose among the Dr. Vranjes Firenze olfactory notes. (drvranjes.us)
  • Unique olfactory experiences: discover the original notes created by Dr. Vranjes Firenze. (drvranjes.us)
Sensory6
  • The olfactory system represents one of the oldest sensory modalities in the phylogenetic history of mammals. (medscape.com)
  • This study aims to investigate if newborn children of women infected with COVID-19 during pregnancy have olfactory sensory changes. (bvsalud.org)
  • The few studies that have evaluated this alteration in the paediatric range have shown that children have less olfactory sensory loss than adults. (bvsalud.org)
  • The authors propose to evaluate the action of SARS-CoV-2 at the intrauterine level regarding the foetus' olfactory sensory impairment. (bvsalud.org)
  • This study aims to assess the olfactory sensory perception of newborns of women who previously tested positive for COVID-19 during pregnancy compared to newborns of women who did not test positive for COVID-19 during pregnancy. (bvsalud.org)
  • It also aims to develop and validate a behavioural evaluation scale of olfactory sensory-perceptual perception in newborns. (bvsalud.org)
Impairment3
  • [ 3 ] A 2002 study showed that the prevalence of objective olfactory impairment in adults older than 53 years is 24.5% and grows more prevalent with age, reaching 62.5 % in those aged 80-97 years. (medscape.com)
  • Extrapolating from these values, there are currently 14 million older adults with some degree of olfactory impairment. (medscape.com)
  • The different facial morphology in the relatives with olfactory impairment as compared to the total group may be an illustration of the contribution of different genetic backgrounds to the occurrence of CL/P via different biological pathways. (hindawi.com)
Chypre2
  • Since 1945, the classification of olfactory families has evolved to include new categories such as chypre and ferns. (carrementbelle.com)
  • The success of this Chypre was such that it became the leader of this large family, which includes fragrances based mainly on oakmoss, ciste-labdanum and bergamot accords. (carrementbelle.com)
Dysfunction4
  • Fracture of the cribriform plate in traumatic settings can disrupt these fine fibers and lead to olfactory dysfunction. (medscape.com)
  • Intranasal exposure to cadmium has been related to olfactory dysfunction in humans and to nasal epithelial damage and altered odorant-guided behavior in rodent models. (rutgers.edu)
  • Evidence exists for the presence of a specific facial phenotype in nonaffected first-degree relatives of persons with CL/P. An increased risk for olfactory dysfunction has also been reported in CL/P-relatives. (hindawi.com)
  • In addition, we show for the first time that olfactory dysfunction in relatives is correlated to a smaller upper nasal region. (hindawi.com)
Fragrance1
  • Housing the most exclusive and distinctive fragrance brands, Amaris is a scent utopia that promises a 360° olfactory experience for the discerning nose. (amarisbeauty.com)
Nose2
  • Odorants can also be perceived by entering the nose posteriorly through the nasopharynx to reach the olfactory receptor via retronasal olfaction. (medscape.com)
  • All the objects in this part of the exhibition prompt unusual gestures and behaviors, allowing for focused attention that highlights the remarkable capacities of our nose and olfactory brain. (sfmcd.org)
Smell2
  • The sense of smell is mediated through stimulation of the olfactory receptor cells by volatile chemicals. (medscape.com)
  • [ 2 , 3 ] Heterozygous loss-of-function mutations of the gene encoding FGFR1 have also been described in individuals with idiopathic hypogonadotropic hypogonadism, normal smell sense, and normal MRI of the olfactory system. (medscape.com)
Odors1
  • These signals, which are not detected consciously as odors by the olfactory system, mediate human autonomic, psychological, and endocrine responses. (medscape.com)
Nerve6
  • Head anatomy with olfactory nerve. (medscape.com)
  • The cribriform plate of the ethmoid bone, separated at the midline by the crista galli, contains multiple small foramina through which the olfactory nerve fibers, or fila olfactoria, traverse. (medscape.com)
  • The glomerular layer is the most superficial layer, consisting of mitral cell dendritic arborizations (glomeruli), olfactory nerve fibers, and periglomerular cells. (medscape.com)
  • Each mitral cell is contacted by at least 1000 olfactory nerve fibers. (medscape.com)
  • Here we use optical imaging techniques to visualize odorant-evoked neurotransmitter release from the olfactory nerve into the brain's olfactory bulbs in vivo in mice. (rutgers.edu)
  • In this study optical imaging revealed significant reductions in odorant-evoked release from the olfactory nerve at a cadmium chloride dose two orders of magnitude less than that required to induce morphological changes in the nerve in the same animals, demonstrating that it is a more sensitive technique for assessing the consequences of intranasal neurotoxicant exposure. (rutgers.edu)
Playlist1
  • Choose the olfactory playlist of your travels and personalize your car with a touch of contemporary design. (drvranjes.us)
Mammalian1
  • The mammalian olfactory system can recognise some 10 000 different odours. (newscientist.com)
Molecules1
  • Activation occurs when odiferous molecules come in contact with specialized processes known as the olfactory vesicles. (medscape.com)
Detects2
  • As a chemical sensor, the olfactory system detects food and influences social and sexual behavior. (medscape.com)
  • PA1-32772 detects Olfactory receptor LS189744 from human samples. (thermofisher.com)
Nasal1
  • The olfactory neuroepithelium is located at the upper area of each nasal chamber adjacent to the cribriform plate, superior nasal septum, and superior-lateral nasal wall. (medscape.com)
Woody1
  • The olfactory family of woody fragrances features odoriferous woods such as sandalwood and cedar , but also leaves and roots as with patchouli and vetiver . (carrementbelle.com)
Bulbs4
  • The main and accessory olfactory epithelia of the mouse, and their first central targets, the main and accessory olfactory bulbs. (frontiersin.org)
  • Panel A is a coronal T1-weighted image of a male with KS showing (abnormal) medially oriented olfactory sulci (black arrows) and normal appearing olfactory bulbs (white arrows). (medscape.com)
  • Panel C is a coronal T1-weighted image of a female with IHH showing normal olfactory bulbs (large arrows) and sulci (small arrows). (medscape.com)
  • Panel D is a coronal T1-weighted image of a female with KS showing lack of olfactory bulbs with shallow olfactory sulci (arrows). (medscape.com)
Basal1
  • Basal cells are stem cells that give rise to the olfactory receptor cells (seen in the image below). (medscape.com)
Classify1
  • These findings support the combinatorial coding scheme and suggest that higher-order brain centers reading out these combinatorial activity patterns may eventually classify olfactory signals according to their biological meaning. (jneurosci.org)
Scents2
  • Living with Scents, featuring over 40 international designers, challenges the way we relate to the world through olfactory design. (sfmcd.org)
  • San Francisco, CA (November 2, 2021) - The Museum of Craft and Design (MCD) is pleased to announce Living with Scents , on view February 12-June 5, 2022, featuring over 40 designers and artists from around the world whose work reflects and participates in the growing culturalization of all things olfactory. (sfmcd.org)
Proteins1
  • The CHD7 protein belongs to a family of proteins that are thought to play a role in the organization of chromatin. (medlineplus.gov)
Genes1
  • 2003). „DEFOG: a practical scheme for deciphering families of genes. (wikipedia.org)
System6
  • Interestingly, the honey bee olfactory system harbors two central parallel pathways, whose functions remain largely unknown. (jneurosci.org)
  • The accessory olfactory system is present in most tetrapods. (frontiersin.org)
  • The accessory olfactory system may differ in morphology even in closely related species, most probably in relation to functional specialization (for a review, see Salazar and Quinteiro, 2009 ). (frontiersin.org)
  • The first functional investigation of the accessory olfactory system pointed to a general chemosensation role. (frontiersin.org)
  • This might be explained by a smaller central olfactory system. (hindawi.com)
  • Almost nothing is known about how the olfactory system is wired to the emotional and cognitive centres of the brain. (newscientist.com)
Smoky1
  • This olfactory family is composed of fragrances with warm, resinous, smoky or even humid notes. (carrementbelle.com)
Morphology1
  • We studied the facial morphology of 88 nonaffected first-degree relatives of patients with CL/P and 33 control subjects without family history of facial clefting by 3D surface imaging and a spatially dense analysis of the images. (hindawi.com)
Epithelial1
  • These specialized epithelial cells give rise to the olfactory vesicles containing kinocilia, which serve as sites of stimulus transduction. (medscape.com)
Respiratory1
  • In neonates, this area is a dense neural sheet, but, in children and adults, the respiratory and olfactory tissues interdigitate. (medscape.com)
Protein2
  • This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. (nih.gov)
  • Galectin-3 is a member of a carbohydrate-binding protein family involved in cell activation and inflammation. (lu.se)
Notes4
  • Faced with a wide range of ingredients, natural or synthetic raw materials, accords and notes, perfumers have developed an olfactory classification. (carrementbelle.com)
  • Freshness, acidity and sunny notes are the common denominators of this olfactory family full of pep! (carrementbelle.com)
  • Fragrances from this family are often composed of virile and masculine notes. (carrementbelle.com)
  • Discover now the unique olfactory notes of the most iconic fragrances in the world. (drvranjes.co.uk)
Patchouli1
  • Like the other families, these accords have evolved and modernized with new ingredients such as patchouli . (carrementbelle.com)
MRNA1
  • Pan troglodytes olfactory receptor 4D6 (LOC466613), mRNA. (genscript.com)
Functional1
  • Complex interactions are now emerging between the main and accessory olfactory systems, both at anatomical and at functional level. (frontiersin.org)
Masculine1
  • There are thus 7 major olfactory families that allow us to "put in order" fragrances according to their main characteristics, whether they are feminine, masculine or mixed. (carrementbelle.com)
Human2
  • The human olfactory receptor gene family. (nih.gov)
  • This study suggests that specific transcription factors and treatment with morphogens can restrict human adult olfactory-derived progenitors to a dopaminergic neuronal lineage. (scirp.org)
Member1
  • If someone else (family member, health professional, etc.) has said anything about problems resulting from your substance use add them to your list. (who.int)
Universe1
  • More precise and closer to reality, this revised classification is still used today to give you a quick overview of the olfactory universe of the composition. (carrementbelle.com)
Adults1
  • In adults, olfactory loss is one of the earliest and most frequent acute clinical manifestations of SARS-CoV-2 infection. (bvsalud.org)