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Integrin alpha5beta1Integrin alpha5IntegrinsIntegrin alpha2beta1Integrin alpha3beta1Integrin alpha2Integrin alpha6Integrin alpha1beta1Integrin beta3Integrin alpha6beta4Integrin alphaVbeta3Integrin alpha ChainsIntegrin alpha3Integrin alpha6beta1Integrin alpha1src-Family KinasesIntegrin alpha4Integrin beta ChainsIntegrin beta4Cell AdhesionAntigens, CD29Integrin alphaVSignal TransductionPhosphorylationDiacylglycerol KinaseI-kappa B KinaseProtein-Serine-Threonine KinasesIntegrin alpha4beta1Phosphatidylinositol 3-KinasesCholine KinaseReceptors, VitronectinMolecular Sequence DataFibronectinsProtein BindingProtein-Tyrosine KinasesCells, CulturedCell LineAmino Acid SequenceCell MovementEnzyme ActivationReceptors, CollagenTransfectionCalcium-Calmodulin-Dependent Protein Kinase KinaseMAP Kinase Signaling SystemProtein KinasesReceptors, FibronectinBinding SitesPlatelet Glycoprotein GPIIb-IIIa ComplexBase SequenceInterleukin-1betaRecombinant ProteinsProto-Oncogene Proteins c-fynCell Line, TumorFocal Adhesion Protein-Tyrosine KinasesMice, KnockoutAntigens, CDProtein Kinase InhibitorsProtein Structure, TertiaryFocal Adhesion Kinase 1Calcium-Calmodulin-Dependent Protein KinasesLamininMutationAMP-Activated Protein KinasesOligopeptidesBlotting, WesternKineticsMice, Inbred C57BLProto-Oncogene Proteins c-hckIsoenzymesalpha 1-AntitrypsinLigandsGene Expression RegulationTumor Cells, CulturedRNA, MessengerTyrosineNF-kappa BProto-Oncogene Proteins c-yesCollagenbeta 2-MicroglobulinProtein Kinase CCell Adhesion MoleculesRecombinant Fusion ProteinsVitronectinAntigens, CD18Phosphotransferases (Alcohol Group Acceptor)CHO CellsTalinRNA, Small InterferingBlood PlateletsCricetinaep38 Mitogen-Activated Protein KinasesAntibodies, MonoclonalGene ExpressionCell MembraneEnzyme InhibitorsExtracellular MatrixProto-Oncogene ProteinsProto-Oncogene Proteins c-aktDown-RegulationReceptors, Adrenergic, alpha
ProteinDifferentiating cellsInhibitorTetraspanin familyHumanCell
Protein3
  • The results obtained indicate that alpha6beta1 is necessary for VEGF expression because the ability of hypoxia to activate HIF-1 and to stimulate VEGF transcription in MDA-MB-435 cells is dependent on alpha6beta1 expression by a mechanism that involves protein kinase C-alpha. (umassmed.edu)
  • The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. (wikipedia.org)
  • This encoded protein is a cell surface glycoprotein that is known to complex with integrins. (wikipedia.org)
Differentiating cells1
  • These results demonstrate that TrkA kinase initiates differentiation, and p75 enhances differentiation by rescuing differentiating cells from apoptosis via the PI3K pathway. (umassmed.edu)
Inhibitor1
  • 24. AEE788: a dual family epidermal growth factor receptor/ErbB2 and vascular endothelial growth factor receptor tyrosine kinase inhibitor with antitumor and antiangiogenic activity. (nih.gov)
Tetraspanin family1
  • CD151 is the first characterized member of the tetraspanin family. (oncotarget.com)
Human1
  • 33. Heregulin-beta is especially potent in activating phosphatidylinositol 3-kinase in nontransformed human mammary epithelial cells. (nih.gov)
Cell1
  • 35. SUCI02 inhibits the erbB-2 tyrosine kinase receptor signaling pathway and arrests the cell cycle in G1 phase in breast cancer cells. (nih.gov)