• any one of a group of congenital hemolytic anemias in which there is no abnormal hemoglobin or spherocytosis and in which there is a defect of glycolysis in the erythrocyte. (icdlist.com)
  • Hereditary spherocytosis and hereditary elliptocytosis are examples of inherited hemolytic anemias. (ghcgenetics.com)
  • Hereditary spherocytosis is the most common congenital hemolytic anemia among Caucasians with an estimated prevalence ranging from 1:2,000 to 1:5,000. (ghcgenetics.com)
  • hypochromic anemia may be caused by iron deficiency from a low iron intake, diminished iron absorption, or excessive iron loss. (icdlist.com)
  • In its most recent guidelines on anemia in pregnancy, the American College of Obstetricians and Gynecologists eliminated different hemoglobin level thresholds to define iron-deficiency anemia in Black and White pregnant persons. (medscape.com)
  • Iron deficiency anemia accounts for 75-95% of the cases of anemia in pregnant women. (medscape.com)
  • Clinical symptoms of iron deficiency anemia include fatigue, headache, restless legs syndrome, and pica (in extreme situations). (medscape.com)
  • The clinical consequences of iron deficiency anemia include preterm delivery, perinatal mortality, and postpartum depression. (medscape.com)
  • [ 4 ] In a Swedish study, Wiegersma et al found that iron deficiency anemia diagnosed at 30 weeks' gestation or earlier increased the risk of autism spectrum disorder, attention-deficit/hyperactivity disorder, and intellectual disability in children. (medscape.com)
  • Go to Iron Deficiency Anemia for complete information on this topic. (medscape.com)
  • Patients with vitamin B-12 deficiency need further workup to determine the level of intrinsic factor to exclude pernicious anemia. (medscape.com)
  • Aldolase A deficiency is an autosomal recessive disorder associated with hereditary hemolytic anemia (Kishi et al. (nih.gov)
  • Red cell pyruvate kinase deficiency is the most common cause of hereditary nonspherocytic hemolytic anemia. (nih.gov)
  • Congenital pernicious anemia (PA), or intrinsic factor deficiency, is a rare disorder characterized by the lack of gastric intrinsic factor in the presence of normal acid secretion and mucosal cytology and the absence of GIF antibodies that are found in the acquired form of pernicious anemia (170900). (nih.gov)
  • See also pernicious anemia due to defect in the receptor for vitamin B12/intrinsic factor (261100). (nih.gov)
  • a familial disorder characterized by anemia with multinuclear erythroblasts, karyorrhexis, asynchrony of nuclear and cytoplasmic maturation, and various nuclear abnormalities of bone marrow erythrocyte precursors (erythroid precursor cells). (icdlist.com)
  • Diamond-Blackfan anemia is a rare (7 per 1 million) autosomal dominant disorder of pure red cell aplasia necessitating life-long transfusion. (medscape.com)
  • the disease is characterized by a moderate to severe macrocytic anemia, occasional neutropenia or thrombocytosis, a normocellular bone marrow with erythroid hypoplasia, and an increased risk of developing leukemia. (icdlist.com)
  • D64.9 is a billable ICD-10 code used to specify a medical diagnosis of anemia, unspecified. (icdlist.com)
  • a condition of inadequate circulating red blood cells (anemia) or insufficient hemoglobin due to premature destruction of red blood cells (erythrocytes). (icdlist.com)
  • The causes of anemia may be classified as impaired red blood cell (RBC) production or increased RBC destruction (hemolytic anemias). (ghcgenetics.com)
  • a form of anemia in which the bone marrow fails to produce adequate numbers of peripheral blood elements. (icdlist.com)
  • Is not recommended for patients suspected to have anemia due to alpha-thalassemia (HBA1 or HBA2). (ghcgenetics.com)
  • Alloantibodies in the Kell and Kx blood group system can cause strong reactions to transfusions of incompatible blood and severe anemia in affected male newborns of Kell-negative mothers. (nih.gov)
  • anemia characterized by a decrease in the ratio of the weight of hemoglobin to the volume of the erythrocyte, i.e., the mean corpuscular hemoglobin concentration is less than normal. (icdlist.com)
  • anemia characterized by decreased or absent iron stores, low serum iron concentration, low transferrin saturation, and low hemoglobin concentration or hematocrit value. (icdlist.com)
  • anemia characterized by larger than normal erythrocytes, increased mean corpuscular volume (mcv) and increased mean corpuscular hemoglobin (mch). (icdlist.com)
  • In an iron-replete population, anemia defined as a value less than the fifth percentile is a hemoglobin level of 11 g/dL or less in the first trimester, 10.5 g/dL or less in the second trimester, and 11 g/dL or less in the third trimester. (medscape.com)
  • Anemia is defined as a decrease in the amount of red blood cells or hemoglobin in the blood. (ghcgenetics.com)
  • acquired hemolytic anemia due to the presence of autoantibodies which agglutinate or lyse the patient's own red blood cells. (icdlist.com)
  • Although red blood cell (RBC) mass increases during pregnancy, plasma volume increases more, resulting in a relative anemia. (medscape.com)
  • The simplest approach to the differential diagnoses of anemia is to differentiate anemias by the mean corpuscular volume (MCV), measured in fL. (medscape.com)
  • a rare congenital hypoplastic anemia that usually presents early in infancy. (icdlist.com)
  • El panel de precisión de Artrogriposis y Síndrome Miasténico congénito de Igenomix se puede utilizar como una herramienta para un diagnóstico preciso que, en última instancia, conduce a un mejor tratamiento y pronóstico de la enfermedad. (igenomix.com)
  • Familial Mediterranean fever (FMF) is divided into two phenotypes: type 1 and type 2. (nih.gov)
  • Go to Anemia, Emergent Management of Acute Anemia, and Chronic Anemia for complete information on these topics. (medscape.com)
  • Sickle cell disease (SCD) is characterized by intermittent vaso-occlusive events and chronic hemolytic anemia. (nih.gov)
  • Chronic hemolysis can result in varying degrees of anemia, jaundice, cholelithiasis, and delayed growth and sexual maturation as well as activating pathways that contribute to the pathophysiology directly. (nih.gov)
  • Celeste Bento is the coordinator of the Congenital Red Blood Cell Diseases Unit at University Hospital Coimbra, Portugal. (cienciavitae.pt)
  • In addition to his research activities, Dr Bento is involved in national scientific and patients associations, and international groups, as the European network for Experts on the Molecular Diagnosis of Myeloproliferative Neoplasm and MPN-related congenital diseases (MPN&MPNr-Euronet), the EuroBloodNet, the Red Cell and Iron Disorders group of EHA and the Human Variome Project. (cienciavitae.pt)
  • In 1957 Ingram demonstrated that sickle cell anemia was caused by the replacement of one of the 287 amino acid residues in the half molecule of hemoglobin (2). (findmedarticle.com)
  • She is a Clinical Laboratory Geneticist certified by the European Board of Medical Genetics, and obtained his PhD in Biomedicine from ICBAS, University of Porto, with a thesis in advances in the Molecular Characterization of Congenital Erythrocytosis. (cienciavitae.pt)
  • A group of familial congenital hemolytic anemias characterized by numerous abnormally shaped erythrocytes which are generally spheroidal. (nih.gov)
  • Although red blood cell (RBC) mass increases during pregnancy, plasma volume increases more, resulting in a relative anemia. (medscape.com)
  • In an iron-replete population, anemia defined as a value less than the fifth percentile is a hemoglobin level of 11 g/dL or less in the first trimester, 10.5 g/dL or less in the second trimester, and 11 g/dL or less in the third trimester. (medscape.com)
  • The simplest approach to the differential diagnoses of anemia is to differentiate anemias by the mean corpuscular volume (MCV), measured in fL. (medscape.com)