AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesInformation ScienceHealth Care
Complement Factor HBronchoalveolar Lavage FluidBronchoalveolar LavageComplement C3b Inactivator ProteinsComplement C3bLungHemolytic-Uremic SyndromeComplement Pathway, AlternativeComplement ActivationTherapeutic IrrigationBronchoscopyMacrophages, AlveolarComplement C4b-Binding ProteinComplement C3-C5 ConvertasesComplement Factor IMacular DegenerationPulmonary AlveoliSarcoidosis, PulmonaryPneumoniaPulmonary FibrosisComplement C3Lung DiseasesComplement Factor BSarcoidosisNeutrophilsAlveolitis, Extrinsic AllergicPulmonary EosinophiliaBronchiBlood ProteinsBronchial HyperreactivityComplement C3dComplement System ProteinsGlomerulonephritis, MembranoproliferativeEosinophilsOvalbuminPneumonia, PneumocystisComplement Inactivating AgentsCell CountAsthmaLeukocyte CountLung InjuryRespiratory HypersensitivityLung Diseases, InterstitialAntigens, CD55Acute Lung InjuryProtein BindingAllergensAntigens, CD46Disease Models, AnimalRespiratory Distress Syndrome, AdultInflammationCytokinesBlood Bactericidal ActivityComplement Inactivator ProteinsMice, Inbred C57BLProperdinPneumocystisComplement Membrane Attack ComplexPneumonia, BacterialPulmonary Alveolar ProteinosisMice, Inbred BALB CBacterial ProteinsEnzyme-Linked Immunosorbent AssayNeisseria meningitidisSurface Plasmon ResonanceBorreliaRepetitive Sequences, Amino AcidBorrelia burgdorferiFicainMeningococcal VaccinesQuartzAntigens, BacterialPulmonary SurfactantsPulmonary Surfactant-Associated Protein DRespiratory MucosaSputumPulmonary EdemaMolecular Sequence DataAdministration, InhalationPulmonary Surfactant-Associated Protein AAerosolsRespiratory Function TestsCD4-CD8 RatioImmunoglobulin ELeukocyte ElastaseBronchial Provocation TestsPneumonia, ViralNeutrophil InfiltrationInvasive Pulmonary AspergillosisHeparinLung Diseases, FungalLung TransplantationLipopolysaccharidesMethacholine ChlorideRelapsing FeverRespiratory SystemInterleukin-5OzoneComplement C3 Convertase, Alternative PathwayComplement C5a
Lavage fluidFluidBronchoscopyCytokinesExposurePneumoniaAirwayCytokineImmunologicalBronchialNonsmokersMetastaticTumorMethodsClinicalEpithelialProcedureVascular EndothMoleculePatientsEpidermalTransformingAsthmaMiceAspirationMucusRisk factorMRNAAdiposeGranulocyteGenesGeneticsAnalysisStudyNuclearStudiesOutcomesGrowth
Lavage fluid5
Fluid3
Bronchoscopy1
  • Thus, we assessed the diagnostic value of fiberoptic bronchoscopy (FOB) and the risk factors associated with PBB. (bvsalud.org)
Cytokines2
  • Gene expression was analyzed in whole lung to characterize immune markers of inflammation: cytokines, chemokines, antioxidant enzymes, and transcription factors. (cdc.gov)
  • Nuclear factor kappa B (NF- κ B) is the most important downstream pathway component that regulates the activity of cytokines, including interleukin (IL)-1 β , IL-6, and tumor necrosis factor (TNF)- α , in airway pathology [ 10 , 11 ]. (hindawi.com)
Exposure5
  • Many factors can affect your risk for membrane may become thicker throughout (diffuse pleural health problems from asbestos exposure. (cdc.gov)
  • Five healthy normal smokers who smoked a cigarette 10 min prior to undergoing a 3 x 60 mL bronchoalveolar lavage (BAL), and five nonsmokers who also underwent BAL but without cigarette smoke exposure were studied. (ersjournals.com)
  • NHIRD does not include some important confounding factors, such as exposure to house dust mites, smoking habits, body mass index, family history or medical compliance. (bmj.com)
  • Role of Exposure and Risk Factors adult-onset nonoccupational asthma. (cdc.gov)
  • In this review, we discuss the various factors of BNNT production that can influence its toxicity followed by summarizing the toxicity findings from in vitro and in vivo studies conducted to date, including a review of particle clearance observed with various exposure routes. (cdc.gov)
Pneumonia5
Airway6
  • Bronchoalveolar lavage (BAL) was analyzed for extent of airway inflammation. (cdc.gov)
  • The effects of cigarette smoking on blood to airway pulmonary permeability to the low-molecular-weight solute urea were investigated, in an attempt to evaluate its use as a dilution marker for bronchoalveolar lavage (BAL) studies. (ersjournals.com)
  • Transforming growth factor-β (TGF-β) is an important pro-fibrotic growth factor implicated in airway remodeling and pulmonary fibrosis ( 6-9 ). (atsjournals.org)
  • To evaluate the role of growth factors in the pathogenesis of airway remodeling, a study was undertaken to study the expression of a known fibrogenic growth factor (TGF-β), of a putative fibrogenic growth factor (EGF) and of a hematopoietic growth factor (GM-CSF) in the central airways of asthmatic and chronic bronchitis patients using immunohistochemistry. (atsjournals.org)
  • Methods Pathways governing airway mucus cell differentiation include SRY (sex determining region Y)-box 2 (SOX2), Notch, forkhead box A3(FOXA3)/SAM pointed domain containing ETS transcription factor (SPDEF), epidermal growth factor (EGF) and the EGF-related neuregulins NRG1α and NRG1β. (bmj.com)
  • Qutayba Hamid interconnects Respiratory disease, Airway and Transforming growth factor in the investigation of issues within Asthma. (research.com)
Cytokine2
Immunological1
  • These results illustrate the combined impact of genetic, lifestyle, and environmental factors in modulating immunological responsivity and emphasize the importance of the exposome in shaping biological responses. (cdc.gov)
Bronchial3
  • its expression was compared with that of epidermal growth factor (EGF) and granulocyte macrophage colony-stimulating factor (GM-CSF) in bronchial mucosal biopsies from 13 normal subjects, 24 asthmatics, and 19 patients with chronic bronchitis. (atsjournals.org)
  • Granulocyte macrophage-colony stimulating factor (GM-CSF) is a hematopoietic growth factor over-expressed in the bronchial mucosa of asthmatics, which is involved in eosinophil and macrophage accumulation in tissues ( 14 , 15 ). (atsjournals.org)
  • We investigated if signs of immune activation are present in bronchial biopsies and bronchoalveolar lavage (BAL) of patients with early-untreated RA without clinical signs of lung involvement. (bmj.com)
Nonsmokers1
  • Positive immunostaining for citrullinated proteins was recorded in bronchoalveolar lavage cells from smokers but not in those from nonsmokers. (nih.gov)
Metastatic1
  • 0.001), number of metastatic sites (p = 0.004), albumin (p = 0.008), CRP (p = 0.022) and IGF-I (p = 0.042) were associated with overall survival, although only gender (p = 0.013), weight loss (p = 0.027), performance status (p = 0.015) and number of metastatic sites (p = 0.021) emerged as independent prognostic factors. (karger.com)
Tumor3
  • Afterward, lipopolysaccharide (LPS)-, lipoteichoic acid (LTA)-, and N -acetylmuramyl- l -alanyl- d -isoglutamine hydrate (MDP)-stimulated leukocyte production of tumor necrosis factor (TNF) and interleukin-10 (IL10) were measured with a canine-specific multiplex assay. (avma.org)
  • After sample incubation, LPS-stimulated leukocyte production of tumor necrosis factor (TNF) and interleukin-10 (IL10) was measured with a canine-specific multiplex assay, and apoptosis and toll-like receptor 4 (TLR4) expression were evaluated via flow cytometry. (avma.org)
  • [ 10 ] Patients who are receiving tumor necrosis factor (TNF) inhibitors are at high risk for nontuberculous mycobacterial (NTM) infections and complications. (medscape.com)
Methods1
  • Other diagnostic methods such as bron- previous studies have focused on the di- choscopy and bronchoalveolar lavage were agnosis of TB or malignancy [5,6,9-12]. (who.int)
Clinical3
  • There is convincing evidence from experimental and clinical studies that BAL can cause influx of neutrophils into the bronchoalveolar space. (nih.gov)
  • CDC's lung injury response efforts have been multifaceted and in addition to being committed to identifying, defining the risk factors or causes of EVALI, CDC is detecting and tracking cases of EVALI in the U. S. Through information collected and committed to communicating actionable recommendations, to state, local and clinical audiences. (cdc.gov)
  • Therefore, each patient's risk factors, the clinical context, and the nodule's characteristics and associated imaging findings are key to determining the etiology. (medscape.com)
Epithelial1
  • Bronchoalveolar lavage was performed to determine epithelial and leukocyte counts, and protein content. (cdc.gov)
Procedure1
  • Nocardiosis is usually an opportunistic a specimen obtained through an invasive infection and most commonly presents as procedure (e.g. bronchoalveolar lavage, pulmonary disease. (who.int)
Vascular Endoth1
  • whereas, vascular endothelial growth factor‑A levels were positively correlated with Angptl7 levels. (spandidos-publications.com)
Molecule2
  • P. multocida expresses a range of virulence factors including a polysaccharide capsule and the variable carbohydrate surface molecule, lipopolysaccharide (LPS). (wikipedia.org)
  • Insulin-like growth factor (IGF)-I is an anabolic molecule implicated in the maintenance of muscle mass and cancer growth. (karger.com)
Patients8
  • In a case-control study involving patients with recent-onset rheumatoid arthritis (RA), we studied interactions between a major environmental risk factor (smoking), major susceptibility genes included in the SE of HLA-DR, and the presence of the most specific autoimmunity known for RA (i.e., antibodies to proteins modified by citrullination). (nih.gov)
  • Identification of shared citrullinated epitopes in the lungs and joints of patients with RA 9 together with local enrichment of ACPA in the bronchoalveolar lavage (BAL) of patients with early untreated RA and in the induced sputum of arthritis-free individuals at risk for developing RA 10 support the notion that RA-associated autoimmunity might indeed initiate in the lung compartment. (bmj.com)
  • microRNA profiling in lung tissue and bronchoalveolar lavage of cigarette smoke-exposed mice and in COPD patients: a translational approach. (dokumen.tips)
  • Patients who would have met the criteria for HCAP should not be empirically treated with antibiotics to cover MDR bacteria unless they have valid risk factors for acquiring MDR organisms. (medscape.com)
  • Mucus cells lining abnormal airways from patients with IPF expressed MUC5B and SOX2 but lacked SAM pointed domain containing ETS transcription factor (SPDEF) and forkhead box A3(FOXA3). (bmj.com)
  • Overwhelming awareness and stressful concerns for the pandemic and female patients with epilepsy were key factors that affect the level of anxiety and depression in PWE. (bvsalud.org)
  • BACKGROUND: The objective of this study was to examine the relationship of mental health status between self-poisoning suicide patients and their family members, and it also sought to identify potential patient's risk and parental factors for the prediction of suicide attempt, anxiety, and depression. (bvsalud.org)
  • Multivariable analyses (multiple logistic regression) were conducted among patients and their matched family members, to identify potential risk factors for self-poisoning suicide, anxiety, and depression. (bvsalud.org)
Epidermal2
  • The discovery of epidermal growth factor receptor (EGFR) mutations in never-smokers has been the most relevant finding ever in non-small cell lung cancer. (aacrjournals.org)
  • Epidermal growth factor (EGF) is another growth factor that participates in repair processes targeted at the resurfacing of a wound with new epithelium ( 12 ). (atsjournals.org)
Transforming1
  • In this study, we considered transforming growth factor-beta1 (TGF-β1) as a strong candidate for paracrine effect of ADSC-CM and investigated collagen synthesis and hyaluronic acid synthase (HAS) expression. (indexindex.com)
Asthma4
  • Is insomnia a risk factor for new-onset asthma? (bmj.com)
  • Objectives To determine whether insomnia at baseline is a risk factor for new-onset asthma. (bmj.com)
  • Conclusions This large population-based study suggests that insomnia at baseline is a risk factor for developing asthma. (bmj.com)
  • pational factors have been implicated in 9 to 15% of all cases of adult asthma. (cdc.gov)
Mice1
  • We investigated the miRNA profile of 523 miRNAs by stem-loop RT-qPCR in lung tissue and cell-free bronchoalveolar lavage (BAL) supernatant of mice exposed to air or cigarette smoke (CS) for 4 or 24 weeks. (dokumen.tips)
Aspiration1
  • Gastro-oesophageal reflux is suspected to be a risk factor for pulmonary aspiration [ 11 ]. (ersjournals.com)
Mucus1
  • Singularly, SPDEF, a transcription factor associated with mucus metaplasia, was rarely detected in mucus cells in IPF. (bmj.com)
Risk factor4
  • The presence of SE genes was a risk factor only for anticitrulline-positive RA, and not for anticitrulline-negative RA. (nih.gov)
  • Bronchopulmonary dysplasia (BPD) is the most critical complication in preterm neonates and is an independent risk factor affecting long-term cognitive development ( 1 - 6 ). (spandidos-publications.com)
  • However, increased PCT after BAL was not an independent risk factor for in-hospital mortality (hazard ratio: 1.689, 95% CI[ 0.626 ,4.563], p=0.301). (mattioli1885journals.com)
  • series (11%), there was no clear risk factor identified. (who.int)
MRNA1
  • Tissue repair was assessed by proliferating cell nuclear antigen (PCNA) immunoreactivity and by expression of keratinocyte growth factor (KGF) mRNA by real-time PCR. (cdc.gov)
Adipose1
  • Recently, the production and secretion of growth factors has been identified as an essential function of adipose-derived stem cells (ADSCs). (indexindex.com)
Granulocyte1
  • His studies deal with areas such as Molecular biology, Immunocytochemistry and Granulocyte macrophage colony-stimulating factor as well as In situ hybridization. (research.com)
Genes1
  • We identified an environmental factor, smoking, that in the context of HLA-DR SE genes may trigger RA-specific immune reactions to citrullinated proteins. (nih.gov)
Genetics1
  • The goal of this study was to investigate the impact of multiple exposomal factors (genetics, lifestyle factors, environmental/occupational exposures) on pulmonary inflammation and corresponding alterations in local/systemic immune parameters. (cdc.gov)
Analysis2
  • Multiple linear regression analysis showed that higher Angptl7 level was an independent protective factor for BPD. (spandidos-publications.com)
  • In addition, the results of IPA analysis indicated that the upstream factor IL-2 initiated the PI3K/AKt/mTOR, mitogen-activated protein kinase (MAPK) pathway and JAK/STAT5 pathway, leading to the liver's involvement in gut microbial immune regulation. (bvsalud.org)
Study1
  • The present study aimed to observe the effects of the BY + EA combination in a COPD rat model and dissect the potential mechanisms via Toll-like receptor (TLR) 4/nuclear factor kappa B (NF- κ B) signaling. (hindawi.com)
Nuclear1
  • As the material increased in purity, there are more high-aspect-ratio particulates and a corresponding distinct increase in cytotoxicity, nuclear factor-B transcription, and inflammasome activation. (cdc.gov)
Studies1
  • Although the data in this field are not decisive and there are some confounding factors in human studies, it can be inferred that the use of any illicit drug with an effect on male sexual health reduces fertility potency. (magiran.com)
Outcomes1
  • Factors and outcomes associated with the decision to treat primary pulmonary coccidioidomycosis. (cdc.gov)
Growth2
  • Tissue remodeling due to extracellular matrix production and fibroblasts proliferation is directly modulated by growth factors classified according to their biological properties into pro-fibrotic and non-fibrotic growth factors ( 6 ). (atsjournals.org)
  • Although there is some evidence showing that GM-CSF may have some fibrogenic properties, it is considered as a hematopoietic growth factor rather than a fibrogenic growth factor ( 6 ). (atsjournals.org)