Receptors, Death DomainCaspase 8ApoptosisFas-Associated Death Domain ProteinAntigens, CD95Receptors, TNF-Related Apoptosis-Inducing LigandCaspasesTNF-Related Apoptosis-Inducing LigandCaspase 9CASP8 and FADD-Like Apoptosis Regulating ProteinFas Ligand ProteinReceptors, Tumor Necrosis FactorBH3 Interacting Domain Death Agonist ProteinSignal TransductionApoptosis Regulatory ProteinsCaspase InhibitorsCaspase 3MitochondriaProto-Oncogene Proteins c-bcl-2Cell Line, TumorCell DeathMembrane GlycoproteinsEnzyme Activationbcl-X ProteinTumor Necrosis Factor-alphaDNA FragmentationCause of DeathCell SurvivalTumor Cells, CulturedReceptors, Tumor Necrosis Factor, Member 25Death Domain Receptor Signaling Adaptor ProteinsEnzyme InhibitorsJurkat CellsDeathCaspase 10Up-RegulationCells, CulturedAntineoplastic AgentsTumor Necrosis Factor Decoy ReceptorsCarrier ProteinsReceptors, Tumor Necrosis Factor, Type IRNA, Small Interferingbcl-2-Associated X ProteinTNF Receptor-Associated Death Domain ProteinAdaptor Proteins, Signal TransducingDown-RegulationCell LineDrug SynergismIntracellular Signaling Peptides and ProteinsTumor Necrosis Factor Ligand Superfamily Member 15Blotting, WesternMice, Inbred C57BLRNA, MessengerTransfectionMice, KnockoutTranscription Factor CHOPDose-Response Relationship, DrugAmino Acid Chloromethyl KetonesReceptors, LDLCytochromes cReceptor, Epidermal Growth FactorReceptor-Interacting Protein Serine-Threonine KinasesDeath, Sudden, CardiacFlow CytometryReverse Transcriptase Polymerase Chain ReactionDrug Resistance, NeoplasmGene Expression Regulation, NeoplasticTime FactorsXenograft Model Antitumor AssaysNF-kappa BTumor Suppressor Protein p53Gene Expression RegulationCell ProliferationModels, BiologicalBrain DeathX-Linked Inhibitor of Apoptosis ProteinLipoproteins, LDLMembrane ProteinsProto-Oncogene ProteinsPhosphorylationLigandsMutationCysteine Proteinase InhibitorsAntibodies, MonoclonalNeoplasmsCytochrome c GroupHeLa CellsFibroblastsInhibitor of Apoptosis ProteinsApoptotic Protease-Activating Factor 1Mice, NudeRecombinant ProteinsReactive Oxygen SpeciesNecrosisFetal DeathReceptors, Aryl HydrocarbonJNK Mitogen-Activated Protein KinasesNarcissusHepatocytesProtein Binding