Juxtaglomerular ApparatusKidney GlomerulusMesangial CellsGlomerular MesangiumGlomerulonephritisOlfactory BulbNephritisProteinuriaImmune Complex DiseasesCells, CulturedGlomerulonephritis, MembranoproliferativeKidneyComplement C3FibrinBasement MembraneKidney TubulesAntigen-Antibody ComplexAlbuminuriaGlomerulonephritis, IGADiabetic NephropathiesRNA, MessengerTransforming Growth Factor betaAntigens, Thy-1Rats, Sprague-DawleyCell DivisionPlatelet-Derived Growth FactorCollagen Type IVImmunohistochemistryTransforming Growth Factor beta1Glomerulosclerosis, Focal SegmentalFibronectinsImmunoglobulin GInterleukin-1GlucoseExtracellular MatrixProtein Kinase CGene ExpressionAngiotensin IIEnzyme ActivationHypertrophyPodocytesCollagenMitogen-Activated Protein KinasesConnective Tissue Growth FactorSignal TransductionEnzyme InhibitorsExtracellular Matrix ProteinsDiabetes Mellitus, ExperimentalPhospholipases ARats, WistarPhosphorylationPhospholipases A2Dose-Response Relationship, DrugThymidineGene Expression RegulationChemokine CCL2Blotting, WesternIsoantibodiesUp-RegulationBlotting, NorthernProto-Oncogene Proteins c-sisImmunoglobulin ANeutral CeramidaseDinoprostoneKidney DiseasesGroup II Phospholipases A2EndothelinsDNAIntercellular Signaling Peptides and ProteinsLupus NephritisIsoenzymesTrimeresurusFluorescent Antibody TechniqueEndothelin-1Nitric OxideIntegrin alpha1beta1Mitogen-Activated Protein Kinase 1ActinsNitric Oxide SynthaseApoptosisCollagen Type INephrotic SyndromeReverse Transcriptase Polymerase Chain ReactionReactive Oxygen SpeciesImmediate-Early ProteinsRats, Inbred StrainsHyperglycemiaAntibodiesCulture Media, ConditionedPurinergic AgonistsNF-kappa BTetradecanoylphorbol AcetatePlasminogen Activator Inhibitor 1Tumor Necrosis Factor-alphaCell LineMitogen-Activated Protein Kinase 13Base SequenceCalcium-Calmodulin-Dependent Protein KinasesTime FactorsCalcium