• heme
  • It is a member of the class III extradiol dioxygenase family, a group of enzymes that use a non-heme Fe(II) to cleave aromatic rings between a hydroxylated carbon and an adjacent non-hydroxylated carbon [ PMID: 16849108 ]. (ebi.ac.uk)
  • A non-heme [(L4Me4)Fe(III)] + 3 complex that mimics the reactivity of intradiol dioxygenases, and a heme [T(o-Cl)PPFe] complex catalyzing the stepwise oxidation of cyclohexane to adipic acid, were also studied. (diva-portal.org)
  • degradation
  • This study reveals that aromatic hydroxylation is a prerequisite for proper degradation of bicyclics with aromatic and alicyclic rings by DK17 and confirms the unique ability of the DK17 o -xylene dioxygenase to perform distinct regioselective hydroxylations. (asm.org)