Extracts hela cells. Medical search. Frequent questions

In the present study we investigated the efficacy of Organic extracts of Nigella sativa seed powder for its clonogenic inhibition and induction of apoptosis in HeLa cancer cell. (biomedcentral.com)
All three extracts induced apoptosis in HeLa cells. (biomedcentral.com)
Apoptosis an active physiological process resulting in cellular self-destruction of unwanted cells is absent in cancer cells. (biomedcentral.com)
Apoptosis profile shows (shown that) many cells undergoing apoptosis after treatment. (chemoprev.org)
Thus, EBMD potentially inhibits activation of NF-κB pathway and triggers apoptosis on HeLa cells. (chemoprev.org)
Apoptosis of the cells was analyzed by flow cytometry using an Annexin V and propidium iodide binding method. (nel.edu)
Total apoptosis (about 12%) and no significant alteration in cell cycle were confirmed for SGE of A. variegatum and R. appendiculatus, and additionally SGE of 5-day fed I. ricinus females (IC(50) 0.64 mg/ml). (nel.edu)
Cell cycle analysis suggested activation of apoptosis, without arresting cell cycle progression. (nature.com)
Annexin V-propidium iodide double-staining demonstrated that Sapota fruit extracts potentiate apoptosis rather than necrosis in cancer cells. (nature.com)
Fluorescence-activated cell sorting analysis after annexin V-fluorescein isothiocyanate and propidium iodide (annexin V-FITC-PI) dual staining method was done to ascertain early stage of apoptosis, if any. (jcimjournal.com)
Annexin-V-FITC positivity of cells up to 11.72% as compared to the untreated control revealed early state of TO-induced apoptosis. (jcimjournal.com)
Chemical characterization of non‐psychoactive Cannabis sativa L. extracts, in vitro antiproliferative activity and induction of apoptosis in chronic myelogenous leukaemia cancer cells. (jptcp.com)

Methanolic, n-Hexane and chloroform extracts of Nigella sativa seedz effectively killed HeLa cells. (biomedcentral.com)
The IC 50 values of methanolic, n-hexane, and chloroform extracts of Nigella sativa were 2.28 μg/ml, 2.20 μg/ml and 0.41 ng/ml, respectively. (biomedcentral.com)
The present study examined the chemical profiles and biological properties of J. secunda extracts obtained with different solvents (dichloromethane, ethyl acetate, methanolic and aqueous: macerated and infused). (researchgate.net)
Study of combined methanolic extract of whole plant isolated one cembrane-type diterpenoid, two benzenoids, five flavonoids, and six phenyl propanoids. (stuartxchange.org)
Here we show that methanolic extracts of Sapota fruit (MESF) induces cytotoxicity in a dose-dependent manner in cancer cell lines. (nature.com)
This study aimed to examine if methanolic extracts of Pulsatilla vulgaris Mill. (bvsalud.org)
The methanolic extracts of P. vulgaris enhanced apoptotic death and deregulated cellular proliferation, differentiation, and progression toward the neoplastic phenotype by altering key signaling molecules required for cell cycle progression. (bvsalud.org)

To characterize RA33, the antigen was purified from HeLa cell nuclear extracts to more than 90% homogeneity by affinity chromatography on heparin-Sepharose and by chromatofocusing. (jci.org)
Comparison of nuclear splicing extracts from human HeLa and Drosophila Kc cells has revealed species-specificity, consistent with the observed size differences. (umd.edu)
In contrast to previous results, however, an upstream cryptic 5' splice site is activated when the wild-type myosin intron is tested in a human HeLa cell nuclear extract, resulting in the removal of a 98 nucleotide intron. (umd.edu)
Gel shift experiments using nuclear extracts from TNF-alpha-treated cells and oligonucleotides containing the tTG nuclear factor (NF)-kappa B motif revealed increased binding, concordant with mRNA data. (nih.gov)

The cytotoxicity of etoposide and VPA to a UKF-NB-4 neuroblastoma cell line was evaluated with MTT assay. (nel.edu)
They also indicate that the impact of VPA on cytotoxicity of etoposide in these tumor cells varies depending on the sequence of cultivation of the cells with the drugs. (nel.edu)
In contrast, the reversed combination (preincubation of the cells with VPA before their treating with etoposide) did not give any increase in etoposide cytotoxicity. (nel.edu)
In a preliminary study it has been shown that phenolic antioxidants such as methyl 4- O -galloylchlorogenate and 4- O -galloylchlorogenic acid derived from Sapota fruits can induce cytotoxicity in colon cancer cells 23 . (nature.com)
Confluent monolayers of cells were used to test the cytotoxicity ethanolic extracts. (jptcp.com)
None of the compounds inhibited luciferase expression driven by the minimal thymidine kinase promoter (pTK), indicating the lack of general cytotoxicity for luciferase enzyme inhibition at the 50 µM concentration in both of these cell lines. (bvsalud.org)
The cytotoxicity and chemical composition of P. vulgaris leaves and root extracts were also determined. (bvsalud.org)
Active constituents showed differentiated activity towards Giardia lamblia, Trypanosoma cruzi, several Leishmania strains, Plasmodium falciparum and cytotoxicity against HeLa cells. (lu.se)

SGE of all ticks examined suppressed HeLa cell proliferation in a dose dependent manner. (nel.edu)
Other phenolic constituents such as phytic acid was shown to exhibit anticancer properties through the regulation of vital cellular functions such as signal transduction, cell proliferation and differentiation ( Vucenik and Shamsuddin, 2006 ). (scialert.net)
Opposing function of MYBBP1A in proliferation and migration of head and neck squamous cell carcinoma cells. (nih.gov)
Cell proliferation was reduced in a time-dependent manner of drug exposure as revealed from BrdU incorporation and migration studies. (jcimjournal.com)
Effects of Thuja occidentalis ethanolic extract on cellular proliferation tested by BrdU incorporation assay Cells were exposed to three different concentration of Thuja occidentalis ethanolic extract for 6, 12 and 24 h along with incorporation of BrdU. (jcimjournal.com)
can inhibit HeLa cell proliferation through the modulation of cancer-related signaling pathways. (bvsalud.org)

HeLa whole cell extracts were collected in lysis buffer after 3 hour treatment with Calyculin A (50 nM) or vehicle (DMSO) in serum-free media. (abcam.com)
Immunoprecipitation of GM130 protein from HeLa whole cell extracts using 5 μg of GM130 antibody (GTX130351). (genetex.com)
Various whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with GM130 antibody (GTX130351) diluted by 1:1000. (genetex.com)

HeLa cells are adherent cells (they stick to surfaces) and maintain contact inhibition in vitro. (abcam.com)
Cell growth inhibition activity of SGE was measured by the MTT assay. (nel.edu)
HeLa cells treated with 75 μg of a crude leaf extract of A. muricata showing 80% of cell inhibition. (ingentaconnect.com)
Effect of aqueous and alcoholic plant extracts on inhibition of some types of microbes and causing spoilage of food. (jptcp.com)

Extracts of 6-month-old bud exhibited a significant in vitro anticancer activity against HeLa cancer cells with IC50 value of 56.8 µg/mL. (unboundmedicine.com)
RNA interference-mediated depletion of HSPC117 inhibited maturation of intron-containing pre-tRNA both in vitro and in living cells. (nih.gov)
details] Aneuploidy studies in human cells exposed in vitro to GSM-900 MHz radiofrequency radiation using FISH [med. (emf-portal.org)
To study the possible anticancer and antiproliferative activities of ethanolic leaf extract of Thuja occidentalis (TO) on A549 non-small lung carcinoma cells in vitro . (jcimjournal.com)
In vitro antiproliferative potential was determined by MTT assay [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] on HeLa cell lines. (jptcp.com)
In vitro antioxidant, antimicrobial and antiproliferative studies of four different extracts of Orthosiphon stamineus, Gynura procumbens and Ficus deltoidea. (jptcp.com)
In vitro antiproliferative activity of selected medicinal plants from the North-West of Morocco on several cancer cell lines. (jptcp.com)

This research is to investigate anticancer mechanism of Phaleria macrocarpa fruits extracts (EBMD) in NF-κB pathway. (chemoprev.org)
Impact of histone deacetylase inhibitor valproic acid on the anticancer effect of etoposide on neuroblastoma cells. (nel.edu)
In this study, we investigated the effect of this anticancer drug alone and in combination with a histone deacetylase (HDAC) inhibitor, valproic acid (VPA), on a human UKF-NB-4 neuroblastoma cell line. (nel.edu)
Groh T, Hrabeta J, Poljakova J, Eckschlager T, Stiborova M. Impact of histone deacetylase inhibitor valproic acid on the anticancer effect of etoposide on neuroblastoma cells. (nel.edu)
Studies have explored the anticancer properties of different fruits, both in terms of their extracts and bioactive ingredients. (nature.com)
Comparative anticancer activities of Ficus carica and Ficus salicifolia latex in MDA-MB-231 cells. (jptcp.com)

The cell line was derived from cervical cancer cells taken from Henrietta Lacks, in 1951. (abcam.com)

Our analyses show that there is a significant antiviral activity associated with proteins in the extract, although other compounds also seem to contribute to inhibiting the replication cycle of these viruses. (frontiersin.org)
Ethidium Bromide treated cells are depleted of mitochondrial DNA (mtDNA) and mtDNA encoded proteins. (cellsignal.com)
Proteolytic degradation is critical to the maintenance of appropriate levels of short-lived and regulatory proteins as important and diverse as those involved in cellular metabolism, heat shock and stress response, antigen presentation, modulation of cell surface receptors and ion channels, cell cycle regulation, transcription, and signalling factors. (novusbio.com)
The ubiquitin-proteasome pathway deconstructs most proteins in the eukaryotic cell cytosol and nucleus. (novusbio.com)
Results Arnica montana at the 2c dilution (final concentration of sesquiterpene lactones in cell culture = 10 −8 mol/L) significantly stimulated the expression of three genes which code for regulatory proteins of the extracellular matrix, namely FN1 (fibronectin 1, % increase of 21.8 ± standard error of the mean 4.6), low-density lipoprotein-receptor-related protein 1 (% increase of 33.4 ± 6.1) and heparan sulphate proteoglycan 2 (% increase of 21.6 ± 9.1). (thieme-connect.com)
The 1-Step High-Yield IVT System uses modified HeLa cell extracts to take advantage of the robust human translation machinery and generate functional full-length proteins. (thermofisher.com)
The advantages of using the 1-Step Human High-Yield IVT Kits over traditional in vivo expression systems include the ability to express toxic or insoluble proteins, easily perform protein labeling with modified amino-acids and reduce the time and cost of expressing human proteins in tissue culture cells. (thermofisher.com)
Treatment of human Hep G2 cells with 1 ng/ml TNF-alpha increased [14C]putrescine cross-linking to cellular proteins. (nih.gov)
In vivo studies further confirmed the inhibitory effect of celastrol on the expression of HIF-1α proteins, leading to a decreased growth of Hep3B cells in a xenograft tumor model. (spandidos-publications.com)
The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. (thermofisher.com)
Cell 75:495, 1993), and a series of unique E6-AP homologous proteins have been identified (Huibregtse et al. (justia.com)
These approaches promise to enable researchers to assess, on a large scale, both expression level and functional state of the proteins that carry out most functions in a cell. (lu.se)
We could verify 4000 proteins by MS1t analysis from HeLA extracts. (lu.se)
We also identified low-abundant proteins with functions related to (i) cell signaling, (ii) immune system regulators, and (iii) proteins regulating folding, sorting, and degradation, as well as (iv) vesicular transport proteins. (lu.se)

Minimum inhibitory concentration (MIC) performed for ethanolic extract of Cannabis sativa at various concentrations of dilutions. (jptcp.com)
A dose dependent curve was obtained by plotting concentration of dose and cell viability. (jptcp.com)

As your recommendaion, the Jurkat cells treated with anti Fas antibody to induce cleavage is positive control. (abcam.com)
Western blot analysis of extracts from HeLa cells, cultured in the absence (-) or presence of Ethidium Bromide (+), using COX2/MT-CO2 Antibody (upper) or GAPDH (D16H11) XP ® Rabbit mAb #5174 (lower). (cellsignal.com)
Western blot analysis of extracts from various cell lines using COX2/MT-CO2 Antibody (upper) or GAPDH (D16H11) XP ® Rabbit mAb #5174 (lower). (cellsignal.com)
Western blot analysis of extracts from 293T cells, mock transfected (lane 1) or transiently transfected with plasmid encoding Myc/DDK-tagged COX2/MT-CO2 protein (lane 2), using COX2/MT-CO2 Antibody (upper), Myc-Tag (71D10) Rabbit mAb #2278 (middle), or GAPDH (D16H11) XP ® Rabbit mAb #5174 (lower). (cellsignal.com)
Western Blot: LMP7/PSMB8 Antibody [NB120-3329] - Analysis of HeLa cell extract. (novusbio.com)
Based on the antibody intensities and the COX and LDH activity, Müller glial cells (MGCs) had the lowest capacity for glycolysis, aerobic glycolysis, and OXPHOS. (molvis.org)
Antibody against human SS-A (Ro), detectable bands at SS-A 60kD by Western blot immunoassay at 1:100 dilution using Hep-2 cellular extract blot. (calbiotech.com)

The 80% ethanolic stem bark extract exhibited the highest activity in the ABTS assay, equal to 551.82. (researchgate.net)
Ethanolic leaf extract of TO demonstrated apoptotic and antiproliferative potentials against A549 cell line. (jcimjournal.com)
Effects of Thuja occidentalis ethanolic extract on viability of A549 cell line (A) and L-132 cell line (B) Cells were exposed to Thuja occidentalis ethanolic extract for 24 h at different concentrations and the cell viability was determined by MTT assay. (jcimjournal.com)
Effects of Thuja occidentalis ethanolic extract on A549 cell migration (Light microscopy, ×20) Wound-healing assays were performed to assess cell migration. (jcimjournal.com)
Antibacterial potential of extracts is explainable on bases of phytochemical composition as ethanolic extract strongly inhibits bacterial growth. (jptcp.com)

Etoposide and VPA were found as cycle phase specific drugs that are cytotoxic to human UKF-NB-4 neuroblastoma cells used either as single drugs or both together. (nel.edu)
However, whereas VPA might sensitize the cells to etoposide, inappropriate sequence of cultivation of the cells with VPA can decrease the etoposide cytotoxic efficacy. (nel.edu)
Ficus carica, Ficus sycomorus and Euphorbia tirucalli latex extracts: Phytochemical screening, antioxidant and cytotoxic properties. (jptcp.com)
It has also been determined that Achillea species generally exhibit quite high cytotoxic activity against the HeLa cell line. (tubitak.gov.tr)

Western Blot and TUNEL results suggested that Nigella sativa seed extracts regulated the expression of pro- and anti- apoptotic genes, indicating its possible development as a potential therapeutic agent for cervical cancer upon further investigation. (biomedcentral.com)
Western blot shows an increase in HSP70 that occurs when cells are exposed to temperatures that are higher than normal. (moleculardevices.com)

No attempts have been made to qualify this product on blots made with HeLa cell, or any other antigen source. (calbiotech.com)

These SP constitute an important ingredient of cell walls and get harvested by suitable extraction or precipitation method, followed by purification, characterization and biological studies (Fig. 2 ). (springer.com)

Here, we assessed the potential antiviral activity of aqueous extracts obtained from two brown macroalgae, namely Macrocystis pyrifera and Durvillaea antarctica against HSVs. (frontiersin.org)
This study analysed phytochemical composition of medicinal plants leaves extracts in aqueous, acetone and methanol solvent. (jptcp.com)

Thus, the purpose of this presented research was to assess the phytochemical profile of extracts from aerial parts of G. robertianum, commercially available in Poland and to study th. (researchgate.net)
Furthermore, the total flavonoid and phenolic contents were determined and LC-MS/MS analysis was performed to reveal the phytochemical profile of the investigated extracts. (tubitak.gov.tr)

HeLa cells are human epithelial cells from a fatal cervical carcinoma. (abcam.com)
Epithelial cells can be taken from the eye, urethra (remove purulent exudate), endocervix (remove purulent exudate), and rectum. (medscape.com)
Obtain specimen from epithelial cells in the infected site. (medscape.com)

Taken together, these findings suggest that these algae extracts may be potential phytotherapeutics against HSVs and may be useful for the treatment and reduction of common herpetic manifestations in humans. (frontiersin.org)

To further study the role of tTG in liver disease, we initiated investigations into the effect of a proinflammatory mediator, tumor necrosis factor (TNF)-alpha, on tTG activity in cultured liver cells. (nih.gov)
NF-κB is a transcription factor that plays a pivotal role in the highly specific pattern of gene expression observed for immune, inflammatory and acute phase response genes, including interleukin 1, interleukin 8, tumor necrosis factor and certain cell adhesion molecules. (justia.com)

In the present study, we performed comprehensive LC-MS chemical profiling and biological tests of Vepris boiviniana leaves and stem bark extracts of different polarities. (researchgate.net)
In this study, poly(ε-caprolactone) (PCL)/gelatin (GEL) electrospun nanofibers loaded with two different concentrations of Pinus radiata bark extracts (PEs) were fabricated via electrospinning for wound healing applications. (mdpi.com)

My research interest is phytochemical analysis of plant extracts, plant based food products and dietary supplements. (researchgate.net)

The highest 1,1-diphenyl-2-picrylhydrazyl (DPPH) activity was observed in the extract of 1-year-old buds followed by 6-month-old buds, with 50% of free radical scavenging (IC50) values of 64.6 and 73.5 µg/mL, respectively. (unboundmedicine.com)

Extracts from 2-day fed R. appendiculatus females (IC(50) 0.22 mg/ml SGE soluble protein) and 9-day fed A. variegatum females (IC(50) 0.30 mg/ml) were most potent. (nel.edu)
Immunoprecipitation of COX2/MT-CO2 protein from HeLa cell extracts. (cellsignal.com)
This continuous-exchange cell-free (CECF) system enables protein expression in an overnight incubation of up to 750 µg/mL. (thermofisher.com)
The 1-Step Human High-Yield IVT Kits are cell-free protein expression systems that provide all of the essential components required for transcription and translation. (thermofisher.com)
Our goals were twofold: 1) to characterize the gene expression, protein expression, and activity of key synthesizing and regulating enzymes of energy metabolism in the whole mouse retina, retinal compartments, and/or cells and 2) to provide an integrative analysis of the results related to function. (molvis.org)
The success of proteomics experiments, such as studies of protein function and cell signaling pathways, ultimately de- pends on how well the protein content in samples is identified and annotated. (lu.se)
RNA-Seq with the T98G glioblastoma cell line treated with GH showed more than an 80-fold reduction in thioredoxin interacting protein (TXNIP) expression, indicating that GH has a direct effect on regulating a key gene involved in the homeostasis of cellular glucose. (bvsalud.org)

we noted that a naturally larger (150 nucleotide) intron from the ftz gene is efficiently spliced in Kc cell extracts that do not splice enlarged introns (of 84, 90, 150 or 350 nucleotides) derived from the 74 nucleotide white intron. (umd.edu)

Our current study claims the discovery of gnetin H (GH) as a novel glycolysis inhibitor that can decrease metabolic activity and lactic acid synthesis and displays a strong cytostatic effect in melanoma and glioblastoma cells. (bvsalud.org)

The results found here warrant further studies of combined treatment of neuroblastoma cells with etoposide with HDAC inhibitors and may help in the design of new protocols geared to the treatment of high risk neuroblastomas. (nel.edu)

Double staining was performed to determine the apoptotic cells. (chemoprev.org)
Annexin V-FITC was used to detect apoptotic cells. (nel.edu)

In the experimental analysis, Graviola leaves were collected, and the extracted components were tested against the HeLa cell line and PC3 cell line. (ingentaconnect.com)
Materials and Methods Macrophages derived from the THP-1 cell line were differentiated with interleukin-4 to induce a 'wound-healing'-like phenotype, and treated with various dilutions of Arnica m . centesimal (100 times) dilutions (2c, 3c, 5c, 9c, and 15c) or control solvent for 24 hours. (thieme-connect.com)
Macrophages derived from the THP-1 cell line were differentiated with IL-4 to induce a 'wound-healing'-like phenotype. (thieme-connect.com)

As observed with the 74 nucleotide second intron of the Drosophila white gene, the wild-type myosin intron is accurately spliced in a homologous extract, and increasing the size by 16 nucleotides both eliminates splicing in the Drosophila extract and allows accurate splicing in the human extract. (umd.edu)

Cells treated with Calyculin A accumulate serine/threonine phosphorylation making them a strong positive control for phospho-threonine or phospho-serine specific antibodies. (abcam.com)
The immunoreactivity levels of well-characterized antibodies, for all major retinal cells and their compartments, were obtained using our established semiquantitative confocal and imaging techniques. (molvis.org)

Fucan represents a family of water soluble, SP rich in sulfated l -fucose, extracted from extracellular matrix of these weeds (Li et al. (springer.com)
Conclusion The results support evidence that the extracellular matrix is a potential therapeutic target of Arnica m., with positive effects on cell adhesion and migration during tissue development and healing. (thieme-connect.com)

Both extracts showed antiviral activity against acyclovir-sensitive and acyclovir-resistant HSV-1 and HSV-2. (frontiersin.org)
By inhibiting the topoisomerase II enzyme activity in cancer cells, this drug leads to DNA damage and subsequently to cell death. (nel.edu)
Anti-proliferative activity and apoptotic effect of tick salivary gland extracts on human HeLa cells. (nel.edu)
Kazimírová M, Dovinová I, Rolníková T, Tóthová L, Hunáková L. Anti-proliferative activity and apoptotic effect of tick salivary gland extracts on human HeLa cells. (nel.edu)
Using activity-guided purification of tRNA ligase from HeLa cell extracts, we identified HSPC117, a member of the UPF0027 (RtcB) family, as the essential subunit of a tRNA ligase complex. (nih.gov)
Hep G2 cells, transiently transfected with a luciferase reporter containing 1.67 kb of the human tTG promoter, showed an increase in reporter activity after addition of TNF-alpha. (nih.gov)
Furthermore, Hep G2 cells are incapable of upmodulating tTG promoter reporter activity in the presence of TNF-alpha when those cells overexpress a transdominant, negative mutant NF-kappa B subunit. (nih.gov)
Celastrol showed a potent inhibitory activity against HIF-1 activation induced by hypoxia in various human cancer cell lines. (spandidos-publications.com)
1990. Cell replication and unscheduled DNA synthesis (UDS) activity of low molecular weight chlorinated paraffins in the rat liver in vivo. (cdc.gov)

In total, 60 bioactive compounds were tentatively identified in all extracts. (researchgate.net)
Bioactive SP extracted from seaweeds can be classified into three types. (springer.com)

In addition, FN1, unlike other candidate genes, was upregulated in cells treated with higher dilutions/dynamisations (3c, 5c, and 15c) of Arnica m. (thieme-connect.com)
mRNA expression data of energy-related genes were extracted from our whole retinal Affymetrix microarray data. (molvis.org)
DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract. (wikidata.org)

Respiratory or enteric viral isolates obtained from PIM specimens using poliovirus-permissive cell lines are also considered PIM. (cdc.gov)
Extracted nucleic acid and specimens that may contain only OPV (i.e. (cdc.gov)

TO demonstrated a dose-dependent decrease in viability of A549 cells after 24 h of exposure. (jcimjournal.com)

The effect of etoposide and VPA on the cell cycle distribution was determined by flow cytometric analysis using propidium iodide staining. (nel.edu)
Cell cycle analysis and quantification of DNA fragmentation was performed by DNA staining with propidium iodide. (nel.edu)

The study shows that tumour cell growth suppressant(s) and/or apoptotic triggers are present in tick salivary glands, however, further research into the characteristics and mode of action of such natural substances is necessary. (nel.edu)

Cell viability was ascertained through 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay after deployment of TO in different doses. (jcimjournal.com)

Several major species of E2 enzymes have been characterized in mammalian cells, plants, and yeast. (justia.com)
The objective of this study was to evaluate the biological activities and chemical fingerprint profiles of the extracts obtained from twelve Achillea L. species (A. lycaonica, A. biebersteinii (syn: A. arabica), A. kotschyi subsp. (tubitak.gov.tr)
A. kotschyi and A. nobilis species were detected to have very high antioxidant potential as well as high total phenolic content (260.00 ± 3.38 and 282.97 ± 3.14 ?g of PEs mg extract?1, respectively). (tubitak.gov.tr)
According to the LC-MS/ MS results, A. kotschyi and A. nobilis species were found to contain very high concentrations of chlorogenic acid (55812.20 and 46407 ?g analyte g extract?1). (tubitak.gov.tr)

Compared to most of the other glycolysis inhibitors used in combination with the complex-1 mitochondrial inhibitor phenformin (Phen), GH more potently inhibited cell growth. (bvsalud.org)
These findings suggest that the concurrent use of the glycolytic inhibitor GH with a complex-1 mitochondrial inhibitor could be used as a powerful tool for inducing metabolic catastrophe in cancer cells and reducing their growth. (bvsalud.org)

These medicinal systems have identified more than 700 individual herbal extracts as well as several drug preparations which claim to treat and/or prevent several diseases including cancer [ 11 ]. (biomedcentral.com)
A bioassay screening against protozoa parasites of several Tacana medicinal plants gave Hyptis brevipes (Id'ene eidhue), traditionally used as decoction for intestinal parasites, as the most active extract. (lu.se)

Tumor-treating fields elicit a conditional vulnerability to ionizing radiation via the downregulation of BRCA1 signaling and reduced DNA double-strand break repair capacity in non-small cell lung cancer cell lines [med. (emf-portal.org)
Since aerobic glycolysis was first observed in tumors almost a century ago by Otto Warburg, the field of cancer cell metabolism has sparked the interest of scientists around the world as it might offer new avenues of treatment for malignant cells. (bvsalud.org)

Anatomy9

Organisms6

Chemicals and Drugs33

Analytical, Diagnostic and Therapeutic Techniques and Equipment9

Phenomena and Processes31

Information Science3

Health Care1

Apoptosis12

Methanolic7

Nuclear4

Cytotoxicity8

Proliferation6

Whole cell extracts3

Inhibition4

Vitro7

Anticancer6

Cervical cancer cells1

Proteins14

Concentration2

Antibody7

Ethanolic5

Cytotoxic4

Western blot2

Antigen1

Characterization1

Aqueous2

Phytochemical profile2

Epithelial cells3

Humans1

Necrosis2

Bark extracts2

Plant extracts1

IC501

Protein7

Introns1

Glioblastoma1

HDAC1

Apoptotic cells2

Line3

Drosophila1

Antibodies2

Extracellular2

Activity9

Bioactive2

Genes3

Specimens2

Dose1

Analysis2

Triggers1

Assay1

Species4

Mitochondrial2

Medicinal2

Cancer cell2